CN101019985A - Constipation treating Chinese medicine - Google Patents
Constipation treating Chinese medicine Download PDFInfo
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- CN101019985A CN101019985A CN 200710064845 CN200710064845A CN101019985A CN 101019985 A CN101019985 A CN 101019985A CN 200710064845 CN200710064845 CN 200710064845 CN 200710064845 A CN200710064845 A CN 200710064845A CN 101019985 A CN101019985 A CN 101019985A
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Abstract
The present invention relates to one kind of Chinese medicine preparation for treating constipation. The Chinese medicine preparation is prepared with rhubarb, senna leaf, aloe, cassia seed and other Chinese medicinal materials. It has the functions of relieving constipation and promoting digestion to dispel food stagnation. The present invention is developed through combining Chinese medicine theory and modern research result. The Chinese medicine preparation has determined curative effect, high safety, no toxic side effect and low cost.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of constipation, is that a kind of Chinese patent medicine for the treatment of constipation is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to technical field of Chinese patent medicine.
Background technology
Constipation system is because of deficiency of both vital energy and Yin, or dryness-heat stagnating in the interior, and due to internal organs gas was not smooth, with the infrequent defecation time lengthening, constipation with dry stool was difficult to resolve the disease into main clinical manifestation.Often refer to habitual constipation.Primary disease can betide any age patient, and young and middle-aged sickness rate is about 1%～5%, and old people's sickness rate both had been found in the process of multiple disease up to 15%～30%, can independently occur again, also is physical work minimizing or long-term bed patient's common complication.
Constipation traditional Chinese medical science title at all times is a lot, " difficulty in defecation ", " back is unfavorable ", " spleen-constipation ", " constipation caused by accumulation of heat ", " constipation of YIN type ", " intestinal knot ", " constipation due to pathogenic wind ", " functional constipation ", " wind-dryness ", " heat is dry ", " constipation due to insufficiency " etc. is arranged, existing general designation " constipation ".
Chinese medicine think constipation be a variety of causes cause the large intestine conduction function not normal due to, its reason has: 1, large intestine dryness-heat stagnating in the interior.2, depression and stagnation of QI.3, qi-blood-body fluid is lost empty.4, year is high weak.The sick position of primary disease is at large intestine, and is relevant with lung, liver,spleen,kidney.So the traditional Chinese medical science is divided into the deficiency and excess two ends in dialectical treatment, with sthenia syndrome requiring purgation, deficiency syndrome should be treated by tonifying method is the rule of treatment; Constipation of excess type is divided into: functional constipation, constipation due to disorder of QI.Constipation due to insufficiency is divided into: the deficiency of vital energy is secret, hematasthenic constipation, suffer from a deficiency of the kidney secret, the deficiency of YIN is secret.Chronic constipation is a kind of commonly encountered diseases of digestive system.Since constipation repeatedly or continue outbreak, bring very big misery to the patient, influence people's live and work, even can bring out or increase the weight of old people's cardiovascular and cerebrovascular disease and cause intestinal obstruction, threat to life safety.Though in recent years the pathogenesis of primary disease is studied, think with defecation adynamia, spastic colon, the rectum defecation reflex is blunt or forfeiture, autonomous defecation reflex weaken, encysted rectum etc. is relevant, but western medicine, takes stopgap measures and does not effect a permanent cure mainly based on the clothes cathartic the treatment primary disease.Even up-to-date short digestive tract power reinforcing medicine cisapride, the curative effect of its treatment constipation is also not fully up to expectations.
The Chinese medicine constipation not only has superiority aspect relieving constipation, and in constipation relieving, disorderly gastrointestinal function obtains adjusting, and patient's physical condition is improved.Because tcm clinical efficacy is good, has no side effect, and is accepted by the patient easily.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 2.5～10 portions of Aloes of 2.5～10 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
1.5～6 parts of 1.5～6 parts of Radix Angelicae Sinensis of 1.5～6 parts of Semen Prunis of Semen Cassiae
1～4 part of Semen Raphani (parched)
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 3～7 portions of Aloes of 3～7 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
2.5～3.5 parts of 2.5～3.5 parts of Radix Angelicae Sinensis of 2.5～3.5 parts of Semen Prunis of Semen Cassiae
1.5～2.5 parts of Semen Raphani (parched)
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 5 portions of Aloes of 5 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
3 parts of 3 parts of Radix Angelicae Sinensis of 3 parts of Semen Prunis of Semen Cassiae
2 parts of Semen Raphani (parched)
Drug action mechanism among the present invention is as follows:
Radix et Rhizoma Rhei (processed) property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 2495th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Folium Sennae property of medicine is sweet, bitter, cold.Return large intestine channel.Has the treatment of purging heat constipation, the effect of consumer product dredge stasis.Can treat constipation with heat retention, habitual constipation, stagnant abdominal distention, edema tympanites, stomach, duodenal ulcer and hemorrhage etc.(the 3369th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Aloe property of medicine hardship, cold.Return liver, large intestine channel.Have and rush down down liver heat removing, parasiticidal effect.Can treat constipation with heat retention, liver-fire headache, conjunctival congestion infantile convulsion, abdominal pain due to worm stagnation, scabies, hemorrhoid complicated by anal fistula etc.(the 3369th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cassiae property of medicine hardship, sweet, salty is slightly cold.Return liver, kidney, large intestine channel.Has liver heat removing and eyesight improving, the effect of diuretic treatment constipation.Can treat conjunctival congestion and swelling pain, photophobia tear is many, optic atrohic blindness, nyctalopia, headache and dizzy, poor vision, tympanites, habitual constipation, toxic swelling, tinea disease etc.(the 1310th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Pruni property of medicine suffering, hardship, sweet, flat.Return spleen, large intestine, small intestine meridian.Has intestine moistening treatment constipation, the effect of therapeutic method to keep the adverse QI flowing downwards diuretic.Can treat the dryness of the intestine constipation, dysuria, edema abdominal distention, beriberi etc.(the 1858th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Raphani (parched) property of medicine suffering, sweet, flat.Return spleen, stomach, lung, large intestine channel.Has dyspepsia and intestinal stasis relieving, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy behind the dysentery, cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest etc.(the 2495th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch with Radix et Rhizoma Rhei (processed), Folium Sennae and Aloe; With Radix Angelicae Sinensis, Semen Cassiae and Semen Pruni is minister; With Semen Raphani (parched) is that assistant makes.All medicines are harmonious, altogether the effect of tool consumer product dredge stasis, loosening bowel to relieve constipation.The treatment constipation has determined curative effect, and toxic and side effects is little, taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.
Preparation of the present invention, preferably peroral dosage form is as tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention treats constipation and has determined curative effect, has no side effect taking convenience, cheap characteristics.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment constipation.
Constipation efficacy assessment standard: 1, cure: just matter was changeed profit with interior defecation 1 time in 2 days, and unobstructed when separating, short-term does not have recurrence.2, take a turn for the better: just matter was changeed profit with interior defecation in 3 days, and it is smooth that defecation is owed.3, do not heal: symptom does not have improvement.(the 109th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment constipation; Treatment constipation patient 36 examples.Take embodiment 1 capsule, each 2～4, three to four times on the one, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 33 examples and account for 91.6%, 3 examples that take a turn for the better account for 8.4%, and total effective rate reaches 100%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
3 parts of 5 portions of Aloes of 5 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
3 parts of 3 parts of Radix Angelicae Sinensis of 3 parts of Semen Prunis of Semen Cassiae
2 parts of Semen Raphani (parched)
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, and 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～4, three to four times on the one, one month is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
3 parts of 5 portions of Aloes of 5 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
3 parts of 3 parts of Radix Angelicae Sinensis of 3 parts of Semen Prunis of Semen Cassiae
2 parts of Semen Raphani (parched)
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～4, three to four times on the one, one month is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
3 parts of 5 portions of Aloes of 5 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
3 parts of 3 parts of Radix Angelicae Sinensis of 3 parts of Semen Prunis of Semen Cassiae
2 parts of Semen Raphani (parched)
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, and 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, one month is a course of treatment.
Claims (6)
1, a kind of Chinese patent medicine for the treatment of constipation is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 2.5～10 portions of Aloes of 2.5～10 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
1.5～6 parts of 1.5～6 parts of Radix Angelicae Sinensis of 1.5～6 parts of Semen Prunis of Semen Cassiae
1～4 part of Semen Raphani (parched).
2, a kind of Chinese patent medicine for the treatment of constipation according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 3～7 portions of Aloes of 3～7 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
2.5～3.5 parts of 2.5～3.5 parts of Radix Angelicae Sinensis of 2.5～3.5 parts of Semen Prunis of Semen Cassiae
1.5～2.5 parts of Semen Raphani (parched).
3, a kind of Chinese patent medicine for the treatment of constipation according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 5 portions of Aloes of 5 portions of Folium Sennae of Radix et Rhizoma Rhei (processed)
3 parts of 3 parts of Radix Angelicae Sinensis of 3 parts of Semen Prunis of Semen Cassiae
2 parts of Semen Raphani (parched).
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710064845A CN101019985B (en) | 2007-03-28 | 2007-03-28 | Constipation treating Chinese medicine |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200710064845A CN101019985B (en) | 2007-03-28 | 2007-03-28 | Constipation treating Chinese medicine |
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| CN101019985A true CN101019985A (en) | 2007-08-22 |
| CN101019985B CN101019985B (en) | 2010-05-19 |
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| CN200710064845A Expired - Fee Related CN101019985B (en) | 2007-03-28 | 2007-03-28 | Constipation treating Chinese medicine |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102861233A (en) * | 2012-08-31 | 2013-01-09 | 王霞 | Drug for treating constipation |
| CN101720931B (en) * | 2008-10-22 | 2013-05-01 | 杨光孝 | Notoginseng clearing tea |
| CN103285215A (en) * | 2012-02-27 | 2013-09-11 | 武秋石 | Medicinal composition for treating constipation |
| CN104042725A (en) * | 2014-05-13 | 2014-09-17 | 魏本雪 | Traditional Chinese medicine patch for treating infantile constipation |
| CN105125746A (en) * | 2015-08-24 | 2015-12-09 | 张建军 | Chinese patent medicine for treating constipation, and preparation method of decoction thereof |
| CN105194264A (en) * | 2015-10-29 | 2015-12-30 | 青岛海之源智能技术有限公司 | Traditional Chinese medicinal electuary for treating constipation, and preparation method thereof |
| CN105878559A (en) * | 2016-04-18 | 2016-08-24 | 南昌济顺制药有限公司 | Medicine composition or health-care food with bowel relaxing and constipation relieving efficacy |
| CN105920231A (en) * | 2016-06-28 | 2016-09-07 | 陆永 | Traditional Chinese medicine preparation and capsule for treating constipation and preparation method of traditional Chinese medicine preparation and capsule |
| CN107440118A (en) * | 2017-08-16 | 2017-12-08 | 河南树铭药业有限公司 | A kind of health food with defecating feces excretion and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058175C (en) * | 1997-01-30 | 2000-11-08 | 张汉英 | Chinese medicine for treating constipation |
| CN100556424C (en) * | 2003-09-30 | 2009-11-04 | 杨中文 | A kind of Chinese patent medicine for the treatment of hemorrhoid and constipation |
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2007
- 2007-03-28 CN CN200710064845A patent/CN101019985B/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101720931B (en) * | 2008-10-22 | 2013-05-01 | 杨光孝 | Notoginseng clearing tea |
| CN103285215A (en) * | 2012-02-27 | 2013-09-11 | 武秋石 | Medicinal composition for treating constipation |
| CN103285215B (en) * | 2012-02-27 | 2014-10-08 | 武秋石 | Medicinal composition for treating constipation |
| CN102861233A (en) * | 2012-08-31 | 2013-01-09 | 王霞 | Drug for treating constipation |
| CN102861233B (en) * | 2012-08-31 | 2014-03-19 | 王霞 | Drug for treating constipation |
| CN104042725A (en) * | 2014-05-13 | 2014-09-17 | 魏本雪 | Traditional Chinese medicine patch for treating infantile constipation |
| CN104042725B (en) * | 2014-05-13 | 2016-06-22 | 魏本雪 | The Chinese herbs paste for the treatment of infantile constipation |
| CN105125746A (en) * | 2015-08-24 | 2015-12-09 | 张建军 | Chinese patent medicine for treating constipation, and preparation method of decoction thereof |
| CN105194264A (en) * | 2015-10-29 | 2015-12-30 | 青岛海之源智能技术有限公司 | Traditional Chinese medicinal electuary for treating constipation, and preparation method thereof |
| CN105878559A (en) * | 2016-04-18 | 2016-08-24 | 南昌济顺制药有限公司 | Medicine composition or health-care food with bowel relaxing and constipation relieving efficacy |
| CN105920231A (en) * | 2016-06-28 | 2016-09-07 | 陆永 | Traditional Chinese medicine preparation and capsule for treating constipation and preparation method of traditional Chinese medicine preparation and capsule |
| CN107440118A (en) * | 2017-08-16 | 2017-12-08 | 河南树铭药业有限公司 | A kind of health food with defecating feces excretion and preparation method thereof |
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| CN101019985B (en) | 2010-05-19 |
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