CN1857668A - Chloasma treating Chinese medicine preparation - Google Patents
Chloasma treating Chinese medicine preparation Download PDFInfo
- Publication number
- CN1857668A CN1857668A CN 200610011519 CN200610011519A CN1857668A CN 1857668 A CN1857668 A CN 1857668A CN 200610011519 CN200610011519 CN 200610011519 CN 200610011519 A CN200610011519 A CN 200610011519A CN 1857668 A CN1857668 A CN 1857668A
- Authority
- CN
- China
- Prior art keywords
- parts
- rhizoma
- radix
- chinese medicine
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine preparation for treating chloasma, and the Chinese medicine preparation is prepared with rehmannia root, angelica, red peony, dogwood, burred rhizome and other nine kinds of Chinese medicinal materials. The Chinese medicine preparation has the functions of clearing away heat, purging pathogenic fire, nourishing Yin, increasing body fluid, dispersing the liver depression and promoting blood circulation to disperse blood clots, is used for preventing and treating chloasma, and has the advantages of determined curative effect, no toxic side effect, taking convenience and low cost.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of chloasma, is that a kind of chloasma for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Chloasma be a kind of common face that the increase owing to dermal melanin forms be brown or melanin old property, decrease the dermatosis of capacitive.Chloasma men and women all can be taken place, and is common with blue or green middle-aged women.Be the filbert or black of symmetry, the mottle shape differs, and is distributed in buccal portion more, and other are followed successively by a mouthful week, forehead, nasal side, angle of mandible, geisoma, temples, and individual patient can involve entire face.Being fused into mutually of having is butterfly-like, sharpness of border, and Exposure to Sunlight then increases the weight of.Greater than 9.7%, female patient is about 9: 1 with male patient's ratio to chloasma in some areas crowd nature prevalence, and more up to 28.2%, especially reproduction age, the women was ill more among the adult female.
The traditional Chinese medical science thinks that the morbidity of chloasma is many because deficiency of kidney-QI is general outside its color; Or because of insufficiency of the spleen can not to change spermatogenesis little, deficiency of qi and blood, failure of skin and muscle to be nourished; Or because of deficiency of kidney-essence, essence is not changed blood, can not skin moistening a little less than the blood; Or because of deficiency of kidney yin, give birth in the deficiency-heat, pent-up is not loose, and strongly fragrant in skin, it is not smooth to cause QI-blood circulation, and skin loses supports and the speckle that adds lustre to.The traditional Chinese medical science is dialectical to chloasma, how from liver,spleen,kidney three dirty starting with, also has and starts with dialectically from aspects such as QI and blood, the expectorant stasis of bloods, though the angle difference, substantially similarity all is mark with the blood stasis, and visceral dysfunction is this.Often be divided into that stagnation of liver-QI with deficiency of the spleen, qi depression to blood stasis, blood-deficiency leading to hyperactivity of the liver, deficiency of kidney-YIN, damp invasion of lower energizer, stagnation of QI due to depression of the liver, insufficiency of the spleen blood are weak, stop in the disharmony of Chong and Conception Channels, phlegm-damp, kidney yin sun two loses the disease types such as blood stasis, cold and stagnate of holding concurrently and treats.
Doctor trained in Western medicine thinks that the cause of disease of chloasma is also very not clear and definite, and is main relevant with factors such as endocrine, sunlight, heredity, hepatopathy and tuberculosis, tumor, medicines, and how to be caused by women's gestation, climacteric, oral contraceptive etc.Spirit has substantial connection with primary disease, overtired, have a rest not enough, mental burden is overweight, psychic trauma etc. can cause that pigment deepens.Because etiology unknown is so bring certain difficulty to treatment.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of chloasma, have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radix Paeoniae Rubra of 2.5～10 parts of Radix Angelicae Sinensis of Radix Rehmanniae
0.1～2 part of 0.1～2 part of Rhizoma Curcumae of 0.1～2 part of rhizoma sparganic of Fructus Corni
1.5～6 parts of 1～4 portion of Rhizoma Alismatis of 1.5～6 parts of Poria of Cortex Moutan
1.5～6 parts of 1～4 portion of Rhizoma Dioscoreaes of 0.1～2 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
1～4 part of 0.1～2 part of Rhizoma Anemarrhenae of Rhizoma Chuanxiong
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Paeoniae Rubra of 3～7 parts of Radix Angelicae Sinensis of Radix Rehmanniae
0.5～1.5 part of 0.5～1.5 part of Rhizoma Curcumae of 0.5～1.5 part of rhizoma sparganic of Fructus Corni
2.5～3.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Poria of Cortex Moutan
2.5～3.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 0.5～1.5 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
1.5～2.5 parts of 0.5～1.5 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radix Paeoniae Rubra of 5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Corni
3 parts of 2 portions of Rhizoma Alismatis of 3 parts of Poria of Cortex Moutan
3 parts of 2 portions of Rhizoma Dioscoreaes of 1 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
2 parts of 1 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
Radix Paeoniae Rubra nature and flavor suffering, hardship, flavor are trembled with fear.Return Liver Channel.Has clearing away heat and cooling blood, the effect of eliminating stasis to stop pain.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, traumatic injury, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 659th page).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
The acid of Fructus Corni nature and flavor, puckery, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect of essence astringing and desertion stemming.Can treat have a dizzy spell, seminal emission, dark coloured urine, menorrhagia, soreness of waist and knee joint, tinnitus, hypertension, impotence and premature ejaculation, prolapse of the uterus, sun are taken off, on take off, take off down, frequent micturition, deficiency of the liver cold and heat, interior pyretolysis, incessant sweating due to debility, the heart shake scattered pulse etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 155th page).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, antiearly pregnancy, antineoplastic effect.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Cortex Moutan nature and flavor hardship, suffering, be slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, haematemesis, epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 675th page).
The Poria nature and flavor are sweet, flat, light.GUIXIN, lung, spleen, kidney channel.Has eliminating dampness and diuresis, the effect of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Can treat that dysuria, edema distension, phlegm retention cough with dyspnea, brain are throbbed with fear, have loose bowels in the loose stool, irritability, palpitation with fear, insomnia, forgetful, seminal emission, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) disease, heating do not heal, end empty YANG-depletion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 898th page).
The Rhizoma Alismatis nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Have diuretic, eliminating dampness by diuresis, the effect that expels the heat-evil can be treated dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria etc.(" Chinese medicine voluminous dictionary " the 1461st page).
Radix Arnebiae (Radix Lithospermi) nature and flavor hardship, cold.GUIXIN envelope, Liver Channel.Have removing heat from blood, invigorate blood circulation, the effect of heat-clearing and toxic substances removing.Can treat warm macule, jaundice due to damp-heat, purpura tells, nosebleed, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer etc.(" Chinese medicine voluminous dictionary " the 2344th page).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
The Rhizoma Dioscoreae nature and flavor are sweet, flat.Return spleen, lung, kidney channel.Have the spleen reinforcing nourishing the stomach, the effect of the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Can treat that QI and blood is weak, diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to deficiency of the lung, quench one's thirst, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, diabetes, the enuresis, chronic nephritis, chronic enteritis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 137th page).
Rhizoma Chuanxiong nature and flavor suffering, perfume (or spice).Return liver, gallbladder, pericardium channel.Has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.Can treat menoxenia, amenorrhea dysmenorrhea, difficult labour, stasis of blood resistance pain, lump in the abdomen stomachache, the twinge of the breast side of body, arthralgia due to cold clonic spasm of the muscle, tumbling and swelling, headache due to pathogenic wind-heat, rheumatic arthralgia, skin infection swells and ache, placenta retention, cerebral ischemia, coronary heart disease, angina pectoris, atherosclerosis, hypertension, radiotherapy, leukopenia due to the chemotherapy, juvenile myopia, vitamin e deficiency, flu is dizzy, external plug nose treating malaria disease etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 171st page).
Rhizoma Anemarrhenae nature and flavor hardship, sweet, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.Can treat that fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, tuberculosis heating, cough due to lung-heat, osteopyrexia and fever, interior-heat are quenched one's thirst, the dryness of the intestine constipation, dysuria, diabetes etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 817th page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, rhizoma sparganic, Rhizoma Curcumae, Fructus Corni, Poria and Rhizoma Alismatis, and Radix Bupleuri, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Radix Angelicae Sinensis and Radix Paeoniae Rubra are ministerial drug, and Cortex Moutan, Rhizoma Chuanxiong and Radix Arnebiae (Radix Lithospermi) are adjuvant.All medicines have the effect of clearing away heat-fire, YIN nourishing and the production of body fluid promoting, liver-smoothing, qi-regulating, blood circulation promoting and blood stasis dispelling mutually and altogether, treatment and prevention chloasma, and determined curative effect has no side effect, and taking convenience is cheap.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, peroral dosage form preferably, as: tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the prevention psoriasis of the Chinese medicine of respectively distinguishing the flavor of, and does not have chemical sweeting agent, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and mice is 45g crude drug/kg to the maximum tolerated dose of medicine of the present invention, is 168 times of clinical people's consumption, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat chloasma, and the prevention of chloasma is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment chloasma.
Chloasma curative effect determinate standard (the 224th page of Chen Qin chief editor " research and development of Chinese medicine cosmetic health product " Chinese Medicine science and technology publishing house version in 1999.)
1, cure: facial skin is the normal colour of skin.
2, take a turn for the better: skin disappears more than 30%.
3, do not heal: skin does not have significant change or disappears less than 30%.
As follows through clinical test results; Treatment patient with chloasma 112 examples, male's 14 examples, women's 98 examples, the age is 25～55 years old.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 86 examples and account for 76.7%, 19 examples that take a turn for the better account for 16.9%, and more 7 examples do not account for 6.3%, and total effective rate reaches more than 93%.After three course of therapy, the patient face skin melanin that all has clear improvement disappears in various degree.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Paeoniae Rubra of 5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Corni
3 parts of 2 portions of Rhizoma Alismatis of 3 parts of Poria of Cortex Moutan
3 parts of 2 portions of Rhizoma Dioscoreaes of 1 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
2 parts of 1 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
Preparation method is to get Radix Arnebiae (Radix Lithospermi) drying and crushing to 120～200 order fine powders earlier, get Radix Rehmanniae again, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Fructus Corni, rhizoma sparganic, Rhizoma Curcumae, Cortex Moutan, Poria, Rhizoma Alismatis, Radix Bupleuri, Rhizoma Dioscoreae, the Rhizoma Chuanxiong and the Rhizoma Anemarrhenae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Radix Arnebiae (Radix Lithospermi) fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
3 parts of 3 parts of Radix Paeoniae Rubra of 5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Corni
3 parts of 2 portions of Rhizoma Alismatis of 3 parts of Poria of Cortex Moutan
3 parts of 2 portions of Rhizoma Dioscoreaes of 1 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
2 parts of 1 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
Preparation method is to get Radix Arnebiae (Radix Lithospermi) drying and crushing to 120～200 order fine powders earlier, get Radix Rehmanniae again, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Fructus Corni, rhizoma sparganic, Rhizoma Curcumae, Cortex Moutan, Poria, Rhizoma Alismatis, Radix Bupleuri, Rhizoma Dioscoreae, the Rhizoma Chuanxiong and the Rhizoma Anemarrhenae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Radix Arnebiae (Radix Lithospermi) fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
3 parts of 3 parts of Radix Paeoniae Rubra of 5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Corni
3 parts of 2 portions of Rhizoma Alismatis of 3 parts of Poria of Cortex Moutan
3 parts of 2 portions of Rhizoma Dioscoreaes of 1 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
2 parts of 1 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
Preparation method is to get Radix Arnebiae (Radix Lithospermi) drying and crushing to 120～200 order fine powders earlier, get Radix Rehmanniae again, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Fructus Corni, rhizoma sparganic, Rhizoma Curcumae, Cortex Moutan, Poria, Rhizoma Alismatis, Radix Arnebiae (Radix Lithospermi), Radix Bupleuri, Rhizoma Dioscoreae, the Rhizoma Chuanxiong and the Rhizoma Anemarrhenae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Radix Arnebiae (Radix Lithospermi) fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, one month is a course of treatment.
Claims (6)
1, a kind of Chinese medicine preparation for the treatment of chloasma is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radix Paeoniae Rubra of 2.5～10 parts of Radix Angelicae Sinensis of Radix Rehmanniae
0.1～2 part of 0.1～2 part of Rhizoma Curcumae of 0.1～2 part of rhizoma sparganic of Fructus Corni
1.5～6 parts of 1～4 portion of Rhizoma Alismatis of 1.5～6 parts of Poria of Cortex Moutan
1.5～6 parts of 1～4 portion of Rhizoma Dioscoreaes of 0.1～2 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
1～4 part of 0.1～2 part of Rhizoma Anemarrhenae of Rhizoma Chuanxiong
2, a kind of Chinese medicine preparation for the treatment of chloasma according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Paeoniae Rubra of 3～7 parts of Radix Angelicae Sinensis of Radix Rehmanniae
0.5～1.5 part of 0.5～1.5 part of Rhizoma Curcumae of 0.5～1.5 part of rhizoma sparganic of Fructus Corni
2.5～3.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Poria of Cortex Moutan
2.5～3.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 0.5～1.5 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
1.5～2.5 parts of 0.5～1.5 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
3, a kind of Chinese medicine preparation for the treatment of chloasma according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radix Paeoniae Rubra of 5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Corni
3 parts of 2 portions of Rhizoma Alismatis of 3 parts of Poria of Cortex Moutan
3 parts of 2 portions of Rhizoma Dioscoreaes of 1 part of Radix Bupleuri of Radix Arnebiae (Radix Lithospermi)
2 parts of 1 part of Rhizoma Anemarrhenaes of Rhizoma Chuanxiong
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100115195A CN100496585C (en) | 2006-03-20 | 2006-03-20 | Chloasma treating Chinese medicine preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100115195A CN100496585C (en) | 2006-03-20 | 2006-03-20 | Chloasma treating Chinese medicine preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1857668A true CN1857668A (en) | 2006-11-08 |
| CN100496585C CN100496585C (en) | 2009-06-10 |
Family
ID=37296656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100115195A Expired - Fee Related CN100496585C (en) | 2006-03-20 | 2006-03-20 | Chloasma treating Chinese medicine preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100496585C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101934052A (en) * | 2010-09-04 | 2011-01-05 | 魏玮 | Medicament for treating facial chloasma and preparation method thereof |
| CN102247575A (en) * | 2010-12-21 | 2011-11-23 | 祝凤仪 | Formula and preparation method of liver-soothing and blood circulation-invigorating capsule for treating chloasma |
| CN102430024A (en) * | 2011-11-29 | 2012-05-02 | 青岛阳光海川医药科技发展有限公司 | Traditional Chinese medicine composition, traditional Chinese medicinal preparation and traditional Chinese medicinal face mask |
| CN102895475A (en) * | 2012-10-31 | 2013-01-30 | 延安大学 | Plaster for treating chloasma and preparation method thereof |
| CN104043061A (en) * | 2014-07-06 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating chloasma |
| CN105311344A (en) * | 2015-11-27 | 2016-02-10 | 劳冠阳 | Medicine for treating chloasma |
| CN105686530A (en) * | 2016-03-18 | 2016-06-22 | 宁波高新区苗姑养生科技有限公司 | Health-care pillow capable of moistening dryness and nourishing skin |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247508B (en) * | 2010-12-21 | 2012-07-25 | 祝凤仪 | Capsule for assistant treatment for brown pigment spot, and preparation method thereof |
-
2006
- 2006-03-20 CN CNB2006100115195A patent/CN100496585C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101934052A (en) * | 2010-09-04 | 2011-01-05 | 魏玮 | Medicament for treating facial chloasma and preparation method thereof |
| CN101934052B (en) * | 2010-09-04 | 2011-12-14 | 魏玮 | Medicament for treating facial chloasma and preparation method thereof |
| CN102247575A (en) * | 2010-12-21 | 2011-11-23 | 祝凤仪 | Formula and preparation method of liver-soothing and blood circulation-invigorating capsule for treating chloasma |
| CN102430024A (en) * | 2011-11-29 | 2012-05-02 | 青岛阳光海川医药科技发展有限公司 | Traditional Chinese medicine composition, traditional Chinese medicinal preparation and traditional Chinese medicinal face mask |
| CN102430024B (en) * | 2011-11-29 | 2013-11-06 | 青岛阳光海川医药科技发展有限公司 | Traditional Chinese medicine composition, traditional Chinese medicinal preparation and traditional Chinese medicinal face mask |
| CN102895475A (en) * | 2012-10-31 | 2013-01-30 | 延安大学 | Plaster for treating chloasma and preparation method thereof |
| CN102895475B (en) * | 2012-10-31 | 2014-09-17 | 延安大学 | Plaster for treating chloasma and preparation method thereof |
| CN104043061A (en) * | 2014-07-06 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating chloasma |
| CN105311344A (en) * | 2015-11-27 | 2016-02-10 | 劳冠阳 | Medicine for treating chloasma |
| CN105686530A (en) * | 2016-03-18 | 2016-06-22 | 宁波高新区苗姑养生科技有限公司 | Health-care pillow capable of moistening dryness and nourishing skin |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100496585C (en) | 2009-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100473413C (en) | Chinese medicine preparation for treating senile dementia | |
| CN100496585C (en) | Chloasma treating Chinese medicine preparation | |
| CN1857690A (en) | Gynecopathy treating preparation and its preparing process | |
| CN113827687B (en) | Traditional Chinese medicine formula preparation for treating thyroid nodule and preparation method thereof | |
| CN101028376A (en) | Chinese medicinal preparation for treating habitual abortion | |
| CN102908504B (en) | Chinese medicinal composition for regulating female endocrine dyscrasia | |
| CN102671178B (en) | Preparation method of Chinese medicinal composition for treating nephrotic syndrome and uremia and application thereof | |
| CN103432559A (en) | Traditional Chinese medicine composition for treating spanomenorrhea and dysmenorrhea caused by blood stasis and preparation method and application thereof | |
| CN102343019B (en) | Chinese medicinal composition for treating amenorrhea and preparation method of preparation thereof | |
| CN101618201A (en) | Medicine for curing vulvar leukoplakia | |
| CN103720980A (en) | Medicine for treating chronic nephritis | |
| CN101062335B (en) | Health-care product for removing chloasma | |
| CN100473401C (en) | Chinese medicine preparation for preventing and treating cerebral thrombus and sequel thereof | |
| CN100431584C (en) | Chinese medicinal formulation for caring and enlarging breast | |
| CN101049371A (en) | Chinese medicament for treating barrenness without sperm, and preparation method | |
| CN100431585C (en) | Chinese medicinal formulation for caring and enlarging breast | |
| CN1943766A (en) | A Chinese traditional medicinal preparation for treatment of psoriasis | |
| CN104435641A (en) | Traditional Chinese medicine preparation for treating hyperthyroidism | |
| CN101028362A (en) | Chinese medicine for treating leucoderma | |
| CN100415289C (en) | A Chinese traditional medicinal preparation for treatment of leukoderma | |
| CN101028392B (en) | Chinese medicine for treating hyperlipemia | |
| CN1958006A (en) | Preparation of Chinese traditional medicine for healthy chest and plumpy breasts | |
| CN100473410C (en) | Chinese medicinal preparation for treating apoplexy sequelae | |
| CN101028352A (en) | Chinese-medicinal preparation for treating ischiodynia | |
| CN105521370A (en) | Pharmaceutical preparation for treating colon cancer and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090610 Termination date: 20110320 |