CN101049371A - Chinese medicament for treating barrenness without sperm, and preparation method - Google Patents
Chinese medicament for treating barrenness without sperm, and preparation method Download PDFInfo
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- CN101049371A CN101049371A CN 200710099244 CN200710099244A CN101049371A CN 101049371 A CN101049371 A CN 101049371A CN 200710099244 CN200710099244 CN 200710099244 CN 200710099244 A CN200710099244 A CN 200710099244A CN 101049371 A CN101049371 A CN 101049371A
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Abstract
A Chinese medicine for treating aspermic sterility is prepared from more than 10 Chinese-medicinal materials including astragalus root, pilose asiabell root, rehmannia root, white atractylodes rhizome, etc. Its advantages are sure curative effect, high safety, and no toxic by-effect.
Description
Technical field
The present invention relates to Chinese medicine for the treatment of azoospermia infertility and preparation method thereof, is that a kind of azoospermia infertility for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Sexual intercourse has seminal fluid to penetrate, and smart amount is normal, through the person that all do not find the sperm of semen efamination more than 3 times, is called azoospermia.This disease is the common cause of male sterility, accounts for 19%～30% of male infertility.The azoospermia pathogenic factor is more, and two kinds of situations are arranged substantially: 1, spermatogenesis obstacle, and as congenital deformity of testis, anorchism, cryptorchidism, testis wound, tuberculosis of testis, the concurrent orchitis of mumps, vitamin poorness, edible Semen Gossypii wet goods for a long time.When hypothalamus or hypophysis cerebri endocrine dysfunction, can secondary cause hypoplasia of testis and cause dyszoospermia.As craniocerebral injury or intracranial tumour, make sperm can not discharge promoting sexual gland hormone and secrete androgen, can cause hypoplasia of testis, influence spermatogenesis.2, sperm is carried obstacle, as semen deposition pipeline deformity, congenital lack as, deferent duct wound, inflammation (epididymitis, epididymis, prostate, tuberculosis of seminal vesicle), ejaculatory duct obstruction etc.Above-mentioned reason can not be discharged sperm.The traditional Chinese medical science is thought that the formation of primary disease is many and is not filled because of congenital kidney qi, the natural endowment weakness, and essential substance for reproduction does not have the institute source; Or foster because of losing the day after tomorrow, to lose too, temper is strong, and liver blood does not fill, and essence and blood lacks the source; Also can be because of qi depression to blood stasis, venation is blocked, and smart road is obstructed; Or the testis wound, blood stasis is stagnated, and hinders smart road; Or careless by daily life, cold-damp, damp and hot heresy are gathered in testis, make smart blockage, can not overflow and rush down; Minority is because of mumps, the epidemic disease poison the moon of fainting of making a bet, and the acute orchitis and epididymitis residual poison influences spermatogenesis.Pathology character belongs to deficiency in origin and excess in superficiality, and pathogenesis is that essential substance for reproduction generates not enough and spermatic ejeculation obstacle two aspects.The traditional Chinese medical science is divided into deficiency of kidney-essence clinically, qi depression to blood stasis, and the stagnant heat stopband, the smart road of cold coagulation, disease type Coryza Treated by Syndrome Differentiation such as deficiency of qi and blood obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide Chinese medicine for the treatment of azoospermia infertility and preparation method thereof.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1. 0～4 parts of 1.5～6 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 parts of Radix Codonopsis of Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.0～4 parts of Poria of Radix Rehmanniae Preparata
1.0～4 parts of 1.0～4 parts of Rhizoma Chuanxiongs of 1.0～4 portions of Radix Paeoniae Albas of Fructus Lycii
0.1～2 part of 0.1～2 part of Radix Ginseng of 0.1～2 part of Cortex Eucommiae of Fructus Corni
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 parts of Radix Codonopsis of Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 1.5～2.5 parts of Poria of Radix Rehmanniae Preparata
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Chuanxiongs of 1.5～2.5 portions of Radix Paeoniae Albas of Fructus Lycii
0.5～1.5 part of 0.5～1.5 part of Radix Ginseng of 0.5～1.5 part of Cortex Eucommiae of Fructus Corni
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ginseng property of medicine, tepor.Return lung, spleen, the heart, kidney channel.Have strongly invigorating primordial QI,, promote the production of body fluid, the effect of calming the nerves admittedly take off.Can treat the deficiency of vital energy and desire to take off, impairment caused by overstrain is deficient, and asthenia is indigestion and loss of appetite, vomiting, and the stool lingering diarrhea is breathed hard, spontaneous perspiration, the chronic cough dyspnea due to deficiency is quenched one's thirst, insomnia, palpitation with fear, forgetful, sexual impotence, frequent micturition, the card of all deficiency of vital energy Tianjin wounds such as metrorrhagia etc.(the 42nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali and Radix Codonopsis, is ministerial drug with the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Poria, Radix Angelicae Sinensis, Fructus Lycii, the Radix Paeoniae Alba and Rhizoma Chuanxiong; With Radix Astragali, the Cortex Eucommiae and Radix Ginseng is adjuvant.All medicines are harmonious, and are total to the tool benefiting qi and nourishing blood, the effect of kidney-tonifying and sperm-producing.The treatment azoospermia infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, orally tuck in, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.
Preparation of the present invention, preferably peroral dosage form is as tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment azoospermia infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention treats azoospermia infertility and has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment azoospermia infertility; Treatment azoospermia infertility patient 18 examples.Take embodiment 1 decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.9 examples of fully recovering account for 50%, and 8 examples that take a turn for the better account for 44.44%, and more 1 example does not account for 5.56%, and total effective rate reaches 94.44%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction takes by weighing raw material by following weight:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.Every bag of 210ml, oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules take by weighing raw material by following weight:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
Preparation method is to get above-mentioned raw materials to clean roguing, decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, and the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three months is a course of treatment.
Embodiment 3 tablets take by weighing raw material by following weight:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
Preparation method is to get above-mentioned raw materials to clean roguing, decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, and the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three months is a course of treatment.
Embodiment 4 granules take by weighing raw material by following weight:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
Preparation method is to get above-mentioned raw materials to clean roguing, decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, adds an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, three months is a course of treatment.
Claims (6)
1, Chinese medicine and preparation method thereof of treatment azoospermia infertility is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.5～6 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 parts of Radix Codonopsis of Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.0～4 parts of Poria of Radix Rehmanniae Preparata
1.0～4 parts of 1.0～4 parts of Rhizoma Chuanxiongs of 1.0～4 portions of Radix Paeoniae Albas of Fructus Lycii
0.1～2 part of 0.1～2 part of Radix Ginseng of 0.1～2 part of Cortex Eucommiae of Fructus Corni
2, Chinese medicine of treatment azoospermia infertility according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 parts of Radix Codonopsis of Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 1.5～2.5 parts of Poria of Radix Rehmanniae Preparata
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Chuanxiongs of 1.5～2.5 portions of Radix Paeoniae Albas of Fructus Lycii
0.5～1.5 part of 0.5～1.5 part of Radix Ginseng of 0.5～1.5 part of Cortex Eucommiae of Fructus Corni
3, Chinese medicine of treatment azoospermia infertility according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
2 parts of 3 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Codonopsis of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 2 parts of Poria of Radix Rehmanniae Preparata
2 parts of 2 parts of Rhizoma Chuanxiongs of 2 portions of Radix Paeoniae Albas of Fructus Lycii
1 part of 1 part of Radix Ginseng of 1 part of Cortex Eucommiae of Fructus Corni
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200710099244 CN101049371A (en) | 2007-05-16 | 2007-05-16 | Chinese medicament for treating barrenness without sperm, and preparation method |
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| CN 200710099244 CN101049371A (en) | 2007-05-16 | 2007-05-16 | Chinese medicament for treating barrenness without sperm, and preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727714A (en) * | 2012-07-03 | 2012-10-17 | 许瑞琴 | Traditional Chinese medicinal capsule for treating azoospermia |
| CN105056189A (en) * | 2015-08-20 | 2015-11-18 | 孙涛 | Traditional Chinese medicine for semen non-liquefaction |
| CN108619354A (en) * | 2018-07-06 | 2018-10-09 | 楚雄齐苏堂中医门诊部 | A kind of medicament for tonifying kidney and producing sperm composition and the preparation method and application thereof |
-
2007
- 2007-05-16 CN CN 200710099244 patent/CN101049371A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727714A (en) * | 2012-07-03 | 2012-10-17 | 许瑞琴 | Traditional Chinese medicinal capsule for treating azoospermia |
| CN105056189A (en) * | 2015-08-20 | 2015-11-18 | 孙涛 | Traditional Chinese medicine for semen non-liquefaction |
| CN108619354A (en) * | 2018-07-06 | 2018-10-09 | 楚雄齐苏堂中医门诊部 | A kind of medicament for tonifying kidney and producing sperm composition and the preparation method and application thereof |
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Open date: 20071010 |