CN101085259A - Traditional Chinese medicine decoction for treating chronic nephritis - Google Patents

Abstract

The invention relates to a Chinese medicinal decoction composition for treating chronic nephritis which is prepared from more than ten kinds of Chinese medicinal herbs including prepared rehmannia root, rhizoma dioscoreae, fruit of Chinese wolfberry and herba ecliptae.

Description

The Chinese medicine decoction of treatment chronic nephritis

Technical field

The present invention relates to treat the Chinese medicine decoction of chronic nephritis, is that a kind of chronic nephritis for the treatment of is the Chinese medicine decoction of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

The one group of immune disease that is primary in glomerule that chronic glomerulonephritis (abbreviation chronic nephritis) is made up of multiple reason, multiple histological type.Clinical characters is onset concealment, and the course of disease is tediously long, asymptomatic stage that can be for some time, and routine urianlysis has albuminuria, hematuria and cylinderuria in various degree, and most patient has edema, hypertension and the renal function injury of varying degree.The chronic nephritis sickness rate is higher, is more common in person between twenty and fifty, and the male is more than the women.Along with the development of the state of an illness, the patient can renal failure occur after 2～3 years or 20～30 years, be China's main diseases of causing chronic renal failure because of, account for 64.6%, become the principal disease that influences health of people.Chronic nephritis belongs to categories such as Chinese medicine " edema ", " lumbago ", " headache ", " dizzy ", " asthenia ".Chronic nephritis is clinical to serve as main performance with edema, dizzy, albuminuria, hematuria etc., although clinical manifestation is not quite similar, analyzes with regard to its disease evolution process, and its common etiology and pathogenesis characteristics are all arranged.The clinical manifestation of primary disease is: edema, hypertension, urine abnormal change, renal insufficiency, anemia.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as insufficiency of QI of the lung and kidney, deficiency of spleen-YANG and kidneyYANG, the hepatic and renal YIN deficiency and deficiency of both QI and YIN clinically, obtains very good effect.Chinese medicine not only can alleviate patient's clinical symptoms, and can improve laboratory checking index, can protect and stablize renal function, delays the arrival of renal failure.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine decoction for the treatment of chronic nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Herba Ecliptaes of 1.5～6 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.5～6 parts of Flos Chrysanthemis of Fructus Lycii

0.1～2 part of 1.0～4 parts of Fructus Corni of 1.0～4 portions of Rhizoma Alismatis of Rhizoma Imperatae

0.1～2 part of 1.0～4 parts of Fructus Schisandrae Chinensis of 1.0～4 parts of Folium Pyrrosiaes of Radix Ophiopogonis

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 2.5～3.5 portions of Herba Ecliptaes of 2.5～3.5 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 2.5～3.5 parts of Flos Chrysanthemis of Fructus Lycii

0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 1.5～2.5 portions of Rhizoma Alismatis of Rhizoma Imperatae

0.5～1.5 part of 1.5～2.5 parts of Fructus Schisandrae Chinensis of 1.5～2.5 parts of Folium Pyrrosiaes of Radix Ophiopogonis

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 3 portions of Herba Ecliptaes of 3 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

1 part of 2 parts of Cortex Moutan of 3 parts of Flos Chrysanthemis of Fructus Lycii

1 part of 2 parts of Fructus Corni of 2 portions of Rhizoma Alismatis of Rhizoma Imperatae

1 part of 2 parts of Fructus Schisandrae Chinensis of 2 parts of Folium Pyrrosiaes of Radix Ophiopogonis

Drug action mechanism among the present invention is as follows:

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).

The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Imperatae property of medicine is sweet, and is cold.GUIXIN, lung, stomach, urinary bladder channel.Has clearing away heat and promoting production of body fluid, cooling blood for hemostasis, the effect of inducing diuresis for treating stranguria syndrome.Can treat the calentura excessive thirst, dyspnea and cough due to lung-heat, the gastric heat vomiting, heat in blood is hemorrhage, the puckery pain of dribbling urination, edema, jaundice etc.(the 992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Flos Chrysanthemi property of medicine is sweet, bitter, is slightly cold.Return lung, Liver Channel.Have wind and heat dispersing, suppressing the hyperactive liver makes eye bright, the effect of removing toxic substances and promoting subsidence of swelling.Can treat affection due to external wind and heat or pathogenic wind-warm from the beginning of, fever and headache, dizzy, conjunctival congestion and swelling pain, furuncle swelling toxin etc.(the 2900th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Folium Pyrrosiae property of medicine hardship, sweet, cold.Return lung, kidney, urinary bladder channel.Has relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, the effect of cooling blood for hemostasis.Can treat stranguria, edema, dysuria, the expectorant heat syndrome cough is breathed heavily, and spitting of blood is spitted blood epistaxis, metrorrhagia and traumatic hemorrhage etc.(the 811st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Schisandrae Chinensis property of medicine, warm in nature.Return lung, the heart, kidney channel.It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, the effect of mind tranquilizing and the heart calming.Can treat the chronic cough dyspnea due to deficiency, emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia etc.(the 520th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae Preparata, Rhizoma Dioscoreae and Fructus Lycii; With Rhizoma Imperatae, Radix Ophiopogonis, Flos Chrysanthemi, Rhizoma Alismatis, Folium Pyrrosiae and Herba Ecliptae is ministerial drug; With Cortex Moutan, Fructus Corni and Fructus Schisandrae Chinensis is adjuvant.All medicines are harmonious, and are total to the tool nourishing the liver and kidney, the effect of hemostasia and detumescence.The treatment chronic nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment chronic nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat chronic nephritis, and the prevention of chronic nephritis is also had good effect, and the treatment chronic nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chronic nephritis; Treatment chronic nephritis patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.9 examples of fully recovering account for 45%, and 9 examples that take a turn for the better account for 45%, and more 2 examples do not account for 10%, and total effective rate reaches 90%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 3 portions of Herba Ecliptaes of 3 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

1 part of 2 parts of Cortex Moutan of 3 parts of Flos Chrysanthemis of Fructus Lycii

1 part of 2 parts of Fructus Corni of 2 portions of Rhizoma Alismatis of Rhizoma Imperatae

1 part of 2 parts of Fructus Schisandrae Chinensis of 2 parts of Folium Pyrrosiaes of Radix Ophiopogonis.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chronic nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine decoction of treatment chronic nephritis is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Herba Ecliptaes of 1.5～6 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.5～6 parts of Flos Chrysanthemis of Fructus Lycii

0.1～2 part of 1.0～4 parts of Fructus Corni of 1.0～4 portions of Rhizoma Alismatis of Rhizoma Imperatae

0.1～2 part of 1.0～4 parts of Fructus Schisandrae Chinensis of 1.0～4 parts of Folium Pyrrosiaes of Radix Ophiopogonis.

2, the Chinese medicine decoction of treatment chronic nephritis according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 2.5～3.5 portions of Herba Ecliptaes of 2.5～3.5 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 2.5～3.5 parts of Flos Chrysanthemis of Fructus Lycii

0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 1.5～2.5 portions of Rhizoma Alismatis of Rhizoma Imperatae

0.5～1.5 part of 1.5～2.5 parts of Fructus Schisandrae Chinensis of 1.5～2.5 parts of Folium Pyrrosiaes of Radix Ophiopogonis.

3, the Chinese medicine decoction of treatment chronic nephritis according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 3 portions of Herba Ecliptaes of 3 portions of Rhizoma Dioscoreaes of Radix Rehmanniae Preparata

1 part of 2 parts of Cortex Moutan of 3 parts of Flos Chrysanthemis of Fructus Lycii

1 part of 2 parts of Fructus Corni of 2 portions of Rhizoma Alismatis of Rhizoma Imperatae

1 part of 2 parts of Fructus Schisandrae Chinensis of 2 parts of Folium Pyrrosiaes of Radix Ophiopogonis.