CN101085281A - Traditional Chinese medicine for curing chronic nephritis - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating chronic nephritis, which is prepared from more than ten kinds of Chinese medicinal herbs including achyranthes and cyathula root, corn stigma, motherwort fruit and oriental water plantain rhizome.

Description

A kind of Chinese medicine of treatment chronic nephritis

Technical field

The present invention relates to treat a kind of Chinese medicine of chronic nephritis, is that a kind of chronic nephritis for the treatment of is the Chinese medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

The one group of immune disease that is primary in glomerule that chronic glomerulonephritis (abbreviation chronic nephritis) is made up of multiple reason, multiple histological type.Clinical characters is onset concealment, and the course of disease is tediously long, asymptomatic stage that can be for some time, and routine urianlysis has albuminuria, hematuria and cylinderuria in various degree, and most patient has edema, hypertension and the renal function injury of varying degree.The chronic nephritis sickness rate is higher, is more common in person between twenty and fifty, and the male is more than the women.Along with the development of the state of an illness, the patient can renal failure occur after 2～3 years or 20～30 years, be China's main diseases of causing chronic renal failure because of, account for 64.6%, become the principal disease that influences health of people.Chronic nephritis belongs to categories such as Chinese medicine " edema ", " lumbago ", " headache ", " dizzy ", " asthenia ".Chronic nephritis is clinical to serve as main performance with edema, dizzy, albuminuria, hematuria etc., although clinical manifestation is not quite similar, analyzes with regard to its disease evolution process, and its common etiology and pathogenesis characteristics are all arranged.The clinical manifestation of primary disease is: edema, hypertension, urine abnormal change, renal insufficiency, anemia.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as insufficiency of QI of the lung and kidney, deficiency of spleen-YANG and kidneyYANG, the hepatic and renal YIN deficiency and deficiency of both QI and YIN clinically, obtains very good effect.Chinese medicine not only can alleviate patient's clinical symptoms, and can improve laboratory checking index, can protect and stablize renal function, delays the arrival of renal failure.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine for the treatment of chronic nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 2.5～10 parts of Radix Astragali of Stigma Maydis

0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Radix Angelicae Sinensis of Radix Cyathulae

0.1～2 part of 1.0～4 parts of Rhizoma Curcumae of 1.0～4 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Radix Paeoniae Rubra of Herba Leonuri.

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 4.5～5.5 parts of Radix Astragali of Stigma Maydis

0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Radix Angelicae Sinensis of Radix Cyathulae

0.5～1.5 part of 1.5～2.5 parts of Rhizoma Curcumae of 1.5～2.5 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Radix Paeoniae Rubra of Herba Leonuri.

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 2 portions of Rhizoma Alismatis of 5 parts of Radix Astragali of Stigma Maydis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Angelicae Sinensis of Radix Cyathulae

1 part of 2 parts of Rhizoma Curcumae of 2 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Paeoniae Rubra of Herba Leonuri.

Drug action mechanism among the present invention is as follows:

The Stigma Maydis property of medicine is sweet, light, and is flat.Return kidney, stomach, liver, gallbladder meridian.Has inducing diuresis to remove edema, the effect of liver heat removing function of gallbladder promoting.Can treat edema, stranguria, nebulousurine is quenched one's thirst, jaundice, cholecystitis, cholelithiasis, hypertension, acute mastitis, galactostasis etc.(the 777th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).

Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with rhizoma sparganic, Rhizoma Curcumae and Radix Cyathulae; With Radix Angelicae Sinensis, Radix Rehmanniae, Rhizoma Chuanxiong, Herba Leonuri, Radix Astragali and Rhizoma Alismatis is ministerial drug; With Radix Bupleuri, Radix Paeoniae Rubra and Stigma Maydis is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of inducing diuresis to remove edema.The treatment chronic nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment chronic nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat chronic nephritis, and the prevention of chronic nephritis is also had good effect, and the treatment chronic nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chronic nephritis; Treatment chronic nephritis patient 19 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 36.84%, and 9 examples that take a turn for the better account for 47.37%, and more 3 examples do not account for 15.79%, and total effective rate reaches 84.21%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 2 portions of Rhizoma Alismatis of 5 parts of Radix Astragali of Stigma Maydis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Angelicae Sinensis of Radix Cyathulae

1 part of 2 parts of Rhizoma Curcumae of 2 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Paeoniae Rubra of Herba Leonuri.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chronic nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine of treatment chronic nephritis is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 2.5～10 parts of Radix Astragali of Stigma Maydis

0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Radix Angelicae Sinensis of Radix Cyathulae

0.1～2 part of 1.0～4 parts of Rhizoma Curcumae of 1.0～4 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Radix Paeoniae Rubra of Herba Leonuri.

2, a kind of Chinese medicine of treatment chronic nephritis according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 4.5～5.5 parts of Radix Astragali of Stigma Maydis

0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Radix Angelicae Sinensis of Radix Cyathulae

0.5～1.5 part of 1.5～2.5 parts of Rhizoma Curcumae of 1.5～2.5 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Radix Paeoniae Rubra of Herba Leonuri.

3, a kind of Chinese medicine of treatment chronic nephritis according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 portions of Rhizoma Alismatis of 5 parts of Radix Astragali of Stigma Maydis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Angelicae Sinensis of Radix Cyathulae

1 part of 2 parts of Rhizoma Curcumae of 2 parts of Rhizoma Chuanxiongs of Radix Rehmanniae

1 part of 2 parts of Radix Bupleuri of 2 parts of Radix Paeoniae Rubra of Herba Leonuri.