CN101095816A - Chinese traditional medicine preparations for treating diabetic neurogenic bladder - Google Patents
Chinese traditional medicine preparations for treating diabetic neurogenic bladder Download PDFInfo
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- CN101095816A CN101095816A CNA2007101183461A CN200710118346A CN101095816A CN 101095816 A CN101095816 A CN 101095816A CN A2007101183461 A CNA2007101183461 A CN A2007101183461A CN 200710118346 A CN200710118346 A CN 200710118346A CN 101095816 A CN101095816 A CN 101095816A
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Abstract
The invention relates to a Chinese medicament for treating diabetic neurogenic bladder which is prepared from more than ten kinds of Chinese medicinal herbs including oyster shell, poria cocos, herba ecliptae and ligustrum japonicum thumb. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to treat the Chinese medicine preparation of diabetic neurogenic bladder, is that a kind of diabetic neurogenic bladder for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic neurogenic bladder is meant the maincenter of bladder or the urinary dysfunction that peripheral neuropathy causes, is called neurogenic bladder, is called cord bladder, nervous bladder functional disorder or atonic bladder again.The sickness rate of diabetic neurogenic bladder is 27%～85%.Because dysuria, easily cause the intractable urinary tract infection, increase the weight of diabetes so that influence renal function, be one of reason of diabetics death.According to the urine leaching glass not to the utmost, it is similar to " stranguria ", " difficulty in urination " in the Chinese medicine to urinate puckery symptom such as unfavorable.Pouring is meant that frequent micturition is short puckery, the sound of rain pattering not to the utmost, urethra is unfavorable, the cramp and pain in the lower abdomen person." Elementary Medicine ": " drench, whether difficulty and pain in micturition desired to go or not, and do not go to come again, drips constantly." can be divided into stranguria caused by urinary stone according to different performances clinically, qi stranguria, stranguria with blood, stranguria marked by chyluria, five kinds of strangurias caused by overstrain etc. are generically and collectively referred to as " five types of stranguria ".The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine preparation for the treatment of diabetic neurogenic bladder.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 portions of Rhizoma Alismatis of 1.5～6 parts of Poria of Concha Ostreae (calcined)
1.0～4 parts of 1.0～4 parts of Rhizoma Anemarrhenaes of 1.0～4 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
0.1～2 part of 1.0～4 portions of Semen Euryales of 1.0～4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.1～2 part of 0.1～2 portion of Herba Dianthi of 0.1～2 portion of Cortex Phellodendri of Cortex Moutan.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Poria of Concha Ostreae (calcined)
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Anemarrhenaes of 1.5～2.5 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 portions of Semen Euryales of 1.5～2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.5～1.5 part of 0.5～1.5 portion of Herba Dianthi of 0.5～1.5 portion of Cortex Phellodendri of Cortex Moutan.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 portions of Rhizoma Alismatis of 3 parts of Poria of Concha Ostreae (calcined)
2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
1 part of 2 portions of Semen Euryales of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Herba Dianthi of 1 portion of Cortex Phellodendri of Cortex Moutan.
Drug action mechanism among the present invention is as follows:
The Concha Ostreae (calcined) property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Euryales property of medicine is sweet, puckery, and is flat.Return spleen, kidney channel.Has reinforcing the kindey to control nocturnal emission, spleen reinforcing antidiarrheal effect.Can treat seminal emission, nebulousurine, leukorrhagia, incontinence of urine, loose stool and diarrhea etc.(the 1492nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Dianthi property of medicine hardship, cold.GUIXIN, liver, small intestinal, urinary bladder channel.Has diuresis, clearing away damp-heat, the effect of promoting blood circulation to restore menstrual flow.Can treat urinary obstruction, pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, amenorrhea, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus, eczema pruritus etc.(the 3816th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Concha Ostreae (calcined), Poria and Rhizoma Alismatis; With Radix Rehmanniae, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Fructus Ligustri Lucidi, Herba Ecliptae and Semen Euryales is ministerial drug; With Cortex Moutan, Cortex Phellodendri and the Rhizoma Anemarrhenae is adjuvant.All medicines are harmonious, tool nourishing YIN and supplementing the kidney altogether, the effect of clearing heat and freeing strangury.The treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic neurogenic bladder of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic neurogenic bladder, and the prevention of diabetic neurogenic bladder is also had good effect, and the treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic neurogenic bladder; Treatment diabetic neurogenic bladder underwent 22 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 45.45%, and 9 examples that take a turn for the better account for 40.91%, and invalid 3 examples account for 13.64%, and total effective rate reaches 86.36%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 portions of Rhizoma Alismatis of 3 parts of Poria of Concha Ostreae (calcined)
2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
1 part of 2 portions of Semen Euryales of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Herba Dianthi of 1 portion of Cortex Phellodendri of Cortex Moutan.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic neurogenic bladder that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, the Chinese medicine preparation of treatment diabetic neurogenic bladder is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 portions of Rhizoma Alismatis of 1.5～6 parts of Poria of Concha Ostreae (calcined)
1.0～4 parts of 1.0～4 parts of Rhizoma Anemarrhenaes of 1.0～4 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
0.1～2 part of 1.0～4 portions of Semen Euryales of 1.0～4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.1～2 part of 0.1～2 portion of Herba Dianthi of 0.1～2 portion of Cortex Phellodendri of Cortex Moutan.
2, the Chinese medicine preparation of treatment diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Poria of Concha Ostreae (calcined)
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Anemarrhenaes of 1.5～2.5 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 portions of Semen Euryales of 1.5～2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.5～1.5 part of 0.5～1.5 portion of Herba Dianthi of 0.5～1.5 portion of Cortex Phellodendri of Cortex Moutan.
3, the Chinese medicine preparation of treatment diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 portions of Rhizoma Alismatis of 3 parts of Poria of Concha Ostreae (calcined)
2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 portions of Rhizoma Dioscoreaes of Radix Rehmanniae
1 part of 2 portions of Semen Euryales of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Herba Dianthi of 1 portion of Cortex Phellodendri of Cortex Moutan.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183461A CN101095816A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating diabetic neurogenic bladder |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183461A CN101095816A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating diabetic neurogenic bladder |
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| Publication Number | Publication Date |
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| CN101095816A true CN101095816A (en) | 2008-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2007101183461A Pending CN101095816A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating diabetic neurogenic bladder |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526547A (en) * | 2012-01-11 | 2012-07-04 | 廉波 | Medicine for treating diabetic bladder disease |
| CN103007229A (en) * | 2012-12-27 | 2013-04-03 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN104971211A (en) * | 2014-04-02 | 2015-10-14 | 王嘉影 | Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease |
-
2007
- 2007-07-05 CN CNA2007101183461A patent/CN101095816A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526547A (en) * | 2012-01-11 | 2012-07-04 | 廉波 | Medicine for treating diabetic bladder disease |
| CN103007229A (en) * | 2012-12-27 | 2013-04-03 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN103007229B (en) * | 2012-12-27 | 2013-11-27 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN104971211A (en) * | 2014-04-02 | 2015-10-14 | 王嘉影 | Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease |
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Open date: 20080102 |