CN101095749A - Chinese patent drug for treating diabetic constipation - Google Patents
Chinese patent drug for treating diabetic constipation Download PDFInfo
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- CN101095749A CN101095749A CNA2007101183438A CN200710118343A CN101095749A CN 101095749 A CN101095749 A CN 101095749A CN A2007101183438 A CNA2007101183438 A CN A2007101183438A CN 200710118343 A CN200710118343 A CN 200710118343A CN 101095749 A CN101095749 A CN 101095749A
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Abstract
The invention relates to a Chinese medicament for treating diabetic constipation which is prepared from more than ten kinds of Chinese medicinal herbs including Chinese angelica root, fleece-flower root, ligustrum japonicum and sesame seed. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of diabetic constipation, is that a kind of diabetic constipation for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic constipation is one of diabetes common complication, and sickness rate is 10%～20%.Pathological changes is in the clinical manifestation of large intestine based on constipation.Diabetic constipation has " difficulty in defecation " in Chinese medicine, " not defecating ", " no defecation ", " stercoroma ", titles such as " spleen-constipation ".Can be summarized as by its cause of disease and pathogenesis: excess syndrome of YANG MING FU-organ, dry stool accumulating in the intestine (functional constipation); Liver temper is strongly fragrant, and (constipation due to disorder of QI) etc. do not fall in the gas of lung stomach is the constipation of excess type card.Asthenia of pulmonosplenic qi, big enteroparesis (constipation due to insufficiency); Deficiency of spleen-YANG and kidneyYANG transmits unable (constipation due to accumulation of pathogenic cold); Blood deficiency is cloudy loses, and intestinal mistake profit (constipation due to insufficiency) etc. are the constipation due to insufficiency card.
The constipation that the constipation of deficiency of both the splenic and pulmonary QI and blood deficiency the moon lose all is called " constipation due to insufficiency " at gold dollar period, comprises blood deficiency and constipation and constipation due to deficiency of QI, is cloudy Tianjin of intestinal and deficiency of YIN-blood, and intestinal loses profit, and it is descending difficult to defecate; Constipation due to deficiency of QI is the large intestine muscular flaccidity, transmits unablely, belongs to the deficiency syndrome category.In a word, the traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as functional constipation, constipation due to disorder of QI, constipation due to insufficiency and constipation due to accumulation of pathogenic cold clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of diabetic constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Fructus Trichosanthis of 1.5～6 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
1.0～4 parts of 1.0～4 parts of Fructus Ligustri Lucidi of 1.0～4 parts of Radix Polygoni Multiflori of Radix Rehmanniae
1.0～4 parts of 1.0～4 parts of Cortex Mori of 1.0～4 portions of Radix Scrophulariaes of Herba Cistanches
0.1～2 part of 0.1～2 part of Semen Platycladi of 0.1～2 part of Semen Pruni of Fructus Cannabis.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Fructus Trichosanthis of 2.5～3.5 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
1.5～2.5 parts of 1.5～2.5 parts of Fructus Ligustri Lucidi of 1.5～2.5 parts of Radix Polygoni Multiflori of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 parts of Cortex Mori of 1.5～2.5 portions of Radix Scrophulariaes of Herba Cistanches
0.5～1.5 part of 0.5～1.5 part of Semen Platycladi of 0.5～1.5 part of Semen Pruni of Fructus Cannabis.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Fructus Trichosanthis of 3 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
2 parts of 2 parts of Fructus Ligustri Lucidi of 2 parts of Radix Polygoni Multiflori of Radix Rehmanniae
2 parts of 2 parts of Cortex Mori of 2 portions of Radix Scrophulariaes of Herba Cistanches
1 part of 1 part of Semen Platycladi of 1 part of Semen Pruni of Fructus Cannabis.
Drug action mechanism among the present invention is as follows;
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Sesami Nigrum property of medicine is sweet, and property is flat.Return the liver,spleen,kidney warp.Effect with nourish blood benefit essence, loosening bowel to relieve constipation.Can treat the dizziness and tinnitus due to the Liver and kidney asthenia of essence and blood, waist foot flaccidity is soft, early whitening of beard and hair, and scaly dry skin, the dryness of the intestine constipation, married woman's breast is few, carbuncle skin ulcer eczema, wind leprosy scrofula infections, infantile scrofula, burn, hemorrhoid etc.(the 3338th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Fructus Trichosanthis property of medicine, cold.Return lung, stomach, large intestine channel.Has the heat clearing away expectorant, relieving stuffiness of the chest by dispersing aggregation of pathogens, the effect of moisturizing laxation.Can treat pulmonary carcinoma, gastric cancer, cancer of pancreas, breast carcinoma etc.It is thick to be used for the turbid Huang of cough due to lung-heat's expectorant, obstruction of qi in the chest and cardialgia, and the blocked-up chest feeling of fullness, acute mastitis, lung abscess, acute appendicitis swells and ache, constipation etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 483rd page).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Cistanches property of medicine is sweet, salty, temperature.Return kidney, large intestine channel.Has kidney-replenishing, benefiting essence-blood, the effect in intestine moistening road.Can treat the sexual impotence of kidney yang deficiency, asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, the lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation etc.(the 1226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Cortex Mori nature and flavor are sweet, hot, and are cold.Return lung, spleen channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Cure mainly the fullness in the chest that lung-heat or diseases caused by retention of fluid stop lung and breath with cough hemoptysis, edema, beriberi, dysuria etc.(the 2787th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Cannabis nature and flavor are sweet, and are flat.Return spleen, stomach, large intestine channel.Effect with loosening bowel to relieve constipation.Can treat blood deficiency and depleted fluid, dryness of the intestine constipation etc.(the 60th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Semen Pruni property of medicine suffering, hardship, sweet, flat.Return spleen, large intestine, small intestine meridian.Has intestine moistening treatment constipation, the effect of therapeutic method to keep the adverse QI flowing downwards diuretic.Can treat the dryness of the intestine constipation, dysuria, edema abdominal distention, beriberi etc.(the 1858th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Platycladi property of medicine is sweet, and is flat.GUIXIN, kidney, large intestine channel.Has tranquilizing by nourishing the heart, arresting sweating, the effect of loosening bowel to relieve constipation.Can treat the palpitation with fear palpitation with a distress feeling, insomnia forgetfulness, night sweat, dryness of the intestine constipation etc.(the 2238th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, Semen Sesami Nigrum and Fructus Trichosanthis; With Radix Rehmanniae, Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Herba Cistanches, Radix Scrophulariae and Cortex Mori is ministerial drug; With Fructus Cannabis, Semen Pruni and Semen Platycladi is adjuvant.All medicines are harmonious, and are total to the tool nourishing the liver and kidney, the effect of loosening bowel to relieve constipation.The treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic constipation, and the prevention of diabetic constipation is also had good effect, and the treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic constipation; Treatment diabetic constipation patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 40%, and 9 examples that take a turn for the better account for 45%, and invalid 3 examples account for 15%, and total effective rate reaches 85%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Fructus Trichosanthis of 3 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
2 parts of 2 parts of Fructus Ligustri Lucidi of 2 parts of Radix Polygoni Multiflori of Radix Rehmanniae
2 parts of 2 parts of Cortex Mori of 2 portions of Radix Scrophulariaes of Herba Cistanches
1 part of 1 part of Semen Platycladi of 1 part of Semen Pruni of Fructus Cannabis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic constipation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese patent medicine for the treatment of diabetic constipation is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Fructus Trichosanthis of 1.5～6 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
1.0～4 parts of 1.0～4 parts of Fructus Ligustri Lucidi of 1.0～4 parts of Radix Polygoni Multiflori of Radix Rehmanniae
1.0～4 parts of 1.0～4 parts of Cortex Mori of 1.0～4 portions of Radix Scrophulariaes of Herba Cistanches
0.1～2 part of 0.1～2 part of Semen Platycladi of 0.1～2 part of Semen Pruni of Fructus Cannabis.
2, a kind of Chinese patent medicine for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Fructus Trichosanthis of 2.5～3.5 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
1.5～2.5 parts of 1.5～2.5 parts of Fructus Ligustri Lucidi of 1.5～2.5 parts of Radix Polygoni Multiflori of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 parts of Cortex Mori of 1.5～2.5 portions of Radix Scrophulariaes of Herba Cistanches
0.5～1.5 part of 0.5～1.5 part of Semen Platycladi of 0.5～1.5 part of Semen Pruni of Fructus Cannabis.
3, a kind of Chinese patent medicine for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Fructus Trichosanthis of 3 portions of Semen Sesami Nigrums of Radix Angelicae Sinensis
2 parts of 2 parts of Fructus Ligustri Lucidi of 2 parts of Radix Polygoni Multiflori of Radix Rehmanniae
2 parts of 2 parts of Cortex Mori of 2 portions of Radix Scrophulariaes of Herba Cistanches
1 part of 1 part of Semen Platycladi of 1 part of Semen Pruni of Fructus Cannabis.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101183438A CN101095749A (en) | 2007-07-05 | 2007-07-05 | Chinese patent drug for treating diabetic constipation |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101183438A CN101095749A (en) | 2007-07-05 | 2007-07-05 | Chinese patent drug for treating diabetic constipation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101518591B (en) * | 2008-02-27 | 2011-02-09 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic constipation |
| CN103404670A (en) * | 2013-08-28 | 2013-11-27 | 北京绿源求证科技发展有限责任公司 | Health tea dissolved medicines for dietary therapy of constipation |
-
2007
- 2007-07-05 CN CNA2007101183438A patent/CN101095749A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101518591B (en) * | 2008-02-27 | 2011-02-09 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic constipation |
| CN103404670A (en) * | 2013-08-28 | 2013-11-27 | 北京绿源求证科技发展有限责任公司 | Health tea dissolved medicines for dietary therapy of constipation |
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Open date: 20080102 |