CN101095922A - Chinese traditional medicine composition for treating diabetes peripheral neuritis - Google Patents

Chinese traditional medicine composition for treating diabetes peripheral neuritis Download PDF

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Publication number
CN101095922A
CN101095922A CNA2007101184144A CN200710118414A CN101095922A CN 101095922 A CN101095922 A CN 101095922A CN A2007101184144 A CNA2007101184144 A CN A2007101184144A CN 200710118414 A CN200710118414 A CN 200710118414A CN 101095922 A CN101095922 A CN 101095922A
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CN
China
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radix
parts
rhizoma
chinese medicine
peripheral neuritis
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CNA2007101184144A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101184144A priority Critical patent/CN101095922A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating diabetic peripheral neuritis, which is prepared from more than ten kinds of Chinese medicinal herbs including achyranthes and cyathula root, banksia rose, chuanxiong rhizome and frank incense. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine composition for the treatment of diabetes peripheral neuritis
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of diabetes peripheral neuritis, is that a kind of diabetes peripheral neuritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic peripheral neuropathy is more common in above middle age, and the dissatisfied or course of disease of diabetes control is than the elder.Small number of patients is first symptom with neuropathy.What the most common and symptom early occurred is the lower limb pathological changes.The diabetic neuropathy complicated clinical, its sorting technique is multiple, does not reach an agreement as yet.For ease of clinical observation, so classify in conjunction with lesion nature by diseased region.Peripheral neuropathy claims the peripheral nerve sexually transmitted disease (STD) to become again.Be divided into multiple neuropathy of symmetry and the multiple mononeuropathy change of asymmetry by its clinical manifestation.Wherein the multiple neuropathy of symmetry also comprises: far-end symmetry sensory nerve pathological changes, symmetry nervus motorius pathological changes; Asymmetry polyneuropathy and mononeuropathy are mainly due to the nerve trunk vasa vasorum blood supply insufficiency.According to the clinical manifestation of multiple neuropathy, " arthromyodynia " of the suitable traditional Chinese medical science, " pain card ", " myopathy " scope.Primary disease system is because of the diabetes obstinate disease, and prolonged illness must be empty, and consumption is hindered healthy energy, causes insufficiency of vital energy and blood, incoordination between nutrient QI and defensive QI, and collaterals being void and defenceless, QI-blood circulation is not smooth." Lei Zheng Zhi Cai ": " all coagulation of QI-blood form numbness for a long time." just recognize " greatly through inanition " as far back as ancient times, and recognize that the generation of myopathy and diseases of five ZANG-organs in a disguised form close.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of vital energy arthralgia due to stagnation of blood, Liver and kidney two void, insufficiency of the spleen stagnation of phlegm, stasis of blood resistance venation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetes peripheral neuritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Myrrha of 1.5~6 parts of rhizoma sparganic of Radix Rehmanniae
0.1~2 part of 1.0~4 portions of Radix Curcumae of 1.5~6 parts of Rhizoma Curcumae of Radix Cyathulae
0.1~2 part of 0.1~2 part of Radix Aucklandiae of 1.0~4 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.1~2 part of 0.1~2 part of Pheretima of 1.0~4 parts of Olibanums of Radix Paeoniae Rubra.
The weight proportion of each raw material of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 parts of Myrrha of 2.5~3.5 parts of rhizoma sparganic of Radix Rehmanniae
0.5~1.5 part of 1.5~2.5 portions of Radix Curcumae of 2.5~3.5 parts of Rhizoma Curcumae of Radix Cyathulae
0.5~1.5 part of 0.5~1.5 part of Radix Aucklandiae of 1.5~2.5 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.5~1.5 part of 0.5~1.5 part of Pheretima of 1.5~2.5 parts of Olibanums of Radix Paeoniae Rubra.
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 parts of Myrrha of 3 parts of rhizoma sparganic of Radix Rehmanniae
1 part of 2 portions of Radix Curcumae of 3 parts of Rhizoma Curcumae of Radix Cyathulae
1 part of 1 part of Radix Aucklandiae of 2 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 1 part of Pheretima of 2 parts of Olibanums of Radix Paeoniae Rubra.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Olibanum property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Have and invigorate blood circulation, circulation of qi promoting, analgesic effect.Can treat trusted subordinate's pain, amenorrhea, dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, traumatic injury stasis of blood pain, swollen ulcer drug, the sore being festered and unhealed etc.(the 1992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Myrrha property of medicine hardship, flat.GUIXIN, liver, spleen channel.Has blood stasis dispelling, detumescence, the effect of analgesic therapy.Can treat breast stomachache, dysmenorrhea, amenorrhea , mass in the abdomen, treating swelling and pain by traumatic injury, carbuncle skin infection, conjunctival congestion and swelling pain etc.(the 1636th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea , mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aucklandiae property of medicine suffering, hardship, temperature.Return spleen, stomach, liver, lung meridian.Have promoting the circulation of QI to relieve pain, the effect of mediation intestinal stasis relieving.Can treat fullness and distention in the chest and hypochondrium, abdominal distention, vomiting is had loose bowels, and heavily waits after the dysentery.(the 480th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Pheretima nature and flavor are salty, cold.Go into liver, spleen, lung, urinary bladder channel.Have heat clearing away, suppressing the hyperactive liver, Zhichuan, collateral dredging diuretic effect.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pant, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection, hyperpyrexia, bronchial asthma, hypertension, psychosis, ulcer of the lower limb, eczema, erysipelas, burn and scald, fracture etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 522nd page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Olibanum, Myrrha, Radix Rehmanniae and Radix Cyathulae; With Radix Angelicae Sinensis, Radix Paeoniae Rubra, rhizoma sparganic, Rhizoma Curcumae and Pheretima is ministerial drug; With Rhizoma Chuanxiong, Radix Curcumae and the Radix Aucklandiae is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of removing obstruction in the collateral to relieve pain.The treatment diabetes peripheral neuritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetes peripheral neuritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetes peripheral neuritis, and the prevention of diabetes peripheral neuritis is also had good effect, and the treatment diabetes peripheral neuritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetes peripheral neuritis; Treatment diabetes peripheral neuritis patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 38.89%, and 8 examples that take a turn for the better account for 44.44%, and invalid 3 examples account for 16.67%, and total effective rate reaches 83.33%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 2 parts of Myrrha of 3 parts of rhizoma sparganic of Radix Rehmanniae
1 part of 2 portions of Radix Curcumae of 3 parts of Rhizoma Curcumae of Radix Cyathulae
1 part of 1 part of Radix Aucklandiae of 2 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 1 part of Pheretima of 2 parts of Olibanums of Radix Paeoniae Rubra.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetes peripheral neuritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of diabetes peripheral neuritis is characterized in that it is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Myrrha of 1.5~6 parts of rhizoma sparganic of Radix Rehmanniae
0.1~2 part of 1.0~4 portions of Radix Curcumae of 1.5~6 parts of Rhizoma Curcumae of Radix Cyathulae
0.1~2 part of 0.1~2 part of Radix Aucklandiae of 1.0~4 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.1~2 part of 0.1~2 part of Pheretima of 1.0~4 parts of Olibanums of Radix Paeoniae Rubra.
2, a kind of Chinese medicine composition for the treatment of diabetes peripheral neuritis according to claim 1, wherein the weight proportion of each raw material is:
0.5~1.5 part of 1.5~2.5 parts of Myrrha of 2.5~3.5 parts of rhizoma sparganic of Radix Rehmanniae
0.5~1.5 part of 1.5~2.5 portions of Radix Curcumae of 2.5~3.5 parts of Rhizoma Curcumae of Radix Cyathulae
0.5~1.5 part of 0.5~1.5 part of Radix Aucklandiae of 1.5~2.5 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.5~1.5 part of 0.5~1.5 part of Pheretima of 1.5~2.5 parts of Olibanums of Radix Paeoniae Rubra.
3, a kind of Chinese medicine composition for the treatment of diabetes peripheral neuritis according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 parts of Myrrha of 3 parts of rhizoma sparganic of Radix Rehmanniae
1 part of 2 portions of Radix Curcumae of 3 parts of Rhizoma Curcumae of Radix Cyathulae
1 part of 1 part of Radix Aucklandiae of 2 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 1 part of Pheretima of 2 parts of Olibanums of Radix Paeoniae Rubra.
CNA2007101184144A 2007-07-05 2007-07-05 Chinese traditional medicine composition for treating diabetes peripheral neuritis Pending CN101095922A (en)

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Application Number Priority Date Filing Date Title
CNA2007101184144A CN101095922A (en) 2007-07-05 2007-07-05 Chinese traditional medicine composition for treating diabetes peripheral neuritis

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CN101095922A true CN101095922A (en) 2008-01-02

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103251916A (en) * 2013-05-21 2013-08-21 徐笑群 Chinese herb preparation for treating peripheral neuritis
CN105250569A (en) * 2015-11-26 2016-01-20 王茂凯 Traditional Chinese medicine pill for treating peripheral neuritis and preparation method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103251916A (en) * 2013-05-21 2013-08-21 徐笑群 Chinese herb preparation for treating peripheral neuritis
CN103251916B (en) * 2013-05-21 2014-11-05 徐笑群 Chinese herb preparation for treating peripheral neuritis
CN105250569A (en) * 2015-11-26 2016-01-20 王茂凯 Traditional Chinese medicine pill for treating peripheral neuritis and preparation method

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Open date: 20080102