CN100473401C - Chinese medicine preparation for preventing and treating cerebral thrombus and sequel thereof - Google Patents
Chinese medicine preparation for preventing and treating cerebral thrombus and sequel thereof Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine preparation for preventing and treating cerebral thrombus and its sequelae. The Chinese medicine preparation is prepared with 14 kinds of Chinese medicinal materials, including astragalus root, pseudostellaria root, oyster, polygala root, turtle shell, etc. It is used in preventing and treating cerebral thrombus and its sequelae mainly, and has the advantages of fast acting, high curative effect and no toxic side effect.
Description
Technical field
The present invention relates to the Chinese medicine preparation of a kind of prevention and treatment cerebral thrombosis and sequela, is that a kind of prevention and treatment cerebral thrombosis and sequela are the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Acute cerebrovascular disease is a kind of non-traumatic cerebral local blood circulation obstacle that causes owing to various vascular reasons, one group of disease of focal nervous lesion occurs.Claim apoplexy, apoplexy again.Acute cerebrovascular disease is divided into hemorrhagic and ischemic two big classes according to the etiology and pathology difference clinically.Its sickness rate, disability rate, mortality rate, relapse rate are all very high, and existing data points out that apoplexy is first killer in various countries' cause of death first six digits major disease.1986～nineteen ninety of China is to ten thousand population cerebrovascular morbidity surveys surplus national seven big cities 600, average 215.8/10 ten thousand populations of sickness rate, apoplexy relapse rate 26%.Age and morbidity, being proportionate property of death, the death from cerebral hemorrhage rate is far above cerebral infarction.
Acute cerebrovascular disease belongs to disease categories such as Chinese medicine " apoplexy ", " sudden syncope ", " emotional syncope ", " hemiplegia ", " apoplexy ", " hemiplegia ".Nowadays alleged apoplexy is defined as: " apoplexy is on the basis of QI and blood interior-deficiency; meet the overstrain internal injury, be worried angry, have a liking for inducements such as food savoury, tobacco and wine; and then cause the internal organs imbalance of YIN and YANG; QI and blood is disorderly contrary, and the criminal's of flinging brain forms outside resistance of brain BI-syndrome involved the blood vessels or the blood oozing from the body openings or subcuta neous tissue brain feeling pulse; be primary symptom with the stuttering puckery or aphasia of unexpected confused servant, hemiplegia, facial hemiparalysis, speech, hemianesthesia clinically; and have onset anxious, change fast, as the characteristics that ailment said due to cold or exposure benefaction number becomes, good sending out in a kind of commonly encountered diseases of person in middle and old age.Be divided into hemorrhage apoplexy and ischemia apoplexy by characteristic of disease.”
Western medicine thinks that the factor of acute cerebrovascular disease is varied, and factor that blood vessel wall pathological changes factor, hemodynamics factor, blood constituent change, hemorheological factors etc. are arranged.Though the hypertension modal reason that is cerebral hemorrhage, its pathogenesis still has arguement so far, and simple hypertension is unlikely to cause angiorrhexis, but on the basis of vascular lesion due to the hypertension.The modal cause of disease of cerebral thrombosis is an atherosclerosis, and often with hypertension, rare reason has the inflammation of arterial wall, as tuberculosis, syphilis, suppurative, leptospiral infection, connective tissue disease, allergy arteritis etc., be also shown in congenital vascular malformation, polycythemia vera, blood hypercoagulability etc.
Cerebral hemorrhage, this class acute cerebrovascular disease of cerebral infarction, its sickness rate, case fatality rate, disability rate, relapse rate are still high, this means that Chinese and western medicine lacks effective measures to the treatment of acute cerebrovascular disease.Key is an active prevention, early discovery, early treatment.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The Chinese medicine preparation that the purpose of this invention is to provide a kind of prevention and treatment cerebral thrombosis and sequela.Have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
1～5 part of 1～10 portion of Concha Ostreae of 1～10 part of Radix Pseudostellariae of the Radix Astragali
0.5～3 part in 0.5～3 part of Semen Persicae of 1～5 part of Carapax Trionycis of Radix Polygalae
0.1～2 part of 0.5～3 part of Scolopendra of 0.5～3 portion of Radix Cyathulae of Radix Angelicae Sinensis
0.1～2 part of 0.5～3 portion of Scorpio of 0.5～3 part of Rhizoma Acori Graminei of Flos Carthami
0.5～3 part of 0.5～3 portion of Bombyx Batryticatus of Pheretima.
The weight proportion of each raw material of optimization formula of the present invention is:
2～3 parts of 3～7 portions of Concha Ostreaes of 3～7 parts of Radix Pseudostellariaes of the Radix Astragali
1～2 part in 1～2 part of Semen Persicae of 2～3 parts of Carapax Trionycis of Radix Polygalae
0.5～1.5 part of 1～2 part of Scolopendra of 1～2 portion of Radix Cyathulae of Radix Angelicae Sinensis
0.5～1.5 part of 1～2 portion of Scorpio of 1～2 part of Rhizoma Acori Graminei of Flos Carthami
1～2 part of 1～2 portion of Bombyx Batryticatus of Pheretima.
The weight proportion of each raw material of optimum formula of the present invention is:
2.5 parts of 5 portions of Concha Ostreaes of 5 parts of Radix Pseudostellariaes of the Radix Astragali
1.5 parts in 1.5 parts of Semen Persicaes of 2.5 parts of Carapax Trionycis of Radix Polygalae
1 part of 1.5 parts of Scolopendra of 1.5 portions of Radix Cyathulaes of Radix Angelicae Sinensis
1 part of 1.5 portions of Scorpio of 1.5 parts of Rhizoma Acori Graminei of Flos Carthami
1.5 parts of 1.5 portions of Bombyx Batryticatus of Pheretima.
Drug action mechanism among the present invention is as follows:
Radix Astragali nature and flavor are sweet, warm.Return lung, spleen channel.Have benefit and defend consolidating superficial resistance, inducing diuresis to remove edema, poison holding, the effect of granulation promoting.What be used for that internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle do not burst or burst does not hold back and the disease of all weakness of QI blood deficiency." Chinese medicine medicine for preventing pharmacology and application " the 1074th page.
Sweet, the little hardship of Radix Pseudostellariae nature and flavor, flat.GUIXIN, spleen, lung three warps.Effect with replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.It is tired etc. to treat cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus spontaneous perspiration, deficiency of both vital energy and Yin, spirit." Chinese medicine medicine for preventing pharmacology and application " the 287th page.
The Concha Ostreae nature and flavor are salty, be slightly cold.Return liver, gallbladder, kidney channel.Have tranquillization with heavy prescription, the YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can be used for the palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache pantothenic acid etc." Chinese medicine medicine for preventing pharmacology and application " the 674th page.
Radix Polygalae nature and flavor hardship, suffering, temperature.GUIXIN, kidney, lung meridian.Have the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the repercussive effect.It is swollen etc. to treat phlegm retention, coma, cough, insomnia, palpitation with fear, forgetful, nocturnal emission, carbuncle skin ulcer." Chinese medicine medicine for preventing pharmacology and application " the 620th page.
The Carapax Trionycis nature and flavor are salty, flat.Return the liver,spleen,kidney warp.Have nourishing YIN for suppressing the hyperactive YANG, suppressing the hyperactive liver to relieve the wind syndrome, hard masses softening and resolving, bring down a fever and remove the effect of steaming.Can treat the hot hectic fever due to YIN-deficiency night sweat of consumptive disease, tired, the stirring of wind due to deficiency of YIN of spirit, chronic malaria malaria with splenomegaly, lump in the abdomen addiction piece, hepatosplenomegaly, menoxenia, amenorrhea menometrorrhagia, pediatric epilepsy scared, caries pain etc." Chinese medicine medicine for preventing pharmacology and application " the 1319th page.
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc." Chinese medicine medicine for preventing pharmacology and application " the 553rd page.
Radix Cyathulae property is flat, and sweet and slightly bitter taste is nontoxic.Return liver, kidney channel.Have dispel the wind, dampness removing, the effect of stimulating the menstrual flow, invigorating blood circulation.Can treat rheumatism lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea, lump in the abdomen etc." Chinese medicine voluminous dictionary " the 228th page.
Semen Persicae nature and flavor hardship, sweet, flat.GUIXIN, liver, large intestine channel.Has blood stasis removing and clots absorbing, the effect of loosening bowel to relieve constipation.Can control amenorrhea, dysmenorrhea, WEIJIA, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood etc." Chinese medicine medicine for preventing pharmacology and application " the 986th page.
Flos Carthami nature and flavor suffering, temperature.GUIXIN, Liver Channel.Effect with promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Can treat that amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, traumatic injury etc." Chinese medicine medicine for preventing pharmacology and application " the 604th page.
Rhizoma Acori Graminei nature and flavor suffering, hardship, temperature.GUIXIN, stomach warp.Have removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, tranquillizing and allaying excitement, ward off dirty parasite killing, blood pressure lowering, spasmolytic, anti-inflammation, the effect of detoxifying, regulate the flow of vital energy, invigorating blood circulation.Can treat epilepsy, expectorant febrile convulsion, calentura coma, forgetful, deafness with qi stagnation, ambition unhappiness, anemofrigid-damp arthralgia, stomachache, distension and fullness in the abdomen, enteritis, dysentery, chronic bronchitis, infantile pneumonia, sputum obturation, obnubilation, carbuncle tinea scabies, traumatic injury etc." Chinese medicine medicine for preventing pharmacology and application " the 399th page.
Scolopendra nature and flavor suffering, temperature, poisonous.Return Liver Channel.Effect with endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Can treat that infantile convulsion, tic spasm, middle air port are askew, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom etc." Chinese medicine medicine for preventing pharmacology and application " the 1238th page.
Scorpio nature and flavor suffering, flat, poisonous.Return Liver Channel.Effect with endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Can treat that infantile convulsion, tic spasm, middle air port are askew, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula etc." Chinese medicine medicine for preventing pharmacology and application " the 581st page.
Bombyx Batryticatus nature and flavor suffering is salty, flat.Return liver, lung, stomach warp.Effect with expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Can treat apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis etc." Chinese medicine voluminous dictionary " the 739th page.
The Pheretima nature and flavor are salty, cold.Go into liver, spleen, lung, urinary bladder channel.Have heat clearing away, suppressing the hyperactive liver, Zhichuan, collateral dredging diuretic effect.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pant, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection, hyperpyrexia, bronchial asthma, hypertension, psychosis, ulcer of the lower limb, eczema, erysipelas, burn and scald, fracture etc." Chinese medicine medicine for preventing pharmacology and application " the 522nd page
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch with the Radix Astragali, Radix Pseudostellariae; Concha Ostreae, Carapax Trionycis, Radix Angelicae Sinensis, Radix Cyathulae, Semen Persicae, Flos Carthami, Bombyx Batryticatus and Pheretima are minister; Radix Polygalae, Rhizoma Acori Graminei, Scolopendra and Scorpio make for assistant.All medicines are harmonious, altogether the effect of tool replenishing QI to invigorate the spleen, nourishing YIN for suppressing the hyperactive YANG, the Fructus Alpiniae Oxyphyllae of calming the nerves, promoting blood circulation to remove obstruction in the collateral.Prevention and treatment cerebral thrombosis and sequela determined curative effect, toxic and side effects is little, taking convenience.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.
Preparation of the present invention, peroral dosage form preferably, as: tablet capsule agent, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes comprehensive function prevention and the treatment cerebral thrombosis and the sequela of the Chinese medicine of respectively distinguishing the flavor of, and does not have chemical sweeting agent, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and mice is 35g crude drug/kg to the maximum tolerated dose of medicine of the present invention, is 135 times of clinical people's consumption, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention can treat cerebral thrombosis and sequela effectively, and the prevention of brain thrombosis also has better curative effect, has improved patient's life quality and the time greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to treatment cerebral thrombosis and sequela.The criterion of traditional Chinese medical science sign is as follows: (the 104th page of " new Chinese medicine clinical research guideline " Zheng Xiao cornel chief editor Chinese Medicine science and technology publishing house in May, 2002 front page).
1, clinical recovery tcm clinical practice symptom, sign disappear or basic the disappearance; The sign integration reduces 〉=95%.
2, produce effects tcm clinical practice symptom, sign are obviously improved, and the sign integration reduces 〉=70%.
3, improvement tcm clinical practice symptom, sign all take a favorable turn, and the sign integration reduces 〉=30%.
4, invalid tcm clinical practice symptom, sign do not have obvious improvement, even increase the weight of, the sign integration reduces less than 30%.
For showing medicine of the present invention, as follows through clinical test results to treatment cerebral thrombosis and sequela therapeutic effect; Treatment cerebral thrombosis and sequela patient 60 examples, the age is 40～86 years old, male's 26 examples, women's 34 examples.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.28 examples of fully recovering account for 46.7%, and produce effects 18 examples account for 30%, and effective 10 examples account for 16.7%, and invalid 4 examples account for 6.7%, and total effective rate reaches more than 93%.After three course of therapy, symptoms such as patient's hemiplegia, facial hemiparalysis, slurred speech all have obvious change.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
2.5 parts of 5 portions of Concha Ostreaes of 5 parts of Radix Pseudostellariaes of the Radix Astragali
1.5 parts in 1.5 parts of Semen Persicaes of 2.5 parts of Carapax Trionycis of Radix Polygalae
1 part of 1.5 parts of Scolopendra of 1.5 portions of Radix Cyathulaes of Radix Angelicae Sinensis
1 part of 1.5 portions of Scorpio of 1.5 parts of Rhizoma Acori Graminei of Flos Carthami
1.5 parts of 1.5 portions of Bombyx Batryticatus of Pheretima.
Preparation method is to get Carapax Trionycis earlier, Scolopendra, Scorpio and Bombyx Batryticatus drying and crushing to 120～200 order fine powders, get the Radix Astragali again, Radix Pseudostellariae, Concha Ostreae, Radix Polygalae, Radix Angelicae Sinensis, the Radix Cyathulae Semen Persicae, Flos Carthami, Rhizoma Acori Graminei and Pheretima decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Carapax Trionycis, Scolopendra, Scorpio and Bombyx Batryticatus fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
2.5 parts of 5 portions of Concha Ostreaes of 5 parts of Radix Pseudostellariaes of the Radix Astragali
1.5 parts in 1.5 parts of Semen Persicaes of 2.5 parts of Carapax Trionycis of Radix Polygalae
1 part of 1.5 parts of Scolopendra of 1.5 portions of Radix Cyathulaes of Radix Angelicae Sinensis
1 part of 1.5 portions of Scorpio of 1.5 parts of Rhizoma Acori Graminei of Flos Carthami
1.5 parts of 1.5 portions of Bombyx Batryticatus of Pheretima.
Preparation method is to get Carapax Trionycis earlier, Scolopendra, Scorpio and Bombyx Batryticatus drying and crushing to 120～200 order fine powders, get the Radix Astragali again, Radix Pseudostellariae, Concha Ostreae, Radix Polygalae, Radix Angelicae Sinensis, the Radix Cyathulae Semen Persicae, Flos Carthami, Rhizoma Acori Graminei and Pheretima decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Carapax Trionycis, Scolopendra, Scorpio and Bombyx Batryticatus fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
2.5 parts of 5 portions of Concha Ostreaes of 5 parts of Radix Pseudostellariaes of the Radix Astragali
1.5 parts in 1.5 parts of Semen Persicaes of 2.5 parts of Carapax Trionycis of Radix Polygalae
1 part of 1.5 parts of Scolopendra of 1.5 portions of Radix Cyathulaes of Radix Angelicae Sinensis
1 part of 1.5 portions of Scorpio of 1.5 parts of Rhizoma Acori Graminei of Flos Carthami
1.5 parts of 1.5 portions of Bombyx Batryticatus of Pheretima.
Preparation method is to get Carapax Trionycis earlier, Scolopendra, Scorpio and Bombyx Batryticatus drying and crushing to 120～200 order fine powders, get the Radix Astragali again, Radix Pseudostellariae, Concha Ostreae, Radix Polygalae, Radix Angelicae Sinensis, the Radix Cyathulae Semen Persicae, Flos Carthami, Rhizoma Acori Graminei and Pheretima decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Carapax Trionycis, Scolopendra, Scorpio and Bombyx Batryticatus fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, one month is a course of treatment.
Claims (3)
1, the Chinese medicine preparation of a kind of prevention and treatment cerebral thrombosis and sequela is characterized in that it is made by following raw materials by weight proportions:
1～5 part of 1～10 portion of Concha Ostreae of 1～10 part of Radix Pseudostellariae of the Radix Astragali
0.5～3 part in 0.5～3 part of Semen Persicae of 1～5 part of Carapax Trionycis of Radix Polygalae
0.1～2 part of 0.5～3 part of Scolopendra of 0.5～3 portion of Radix Cyathulae of Radix Angelicae Sinensis
0.1～2 part of 0.5～3 portion of Scorpio of 0.5～3 part of Rhizoma Acori Graminei of Flos Carthami
0.5～3 part of 0.5～3 portion of Bombyx Batryticatus of Pheretima.
2, the Chinese medicine preparation of a kind of prevention according to claim 1 and treatment cerebral thrombosis and sequela, wherein the weight proportion of each crude drug is:
2～3 parts of 3～7 portions of Concha Ostreaes of 3～7 parts of Radix Pseudostellariaes of the Radix Astragali
1～2 part in 1～2 part of Semen Persicae of 2～3 parts of Carapax Trionycis of Radix Polygalae
0.5～1.5 part of 1～2 part of Scolopendra of 1～2 portion of Radix Cyathulae of Radix Angelicae Sinensis
0.5～1.5 part of 1～2 portion of Scorpio of 1～2 part of Rhizoma Acori Graminei of Flos Carthami
1～2 part of 1～2 portion of Bombyx Batryticatus of Pheretima.
3, the Chinese medicine preparation of a kind of prevention according to claim 1 and treatment cerebral thrombosis and sequela, wherein the weight proportion of each crude drug is:
2.5 parts of 5 portions of Concha Ostreaes of 5 parts of Radix Pseudostellariaes of the Radix Astragali
1.5 parts in 1.5 parts of Semen Persicaes of 2.5 parts of Carapax Trionycis of Radix Polygalae
1 part of 1.5 parts of Scolopendra of 1.5 portions of Radix Cyathulaes of Radix Angelicae Sinensis
1 part of 1.5 portions of Scorpio of 1.5 parts of Rhizoma Acori Graminei of Flos Carthami
1.5 parts of 1.5 portions of Bombyx Batryticatus of Pheretima.
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| CN112870266A (en) * | 2021-03-26 | 2021-06-01 | 赵凤臣 | Traditional Chinese medicine formula for treating cerebral thrombosis |
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| Title |
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| 中药治疗29例脑血栓形成临床小结. 巫少青.江西中医药，第28卷第5期. 1997 |
| 中药治疗29例脑血栓形成临床小结. 巫少青.江西中医药，第28卷第5期. 1997 * |
| 利用《内经》理论治疗脑血栓形成48例体会. 王丹虹.实用乡村医生杂志，第1期. 1996 |
| 利用《内经》理论治疗脑血栓形成48例体会. 王丹虹.实用乡村医生杂志，第1期. 1996 * |
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