CN102895392B - Chinese medicine for treating duodenal ulcer - Google Patents

Chinese medicine for treating duodenal ulcer Download PDF

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CN102895392B
CN102895392B CN2012104397459A CN201210439745A CN102895392B CN 102895392 B CN102895392 B CN 102895392B CN 2012104397459 A CN2012104397459 A CN 2012104397459A CN 201210439745 A CN201210439745 A CN 201210439745A CN 102895392 B CN102895392 B CN 102895392B
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radix
parts
chinese medicine
duodenal ulcer
ulcer
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CN102895392A (en
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李升玲
徐连江
于慧玲
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李升玲
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Abstract

The invention discloses a Chinese medicine for treating duodenal ulcer. The Chinese medicine is prepared from codonopsis pilosula, cudrania cochinchinensis, curious kadsura root stem, common nepenthes, lousewort root, maitake, Chinese magnoliavine fruit, Mongolian snake gourd root, buckbean and liquorice. The Chinese medicine can be clinically used for treating duodenal ulcer.

Description

A kind of Chinese medicine for the treatment of duodenal ulcer
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of duodenal ulcer.
Background technology
Duodenal ulcer is commonly encountered diseases, frequently-occurring disease clinically, has outbreak tendency repeatedly.Treated duodenal ulcer single western medicine therapy commonly used, doctor trained in Western medicine is taked antiulcer and the same use of anti helicobacter pylori medicine, or adopts low dose of H after ulcer healing in the past 2Receptor antagonist maintains treatment and reduces relapse rate, but the unavoidable side effect of long-term taking, but effect is not satisfactory draws through inventor's long-term practice, and Chinese medicine is controlled duodenal ulcer and had better effect, obtains good effect.
Summary of the invention
The Chinese medicine of the treatment duodenal ulcer that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Codonopsis, Radix Cudraniae, Radix seu Caulis Kadsurae Heteroclitae, Herba nepenthis, Radix Pedicularis Henryi, Grifola frondosa, Fructus Schisandrae Chinensis, Radix Trichosanthis, Herba menyanthis, Radix Glycyrrhizae according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention and made by following raw material medicaments, Radix Codonopsis 40-60 part, Radix Cudraniae 40-60 part, Radix seu Caulis Kadsurae Heteroclitae 30-50 part, Herba nepenthis 30-50 part, Radix Pedicularis Henryi 20-40 part, Grifola frondosa 20-40 part, Fructus Schisandrae Chinensis 20-40 part, Radix Trichosanthis 10-30 part, Herba menyanthis 10-30 part, Radix Glycyrrhizae 10-20 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: 50 parts of Radix Codonopsis, 50 parts of Radix Cudraniaes, 40 parts of Radix seu Caulis Kadsurae Heteroclitae, 40 parts of Herba nepenthiss, 30 parts of Radix Pedicularis Henryis, 30 parts of Grifola frondosa, 30 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Trichosanthis, 20 parts of Herba menyanthiss, 15 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.QI invigorating, promote the production of body fluid, nourish blood.For the empty asthenia of the body of deficiency of QI in middle-JIAO, the cough tachypnea of lung qi virtual loss, breathing hard of gas Tianjin two wounds is thirsty, dizzy cardiopalmus etc.
Radix Cudraniae: light, bitter, cool.Dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling.Cure mainly rheumatic arthralgia, traumatic injury, parotitis, amenorrhea, furuncle carbuncle, the diseases such as duodenal ulcer.
Radix seu Caulis Kadsurae Heteroclitae: acrid, bitter, warm.Return spleen, stomach, Liver Channel.Expelling wind and removing dampness, promoting the circulation of QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatic arthralgia, stomachache, stomachache, dysmenorrhea, puerperal abdonimal pain, duodenal ulcer, traumatic injury, chronic lambago and skelalgia etc.
Herba nepenthis: sweet, light, cool.Return lung, gallbladder, stomach warp.Nourishing the lung to arrest cough, clearing away heat-damp and promoting diuresis calculus, removing toxic substances and promoting subsidence of swelling.Clinical in dryness of the lung hemoptysis, cold cough, pertussis, jaundice, dysentery, lithangiuria, also can be used for gastric and duodenal ulcers, hypertension, diabetes, the diseases such as skin infection carbuncle.
Radix Pedicularis Henryi: sweet, micro-hardship, temperature.Fill blood, bone and muscle strengthening, strengthening the spleen and stomach.For dizziness and tinnitus, palpitation and short breath, brothers' flaccidity is soft, bones and muscles pain, bronchitis, food stagnation of child, malnutrition.
Grifola frondosa: sweet, flat.Replenishing QI to invigorate the spleen, tonify deficiency righting.For deficiency of the spleen causing weakness of QI, fatigue and asthenia, spiritlessness and sparing of words; Diet reduces, abdominal distention after meal; The person that has the above-mentioned symptom after tumor patient radiotherapy or chemotherapy.
Fructus Schisandrae Chinensis: sour, warm.Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, mind tranquilizing and the heart calming.Cure mainly the cough dyspnea due to deficiency, emission, urinate the quite enuresis, incessant chronic diarrhea, and spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia etc.
Radix Trichosanthis: sweet, micro-hardship, be slightly cold, attach to the lung and stomach meridians.Clearing away heat and promoting production of body fluid, clearing away lung-heat and moistening for dryness, removing toxicity for eliminating carbuncles.Cure mainly calentura thirsty, the polydipsia of quenching one's thirst, carbuncle skin infection.
Herba menyanthis: sweet, micro-hardship, cold in nature.GUIXIN, spleen channel.Strengthening the spleen to promote digestion, tranquilizing by nourishing the heart, clearing away heat and promoting diuresis.Clinical in gastritis, dyspepsia, palpitation and insomnia, jaundice due to damp-heat, cholecystitis, edema, dysuria or fervid puckery pain.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Duodenal ulcer belongs to the traditional Chinese medical science " gastric abscess " category more.Clinical common with deficiency syndrome or simulataneous insufficiency and excessive.The cause of disease mostly is eating and drinking without temperance, disorder of emotion, overstrain internal injury equivalent damage taste, causes weakness of the spleen and stomach, dysfunction of the spleen in transportation and transformation, or folder is wet, folder heat, or prolonged illness causes the stasis of blood, therefore the methods such as soothing liver and strengthening spleen, regulating QI to relieve pain, blood stasis dispelling removing dampness, heat clearing away are the method for primary disease treatment.In the present invention, Radix Codonopsis has the effect of supplementing QI for promoting the production of body fluid, is monarch drug, and Radix Cudraniae, Radix seu Caulis Kadsurae Heteroclitae heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, be ministerial drug, the Herba nepenthis heat-clearing and toxic substances removing, Radix Pedicularis Henryi, Grifola frondosa, Herba menyanthis replenishing QI to invigorate the spleen, Fructus Schisandrae Chinensis, Radix Trichosanthis convergence astringing intestine to stop diarrhea, and stomach and alleviating pain, clearing away heat and promoting production of body fluid, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Through clinical practice, find that duodenal ulcer is had to unique curative effect, all medicines are played the effect of heat-clearing and toxic substances removing, convergence astringing intestine to stop diarrhea, invigorating the spleen and benefiting QI altogether, reach the purpose for the treatment of duodenal ulcer.
Chinese medicine of the present invention was in 2009 to 2011 the routine patients of clinical observation duodenal ulcer 55, and clinical report is as follows:
1, physical data
In 55 routine patients, age 18-65 year, the course of disease is many at 3 months to 8 years, 45 years old mean age.
2, diagnostic criteria
2.1 diagnosis basis Ministry of Public Health " guideline of clinical investigations of new Chinese medicine treatment peptic ulcer ":
(1) periodicity of prolonged and repeated outbreak, the chronic epigastrium pain of rhythmicity; (2) epigastrium has limitation deeply in tenderness; (3) the x-ray canel barium meal contrast examination is shown in Ulcer niche; (4) endoscope's microscopy is as seen to active stage ulcer.
2.2 exclusion standard:
(1) plyability ulcer person; (2) person that has the severe complication, as after piercing operation, massive hemorrhage; (3) observer that affects the treatment with Other diseases; (4) anemia of pregnant woman, maybe can not adhere to therapist; (5) postbulbar duodenal ulcer person.
3, Therapeutic Method
3.1 prescription: Radix Codonopsis 50g, Radix Cudraniae 50g, Radix seu Caulis Kadsurae Heteroclitae 40g, Herba nepenthis 40g, Radix Pedicularis Henryi 30g, Grifola frondosa 30g, Fructus Schisandrae Chinensis 30g, Radix Trichosanthis 20g, Herba menyanthis 20g, Radix Glycyrrhizae 15g.
3.2 method of preparation and use: said medicine technique is routinely made decoction, and 1 dose of every day, every day 2 times, 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Clinical cure: cardinal symptom and minor symptom all disappear, and gastroscopy ulcer disappears fully, local mild hyperaemia, but without obvious edema;
Produce effects: primary symptom all has clear improvement with time disease, and gastroscopy ulcer disappears substantially, still has obvious inflammation;
Effectively: primary symptom all has clear improvement with time disease, and the gastroscopy ulcer surface dwindles more than 50%;
Invalid: primary symptom is with time disease all without improving, and the gastroscopy ulcer surface dwindles not as good as 50%.
4.2 result: in 55 routine patients, recovery from illness 38 examples (69.1%), 14 examples (25.4%) that take a turn for the better, invalid 3 examples (5.5%), total effective rate is 94.5%.
Model case
1, remaining certain, female, 35 years old.Over 3 years, gastric abscess shows effect repeatedly, scorching hot pain, and acid regurgitation, increase the weight of when hungry, must eat alleviation, and scorching being difficult to resolve of defecating, though remission after western medicine repeatly, recurrence again soon.Increased the weight of red tongue, white and thin fur, stringy and rolling pulse, electronic gastroscopy result: duodenal ulcer (active stage) in nearly 2 days.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and conscious gastral cavilty is comfortable, and appetite takes a turn for the better, and continues to take 2 courses for the treatment of, and gastroscopy ulcer disappears fully, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
2, Zhang, man, 45 years old.Gastralgia more than 2 years, increased the weight of to accompany melena 3 days.Patient's gastralgia of repeatedly showing effect over 2 years, when hungry and hypnalgia very, over nearly 3 days, pain increases the weight of, and occurs that stool is shiny black, fatigue and weakness, receive food still can, urine is normal, light red tongue is white, white and thin fur, thready and hesitant pulse.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and gastroscopy ulcer disappears fully, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
3, Wang, man, 53 years old.Vague epigastralgia half a year, previously own the interruption purchased the stomachache medicine and takes, the time during pain only, pain is frequent recently, and pain is obvious when hunger, can alleviate after dining, companion's acid regurgitation, belch, Abdeminal pain sense, the time have nauseating, vomit.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and gastralgia, acid regurgitation alleviate, and Abdeminal pain, nauseating, vomiting disappearance, continue to take 3 courses for the treatment of, and symptom and sign disappears, and gastroscopy ulcer disappears fully, after 1 year, follows up a case by regular visits to without recurring.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment does not only limit the present invention be used to the present invention is described.
Embodiment 1, and a kind of Chinese medicine for the treatment of duodenal ulcer is to be made by Radix Codonopsis 40g, Radix Cudraniae 40g, Radix seu Caulis Kadsurae Heteroclitae 30g, Herba nepenthis 30g, Radix Pedicularis Henryi 20g, Grifola frondosa 20g, Fructus Schisandrae Chinensis 20g, Radix Trichosanthis 10g, Herba menyanthis 10g, Radix Glycyrrhizae 10g.
Embodiment 2, and a kind of Chinese medicine for the treatment of duodenal ulcer is to be made by Radix Codonopsis 50g, Radix Cudraniae 50g, Radix seu Caulis Kadsurae Heteroclitae 40g, Herba nepenthis 40g, Radix Pedicularis Henryi 30g, Grifola frondosa 30g, Fructus Schisandrae Chinensis 30g, Radix Trichosanthis 20g, Herba menyanthis 20g, Radix Glycyrrhizae 15g.
Embodiment 3, and a kind of Chinese medicine for the treatment of duodenal ulcer is to be made by Radix Codonopsis 60g, Radix Cudraniae 60g, Radix seu Caulis Kadsurae Heteroclitae 50g, Herba nepenthis 50g, Radix Pedicularis Henryi 40g, Grifola frondosa 40g, Fructus Schisandrae Chinensis 40g, Radix Trichosanthis 30g, Herba menyanthis 30g, Radix Glycyrrhizae 20g.

Claims (1)

1. Chinese medicine for the treatment of duodenal ulcer is characterized in that it is to be made by following raw material medicaments:
50 parts of Radix Codonopsis, 50 parts of Radix Cudraniaes, 40 parts of Radix seu Caulis Kadsurae Heteroclitae, 40 parts of Herba nepenthiss, 30 parts of Radix Pedicularis Henryis, 30 parts of Grifola frondosa, 30 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Trichosanthis, 20 parts of Herba menyanthiss, 15 parts, Radix Glycyrrhizae.
CN2012104397459A 2012-10-26 2012-10-26 Chinese medicine for treating duodenal ulcer Expired - Fee Related CN102895392B (en)

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Publication number Priority date Publication date Assignee Title
CN104606391A (en) * 2015-01-15 2015-05-13 陈吉美 Traditional Chinese medicine composition for treating duodenal ulcers
CN104958670A (en) * 2015-07-16 2015-10-07 张桂玲 Traditional Chinese medicine for treating qi-collapse type duodenal ulcer

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CN1055223C (en) * 1995-11-24 2000-08-09 何亚长 Chinese medicine preparation for treatment of gastric ulcer, duodenal ulcer and gastritis
CN1240651A (en) * 1998-06-29 2000-01-12 深圳市丰和堂实业有限公司 Health-care food for dropping drug and its preparing process
CN1201772C (en) * 2002-07-26 2005-05-18 杨唐玉 Chinese medicine for treating chronic atrophic gastritis
CN100336546C (en) * 2005-08-03 2007-09-12 蔡青 Chinese medicinal preparation for treating gastroenteric disease
KR101805004B1 (en) * 2010-04-06 2017-12-07 (주)아모레퍼시픽 Fermentation method using medicinal leaf and skin external composition containing fermented extract by the method

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