CN105362914A - Traditional Chinese medicinal composition for treating chronic gastritis - Google Patents
Traditional Chinese medicinal composition for treating chronic gastritis Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicinal composition for treating chronic gastritis. According to the formula I, the traditional Chinese medicinal composition is prepared from the following components: perilla stem, bergamot, fructus amomi, dried tangerine or orange peel, szechwan Chinaberry fruits, aspongopus, radices paeoniae alba, fructus alpiniae oxyphyllae, cortex cinnamomi, corydalis tuber roasted with vinegar, and prepared rhizoma coptidis with rhizoma zingiberis recens juice; according to the formula II, the traditional Chinese medicinal composition is prepared from the following components: rhizoma atractylodis, rhizoma alpiniae officinarum, rhizoma cyperi, fruits of polygonum orientale, raw malt, pawpaw, fructus amomi rotundus, radix bupleuri and endothelium corneum gigeriae galli. The traditional Chinese medicinal composition adopting the formula I can be prepared into the medicine for oral administration, the traditional Chinese medicinal composition adopting the formula II can be prepared into an acupoint plaster, and the medicine for oral administration and the acupoint plaster can be applied through combination. The traditional Chinese medicinal composition has the efficacies of soothing the liver and regulating qi, harmonizing the stomach and relieving pain, as well as invigorating spleen to eliminate dampness, has the functions of protecting the gastric mucosa and enhancing the disease resistance of the gastric mucosa while regulating the gastrointestinal function and eliminating the inflammation of the mucosa, and can effectively improve and eliminate the symptoms including gastral cavity swelling pain, poor appetite, hiccup, upward flowing qi, acid regurgitation, burning sensation and the like, so that the problem that chronic gastritis is difficult to treat and has frequent relapse is completely solved.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic gastritis, belong to traditional Chinese medicine field.
Background technology
Chronic gastritis (chronicgestritis) means chronic inflammatory disease or the atrophic lesion of the gastric mucosa that different pathogeny causes, after its essence is that gastric epithelial suffers repeatedly to damage, due to the regeneration capacity that mucosa is special, so that mucosa is reconstructed, and finally cause the atrophy of irreversible intrinsic gastric gland body, even disappear.Primary disease is very common, accounts for and accepts gastroscopy patient's 80 ~ 90%, and male, more than women, increases sickness rate with the age and increases gradually.
Chronic superficial gastritis, atrophic gastritis, chronic erosive gastritis are modal chronic gastritiss.Chronic gastritis of children, chronic gastritis in recent years clinical onset rate also raise gradually.Chronic erosive gastritis, also known as gastritis verrucosa or varioliform gastritis generally rarely seen glutted, indigestion symptom such as pantothenic acid, belch, irregularities stomachache after meal.General medicine is difficult to radical cure, and omeprazole, lansoprazole can only respites, and in fact can cause further infringement to gastric mucosa, long-term taking can cause the state of an illness heavier.But Chinese traditional treatment obviously can improve symptom, and improving mucosal blood flow, immunity moderation, increasing gastric mucosal barrier, improve the aspects such as gastric living environment and there is irreplaceable advantage.
Summary of the invention
The present invention is directed to existing treatment by Chinese herbs chronic gastritis deficiency, provide a kind of Chinese medicine composition for the treatment of chronic gastritis, treatment chronic gastritis especially chronic erosive gastritis, determined curative effect.
Technical solution of the present invention is as follows: a kind of Chinese medicine composition for the treatment of chronic gastritis, comprises the crude drug of following component by weight:
Component one: Caulis Perillae 5-10 part, Fructus Citri Sarcodactylis 5-10 part, Fructus Amomi 6-12 part, Pericarpium Citri Reticulatae 5-10 part, Fructus Toosendan 4-9 part, Aspongopus 5-12 part, Radix Paeoniae Alba 10-15 part, Fructus Alpiniae Oxyphyllae 3-9 part, Cortex Cinnamomi 5-12 part, Rhizoma Corydalis (processed with vinegar) 2-5 part, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 3-6 part;
Component two: Rhizoma Atractylodis 10-15 part, Rhizoma Alpiniae Officinarum 10-15 part, Rhizoma Cyperi 6-12 part, Fructus Polygoni Orientalis 15-30 part, Fructus Hordei Germinatus 5-10 part, Fructus Chaenomelis 10-15 part, Fructus Amomi Rotundus 6-10 part, Radix Bupleuri 6-12 part, Endothelium Corneum Gigeriae Galli 10-15 part.
Preferably, a kind of Chinese medicine composition for the treatment of chronic gastritis, comprises the crude drug of following component by weight:
Component one: Caulis Perillae 8 parts, Fructus Citri Sarcodactylis 8 parts, Fructus Amomi 10 parts, Pericarpium Citri Reticulatae 8 parts, Fructus Toosendan 6 parts, Aspongopus 8 parts, the Radix Paeoniae Alba 12 parts, Fructus Alpiniae Oxyphyllae 6 parts, Cortex Cinnamomi 10 parts, Rhizoma Corydalis (processed with vinegar) 4 parts, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 4 parts;
Component two: Rhizoma Atractylodis 12 parts, Rhizoma Alpiniae Officinarum 12 parts, Rhizoma Cyperi 10 parts, Fructus Polygoni Orientalis 25 parts, Fructus Hordei Germinatus 8 parts, Fructus Chaenomelis 12 parts, 8 parts, Fructus Amomi Rotundus, Radix Bupleuri 10 parts, Endothelium Corneum Gigeriae Galli 12 parts.
Described component one makes oral medicine: take each component by recipe quantity, all the other all medicines except Rhizoma Corydalis (processed with vinegar), with the distilled water immersion 0.5-1 hour of 8 pieces, Fructus Jujubae and 3 times amount, decocts twice, each 30 minutes, merges decoction liquor and obtains medicine juice; Rhizoma Corydalis (processed with vinegar) is ground into powder rear medicine juice to take after mixing it with water.Every day, potion, took at twice.
Described component two makes acupoint plaster, preparation method is: by all taste Chinese medicine of component two, extract with the ethanol of 80%, ethanol consumption is that (ethanol divides three times and adds, and addition is respectively 10 times of medical material for 24 times of medical material amount, 7 times, 7 times), reflux, extract, 3 times, (three extraction times are respectively 1.5h to extract total time 180min, 1h, 0.5h).Extracting solution is at 65 DEG C, and-0.08MPa concentrating under reduced pressure, reclaims ethanol, be concentrated into the thick paste that relative density is 1.5, and by gained thick paste at 60 DEG C, drying under reduced pressure 8h under-0.08MPa, namely obtains drug extract powder after crossing 60 mesh sieves.Extract powder is put in mortar, adds lanoline and grind well, then add Mel and mix well, get 5-8 gram plaster mounted be applied to 3 centimeter square kraft paper or cotton on acupoint plaster.Stick after used time routine disinfection on tsu san li (two), ZHONGWAN acupoint, fix with medical proof fabric.Within 3-5 days, change once, within 30 days, be a course for the treatment of.
Chronic erosive gastritis is Digestive System Department commonly encountered diseases, frequently-occurring disease, is subordinate to the traditional Chinese medical science " gastric abscess ", " feeling of fullness " category.Clinically, gastritis sufferer often there will be in vague epigastralgia feeling of distension and oppression, stomach symptoms such as having burn feeling, belch are frequent, acid regurgitation, halitosis.Can find that the gastric mucosa of this patient there will be the situations such as hyperemia, swelling or erosion when doing gastroscopy.Can atrophy be there is in its gastric mucosa of this patient that the course of disease is longer, and with intestinalization raw (or Intestinal metaplasia, or large intestineization is raw).Medical research confirms, causes the root of gastritis to be that helicobacter pylori (hp) infects.But many gastritis sufferers are after antibacterial therapy, and the helicobacter pylori in its body transfers feminine gender to by the positive, the symptom such as flatulence, belch, regurgitation, greasy fur on tongue still can exist or repeatedly occur.This is mostly caused by warm clear, the disorder of stomach-QI in patient body.The present inventor thinks, " WEIDE fall then and ", " all vomitings acid, all belongs to heat ", therefore treats the principle that the common disease such as belch, acid regurgitation of gastritis should adhere to clearing away heat and eliminating dampness, regulating QI and lowering the adverseness.In component one, Fructus Citri Sarcodactylis liver-smoothing, qi-regulating, stomach function regulating reduce phlegm; Fructus Amomi removing dampness is whetted the appetite, and warming the spleen is regulated the flow of vital energy; Caulis Perillae regulating the flow of QI to ease the stomach, is all the main regulating the stomach to normalize QI of monarch drug.Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Fructus Toosendan soothing liver-QI promoting the circulation of QI to relieve pain; The pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating is all the main spleen invigorating pain relieving of ministerial drug.Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins; Aspongopus regulating QI to relieve pain, warming middle-JIAO is supporing yang; It is supporing yang that Cortex Cinnamomi mends fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow; Be all adjuvant drug, there is effect of supporing yang warming the meridian, sending down the abnormal ascending QI cold expelling.Rhizoma Corydalis is invigorated blood circulation, promoting the circulation of QI, pain relieving; Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication altogether for making medicine, removing dampness invigorate blood circulation promoting the circulation of QI removing toxic substances.Above-mentioned compatibility has depressed liver-energy dispersing and QI regulating, and stomach and alleviating pain, the effects such as invigorating the spleen for eliminating dampness; at adjustment gastrointestinal function; while eliminating mucosal inflammation, also there is protection gastric mucosa, strengthen the effect of gastric mucosa resistance against diseases; can effectively improve and eliminate epigastric distending pain; be off one's feed, have the hiccups, gas is toward up; pantothenic acid, the symptoms such as burn feeling.
The present invention adopts the method treatment combined with external application for oral administration, and external point-application, embodies the thought of the traditional Chinese medical science " inner disease outer treat ", is one of traditional Chinese medical science traditional remedies, has the dual clinical treatment effect of acupoint stimulation and drug absorption.By to the stimulation at acupuncture point and adjustment, effective ingredient is made to enter space between skin and muscles from pore, dredge the meridian passage " be cut in skin, thorough in meat, take in air-breathing, incorporate sepage ", bring out the best in each other with oral medicine.
Clear Xu Dachun was once said: " decoction deficiency is to the greatest extent sick ... ... with plaster it, its gas inaccessible, makes the property of medicine enter its space between skin and muscles from pore, dredge the meridian passage, or carries it, or attack and loose it, comparatively take medicine particularly strong ".Stick medicine and directly act on body surface point or surperficial focus, make local vascular dilation, blood circulation accelerates, and plays blood circulation promoting and blood stasis dispelling, heat clearing away is drawn out pus by applying a plaster to the affected part, reducing swelling and alleviating pain, hemostasia and promoting granulation, antiinflammatory evacuation of pus, improve the effect of surrounding tissue nutrition.Also can make agent permeates therethrough fur space between skin and muscles going from the exterior into the interior, by the through operation of meridians, contact internal organs, link up the exterior and the interior, play stronger drug action.Sayed as " Li Yue Pianwen, Rhymed Discourse for Topical Remedies ": " be cut in skin, thorough in meat, take in air-breathing, incorporate sepage ".And with its medication, can eliminating evil, gas of drawing out pus by applying a plaster to the affected part to go out, clear within pressing down pathogen; Energy righting, Tong Yingwei, increases and falls, reason negative and positive, settling five organs; The gas that energy setback five is strongly fragrant, and money source.
Point application therapy is by the direct stimulating acupoint of medicine, and pass through Transdermal absorption, make local drug concentration apparently higher than other positions, act on comparatively direct, its indication is throughout clinical departments, " can walk abreast with treatment by oral administration of medicines, and can mend the too late for the treatment of by oral administration of medicines ", often can obtain beyond thought remarkable efficacy to many severe and lingering illness obstinate diseases.Acupoint plaster of the present invention Rhizoma Alpiniae Officinarum warming stomach for dispelling cold used, help digestion pain relieving; Rhizoma Cyperi promoting QI circulation for relieving depression, menstruction regulating and pain relieving; Fructus Polygoni Orientalis falls apart blood eliminating mass, removing food stagnancy pain relieving; Fructus Hordei Germinatus promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite; Fructus Chaenomelis suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness; Fructus Amomi Rotundus removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.Radix Bupleuri reconciling superficies and interior, soothing the liver, yang invigorating; Endothelium Corneum Gigeriae Galli reconciling superficies and interior, soothing the liver, yang invigorating.All medicines share effects such as having warming stomach for dispelling cold, invigorating the spleen and regulating the stomach, promoting flow of QI and blood.After the process such as each medicinal material extract cream, effective ingredient is easier to through skin, stimulating acupoint, follows through entering stomach, and medicine absorbs through skin, alleviates the intestines and stomach burden, and to patient without any misery, and curative effect is lasting.
Acupoint plaster of the present invention chooses the tsusanli acupoint, ZHONGWAN acupoint, and without gastro-intestinal administration, the fraud of not damaged taste, controls and do not commit, and controls the inferior and does not go against one's superiors, and does not go against one's superiors down in controlling.The tsusanli acupoint, is one of the main acupuncture point of " stomach channel of foot-Yang-ming ", is positioned at little leg outer side, lower 3 cun of Dubi, and on Dubi and Opened Hollow line, shallow-layer is furnished with lateral sural cutaneous nerve.Deep layer has the branch of artery and vein before shin or to belong to.Cure mainly gastrointestinal disease, lower limb flaccidity syndrome and arthralgia syndrome, mental diseases, surgical disease, all cards of asthenia.Dryization spleen wets, hair growth promoting gastric qi.ZHONGWAN acupoint, belongs to the conception vessel of eight extra-channel.The disease that cures mainly in this cave is: digestive system disease, as abdominal distention, diarrhoea, stomachache, borborygmus, acid regurgitation, vomiting, constipation, jaundice etc., in addition to general gastropathy, inappetence, dizzy, tinnitus, comedo, energy is not good, neurasthenia is also very effective.This acupuncture point is one of main acupoint on human body conception vessel, treatment is felt sick, it is heartburn to treat, belch, treatment chronic hepatitis, treatment chronic gastritis, stomachache etc.
Oral medicine acts on human body main manifestations in conjunction with point-application and goes out a kind of comprehensive function, existing oral drugs go directly the curative effect of the intestines and stomach, there is again medicine to the effect of the stimulation bound drug at acupuncture point itself, and influence each other, interact and mutually supplement between two kinds for the treatment of factors, the common entirety superposition therapeutical effect played.Medicine is for oral administration to be adjusted local QI and blood with its warm stimulation of external application, and the warm effect coordinating Herbal medicines for external use to necessarily increase medicine that stimulates, the Chinese medicine of the pungent taste of many tools is easy to especially absorb in thermal environment, thereby enhances the effect of medicine.Herbal medicines for external use then have stimulated acupuncture point itself on acupuncture point, excites through gas, has transferred the function of passages through which vital energy circulates, makes it the mass action having played qi and blood circulation promotion, battalion's negative and positive better.
The pharmacological action of each component is as follows:
Caulis Perillae: pungent, temperature.Return lung, spleen channel.Regulating the flow of QI to ease the stomach, pain relieving, antiabortive.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch is vomitted, frequent fetal movement.
Fructus Citri Sarcodactylis: pungent; Bitter; Temperature; Liver; Stomach; Spleen; Lung meridian; Liver-smoothing, qi-regulating; Stomach function regulating reduces phlegm.Hypochondriac pain, the breast of main depression of liver-QI are vexed; The abdominal distention of incoordination between the liver and stomach, stagnation of QI in spleen and stomach, heating installation, to feel sick; Chronic cough abundant expectoration.
Fructus Amomi: pungent, temperature.Return spleen, stomach, kidney channel.Removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Pericarpium Citri Reticulatae: bitter, pungent, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Fructus Toosendan: bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Ramulus Cinnamomi: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Aspongopus: salty, temperature.Return liver,spleen,kidney warp.Regulating QI to relieve pain, warming middle-JIAO is supporing yang.For cold syndrome of the stomach distending pain, stomachache due to hyperactive liver-QI attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.
The Radix Paeoniae Alba: bitter, sour, is slightly cold.Return liver, spleen channel.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Fructus Alpiniae Oxyphyllae: acrid in the mouth; Spleen warm in nature; Kidney channel is warming spleen and stopping diarrha takes the photograph saliva; Warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Main Deficiency and coldness of spleen and stomach; Vomiting; Have loose bowels; Coldly in abdomen to educate; The many salivas of mouth; Enuresis due to deficiency of the kidney; Frequent micturition; Seminal emission; Nebulousurine
Cortex Cinnamomi: pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.
Rhizoma Atractylodis: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Rhizoma Alpiniae Officinarum: pungent, heat.Return spleen, stomach warp.Warming stomach for dispelling cold, help digestion pain relieving.For coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.
Rhizoma Cyperi: pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Fructus Polygoni Orientalis: salty, is slightly cold.Return liver, stomach warp.Loose blood eliminating mass, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, goiter swells and ache, and food stagnation does not disappear, epigastric distending pain.
Fructus Hordei Germinatus: sweet is flat.Return spleen, stomach warp.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.Fructus Hordei Germinatus: invigorating the spleen and regulating the stomach, soothing the liver circulation of qi promoting.For insufficiency of the spleen lack of appetite, milk smoulders.
Fructus Chaenomelis: acid, temperature.Return liver, spleen channel.Suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness.For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, convulsion of vomiting and diarrhoea, beriberi edema.
Fructus Amomi Rotundus: pungent, temperature.Return lung, spleen, stomach warp.Removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Endothelium Corneum Gigeriae Galli: bitter, is slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The present invention has following beneficial effect:
1, the present invention's method treatment of adopting for oral administration and external application to combine, oral medicine used, stomach warming nourishing the stomach, QI invigorating consolidates, and at adjustment gastrointestinal function, while eliminating mucosal inflammation, also has protection gastric mucosa, strengthens the effect of gastric mucosa resistance against diseases.External point-application, embodies the thought of the traditional Chinese medical science " inner disease outer treat ", is one of traditional Chinese medical science traditional remedies, has the dual clinical treatment effect of acupoint stimulation and drug absorption.By to the stimulation at acupuncture point and adjustment, effective ingredient is made to enter space between skin and muscles from pore, dredge the meridian passage " be cut in skin, thorough in meat, take in air-breathing, incorporate sepage ", bring out the best in each other with oral medicine.Selected medicine warming stomach for dispelling cold, invigorating the spleen and regulating the stomach, promoting flow of QI and blood, after extracting the process such as cream processed, be easy to through skin, stimulating acupoint, follow through entering stomach, medicine absorbs through skin, without the need to taking a large amount of Chinese medicine, alleviate the intestines and stomach burden, to patient without any misery, and curative effect is lasting.
2, cure rate of the present invention is high, as long as and more after be careful in one's diet a little, can not recur.Totall effective rate in clinical treatment is 98.1%.
Below in conjunction with clinical treatment situation, further illustrate curative effect of the present invention.
1 data and method
1.1 physical data
Select chronic erosive gastritis patient 108 example that my institute in April, 2013 ~ 2014 are accepted for medical treatment year June, all patients all confirm through fibergastroscope or pathology, meet the standard of Ministry of Public Health " the pathological diagnosis standard of chronic gastritis and classification ", get rid of taste-blindness rate patient, and routine blood test, routine urinalysis, liver function, renal function, electrocardiographic abnormality and pregnant patient.Observation group and matched group is divided into, observation group 54 example, man 34 example, female 20 example, 19 ~ 52 years old age, 33.2 years old mean age, the course of disease 1 ~ 12 year, average course of disease 7.8 years according to principle that is random, contrast; Matched group 54 example, man 33 example, female 21 example, 18 ~ 51 years old age, 33.5 years old mean age, the course of disease 1 ~ 13 year, average course of disease 8.1 years.Two groups of the physical data comparison in difference not statistically significant such as Gender, ages (P>0.05).
1.2 method
Two groups of patient procedure are 4 weeks, and observation group adopts Chinese medicine composition of the present invention---and oral medicine is treated in conjunction with acupoint plaster: oral medicine potion every day, takes at twice; Acupoint plaster sticks on tsu san li (two), ZHONGWAN acupoint, within 3-5 days, changes once, within 30 days, is a course for the treatment of.
Matched group is oral omeprazole enteric-coated capsules 20mg then, every day 2 times, bismuth aluminate compound 2, every day 3 times.Observe and compare the clinical therapeutic efficacy of two groups of patients.
1.3 Judging index adopt the treatment standard of Ministry of Public Health " the pathological diagnosis standard of chronic gastritis and classification ": 1. cure: symptom all disappears, and gastroscopy recovers normal; 2. effective: remission, gastroscopy takes a turn for the better more than 2/3; 3. effective: symptom alleviates, or gastroscopy gastric mucosal lesions range shorter more than 1/2; 4. invalid: clinical symptoms is without improvement or increase the weight of, or gastroscopy is unchanged.Effectively total=to cure+effective+effectively.
1.4 statistical procedures adopt SPSS13.0 statistical software to carry out data analysis, and enumeration data % formation represents, adopt x2 inspection, P<0.05 is that difference has statistical significance.
2 results
Observation group's totall effective rate in clinical treatment is 98.1%, and matched group totall effective rate in clinical treatment is 75.9%, two groups and compares, and observation group's therapeutic effect is obviously better than matched group, and difference has statistical significance (P<0.05).In table 1.
The comparison (n, %) of table 1 liang group patient clinical therapeutic effect
| Group | n | Cure | Effective | Effectively | Invalid | Effectively total |
| Observation group | 54 | 18 | 26 | 9 | 1 | 53(98.1％) |
| Matched group | 54 | 8 | 22 | 11 | 13 | 41(75.9％) |
3 discuss
Chronic erosive gastritis is a kind of commonly encountered diseases, frequently-occurring disease, has recurrent exerbation, a feature that touching difficulty heals.Be subordinate to the traditional Chinese medical science " gastric abscess ", " feeling of fullness " category., Traditional Chinese Medicine thinks that its cause of disease and cold-evil, food stagnation, stagnation of QI due to depression of the liver, weakness of the spleen and stomach etc. are closely related.Treatment by Chinese herbs of the present invention, based on warming middle-Jiao and tonifying deficiency, regulating QI to relieve pain, is held concurrently with pathogenic heat, putrefaction-removing granulation-promoting in clearing away heat and eliminating dampness, blood circulation promoting and blood stasis dispelling, invigorating the spleen and benefiting QI, stopping nausea and vomiting by lowering the adverse flow of QI, removing obstruction for relieving pain, clearing stomach.Oral medicine, at adjustment gastrointestinal function, while eliminating mucosal inflammation, also has protection gastric mucosa, strengthens the effect of gastric mucosa resistance against diseases.Acupoint plaster adopts modern Chinese medicine extraction process to extract the effective ingredient of medicine, and medicine penetrance is good, ensure that medicine can abundant Transdermal absorption play curative effect, has depressed liver-energy dispersing and QI regulating, and stomach and alleviating pain, the effects such as invigorating the spleen for eliminating dampness.Both combine and can effectively improve and eliminate epigastric distending pain, are off one's feed, have the hiccups, gas is toward up, pantothenic acid, the symptoms such as burn feeling, Be very effective, gastrointestinal motility is had to the effect of dual regulation and anti-inflammatory and choleretic, the disorder of gastric electrical activity basic electrical rhythm under stress state can be regulated, suppress hypercontractility and Acid Secretion, have remarkable facilitation to contractile motion at the bottom of stomach, moreover, Chinese medicine of the present invention also has antiulcer effect.
Model case 1: patient Lee, man, 42 years old, first visit in August, 2013, main suit's epigastrium pain and distension, to attach most importance to, with belch, poor appetite, asthenia at nightfall.Take western medicines in treatment repeatly, bad during symptom fashion.Head examines: disease, as front, with xerostomia, tastelessness, become thin, lost weight.Light red tongue color is dark, and white and thin fur Tianjin is few, weak pulse.Gastroscopy result is diagnosed as chronic erosive gastritis.Give traditional Chinese medicine composition for treating of the present invention, after 14 days, symptom is clearly better, and after one month, above-mentioned symptom disappears, and distending pain takes a turn for the better without, appetite, and tongue profit normal pulse, all diseases are eliminated.Gastroscopy stomach lining inflammation is clearly better.Follow up a case by regular visits to 6 months without recurrence.
Model case 2: patient Wang, man, 54 years old.Patient has a stomachache more than 5 years, and period stomachache recurrent exerbation, once took Western medicine as acid suppression medicines such as omeprazoles, curative effect does not show.Symptom work again after drug withdrawal.Time to our hospital: have a dull ache in stomach, companion's gastral cavity is swollen, and belch, increases the weight of after meal, pantothenic acid, heartburn sense, epigastric upset, and morning plays dry mouth with bitter taste, weak, and two just still adjust, and tongue is partially red, yellow and thin fur, thready pulse.Gastroscopy shows: gastric antrum portion variola sample is rotten to the corn.Use Drug therapy of the present invention, oral medicine potion on the one, takes at twice, and acupoint plaster sticks on tsu san li (two), ZHONGWAN acupoint, within 3-5 days, changes once.After 7 days, pantothenic acid is alleviated, and stomachache alleviates, and tongue arteries and veins is the same.Following the service is pantothenic acid not work after 14 days, and flatulence, belch disappear substantially, and stomachache is eliminated.After one month, all diseases disappear.Take continuously after 3 months and check gastroscope display, rotten to the corn disappearance.
Detailed description of the invention
Embodiment 1. 1 kinds treats the Chinese medicine composition of chronic gastritis, comprises the crude drug of following component:
Component one: Caulis Perillae 5 grams, Fructus Citri Sarcodactylis 5 grams, Fructus Amomi 6 grams, Pericarpium Citri Reticulatae 5 grams, Fructus Toosendan 4 grams, Aspongopus 5 grams, the Radix Paeoniae Alba 10 grams, Fructus Alpiniae Oxyphyllae 3 grams, Cortex Cinnamomi 5 grams, Rhizoma Corydalis (processed with vinegar) 2 grams, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 3 grams;
Component two: Rhizoma Atractylodis 15 grams, Rhizoma Alpiniae Officinarum 15 grams, Rhizoma Cyperi 12 grams, Fructus Polygoni Orientalis 30 grams, Fructus Hordei Germinatus 10 grams, Fructus Chaenomelis 15 grams, 10 grams, Fructus Amomi Rotundus, Radix Bupleuri 12 grams, Endothelium Corneum Gigeriae Galli 15 grams.
Described component one makes oral medicine: take each component by recipe quantity, all the other all medicines except Rhizoma Corydalis (processed with vinegar), with the distilled water immersion 0.5-1 hour of 8 pieces, Fructus Jujubae and 3 times amount, decocts twice, each 30 minutes, merges decoction liquor and obtains medicine juice; Rhizoma Corydalis (processed with vinegar) is ground into powder rear medicine juice to take after mixing it with water.Every day, potion, took at twice.
Described component two makes acupoint plaster, preparation method is: by all taste Chinese medicine of component two, extract with the ethanol of 80%, and ethanol consumption is 24 times (10:7:7) of medical material amount, reflux, extract, 3 times, extracts total time 180min (1.5h:1h:0.5h).Extracting solution is at 65 DEG C, and-0.08MPa concentrating under reduced pressure, reclaims ethanol, be concentrated into the thick paste that relative density is 1.5, and by gained thick paste at 60 DEG C, drying under reduced pressure 8h under-0.08MPa, namely obtains drug extract powder after crossing 60 mesh sieves.Extract powder is put in mortar, adds lanoline and grind well, then add Mel and mix well, get 5-8 gram plaster mounted be applied to 3 centimeter square kraft paper or cotton on acupoint plaster.Stick after used time routine disinfection on tsu san li (two), ZHONGWAN acupoint, fix with medical proof fabric.Within 3-5 days, change once, within 30 days, be a course for the treatment of.
Embodiment 2. 1 kinds treats the Chinese medicine composition of chronic gastritis, comprises the crude drug of following component:
Component one: Caulis Perillae 10 grams, Fructus Citri Sarcodactylis 10 grams, Fructus Amomi 12 grams, Pericarpium Citri Reticulatae 10 grams, Fructus Toosendan 9 grams, Aspongopus 12 grams, the Radix Paeoniae Alba 15 grams, Fructus Alpiniae Oxyphyllae 9 grams, Cortex Cinnamomi 12 grams, Rhizoma Corydalis (processed with vinegar) 5 grams, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 6 grams;
Component two: Rhizoma Atractylodis 15 grams, Rhizoma Alpiniae Officinarum 15 grams, Rhizoma Cyperi 12 grams, Fructus Polygoni Orientalis 30 grams, Fructus Hordei Germinatus 10 grams, Fructus Chaenomelis 15 grams, 10 grams, Fructus Amomi Rotundus, Radix Bupleuri 12 grams, Endothelium Corneum Gigeriae Galli 15 grams.
Preparation and instructions of taking are with embodiment one.
Embodiment 3. 1 kinds treats the Chinese medicine composition of chronic gastritis, comprises the crude drug of following component:
Component one: Caulis Perillae 8 grams, Fructus Citri Sarcodactylis 8 grams, Fructus Amomi 10 grams, Pericarpium Citri Reticulatae 8 grams, Fructus Toosendan 6 grams, Aspongopus 8 grams, the Radix Paeoniae Alba 12 grams, Fructus Alpiniae Oxyphyllae 6 grams, Cortex Cinnamomi 10 grams, Rhizoma Corydalis (processed with vinegar) 4 grams, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 4 grams;
Component two: Rhizoma Atractylodis 12 grams, Rhizoma Alpiniae Officinarum 12 grams, Rhizoma Cyperi 10 grams, Fructus Polygoni Orientalis 25 grams, Fructus Hordei Germinatus 8 grams, Fructus Chaenomelis 12 grams, 8 grams, Fructus Amomi Rotundus, Radix Bupleuri 10 grams, Endothelium Corneum Gigeriae Galli 12 grams.
Preparation and instructions of taking are with embodiment one.
Embodiment 4. 1 kinds treats the Chinese medicine composition of chronic gastritis, comprises the crude drug of following component:
Component one: Caulis Perillae 9 grams, Fructus Citri Sarcodactylis 7 grams, Fructus Amomi 8 grams, Pericarpium Citri Reticulatae 6 grams, Fructus Toosendan 7 grams, Aspongopus 10 grams, the Radix Paeoniae Alba 10 grams, Fructus Alpiniae Oxyphyllae 7 grams, Cortex Cinnamomi 11 grams, Rhizoma Corydalis (processed with vinegar) 4 grams, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 4 grams;
Component two: Rhizoma Atractylodis 13 grams, Rhizoma Alpiniae Officinarum 14 grams, Rhizoma Cyperi 11 grams, Fructus Polygoni Orientalis 20 grams, Fructus Hordei Germinatus 7 grams, Fructus Chaenomelis 11 grams, 7 grams, Fructus Amomi Rotundus, Radix Bupleuri 7 grams, Endothelium Corneum Gigeriae Galli 12 grams.
Preparation and instructions of taking are with embodiment one.
Claims (4)
1. treat a Chinese medicine composition for chronic gastritis, it is characterized in that, comprise the crude drug of following component by weight:
Component one: Caulis Perillae 5-10 part, Fructus Citri Sarcodactylis 5-10 part, Fructus Amomi 6-12 part, Pericarpium Citri Reticulatae 5-10 part, Fructus Toosendan 4-9 part, Aspongopus 5-12 part, Radix Paeoniae Alba 10-15 part, Fructus Alpiniae Oxyphyllae 3-9 part, Cortex Cinnamomi 5-12 part, Rhizoma Corydalis (processed with vinegar) 2-5 part, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 3-6 part;
Component two: Rhizoma Atractylodis 10-15 part, Rhizoma Alpiniae Officinarum 10-15 part, Rhizoma Cyperi 6-12 part, Fructus Polygoni Orientalis 15-30 part, Fructus Hordei Germinatus 5-10 part, Fructus Chaenomelis 10-15 part, Fructus Amomi Rotundus 6-10 part, Radix Bupleuri 6-12 part, Endothelium Corneum Gigeriae Galli 10-15 part.
2. the Chinese medicine composition of described treatment chronic gastritis as claimed in claim 1, is characterized in that, comprise the crude drug of following component by weight:
Component one: Caulis Perillae 8 parts, Fructus Citri Sarcodactylis 8 parts, Fructus Amomi 10 parts, Pericarpium Citri Reticulatae 8 parts, Fructus Toosendan 6 parts, Aspongopus 8 parts, the Radix Paeoniae Alba 12 parts, Fructus Alpiniae Oxyphyllae 6 parts, Cortex Cinnamomi 10 parts, Rhizoma Corydalis (processed with vinegar) 4 parts, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 4 parts;
Component two: Rhizoma Atractylodis 12 parts, Rhizoma Alpiniae Officinarum 12 parts, Rhizoma Cyperi 10 parts, Fructus Polygoni Orientalis 25 parts, Fructus Hordei Germinatus 8 parts, Fructus Chaenomelis 12 parts, 8 parts, Fructus Amomi Rotundus, Radix Bupleuri 10 parts, Endothelium Corneum Gigeriae Galli 12 parts.
3. the Chinese medicine composition of described treatment chronic gastritis as claimed in claim 1, it is characterized in that, described component one makes oral medicine: take each component by recipe quantity, all the other all medicines except Rhizoma Corydalis (processed with vinegar), with the distilled water immersion 0.5-1 hour of 8 pieces, Fructus Jujubae and 3 times amount, decoct twice, each 30 minutes, merge decoction liquor and obtain medicine juice; Rhizoma Corydalis (processed with vinegar) is ground into powder rear medicine juice to take after mixing it with water.
4. the Chinese medicine composition of described treatment chronic gastritis as claimed in claim 1, it is characterized in that, described component two makes acupoint plaster, preparation method is: by all taste Chinese medicine of component two, extract with the ethanol of 80%, ethanol consumption is 24 times of medical material amount, reflux, extract, 3 times, extracts total time 180min; Extracting solution is at 65 DEG C, and-0.08MPa concentrating under reduced pressure, reclaims ethanol, be concentrated into the thick paste that relative density is 1.5, and by gained thick paste at 60 DEG C, drying under reduced pressure 8h under-0.08MPa, namely obtains drug extract powder after crossing 60 mesh sieves; Extract powder is put in mortar, adds lanoline and grind well, then add Mel and mix well, get 5-8 gram plaster mounted be applied to 3 centimeter square kraft paper or cotton on acupoint plaster.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107029170A (en) * | 2017-06-20 | 2017-08-11 | 朱彩玲 | A kind of medicament and its processing technology for chronic gastritis |
| CN110279719A (en) * | 2019-06-27 | 2019-09-27 | 北京市房山区中医医院 | It treats and presses packet and its preparation and application outside the late silkworm excrement of diabetic gastroparesis |
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| CN101041050A (en) * | 2007-04-20 | 2007-09-26 | 王伟 | Chinese traditional medicine compound took orally for treating chronic gastritis |
| CN102670909A (en) * | 2012-05-03 | 2012-09-19 | 成都绿迪科技有限公司 | Formula of Chinese medicine for treating chronic gastritis |
| CN102861298A (en) * | 2012-10-18 | 2013-01-09 | 林强 | Traditional Chinese medicine composition for treating chronic gastritis |
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| CN102670909A (en) * | 2012-05-03 | 2012-09-19 | 成都绿迪科技有限公司 | Formula of Chinese medicine for treating chronic gastritis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029170A (en) * | 2017-06-20 | 2017-08-11 | 朱彩玲 | A kind of medicament and its processing technology for chronic gastritis |
| CN110279719A (en) * | 2019-06-27 | 2019-09-27 | 北京市房山区中医医院 | It treats and presses packet and its preparation and application outside the late silkworm excrement of diabetic gastroparesis |
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