CN101129723A - Chinese medicine preparation for treating constipation - Google Patents

Chinese medicine preparation for treating constipation Download PDF

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Publication number
CN101129723A
CN101129723A CNA2007101223276A CN200710122327A CN101129723A CN 101129723 A CN101129723 A CN 101129723A CN A2007101223276 A CNA2007101223276 A CN A2007101223276A CN 200710122327 A CN200710122327 A CN 200710122327A CN 101129723 A CN101129723 A CN 101129723A
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parts
radix
constipation
chinese medicine
medicine preparation
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CNA2007101223276A
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101223276A priority Critical patent/CN101129723A/en
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Abstract

The invention relates to a Chinese medicinal preparation for treating constipation which is prepared from more than ten kinds of Chinese medicinal herbs including rhubarb horsetails, immature bitter orange, bark of peony root and aloe. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine preparation of treatment constipation
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of constipation, is that a kind of to treat constipation be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Constipation system is because of deficiency of both vital energy and Yin, or dryness-heat stagnating in the interior, and due to internal organs gas was not smooth, with the infrequent defecation time lengthening, constipation with dry stool was difficult to resolve the disease into main clinical manifestation.Often refer to habitual constipation.Primary disease can betide any age patient, and young and middle-aged sickness rate is about 1%~5%, and old people's sickness rate both had been found in the process of multiple disease up to 15%~30%, can independently occur again, also is physical work minimizing or long-term bed patient's common complication.
Constipation traditional Chinese medical science title at all times is a lot, " difficulty in defecation ", " back is unfavorable ", " spleen-constipation ", " constipation caused by accumulation of heat ", " constipation of YIN type ", " intestinal knot ", " constipation due to pathogenic wind ", " functional constipation ", " wind-dryness ", " heat is dry ", " constipation due to insufficiency " etc. is arranged, existing general designation " constipation ".
Chinese medicine think constipation be a variety of causes cause the large intestine conduction function not normal due to, its reason has: 1, large intestine dryness-heat stagnating in the interior.2, depression and stagnation of QI.3, qi-blood-body fluid is lost empty.4, year is high weak.The sick position of primary disease is at large intestine, and is relevant with lung, liver,spleen,kidney.So the traditional Chinese medical science is divided into the deficiency and excess two ends in dialectical treatment, with sthenia syndrome requiring purgation, deficiency syndrome should be treated by tonifying method is the rule of treatment; Constipation of excess type is divided into: functional constipation, constipation due to disorder of QI.Constipation due to insufficiency is divided into: the deficiency of vital energy is secret, hematasthenic constipation, suffer from a deficiency of the kidney secret, the deficiency of YIN is secret.Chronic constipation is a kind of commonly encountered diseases of digestive system.Since constipation repeatedly or continue outbreak, bring very big misery to the patient, influence people's live and work, even can bring out or increase the weight of old people's cardiovascular and cerebrovascular disease and cause intestinal obstruction, threat to life safety.Though in recent years the pathogenesis of primary disease is studied, think with defecation adynamia, spastic colon, the rectum defecation reflex is blunt or forfeiture, autonomous defecation reflex weaken, encysted rectum etc. is relevant, but western medicine, takes stopgap measures and does not effect a permanent cure mainly based on the clothes cathartic the treatment primary disease.Even up-to-date short digestive tract power reinforcing medicine cisapride, the curative effect of its treatment constipation is also not fully up to expectations.
The Chinese medicine constipation not only has superiority aspect relieving constipation, and in constipation relieving, disorderly gastrointestinal function obtains adjusting, and patient's physical condition is improved.Because tcm clinical efficacy is good, toxic and side effects is little, is accepted by the patient easily.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.7~3 part of 0.7~3 part of Cortex Magnoliae Officinalis of 1.0~4 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
0.7~3 part of 0.7~3 part of Radix Ophiopogonis of 1.0~4 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
0.1~2 part of 0.7~3 part of Semen Raphani of 1.0~4 parts of Radix Angelicae Sinensis of Semen Arecae
0.1~2 part of 0.7~3 part of Cortex Moutan of 0.1~2 portion of Radix Scrophulariae of Aloe.
The weight proportion of each crude drug of optimization formula of the present invention is:
1.0~2.0 parts of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
1.0~2.0 parts of 1.0~2.0 parts of Radix Ophiopogonis of 1.5~2.5 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
0.5~1.5 part of 1.0~2.0 parts of Semen Raphani of 1.5~2.5 parts of Radix Angelicae Sinensis of Semen Arecae
0.5~1.5 part of 1.0~2.0 parts of Cortex Moutan of 0.5~1.5 portion of Radix Scrophulariae of Aloe.
The weight proportion of each crude drug of optimum formula of the present invention is:
1.5 parts of 1.5 parts of Cortex Magnoliae Officinalis of 2 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
1.5 parts of 1.5 parts of Radix Ophiopogonis of 2 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
1 part of 1.5 parts of Semen Raphani of 2 parts of Radix Angelicae Sinensis of Semen Arecae
1 part of 1.5 parts of Cortex Moutan of 1 portion of Radix Scrophulariae of Aloe.
Drug action mechanism among the present invention is as follows:
The Fructus Cannabis property of medicine is sweet, and is flat.Return spleen, stomach, large intestine channel.Has the laxation of moisturizing, diuretic, the effect of invigorating blood circulation.Can treat the dryness of the intestine constipation, migratory arthralgia is quenched one's thirst, edema due to wind pathogen, beriberi, pyretic stranguria, dysentery, menoxenia, skin ulcer tinea, erysipelas etc.(the 696th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Arecae nature and flavor hardship, suffering, temperature.Return stomach, large intestine channel.Has killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, the effect of preventing the attack (or recurrence) of malaria.Can treat cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria etc.(the 300th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Fructus Aurantii Immaturus property of medicine hardship, suffering are slightly cold.Return spleen, stomach, large intestine channel.Have the dispelling the stagnated QI removing food stagnancy, reduce phlegm except that the effect of painful abdominal mass.Can treat and stop in stagnant, the feeling of fullness distending pain, constipation, heavy behind the dysentery, blocked-up chest, the thoracic obstruction, gastroptosis, uterine prolapse, proctoptosis etc.(the 2231st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Natrii Sulfas nature and flavor are salty, bitter, and are cold.Return stomach, large intestine channel.Has purging heat to relax the bowels, moistening for dryness and softening hard mass, the repercussive effect of relieving inflammation or internal heat.Can treat the excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; The external treatment acute mastitis, swelling and pain of hemorrhoid etc.(the 96th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Magnoliae Officinalis property of medicine hardship, suffering, temperature.Return stomach, large intestine channel.Has the circulation of qi promoting intestinal stasis relieving, dampness, the effect of lowering the adverse QI to relieve asthma.Can treat stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough etc.(the 2284th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Raphani property of medicine suffering, sweet, flat.Return spleen, stomach, lung, large intestine channel.Has dyspepsia and intestinal stasis relieving, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy behind the dysentery, cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Aloe property of medicine hardship, cold.Return liver, large intestine channel.Have and rush down down liver heat removing, parasiticidal effect.Can treat constipation with heat retention, liver-fire headache, conjunctival congestion infantile convulsion, abdominal pain due to worm stagnation, scabies, hemorrhoid complicated by anal fistula etc.(the 1499th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Fructus Cannabis, Radix Et Rhizoma Rhei and Semen Arecae; With Fructus Aurantii Immaturus, Natrii Sulfas, Radix Angelicae Sinensis, Radix Scrophulariae, Cortex Magnoliae Officinalis and Radix Ophiopogonis is ministerial drug; With Semen Raphani, Cortex Moutan and Aloe is adjuvant.All medicines are harmonious, and are total to the tool cooling intestine to eliminate heat, the effect of loosening bowel to relieve constipation.The treatment constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat constipation, and the prevention of constipation is also had good effect, and the treatment constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment constipation; Treatment constipation patient 35 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two weeks is a course of treatment, take continuously three the course of treatment observe the curative effect.26 examples of fully recovering account for 74.29%, and 8 examples that take a turn for the better account for 22.86%, and more 1 example does not account for 2.85%, and total effective rate reaches 97.15%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
1.5 parts of 1.5 parts of Cortex Magnoliae Officinalis of 2 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
1.5 parts of 1.5 parts of Radix Ophiopogonis of 2 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
1 part of 1.5 parts of Semen Raphani of 2 parts of Radix Angelicae Sinensis of Semen Arecae
1 part of 1.5 parts of Cortex Moutan of 1 portion of Radix Scrophulariae of Aloe.
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment constipation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two weeks is a course of treatment.

Claims (3)

1. a kind of Chinese medicine preparation of treatment constipation is characterized in that it is made by following raw materials by weight proportions:
0.7~3 part of 0.7~3 part of Cortex Magnoliae Officinalis of 1.0~4 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
0.7~3 part of 0.7~3 part of Radix Ophiopogonis of 1.0~4 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
0.1~2 part of 0.7~3 part of Semen Raphani of 1.0~4 parts of Radix Angelicae Sinensis of Semen Arecae
0.1~2 part of 0.7~3 part of Cortex Moutan of 0.1~2 portion of Radix Scrophulariae of Aloe.
2. a kind of Chinese medicine preparation of treatment constipation according to claim 1, wherein the weight proportion of each crude drug is:
1.0~2.0 parts of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
1.0~2.0 parts of 1.0~2.0 parts of Radix Ophiopogonis of 1.5~2.5 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
0.5~1.5 part of 1.0~2.0 parts of Semen Raphani of 1.5~2.5 parts of Radix Angelicae Sinensis of Semen Arecae
0.5~1.5 part of 1.0~2.0 parts of Cortex Moutan of 0.5~1.5 portion of Radix Scrophulariae of Aloe.
3. a kind of Chinese medicine preparation of treatment constipation according to claim 1, wherein the weight proportion of each crude drug is:
1.5 parts of 1.5 parts of Cortex Magnoliae Officinalis of 2 parts of Fructus Aurantii Immaturuss of Fructus Cannabis
1.5 parts of 1.5 parts of Radix Ophiopogonis of 2 parts of Natrii Sulfas of Radix Et Rhizoma Rhei
1 part of 1.5 parts of Semen Raphani of 2 parts of Radix Angelicae Sinensis of Semen Arecae
1 part of 1.5 parts of Cortex Moutan of 1 portion of Radix Scrophulariae of Aloe.
CNA2007101223276A 2007-09-24 2007-09-24 Chinese medicine preparation for treating constipation Pending CN101129723A (en)

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101293066B (en) * 2008-06-18 2010-09-22 周鑫 Umbilicus plastering powder for defaecation
CN102188522A (en) * 2011-04-29 2011-09-21 陕西白鹿制药股份有限公司 Traditional Chinese medicine composition for treating constipation
CN102416111A (en) * 2011-11-26 2012-04-18 王少云 Chinese medicinal composition for treating cattle cotton cake positioning and preparation method thereof
CN103251046A (en) * 2012-04-23 2013-08-21 乔德京 Health food for enhancing immunity
CN103405635A (en) * 2013-08-30 2013-11-27 石欣 Traditional Chinese medicine composition for treating middle and old aged constipation
CN103877540A (en) * 2014-03-06 2014-06-25 魏伟 Traditional Chinese medicine for treating caesarean section postoperation false intestinal obstruction and preparation method thereof
CN104146241A (en) * 2013-12-19 2014-11-19 河南茗轩食品科技有限公司 Health composition capable of benefiting bodies and relaxing bowels and preparation method of health composition
CN105232854A (en) * 2015-11-26 2016-01-13 河南中医学院 Traditional Chinese medicine pill treating empirical constipation
CN105343512A (en) * 2015-12-16 2016-02-24 齐鲁工业大学 Traditional Chinese medicine composition for treating constipation and preparation method thereof
CN104587016B (en) * 2015-01-13 2017-06-16 河南省洛阳正骨医院河南省骨科医院 A kind of Chinese traditional medicine navel patch and preparation method for treating constipation
CN108079152A (en) * 2018-01-16 2018-05-29 暨南大学 A kind of Chinese prescription for being used for digestive system function obstacle and inflammation
CN112076170A (en) * 2020-08-20 2020-12-15 浙江康乐药业股份有限公司 Tablet with function of relaxing bowels

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101293066B (en) * 2008-06-18 2010-09-22 周鑫 Umbilicus plastering powder for defaecation
CN102188522A (en) * 2011-04-29 2011-09-21 陕西白鹿制药股份有限公司 Traditional Chinese medicine composition for treating constipation
CN102188522B (en) * 2011-04-29 2013-04-17 陕西白鹿制药股份有限公司 Traditional Chinese medicine composition for treating constipation
CN102416111A (en) * 2011-11-26 2012-04-18 王少云 Chinese medicinal composition for treating cattle cotton cake positioning and preparation method thereof
CN103251046A (en) * 2012-04-23 2013-08-21 乔德京 Health food for enhancing immunity
CN103405635A (en) * 2013-08-30 2013-11-27 石欣 Traditional Chinese medicine composition for treating middle and old aged constipation
CN104146241B (en) * 2013-12-19 2015-12-02 河南茗轩食品科技有限公司 A kind of help defaecation health composition and preparation method
CN104146241A (en) * 2013-12-19 2014-11-19 河南茗轩食品科技有限公司 Health composition capable of benefiting bodies and relaxing bowels and preparation method of health composition
CN103877540A (en) * 2014-03-06 2014-06-25 魏伟 Traditional Chinese medicine for treating caesarean section postoperation false intestinal obstruction and preparation method thereof
CN104587016B (en) * 2015-01-13 2017-06-16 河南省洛阳正骨医院河南省骨科医院 A kind of Chinese traditional medicine navel patch and preparation method for treating constipation
CN105232854A (en) * 2015-11-26 2016-01-13 河南中医学院 Traditional Chinese medicine pill treating empirical constipation
CN105343512A (en) * 2015-12-16 2016-02-24 齐鲁工业大学 Traditional Chinese medicine composition for treating constipation and preparation method thereof
CN108079152A (en) * 2018-01-16 2018-05-29 暨南大学 A kind of Chinese prescription for being used for digestive system function obstacle and inflammation
CN112076170A (en) * 2020-08-20 2020-12-15 浙江康乐药业股份有限公司 Tablet with function of relaxing bowels

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