CN1943699A - A Chinese traditional medicinal preparation for treatment of eczema - Google Patents

A Chinese traditional medicinal preparation for treatment of eczema Download PDF

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CN1943699A
CN1943699A CN 200610113951 CN200610113951A CN1943699A CN 1943699 A CN1943699 A CN 1943699A CN 200610113951 CN200610113951 CN 200610113951 CN 200610113951 A CN200610113951 A CN 200610113951A CN 1943699 A CN1943699 A CN 1943699A
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eczema
fructus
chinese medicine
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CN100415265C (en
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王信锁
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Abstract

This invention relates to a Chinese traditional medicinal preparation for treatment of eczema. It takes gentian root, fried astragalus root, densegruit pittany bark,astragalus root,motherword herb, oriental waterplantain rhizome, salted Chinese corktree bark, kuhseng, cicada slough,glabrous greenbrier rhizome,fructus forsythiae, giant knotweed rhizome, sevenlobed yam rhizome, virgate wormwood herb and fresh licorice root as raw material and prepared.This preparation has the effects of Clearing heat and Benefiting damp, purping fire and relieving annoyance, dispelling wind and arresting itching. It has sure curative effect in treating and protecting eczema but without tonxin and side effects. It is easy to take and the cost is low.

Description

A kind of Chinese medicine preparation for the treatment of eczema
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of eczema, is that a kind of eczema for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Eczema is a kind of modal anaphylaxis, inflammatory skin disease, and skin lesion often is a pleomorphism, acute pruritus, and outbreak easily is the chronic feature that turns to repeatedly.Can be divided into acute, subacute and chronic three phases by its outbreak stage clinically.According to main skin lesion form difference, eczema erythematosum, papular eczema, chickenpox eczema, abscess eczema, erosive eczema, incrustation property eczema, eczemasquamosum etc. are then arranged, according to the difference of happening part, eczema capitis, facial eczema, ear eczema, eczema of nipple, omphalos eczema, clitoris eczema, anal eczema, hand eczema etc. are arranged then.
The traditional Chinese medical science is referred to as acute eczema, misfortune skin ulcer, eczema of ear, eczema of scrotum, atopic eczema etc., and the person that is called the eczema is also arranged.Put down in writing as " Yizong Jinjian surgery heart method ": " this card is nascent as scabies, when pruritus does not have, spreads incessantly, grabs Tianjin yellow fluid, and contamination in flakes." and for example " General Treatise on the Cause and Symptoms of Diseases " misfortune skin ulcer wait record: " skin ulcer person, by skin natural fibre line of meat void, the gas of rheumatism, the folding vim and vigour, the poly-institute of knot gives birth to ... pass relatively, as newborn Fructus Evodiae, sufferings are grabbed and are scratched into skin ulcer, and yellow juice goes out, contaminate and grow, jackknifing, the time play when being recovered.”
Chinese medicine thinks that eczema is not anti-because of natural disposition, and rheumatic fever visitor forms in skin; Or because of dysfunction of the spleen in transportation or nutrient QI and blood being insufficient, damp and hot staying, so that blood-deficiency and wind-dry are due to the damp and hot pent-up of wind-dryness, the failure of skin and muscle to be nourished.The many duties of eczema acute attack in the heart, subacute, chronic phase how duties in spleen, liver.Doctor trained in Western medicine thinks that the pathogenic factor of eczema is very complicated, and the interaction of internal factor and extrinsic factor is arranged, and often is many-sided.Extrinsic factor such as living environment, weather conditions etc. all can influence the generation of eczema.Spirit such as internal factor such as chronic digestive system disease, gastrointestinal function obstacle, psychentonia, insomnia, overwork, emotion changes changes, and infection focus, dysbolism and endocrine function imbalance etc. all can produce or add the state of an illness of celsus' papules.
The traditional Chinese medical science to Coryza Treated by Syndrome Differentiation acute, subacute eczema often be divided into wind heat accumulate skin, rheumatism accumulate skin, damp-heat gluing each other thermogravimetric in wet, damp-heat gluing each other damp and hotly lay equal stress on, the damp-heat gluing each other weight in wet base is violated on heat, the wet resistance of stagnation of liver-QI, spleen-dampness and stomach-heat fumigation etc., and the disease type is treated.The Coryza Treated by Syndrome Differentiation of chronic eczema often is divided into the disease type such as insufficiency of the spleenly wetly accumulates, the wet stasis of blood is tied mutually, insufficiency of the spleen blood is dry, deficiency of YIN folder is wet, deficiency of YIN blood is dry, QI and blood is retarded by silt, wind contains that blood is dry, the hepatic and renal YIN deficiency, spleen sun are not transported in the humidity hysteresis Jiao and treat.Because doctor trained in Western medicine is unclear to the etiology and pathology of primary disease, so in treatment, lack etiological treatment measure and active drug, and bias toward anti symptom treatment, as avoid local excitation, use antihistaminic, topical application corticosteroid hormone class medicine is coated with outward, but these treatment weak curative effects, and cure or the back relapse rate height that takes a turn for the better, side effect is still arranged as prolonged application.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of eczema.Have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
0.1~2 part of 1~4 portion of Rhizoma Alismatis of 0.1~2 part of Fructus Gardeniae (parched) of Radix Gentianae
1~4 part of 1~4 part of Radix Sophorae Flavescentis of 0.1~2 part of Cortex Dictamni of the Fructus Kochiae
1~4 part of 1.5~6 parts of Fructus Forsythiae of 0.1~2 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
0.1~2 part of 0.1~1 part of Rhizoma Polygoni Cuspidati of 1.5~6 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1~4 part of 0.1~2 portion of Herba Artemisiae Scopariae of 0.1~2 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
The weight proportion of each raw material of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 portions of Rhizoma Alismatis of 0.5~1.5 part of Fructus Gardeniae (parched) of Radix Gentianae
1.5~2.5 parts of 1.5~2.5 parts of Radix Sophorae Flavescentiss of 0.5~1.5 part of Cortex Dictamni of the Fructus Kochiae
1.5~2.5 parts of 2.5~3.5 parts of Fructus Forsythiaes of 0.5~1.5 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
0.5~1.5 part of 0.3~0.7 part of Rhizoma Polygoni Cuspidati of 2.5~3.5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5~2.5 parts of 0.5~1.5 portion of Herba Artemisiae Scopariaes of 0.5~1.5 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 portions of Rhizoma Alismatis of 1 part of Fructus Gardeniae (parched) of Radix Gentianae
2 parts of 2 parts of Radix Sophorae Flavescentiss of 1 part of Cortex Dictamni of the Fructus Kochiae
2 parts of 3 parts of Fructus Forsythiaes of 1 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
1 part of 0.5 part of Rhizoma Polygoni Cuspidati of 3 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
2 parts of 1 portion of Herba Artemisiae Scopariaes of 1 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
Drug action mechanism among the present invention is as follows:
Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension dizziness tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 413rd page).
Fructus Gardeniae (parched) nature and flavor hardship, cold.GUIXIN, lung, tri-jiao channel.Effect with pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, cool thermal detoxification.Can treat that calentura restlessness of asrhenia type and insomnia, calentura are vexed, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tell nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles, external treatment bruise pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 865th page).
Cortex Dictamni nature and flavor hardship, cold.Return spleen, stomach, urinary bladder channel.Has heat clearing and damp drying, the antidotal effect of dispeling the wind.Can treat damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine etc.(the 83rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Fructus Kochiae nature and flavor suffering, hardship, cold.Return kidney, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of dispelling wind for relieving itching.Can treat difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus etc.(the 93rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Herba Leonuri nature and flavor hardship, suffering, be slightly cold.Return liver, pericardium channel.Effect with regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis, inducing diuresis to remove edema.Can treat menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, have blood in stool, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1050th page).
The Rhizoma Alismatis nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Have diuretic, eliminating dampness by diuresis, the effect that expels the heat-evil can be treated dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria etc.(" Chinese medicine voluminous dictionary " the 1461st page).
Stir-baked CORTEX PHELLODENDRI with salt solution nature and flavor hardship, cold.Return kidney, urinary bladder channel.Have heat clearing and damp drying, pathogenic fire purging removes steams, and the effect of skin ulcer is treated in detoxifcation.Can treat damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Can treat hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency etc.(the 251st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Sophorae Flavescentis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Has heat clearing and damp drying, parasite killing, diuretic effect.Can treat hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis etc.(the 161st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Periostracum Cicadae nature and flavor are sweet, salty, cold.Return lung, Liver Channel.Has diffusing wind heat extraction, sore-throat relieving, rash, nebula removing, the effect of spasmolytic.Can treat anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1254th page).
The Rhizoma Smilacis Glabrae nature and flavor are sweet, light, flat.Return liver, stomach warp.Has heat-clearing and toxic substances removing, wind-damp dispelling, bone and muscle strengthening, sharp joint, anticancer effect.Can treat damp and hot sore, eczema, rheumatic ostalgia, limbs contracture, Fructus Myricae rubrae malignant boil, urinary system infection, syphilis, stranguria with turbid discharge, stranguria leucorrhea, dyspepsia, diarrhoea, beriberi, furuncle, carbuncle, scrofula etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 87th page).
Fructus Forsythiae nature and flavor hardship, be slightly cold.Return lung, the heart, small intestine meridian.Have heat-clearing and toxic substances removing, the knot that disappears looses swollen, and the diuretic effect clears away heart-fire.Can treat carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, hyperpyrexia excessive thirst, coma send out speckle, pyretic stranguria urine retention etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 669th page).
The Rhizoma Polygoni Cuspidati mildly bitter flavor is slightly cold.Return liver, gallbladder, lung meridian.Has expelling wind and removing dampness, dissipating blood stasis analgesic therapy, the effect of relieving cough and resolving phlegm.Can treat arthralgia, jaundice due to damp-heat, amenorrhea , mass in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm etc.(the 168th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Dioscorea septemloba Thunb.  nature and flavor hardship, flat.Return kidney, stomach warp.Have dampness removing go turbid, the effect of the blood stasis dispelling that dispels the wind.Can treat the gonorrhea nebulousurine, leukorrhagia, damp and hot sore, waist knee joint arthralgia pain etc.(the 271st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Herba Artemisiae Scopariae nature and flavor hardship, suffering are slightly cold.Return spleen, stomach, liver, gallbladder meridian.Has clearing away damp-heat, the effect of jaundice eliminating subcutaneous ulcer.Can treat the jaundice oliguria, the eczema pruritus; Infectious jaundice type hepatitis etc.(the 192nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Glycyrrhizae nature and flavor are sweet, and are flat.GUIXIN, lung, spleen, stomach warp.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong etc.(the 66th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Gentianae, Rhizoma Smilacis Glabrae, Dioscorea septemloba Thunb.  and Herba Artemisiae Scopariae; With Fructus Gardeniae (parched), Cortex Dictamni, the Fructus Kochiae, Herba Leonuri, stir-baked CORTEX PHELLODENDRI with salt solution, Radix Sophorae Flavescentis, Periostracum Cicadae, Fructus Forsythiae and Rhizoma Polygoni Cuspidati is ministerial drug; With Rhizoma Alismatis and Radix Glycyrrhizae is adjuvant.All medicines are harmonious, altogether the effect of tool clearing away heat-damp and promoting diuresis, pathogenic fire purging relieving restlessness, dispelling wind for relieving itching.Treatment eczema determined curative effect, toxic and side effects is little, taking convenience.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.
Preparation of the present invention, peroral dosage form preferably, as: tablet capsule agent, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment eczema of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat eczema, and the prevention of eczema is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to treatment eczema.The criterion of traditional Chinese medical science sign is as follows: (the 298th page of " new Chinese medicine clinical research guideline " Zheng Xiao cornel chief editor Chinese Medicine science and technology publishing house in May, 2002 front page).
1, clinical recovery tcm clinical practice symptom, sign disappear or basic the disappearance; The sign integration reduces 〉=95%.
2, produce effects tcm clinical practice symptom, sign are obviously improved, and 95%>sign integration reduces 〉=70%.
3, effectively tcm clinical practice symptom, sign all take a favorable turn, and 70%>sign integration reduces 〉=50%.
4, invalid tcm clinical practice symptom, sign do not have obvious improvement, even increase the weight of, the sign integration reduces less than 50%.
For showing medicine of the present invention, as follows through clinical test results to treatment eczema treatment effect; Treatment eczema patients 32 examples, the age is 18~72 years old, male's 20 examples, women's 12 examples.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.22 examples of fully recovering account for 68.75%, and produce effects 5 examples account for 15.6%, and effective 3 examples account for 9.37%, and invalid 2 examples account for 6.25%, and total effective rate reaches more than 93%.After three course of therapy, symptoms such as patient's erythema, pimple, vesicle, pruritus all have clear improvement.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
1 part of 2 portions of Rhizoma Alismatis of 1 part of Fructus Gardeniae (parched) of Radix Gentianae
2 parts of 2 parts of Radix Sophorae Flavescentiss of 1 part of Cortex Dictamni of the Fructus Kochiae
2 parts of 3 parts of Fructus Forsythiaes of 1 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
1 part of 0.5 part of Rhizoma Polygoni Cuspidati of 3 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
2 parts of 1 portion of Herba Artemisiae Scopariaes of 1 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
Preparation method is to get Periostracum Cicadae drying and crushing to 120~200 order fine powders earlier, get Radix Gentianae again, Fructus Gardeniae (parched), Cortex Dictamni, the Fructus Kochiae, Herba Leonuri, Rhizoma Alismatis, stir-baked CORTEX PHELLODENDRI with salt solution, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Dioscorea septemloba Thunb. , Herba Artemisiae Scopariae and Radix Glycyrrhizae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Periostracum Cicadae fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, two months is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
1 part of 2 portions of Rhizoma Alismatis of 1 part of Fructus Gardeniae (parched) of Radix Gentianae
2 parts of 2 parts of Radix Sophorae Flavescentiss of 1 part of Cortex Dictamni of the Fructus Kochiae
2 parts of 3 parts of Fructus Forsythiaes of 1 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
1 part of 0.5 part of Rhizoma Polygoni Cuspidati of 3 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
2 parts of 1 portion of Herba Artemisiae Scopariaes of 1 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
Preparation method is to get Periostracum Cicadae drying and crushing to 120~200 order fine powders earlier, get Radix Gentianae again, Fructus Gardeniae (parched), Cortex Dictamni, the Fructus Kochiae, Herba Leonuri, Rhizoma Alismatis, stir-baked CORTEX PHELLODENDRI with salt solution, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Dioscorea septemloba Thunb. , Herba Artemisiae Scopariae and Radix Glycyrrhizae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Periostracum Cicadae fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, two months is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
1 part of 2 portions of Rhizoma Alismatis of 1 part of Fructus Gardeniae (parched) of Radix Gentianae
2 parts of 2 parts of Radix Sophorae Flavescentiss of 1 part of Cortex Dictamni of the Fructus Kochiae
2 parts of 3 parts of Fructus Forsythiaes of 1 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
1 part of 0.5 part of Rhizoma Polygoni Cuspidati of 3 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
2 parts of 1 portion of Herba Artemisiae Scopariaes of 1 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
Preparation method is to get Periostracum Cicadae drying and crushing to 120~200 order fine powders earlier, get Radix Gentianae again, Fructus Gardeniae (parched), Cortex Dictamni, the Fructus Kochiae, Herba Leonuri, Rhizoma Alismatis, stir-baked CORTEX PHELLODENDRI with salt solution, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Dioscorea septemloba Thunb. , Herba Artemisiae Scopariae and Radix Glycyrrhizae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Periostracum Cicadae fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1~3 bag, three to four times on the one, two months is a course of treatment.

Claims (6)

1, a kind of Chinese medicine preparation for the treatment of eczema is characterized in that it is made by the following weight proportion raw material:
0.1~2 part of 1~4 portion of Rhizoma Alismatis of 0.1~2 part of Fructus Gardeniae (parched) of Radix Gentianae
1~4 part of 1~4 part of Radix Sophorae Flavescentis of 0.1~2 part of Cortex Dictamni of the Fructus Kochiae
1~4 part of 1.5~6 parts of Fructus Forsythiae of 0.1~2 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
0.1~2 part of 0.1~1 part of Rhizoma Polygoni Cuspidati of 1.5~6 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1~4 part of 0.1~2 portion of Herba Artemisiae Scopariae of 0.1~2 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
2, a kind of Chinese medicine preparation for the treatment of eczema according to claim 1, wherein the weight proportion of each raw material is:
0.5~1.5 part of 1.5~2.5 portions of Rhizoma Alismatis of 0.5~1.5 part of Fructus Gardeniae (parched) of Radix Gentianae
1.5~2.5 parts of 1.5~2.5 parts of Radix Sophorae Flavescentiss of 0.5~1.5 part of Cortex Dictamni of the Fructus Kochiae
1.5~2.5 parts of 2.5~3.5 parts of Fructus Forsythiaes of 0.5~1.5 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
0.5~1.5 part of 0.3~0.7 part of Rhizoma Polygoni Cuspidati of 2.5~3.5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5~2.5 parts of 0.5~1.5 portion of Herba Artemisiae Scopariaes of 0.5~1.5 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
3, a kind of Chinese medicine preparation for the treatment of eczema according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 portions of Rhizoma Alismatis of 1 part of Fructus Gardeniae (parched) of Radix Gentianae
2 parts of 2 parts of Radix Sophorae Flavescentiss of 1 part of Cortex Dictamni of the Fructus Kochiae
2 parts of 3 parts of Fructus Forsythiaes of 1 part of Herba Leonuri of stir-baked CORTEX PHELLODENDRI with salt solution
1 part of 0.5 part of Rhizoma Polygoni Cuspidati of 3 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
2 parts of 1 portion of Herba Artemisiae Scopariaes of 1 part of Radix Glycyrrhizae of Dioscorea septemloba Thunb. 
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
CNB2006101139515A 2006-10-23 2006-10-23 A Chinese traditional medicinal preparation for treatment of eczema Expired - Fee Related CN100415265C (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101417068B (en) * 2008-11-25 2010-12-22 山西振东制药有限公司 Traditional Chinese medicine bacteriostatic lotion and preparation method thereof
CN101181475B (en) * 2007-11-15 2011-01-26 郭敬春 Chinese medicine composition orally taken for curing acute eczema
CN101199681B (en) * 2007-12-12 2011-05-25 陈德顺 Oral administration Chinese medicine for treating chronicity eczema
CN102370825A (en) * 2011-10-26 2012-03-14 文登市口腔医院 Traditional Chinese medicine for treating eczema
CN102716394A (en) * 2012-06-13 2012-10-10 中国人民解放军总医院 Medicine composition for treating skin diseases
CN102716395A (en) * 2012-06-13 2012-10-10 中国人民解放军总医院 Traditional Chinese medicine spray for treating skin diseases
CN103933397A (en) * 2014-04-22 2014-07-23 湖州康企药业有限公司 Medicine for treating eczema
CN109260405A (en) * 2017-07-13 2019-01-25 张巧英 A kind of health-preserving medicinal liquor medicine vinegar

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181475B (en) * 2007-11-15 2011-01-26 郭敬春 Chinese medicine composition orally taken for curing acute eczema
CN101199681B (en) * 2007-12-12 2011-05-25 陈德顺 Oral administration Chinese medicine for treating chronicity eczema
CN101417068B (en) * 2008-11-25 2010-12-22 山西振东制药有限公司 Traditional Chinese medicine bacteriostatic lotion and preparation method thereof
CN102370825A (en) * 2011-10-26 2012-03-14 文登市口腔医院 Traditional Chinese medicine for treating eczema
CN102370825B (en) * 2011-10-26 2014-01-08 刘运波 Traditional Chinese medicine for treating eczema
CN102716394A (en) * 2012-06-13 2012-10-10 中国人民解放军总医院 Medicine composition for treating skin diseases
CN102716395A (en) * 2012-06-13 2012-10-10 中国人民解放军总医院 Traditional Chinese medicine spray for treating skin diseases
CN102716394B (en) * 2012-06-13 2014-04-02 中国人民解放军总医院 Medicine composition for treating skin diseases
CN102716395B (en) * 2012-06-13 2014-04-23 中国人民解放军总医院 Traditional Chinese medicine spray for treating skin diseases
CN103933397A (en) * 2014-04-22 2014-07-23 湖州康企药业有限公司 Medicine for treating eczema
CN109260405A (en) * 2017-07-13 2019-01-25 张巧英 A kind of health-preserving medicinal liquor medicine vinegar

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