CN101129766A - Chinese medicine preparation for treating constipation - Google Patents

Chinese medicine preparation for treating constipation Download PDF

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Publication number
CN101129766A
CN101129766A CNA2007101223238A CN200710122323A CN101129766A CN 101129766 A CN101129766 A CN 101129766A CN A2007101223238 A CNA2007101223238 A CN A2007101223238A CN 200710122323 A CN200710122323 A CN 200710122323A CN 101129766 A CN101129766 A CN 101129766A
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radix
semen
constipation
chinese medicine
parts
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CNA2007101223238A
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101223238A priority Critical patent/CN101129766A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating constipation which is prepared from more than ten kinds of Chinese medicinal herbs including Chinese angelica root, ophiopogon root, asparagus root and root of herbaceous peony. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine preparation for the treatment of constipation
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of constipation, is that a kind of to treat constipation be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Constipation system is because of deficiency of both vital energy and Yin, or dryness-heat stagnating in the interior, and due to internal organs gas was not smooth, with the infrequent defecation time lengthening, constipation with dry stool was difficult to resolve the disease into main clinical manifestation.Often refer to habitual constipation.Primary disease can betide any age patient, and young and middle-aged sickness rate is about 1%~5%, and old people's sickness rate both had been found in the process of multiple disease up to 15%~30%, can independently occur again, also is physical work minimizing or long-term bed patient's common complication.
Constipation traditional Chinese medical science title at all times is a lot, " difficulty in defecation ", " back is unfavorable ", " spleen-constipation ", " constipation caused by accumulation of heat ", " constipation of YIN type ", " intestinal knot ", " constipation due to pathogenic wind ", " functional constipation ", " wind-dryness ", " heat is dry ", " constipation due to insufficiency " etc. is arranged, existing general designation " constipation ".
Chinese medicine think constipation be a variety of causes cause the large intestine conduction function not normal due to, its reason has: 1, large intestine dryness-heat stagnating in the interior.2, depression and stagnation of QI.3, qi-blood-body fluid is lost empty.4, year is high weak.The sick position of primary disease is at large intestine, and is relevant with lung, liver,spleen,kidney.So the traditional Chinese medical science is divided into the deficiency and excess two ends in dialectical treatment, with sthenia syndrome requiring purgation, deficiency syndrome should be treated by tonifying method is the rule of treatment; Constipation of excess type is divided into: functional constipation, constipation due to disorder of QI.Constipation due to insufficiency is divided into: the deficiency of vital energy is secret, hematasthenic constipation, suffer from a deficiency of the kidney secret, the deficiency of YIN is secret.Chronic constipation is a kind of commonly encountered diseases of digestive system.Since constipation repeatedly or continue outbreak, bring very big misery to the patient, influence people's live and work, even can bring out or increase the weight of old people's cardiovascular and cerebrovascular disease and cause intestinal obstruction, threat to life safety.Though in recent years the pathogenesis of primary disease is studied, think with defecation adynamia, spastic colon, the rectum defecation reflex is blunt or forfeiture, autonomous defecation reflex weaken, encysted rectum etc. is relevant, but western medicine, takes stopgap measures and does not effect a permanent cure mainly based on the clothes cathartic the treatment primary disease.Even up-to-date short digestive tract power reinforcing medicine cisapride, the curative effect of its treatment constipation is also not fully up to expectations.
The Chinese medicine constipation not only has superiority aspect relieving constipation, and in constipation relieving, disorderly gastrointestinal function obtains adjusting, and patient's physical condition is improved.Because tcm clinical efficacy is good, toxic and side effects is little, is accepted by the patient easily.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 parts of Fructus Cannabis of 1.0~4 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
0.1~2 part of 0.1~2 part of Radix Et Rhizoma Rhei of 1.0~4 portions of Radix Paeoniae Albas of Radix Asparagi
0.1~2 part of 0.1~2 part of Semen Platycladi of 1.0~4 parts of Semen Persicaes of Semen Trichosanthis
0.1~2 part of 0.1~2 part of Semen Pruni of 1.0~4 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 parts of Fructus Cannabis of 1.5~2.5 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
0.5~1.5 part of 0.5~1.5 part of Radix Et Rhizoma Rhei of 1.5~2.5 portions of Radix Paeoniae Albas of Radix Asparagi
0.5~1.5 part of 0.5~1.5 part of Semen Platycladi of 1.5~2.5 parts of Semen Persicaes of Semen Trichosanthis
0.5~1.5 part of 0.5~1.5 part of Semen Pruni of 1.5~2.5 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 2 parts of Fructus Cannabis of 2 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
1 part of 1 part of Radix Et Rhizoma Rhei of 2 portions of Radix Paeoniae Albas of Radix Asparagi
1 part of 1 part of Semen Platycladi of 2 parts of Semen Persicaes of Semen Trichosanthis
1 part of 1 part of Semen Pruni of 2 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Asparagi property of medicine is sweet, bitter, and is cold.Return lung, kidney channel.Have nourshing Yin and drynsessmoistening prescription, the effect of lung heat clearing pathogenic fire reducing.Can treat cough caused by dryness-heat, deficiency of YIN chronic cough, consumption of YIN caused by febrile disease, interior-heat is quenched one's thirst, dryness of the intestine constipation, laryngopharynx swelling and pain etc.(the 435th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Trichosanthis nature and flavor are sweet, and are cold.Return lung, stomach, large intestine channel.Has moistening the lung and resolving phlegm, the effect of laxation relieving constipation.It is glutinous to treat cough caused by dryness expectorant, dryness of the intestine constipation etc.(the 85th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Cannabis property of medicine is sweet, and is flat.Return spleen, stomach, large intestine channel.Has the laxation of moisturizing, diuretic, the effect of invigorating blood circulation.Can treat the dryness of the intestine constipation, migratory arthralgia is quenched one's thirst, edema due to wind pathogen, beriberi, pyretic stranguria, dysentery, menoxenia, skin ulcer tinea, erysipelas etc.(the 696th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Platycladi property of medicine is sweet, and is flat.GUIXIN, kidney, large intestine channel.Has tranquilizing by nourishing the heart, arresting sweating, the effect of loosening bowel to relieve constipation.Can treat the palpitation with fear palpitation with a distress feeling, insomnia forgetfulness, night sweat, dryness of the intestine constipation etc.(the 2238th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Pruni property of medicine suffering, hardship, sweet, flat.Return spleen, large intestine, small intestine meridian.Has loosening bowel to relieve constipation, the effect of therapeutic method to keep the adverse QI flowing downwards diuretic.Can treat the dryness of the intestine constipation, dysuria, edema abdominal distention, beriberi etc.(the 1858th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, the Rhizoma Anemarrhenae and Fructus Cannabis; With Radix Ophiopogonis, Radix Asparagi, Semen Trichosanthis, Radix Et Rhizoma Rhei, Semen Platycladi and Semen Pruni is ministerial drug; With the Radix Paeoniae Alba, Semen Persicae and Radix Scrophulariae is adjuvant.All medicines are harmonious, and are total to the tool nourishing YIN to lower pathogenic fire, the effect of loosening bowel to relieve constipation.The treatment constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat constipation, and the prevention of constipation is also had good effect, and the treatment constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment constipation; Treatment constipation patient 24 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two weeks is a course of treatment, take continuously three the course of treatment observe the curative effect.17 examples of fully recovering account for 70.83%, and 5 examples that take a turn for the better account for 20.83%, and more 2 examples do not account for 8.33%, and total effective rate reaches 91.66%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
1 part of 2 parts of Fructus Cannabis of 2 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
1 part of 1 part of Radix Et Rhizoma Rhei of 2 portions of Radix Paeoniae Albas of Radix Asparagi
1 part of 1 part of Semen Platycladi of 2 parts of Semen Persicaes of Semen Trichosanthis
1 part of 1 part of Semen Pruni of 2 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment constipation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two weeks is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of constipation is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 parts of Fructus Cannabis of 1.0~4 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
0.1~2 part of 0.1~2 part of Radix Et Rhizoma Rhei of 1.0~4 portions of Radix Paeoniae Albas of Radix Asparagi
0.1~2 part of 0.1~2 part of Semen Platycladi of 1.0~4 parts of Semen Persicaes of Semen Trichosanthis
0.1~2 part of 0.1~2 part of Semen Pruni of 1.0~4 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
2. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 1.5~2.5 parts of Fructus Cannabis of 1.5~2.5 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
0.5~1.5 part of 0.5~1.5 part of Radix Et Rhizoma Rhei of 1.5~2.5 portions of Radix Paeoniae Albas of Radix Asparagi
0.5~1.5 part of 0.5~1.5 part of Semen Platycladi of 1.5~2.5 parts of Semen Persicaes of Semen Trichosanthis
0.5~1.5 part of 0.5~1.5 part of Semen Pruni of 1.5~2.5 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
3. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 2 parts of Fructus Cannabis of 2 parts of Rhizoma Anemarrhenaes of Radix Ophiopogonis
1 part of 1 part of Radix Et Rhizoma Rhei of 2 portions of Radix Paeoniae Albas of Radix Asparagi
1 part of 1 part of Semen Platycladi of 2 parts of Semen Persicaes of Semen Fructus Trichosanthis
1 part of 1 part of Semen Pruni of 2 portions of Radix Scrophulariaes of Radix Angelicae Sinensis.
CNA2007101223238A 2007-09-24 2007-09-24 Chinese medicine preparation for treating constipation Pending CN101129766A (en)

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Application Number Priority Date Filing Date Title
CNA2007101223238A CN101129766A (en) 2007-09-24 2007-09-24 Chinese medicine preparation for treating constipation

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103478366A (en) * 2013-10-09 2014-01-01 北京绿源求证科技发展有限责任公司 Health-preserving tea soluble granule for diet therapy of constipation
CN103948780A (en) * 2014-04-23 2014-07-30 通化万通药业股份有限公司 Medicine and capsule for treating constipation
CN103960662A (en) * 2014-05-09 2014-08-06 深圳市皇都御颜养生科技有限责任公司 Method for preparing health-care food with effect of facilitating feces excretion
CN104491530A (en) * 2014-12-16 2015-04-08 济南方宇文化传媒有限公司 Granule for treating constipation caused by bowel dysfunction and preparation method thereof
CN104784282A (en) * 2014-01-20 2015-07-22 中国中医科学院中药研究所 Traditional Chinese medicinal compound preparation for treating constipation
CN109394962A (en) * 2018-12-04 2019-03-01 俞傲然 A kind of drug for treating constipation

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103478366A (en) * 2013-10-09 2014-01-01 北京绿源求证科技发展有限责任公司 Health-preserving tea soluble granule for diet therapy of constipation
CN104784282A (en) * 2014-01-20 2015-07-22 中国中医科学院中药研究所 Traditional Chinese medicinal compound preparation for treating constipation
CN103948780A (en) * 2014-04-23 2014-07-30 通化万通药业股份有限公司 Medicine and capsule for treating constipation
CN103960662A (en) * 2014-05-09 2014-08-06 深圳市皇都御颜养生科技有限责任公司 Method for preparing health-care food with effect of facilitating feces excretion
CN104491530A (en) * 2014-12-16 2015-04-08 济南方宇文化传媒有限公司 Granule for treating constipation caused by bowel dysfunction and preparation method thereof
CN109394962A (en) * 2018-12-04 2019-03-01 俞傲然 A kind of drug for treating constipation

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Open date: 20080227