CN101095829A - Chinese traditional medicine preparations for treating diabetes constipation - Google Patents
Chinese traditional medicine preparations for treating diabetes constipation Download PDFInfo
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- CN101095829A CN101095829A CNA2007101183419A CN200710118341A CN101095829A CN 101095829 A CN101095829 A CN 101095829A CN A2007101183419 A CNA2007101183419 A CN A2007101183419A CN 200710118341 A CN200710118341 A CN 200710118341A CN 101095829 A CN101095829 A CN 101095829A
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Abstract
The invention relates to a Chinese medicament for treating diabetic constipation, which is prepared from more than ten kinds of Chinese medicinal herbs including achyranthes and cyathula root, spicebush root, immature bitter orange and ophiopogon root. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetic constipation, is that a kind of diabetic constipation for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic constipation is one of diabetes common complication, and sickness rate is 10%~20%.Pathological changes is in the clinical manifestation of large intestine based on constipation.Diabetic constipation has " difficulty in defecation " in Chinese medicine, " not defecating ", " no defecation ", " stercoroma ", titles such as " spleen-constipation ".Can be summarized as by its cause of disease and pathogenesis: excess syndrome of YANG MING FU-organ, dry stool accumulating in the intestine (functional constipation); Liver temper is strongly fragrant, and (constipation due to disorder of QI) etc. do not fall in the gas of lung stomach is the constipation of excess type card.Asthenia of pulmonosplenic qi, big enteroparesis (constipation due to insufficiency); Deficiency of spleen-YANG and kidneyYANG transmits unable (constipation due to accumulation of pathogenic cold); Blood deficiency is cloudy loses, and intestinal mistake profit (constipation due to insufficiency) etc. are the constipation due to insufficiency card.
The constipation that the constipation of deficiency of both the splenic and pulmonary QI and blood deficiency the moon lose all is called " constipation due to insufficiency " at gold dollar period, comprises blood deficiency and constipation and constipation due to deficiency of QI, is cloudy Tianjin of intestinal and deficiency of YIN-blood, and intestinal loses profit, and it is descending difficult to defecate; Constipation due to deficiency of QI is the large intestine muscular flaccidity, transmits unablely, belongs to the deficiency syndrome category.In a word, the traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as functional constipation, constipation due to disorder of QI, constipation due to insufficiency and constipation due to accumulation of pathogenic cold clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 portions of Radix Scrophulariaes of 1.5~6 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1.0~4 parts of 1.0~4 parts of Radix Paeoniae Rubra of 1.0~4 parts of Radix Ophiopogonis of Fructus Cannabis
1.0~4 parts of 1.0~4 parts of Fructus Aurantii Immaturuss of 1.0~4 portions of Radix Cyathulaes of Radix Polygoni Multiflori
0.1~2 part of 0.1~2 part of Radix Linderae of 0.1~2 part of Semen Persicae of Radix Et Rhizoma Rhei.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 portions of Radix Scrophulariaes of 2.5~3.5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1.5~2.5 parts of 1.5~2.5 parts of Radix Paeoniae Rubra of 1.5~2.5 parts of Radix Ophiopogonis of Fructus Cannabis
1.5~2.5 parts of 1.5~2.5 parts of Fructus Aurantii Immaturuss of 1.5~2.5 portions of Radix Cyathulaes of Radix Polygoni Multiflori
0.5~1.5 part of 0.5~1.5 part of Radix Linderae of 0.5~1.5 part of Semen Persicae of Radix Et Rhizoma Rhei.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 portions of Radix Scrophulariaes of 3 parts of Radix Angelicae Sinensis of Radix Rehmanniae
2 parts of 2 parts of Radix Paeoniae Rubra of 2 parts of Radix Ophiopogonis of Fructus Cannabis
2 parts of 2 parts of Fructus Aurantii Immaturuss of 2 portions of Radix Cyathulaes of Radix Polygoni Multiflori
1 part of 1 part of Radix Linderae of 1 part of Semen Persicae of Radix Et Rhizoma Rhei.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Cannabis nature and flavor are sweet, and are flat.Return spleen, stomach, large intestine channel.Effect with loosening bowel to relieve constipation.Can treat blood deficiency and depleted fluid, dryness of the intestine constipation etc.(the 60th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii Immaturus property of medicine hardship, suffering are slightly cold.Return spleen, stomach, large intestine channel.Have the dispelling the stagnated QI removing food stagnancy, reduce phlegm except that the effect of painful abdominal mass.Can treat and stop in stagnant, the feeling of fullness distending pain, constipation, heavy behind the dysentery, blocked-up chest, the thoracic obstruction, gastroptosis, uterine prolapse, proctoptosis etc.(the 2231st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Linderae property of medicine suffering, temperature.Return spleen, stomach, liver, kidney, urinary bladder channel.Have promoting the circulation of QI to relieve pain, the effect of warming kidney for dispelling cold.It is vexed to treat fullness in the chest and hypochondrium, abdominal distention, headache, colic of cold type pain, dysmenorrhea and puerperal abdonimal pain, frequent micturition, the enuresis etc.(the 655th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, Radix Angelicae Sinensis and Radix Scrophulariae; With Fructus Cannabis, Radix Ophiopogonis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, Radix Cyathulae and Fructus Aurantii Immaturus is ministerial drug; With Radix Et Rhizoma Rhei, Semen Persicae and the Radix Linderae is adjuvant.All medicines are harmonious, tool enriching blood for moistening the intestine altogether, the effect of relieving constipation by purgation.The treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic constipation, and the prevention of diabetic constipation is also had good effect, and the treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic constipation; Treatment diabetic constipation patient 23 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 43.48%, and 9 examples that take a turn for the better account for 39.13%, and invalid 4 examples account for 17.39%, and total effective rate reaches 82.61%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 portions of Radix Scrophulariaes of 3 parts of Radix Angelicae Sinensis of Radix Rehmanniae
2 parts of 2 parts of Radix Paeoniae Rubra of 2 parts of Radix Ophiopogonis of Fructus Cannabis
2 parts of 2 parts of Fructus Aurantii Immaturuss of 2 portions of Radix Cyathulaes of Radix Polygoni Multiflori
1 part of 1 part of Radix Linderae of 1 part of Semen Persicae of Radix Et Rhizoma Rhei.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic constipation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of diabetic constipation is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 portions of Radix Scrophulariaes of 1.5~6 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1.0~4 parts of 1.0~4 parts of Radix Paeoniae Rubra of 1.0~4 parts of Radix Ophiopogonis of Fructus Cannabis
1.0~4 parts of 1.0~4 parts of Fructus Aurantii Immaturuss of 1.0~4 portions of Radix Cyathulaes of Radix Polygoni Multiflori
0.1~2 part of 0.1~2 part of Radix Linderae of 0.1~2 part of Semen Persicae of Radix Et Rhizoma Rhei.
2, a kind of Chinese medicine preparation for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 portions of Radix Scrophulariaes of 2.5~3.5 parts of Radix Angelicae Sinensis of Radix Rehmanniae
1.5~2.5 parts of 1.5~2.5 parts of Radix Paeoniae Rubra of 1.5~2.5 parts of Radix Ophiopogonis of Fructus Cannabis
1.5~2.5 parts of 1.5~2.5 parts of Fructus Aurantii Immaturuss of 1.5~2.5 portions of Radix Cyathulaes of Radix Polygoni Multiflori
0.5~1.5 part of 0.5~1.5 part of Radix Linderae of 0.5~1.5 part of Semen Persicae of Radix Et Rhizoma Rhei.
3, a kind of Chinese medicine preparation for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 portions of Radix Scrophulariaes of 3 parts of Radix Angelicae Sinensis of Radix Rehmanniae
2 parts of 2 parts of Radix Paeoniae Rubra of 2 parts of Radix Ophiopogonis of Fructus Cannabis
2 parts of 2 parts of Fructus Aurantii Immaturuss of 2 portions of Radix Cyathulaes of Radix Polygoni Multiflori
1 part of 1 part of Radix Linderae of 1 part of Semen Persicae of Radix Et Rhizoma Rhei.
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CNA2007101183419A CN101095829A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating diabetes constipation |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101554426B (en) * | 2008-04-09 | 2011-04-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic obstipation |
CN101628056B (en) * | 2009-08-05 | 2011-04-20 | 刘志美 | Compound composition for treating diabetic constipation |
CN104983980A (en) * | 2015-07-10 | 2015-10-21 | 宋云飞 | Traditional Chinese medicine for treating diabetic coprostasis |
-
2007
- 2007-07-05 CN CNA2007101183419A patent/CN101095829A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101554426B (en) * | 2008-04-09 | 2011-04-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic obstipation |
CN101628056B (en) * | 2009-08-05 | 2011-04-20 | 刘志美 | Compound composition for treating diabetic constipation |
CN104983980A (en) * | 2015-07-10 | 2015-10-21 | 宋云飞 | Traditional Chinese medicine for treating diabetic coprostasis |
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Open date: 20080102 |