CN101028490A - Chinese medicine for treating acne - Google Patents
Chinese medicine for treating acne Download PDFInfo
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- CN101028490A CN101028490A CN 200710065473 CN200710065473A CN101028490A CN 101028490 A CN101028490 A CN 101028490A CN 200710065473 CN200710065473 CN 200710065473 CN 200710065473 A CN200710065473 A CN 200710065473A CN 101028490 A CN101028490 A CN 101028490A
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Abstract
A Chinese medicine for treating acne is prepared from more than 10 Chinese-medicinal materials including mulberry bark, loquat leaf, honeysuckle flower, motherwort, etc.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of acne, is that a kind of acne for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Acne is commonly called as " acne ", " comedo ", be a kind of teen-age chronic skin inflammation that is mainly in, along with the raising day by day of living standard, the sickness rate of acne is more and more higher, and it is not to be regardless of region, age and sex, the trend that sickness rate all is significantly improved.The whole world has several hundred million ten thousand patient earnestly being tormented by irritating acne, the popularity of acne investigation is in recent years found, the teenager sickness rate in 11-25 year reaches more than 80%, adolescence's sickness rate of 25-35 reaches more than 15%, as untimely treatment or prevent and treat improper, can leave over the cicatrix that lifelong difficulty heals, and influence appearance, make numerous young patients very worried.
But the research of this disease and treatment do not obtain the extensive attention of world medical circle.Though caused the concern on beauty treatment circle, all there is every day new product to occur, not only do not have this disease of systematized healing, be that patient's sickness rate is more and more higher on the contrary.How does acne take place on earth so? how grown acne should treat, and has become the topic that people extremely pay close attention to.
The occurrence cause of acne is complicated, and is relevant with multiple factor, unreasonable as dietary structure, psychentonia, and the viscera function disorder, life or working environment are not good, some trace element deficiency, inherited genetic factors, constipation etc.But main inducing is an adolescence reaches maturity, and the androgen level raises in the body, and the epithelial cell that stimulates sebum and hair follicle to come off, be gathered into yellow-white material thromboembolism in hair in, promptly form the current acne of powder.Be difficult to discharge and the little pimple of canescence that forms as the little sebum of follicular orifice, be hoary hair's acne.The acne that are exposed to the follicular orifice outside are become black by pollutions such as air, dusts, are blackhead.The follicular canal intracavity also exists a large amount of propionibacterium acness in addition.Sebum is resolved into unsaturated fatty acid, cause hair follicle and the not inflammation of equal extent takes place on every side, and appearanceization is dense, tuberosity, cyst or sebaceous cyst etc., prolonged and repeated inflammation can stay the cicatrix that difficulty heals on the face, make the skin injustice, coarse ugly, and sebaceous secretion is not smooth, inflammation increases the weight of to stimulate sebaceous secretion to form vicious cycle again repeatedly.
The method of western medical treatment primary disease is a lot, but great majority can only reach recent clinical effectiveness, and can not prevent recurrence, and has toxic and side effects in various degree.The differential diagnosis in tcm treatment obtains effect preferably, and does not recur.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of acne, and have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.5～6 parts of Fructus Forsythiaes of 1.5～6 parts of Folium Eriobotryaes of Cortex Mori
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 0.1～2 part of Flos Chrysanthemi Indici of Radix Gentianae
1.0～4 parts in 1.0～4 parts of Semen Persicaes of 1.5～6 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
0.1～2 part of 0.1～2 part of Radix Bupleuri of 1.0～4 portions of Semen Plantaginiss of Flos Lonicerae
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of Fructus Forsythiaes of 2.5～3.5 parts of Folium Eriobotryaes of Cortex Mori
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 0.5～1.5 part of Flos Chrysanthemi Indici of Radix Gentianae
1.5～2.5 parts in 1.5～2.5 parts of Semen Persicaes of 2.5～3.5 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
0.5～1.5 part of 0.5～1.5 part of Radix Bupleuri of 1.5～2.5 portions of Semen Plantaginiss of Flos Lonicerae
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of Fructus Forsythiaes of 3 parts of Folium Eriobotryaes of Cortex Mori
2 parts of 2 portions of Rhizoma Alismatis of 1 part of Flos Chrysanthemi Indici of Radix Gentianae
2 parts in 2 parts of Semen Persicaes of 3 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
1 part of 1 part of Radix Bupleuri of 2 portions of Semen Plantaginiss of Flos Lonicerae
Drug action mechanism among the present invention is as follows:
The Cortex Mori nature and flavor are sweet, hot, and are cold.Return lung, spleen channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Cure mainly the fullness in the chest that lung-heat or diseases caused by retention of fluid stop lung and breath with cough hemoptysis, edema, beriberi, dysuria etc.(the 2787th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Folium Eriobotryae nature and flavor hardship, cold.Attach to the lung and stomach meridians.Have lung heat clearing, stomach function regulating, sending down the abnormal ascending QI quenches the thirst etc.Cure mainly the cough due to lung-heat, deficiency of YIN chronic cough, the gastric heat sound of vomiting of vomitting, pregnancy reactions is quenched one's thirst, and lung-wind syndrome acne vulgaris ， acne rosacea is red etc.(the 1802nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension dizziness tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 413rd page).
Flos Chrysanthemi Indici nature and flavor hardship, suffering, cold.Return lung, Liver Channel.Has heat-clearing and toxic substances removing, the effect of dispelling wind suppressing the hyperactive liver.Cure mainly furuncle, carbuncle, erysipelas, eczema, dermatitis, anemopyretic cold, laryngopharynx swelling and pain, headache, dizzy etc.(the 2968th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Flos Lonicerae nature and flavor are sweet, cold.Return lung, the heart, stomach warp.Has heat-clearing and toxic substances removing, the effect of wind-heat dissipating.Can treat the carbuncle furuncle, scrofula anal fistula, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 830th page).
Fructus Forsythiae nature and flavor hardship, be slightly cold.Return lung, the heart, small intestine meridian.Have heat-clearing and toxic substances removing, the knot that disappears looses swollen, and the diuretic effect clears away heart-fire.Can treat carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, hyperpyrexia excessive thirst, coma send out speckle, pyretic stranguria urine retention etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 669th page).
Herba Leonuri nature and flavor hardship, suffering, be slightly cold.Return liver, pericardium channel.Effect with regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis, inducing diuresis to remove edema.Can treat menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, have blood in stool, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1050th page).
The Rhizoma Alismatis nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Has diuresis, the effect of clearing away damp-heat.Can treat dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia etc.(the 184th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Stir-baked RHIIZOMA CURCUMAE with vinegar nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Semen Persicae (parched) property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Have reconciling superficies and interior, soothing the liver, the effect of yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
The Semen Plantaginis nature and flavor are sweet, be slightly cold.Return liver, kidney, lung, small intestinal, urinary bladder channel.Has clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, the effect of removing heat from the lung and dissipating phlegm.Can treat the cough due to lung-heat, urinary system infection, calculus, gastritis, dysuria, enteritis, bacillary dysentery, acute icterohepatitisshock, bronchitis, acute eye conjunctivitis, stranguria with turbid discharge, leukorrhagia, hematuria, edema, hematodiarrhoea is had loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat tonsillitis, cough, skin ulcer etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 291st page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cortex Mori, Folium Eriobotryae, Radix Gentianae and Flos Chrysanthemi Indici, is ministerial drug with Flos Lonicerae, Fructus Forsythiae, Herba Leonuri, Rhizoma Alismatis, stir-baked RHIIZOMA CURCUMAE with vinegar and Semen Persicae, is adjuvant with Radix Bupleuri and Semen Plantaginis.All medicine phases and common tool heat-clearing and toxic substances removing, the effect of blood stasis-eliminating and stagnation-dissipating, the treatment acne has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese patent medicine of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese patent medicine of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, preferred Chinese patent medicine is a peroral dosage form, as: tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese patent medicine is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment acne of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat acne, and the prevention of acne is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify medicine of the present invention to treatment remedy of acne effect below by the clinical practice example
As follows through clinical test results; Treatment patients with acne 28 examples.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 15 examples and account for 53.6%, 11 examples that take a turn for the better account for 39.3%, and more 2 examples do not account for 7.1%, and total effective rate reaches 92.9%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
2 parts of 3 parts of Fructus Forsythiaes of 3 parts of Folium Eriobotryaes of Cortex Mori
2 parts of 2 portions of Rhizoma Alismatis of 1 part of Flos Chrysanthemi Indici of Radix Gentianae
2 parts in 2 parts of Semen Persicaes of 3 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
1 part of 1 part of Radix Bupleuri of 2 portions of Semen Plantaginiss of Flos Lonicerae
Preparation method is to get above-mentioned raw materials to clean, and roguing decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
2 parts of 3 parts of Fructus Forsythiaes of 3 parts of Folium Eriobotryaes of Cortex Mori
2 parts of 2 portions of Rhizoma Alismatis of 1 part of Flos Chrysanthemi Indici of Radix Gentianae
2 parts in 2 parts of Semen Persicaes of 3 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
1 part of 1 part of Radix Bupleuri of 2 portions of Semen Plantaginiss of Flos Lonicerae
Preparation method is to get above-mentioned raw materials to clean, and roguing decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, be concentrated into the clear paste of relative density 1.30～1.32 when 50 degree～55 are spent, drying is ground into fine powder, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
2 parts of 3 parts of Fructus Forsythiaes of 3 parts of Folium Eriobotryaes of Cortex Mori
2 parts of 2 portions of Rhizoma Alismatis of 1 part of Flos Chrysanthemi Indici of Radix Gentianae
2 parts in 2 parts of Semen Persicaes of 3 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
1 part of 1 part of Radix Bupleuri of 2 portions of Semen Plantaginiss of Flos Lonicerae
Preparation method is to get above-mentioned raw materials to clean, roguing, decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, and the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, one month is a course of treatment.
Claims (6)
1, a kind of Chinese patent medicine for the treatment of acne is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.5～6 parts of Fructus Forsythiaes of 1.5～6 parts of Folium Eriobotryaes of Cortex Mori
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 0.1～2 part of Flos Chrysanthemi Indici of Radix Gentianae
1.0～4 parts in 1.0～4 parts of Semen Persicaes of 1.5～6 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
0.1～2 part of 0.1～2 part of Radix Bupleuri of 1.0～4 portions of Semen Plantaginiss of Flos Lonicerae.
2, a kind of Chinese patent medicine for the treatment of acne according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 2.5～3.5 parts of Fructus Forsythiaes of 2.5～3.5 parts of Folium Eriobotryaes of Cortex Mori
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 0.5～1.5 part of Flos Chrysanthemi Indici of Radix Gentianae
1.5～2.5 parts in 1.5～2.5 parts of Semen Persicaes of 2.5～3.5 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
0.5～1.5 part of 0.5～1.5 part of Radix Bupleuri of 1.5～2.5 portions of Semen Plantaginiss of Flos Lonicerae.
3, a kind of Chinese patent medicine for the treatment of acne according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 3 parts of Fructus Forsythiaes of 3 parts of Folium Eriobotryaes of Cortex Mori
2 parts of 2 portions of Rhizoma Alismatis of 1 part of Flos Chrysanthemi Indici of Radix Gentianae
2 parts in 2 parts of Semen Persicaes of 3 parts of stir-baked RHIIZOMA CURCUMAE with vinegar of Herba Leonuri
1 part of 1 part of Radix Bupleuri of 2 portions of Semen Plantaginiss of Flos Lonicerae.
4, the Chinese patent medicine of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese patent medicine of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese patent medicine of claim 4 is capsule, tablet, granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710065473 CN101028490A (en) | 2007-04-16 | 2007-04-16 | Chinese medicine for treating acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710065473 CN101028490A (en) | 2007-04-16 | 2007-04-16 | Chinese medicine for treating acne |
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| Publication Number | Publication Date |
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| CN101028490A true CN101028490A (en) | 2007-09-05 |
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| CN 200710065473 Pending CN101028490A (en) | 2007-04-16 | 2007-04-16 | Chinese medicine for treating acne |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101716263B (en) * | 2009-12-21 | 2013-05-29 | 罗蔚 | Traditional Chinese medicine external use preparation for acne treatment |
| CN103638335A (en) * | 2013-12-21 | 2014-03-19 | 滨州医学院附属医院 | Traditional Chinese medicine for treating refractory acne and preparation method thereof |
| CN106306231A (en) * | 2015-10-19 | 2017-01-11 | 宁夏清华园知识产权研究与开发有限公司 | Chinese herbal medicine tea having effects of removing acne and beautifying skin |
| CN107715076A (en) * | 2017-12-04 | 2018-02-23 | 张致恒 | A kind of Chinese medicine preparation for treating hemorrhoid and preparation method thereof |
-
2007
- 2007-04-16 CN CN 200710065473 patent/CN101028490A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101716263B (en) * | 2009-12-21 | 2013-05-29 | 罗蔚 | Traditional Chinese medicine external use preparation for acne treatment |
| CN103638335A (en) * | 2013-12-21 | 2014-03-19 | 滨州医学院附属医院 | Traditional Chinese medicine for treating refractory acne and preparation method thereof |
| CN106306231A (en) * | 2015-10-19 | 2017-01-11 | 宁夏清华园知识产权研究与开发有限公司 | Chinese herbal medicine tea having effects of removing acne and beautifying skin |
| CN107715076A (en) * | 2017-12-04 | 2018-02-23 | 张致恒 | A kind of Chinese medicine preparation for treating hemorrhoid and preparation method thereof |
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Open date: 20070905 |