CN100496547C - Chinese-medicinal preparation for treating cough - Google Patents
Chinese-medicinal preparation for treating cough Download PDFInfo
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- CN100496547C CN100496547C CNB2006101505598A CN200610150559A CN100496547C CN 100496547 C CN100496547 C CN 100496547C CN B2006101505598 A CNB2006101505598 A CN B2006101505598A CN 200610150559 A CN200610150559 A CN 200610150559A CN 100496547 C CN100496547 C CN 100496547C
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Abstract
A Chinese medicine for treating cold, cough and asthma is prepared from 9 Chinese- medicinal materials including honeysuckle flower, scutellaria, mulberry leaf, chrysanthemum flower, etc.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of flu, is that a kind of flu for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Flu is that the common exogenous diseases that emits due to the ailment said due to cold or exposure is touched in impression.Clinical manifestation is its feature with nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating, general malaise etc.Cause of disease diseases caused by exogenous pathogenic factor six climate exopathogens, the time row virus, function weakens outside human body is defended, and can not regulate in the strain, from fur, mouth and nose invasion, the evil lung of violating is defended, and defends the table discord and causes a disease.In general, flu seldom has the situation that the change of disease takes place, the short and being easy to recover of the course of disease, but the time sense heavy card, old man, baby children, weak patients, also variable sometimes sick he.Because of primary disease has certain infectiousness, very high at susceptible sickness rate in season, people ' s health and work production are often brought bigger influence, therefore actively control.And at present, one-sidedness is arranged, and side effect is big in the treatment of doctor trained in Western medicine.There is anaphylactoid patient may cause shock to cause death.Utilization Chinese herbal treatment flu is the work of always studying, but present curative effect of medication can not be satisfactory.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of flu, and have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
1.0～4.0 parts of 1.5～6.0 parts of SHENGHUANG a kind of reed mentioned in ancient books of 1.5～6.0 parts of Fructus Forsythiaes of Flos Lonicerae
1.0～4.0 parts of 1.0～4.0 parts of Flos Chrysanthemis of 0.1～2.0 part of Folium Mori of Fructus Arctii (parched)
0.1～2.0 part of 0.1～2.0 part of Semen Raphani (parched) of 0.1～2.0 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of SHENGHUANG a kind of reed mentioned in ancient books of 2.5～3.5 parts of Fructus Forsythiaes of Flos Lonicerae
1.5～2.5 parts of 1.5～2.5 parts of Flos Chrysanthemis of 0.5～1.5 part of Folium Mori of Fructus Arctii (parched)
0.5～1.5 part of 0.5～1.5 part of Semen Raphani (parched) of 0.5～1.5 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of SHENGHUANG a kind of reed mentioned in ancient books of 3 parts of Fructus Forsythiaes of Flos Lonicerae
2 parts of 2 parts of Flos Chrysanthemis of 1 part of Folium Mori of Fructus Arctii (parched)
1 part of 1 part of Semen Raphani (parched) of 1 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
Drug action mechanism among the present invention is as follows:
The Flos Lonicerae nature and flavor are sweet, cold.Return lung, the heart, stomach warp.Has heat-clearing and toxic substances removing, the effect of wind-heat dissipating.Can treat the carbuncle furuncle, scrofula anal fistula, sore throat, erysipelas, toxic-heat and blood stasis, flu, epidemic febrile disease heating etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 830th page).
Fructus Forsythiae nature and flavor hardship, be slightly cold.Return lung, the heart, small intestine meridian.Have heat-clearing and toxic substances removing, the knot that disappears looses swollen, and the diuretic effect clears away heart-fire.Can treat carbuncle, scrofula, acute mastitis, erysipelas, flu, epidemic febrile disease from the beginning of, warmly join the army, hyperpyrexia excessive thirst, coma send out speckle, pyretic stranguria urine retention etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 669th page).
SHENGHUANG a kind of reed mentioned in ancient books nature and flavor hardship, cold.Go into the heart, lung, gallbladder, intestine and small intestine warp.Have the removing the relative excess fire, except that damp and hot, hemostasis, antiabortive effect.High fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria be can treat, nosebleed, metrorrhagia, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle etc. told.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1069th page).
Fructus Arctii (parched) nature and flavor suffering, hardship, cold.Attach to the lung and stomach meridians.Has dispelling wind and heat pathogens, lung qi dispersing rash, the effect of subduing swelling and detoxicating.Can treat the cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule is not saturating, and wind is examined and is had an itch, carbuncle sore tumefacting virus etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 305th page).
The Folium Mori nature and flavor are sweet, bitter, cold.Return lung, Liver Channel.Effect with dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.It is dim-sighted etc. to treat flu, lung-heat type cough, dizziness headache, conjunctival congestion.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1055th page).
Flos Chrysanthemi nature and flavor sweetness and bitterness, cold.Return lung, Liver Channel.Have dispelling wind, heat clearing away makes eye bright, the antidotal effect.Can treat headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling etc.(" Chinese medicine voluminous dictionary " the 2009th page).
Stir-baked SEMEN ARMENIACAE AMARUM nature and flavor hardship, tepor; Slightly poisonous; Return lung, large intestine channel.Has the sending down the abnormal ascending QI relieving cough and asthma, the effect of loosening bowel to relieve constipation.Can treat cough and asthma, the fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, dryness of the intestine constipation etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 666th page).
Radix Platycodonis nature and flavor hardship, suffering, flat, tepor.Return lung meridian.Have lung qi dispersing, sore-throat relieving eliminates the phlegm, the effect of evacuation of pus.Can treat the exogenous cough, abundant expectoration, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, hoarseness, skin infection difficulty in discharging of pus etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 982nd page).
Semen Raphani (parched) acrid-sweet flavor, flat, cool.Return spleen, stomach, lung meridian.Have removing food stagnancy stagnate, reduce phlegm heat, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, antidotal effect.Can treat food stagnation distension, phlegmatic cough aphonia, haematemesis, epistaxis, quench one's thirst, dysentery and migraine and general headache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 993rd page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Flos Lonicerae, Fructus Forsythiae, SHENGHUANG a kind of reed mentioned in ancient books and Fructus Arctii (parched), is ministerial drug with Folium Mori, Flos Chrysanthemi and stir-baked SEMEN ARMENIACAE AMARUM, is adjuvant with Radix Platycodonis and Semen Raphani (parched).All medicine phases and the effect that is total to tool heat-clearing and toxic substances removing, dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, relieving cough and asthma, the treatment flu has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, preferred Chinese medicine preparation is a peroral dosage form, as: tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the preventing cold of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat flu, and the prevention of catching a cold is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment flu.
Flu curative effect determinate standard (" new Chinese medicine clinical research guideline " Zheng Xiao cornel chief editor Chinese Medicine section
The 60th page of skill publishing house in May, 2002 front page).
1, clinic control tcm clinical practice symptom, sign disappear or basic the disappearance; The sign integration reduces 〉=95%.
2, produce effects tcm clinical practice symptom, sign are obviously improved, and the sign integration reduces 〉=70%.
3, effectively tcm clinical practice symptom, sign all take a favorable turn, and the sign integration reduces 〉=30%.
4, invalid tcm clinical practice symptom, sign all do not have obvious improvement, even increase the weight of, the sign integration reduces less than 30%.
As follows through clinical test results; Treatment flu patient 58 examples are taken embodiment 1 capsule, each 2-10 grain, and every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.Three days is a course of treatment, take continuously two the course of treatment observe the curative effect.The recovery from illness example accounts for 73.9%, and produce effects 7 examples account for 12.9%, and effective 3 examples account for 5.1%, and invalid 2 examples account for 3.5%, and total effective rate reaches 96.5%.After two course of therapy, symptoms such as patient's nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating etc. all have clear improvement or fully recover.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
2 parts of 3 parts of SHENGHUANG a kind of reed mentioned in ancient books of 3 parts of Fructus Forsythiaes of Flos Lonicerae
2 parts of 2 parts of Flos Chrysanthemis of 1 part of Folium Mori of Fructus Arctii (parched)
1 part of 1 part of Semen Raphani (parched) of 1 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
Preparation method is that raw materials such as extracting honeysuckle, Fructus Forsythiae, SHENGHUANG a kind of reed mentioned in ancient books, Fructus Arctii (parched), Folium Mori, Flos Chrysanthemi, stir-baked SEMEN ARMENIACAE AMARUM, Radix Platycodonis and Semen Raphani (parched) decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three days is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
2 parts of 3 parts of SHENGHUANG a kind of reed mentioned in ancient books of 3 parts of Fructus Forsythiaes of Flos Lonicerae
2 parts of 2 parts of Flos Chrysanthemis of 1 part of Folium Mori of Fructus Arctii (parched)
1 part of 1 part of Semen Raphani (parched) of 1 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
Preparation method is an extracting honeysuckle, Fructus Forsythiae, SHENGHUANG a kind of reed mentioned in ancient books, Fructus Arctii (parched), Folium Mori, Flos Chrysanthemi, stir-baked SEMEN ARMENIACAE AMARUM, raw material such as Radix Platycodonis and Semen Raphani (parched) decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three days is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
2 parts of 3 parts of SHENGHUANG a kind of reed mentioned in ancient books of 3 parts of Fructus Forsythiaes of Flos Lonicerae
2 parts of 2 parts of Flos Chrysanthemis of 1 part of Folium Mori of Fructus Arctii (parched)
1 part of 1 part of Semen Raphani (parched) of 1 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM
Preparation method is an extracting honeysuckle, Fructus Forsythiae, SHENGHUANG a kind of reed mentioned in ancient books, Fructus Arctii (parched), Folium Mori, Flos Chrysanthemi, stir-baked SEMEN ARMENIACAE AMARUM, raw material such as Radix Platycodonis and Semen Raphani (parched) decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, and the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, three days is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of flu is characterized in that it is made by following raw materials by weight proportions:
1.0～4.0 parts of 1.5～6.0 parts of SHENGHUANG a kind of reed mentioned in ancient books of 1.5～6.0 parts of Fructus Forsythiaes of Flos Lonicerae
1.0～4.0 parts of 1.0～4.0 parts of Flos Chrysanthemis of 0.1～2.0 part of Folium Mori of Fructus Arctii (parched)
0.1～2.0 part of 0.1～2.0 part of Semen Raphani (parched) of 0.1～2.0 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM.
2, a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each crude drug is:
1.5～2.5 parts of 2.5～3.5 parts of SHENGHUANG a kind of reed mentioned in ancient books of 2.5～3.5 parts of Fructus Forsythiaes of Flos Lonicerae
1.5～2.5 parts of 1.5～2.5 parts of Flos Chrysanthemis of 0.5～1.5 part of Folium Mori of Fructus Arctii (parched)
0.5～1.5 part of 0.5～1.5 part of Semen Raphani (parched) of 0.5～1.5 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM.
3, a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each crude drug is:
2 parts of 3 parts of SHENGHUANG a kind of reed mentioned in ancient books of 3 parts of Fructus Forsythiaes of Flos Lonicerae
2 parts of 2 parts of Flos Chrysanthemis of 1 part of Folium Mori of Fructus Arctii (parched)
1 part of 1 part of Semen Raphani (parched) of 1 part of Radix Platycodonis of stir-baked SEMEN ARMENIACAE AMARUM.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101505598A CN100496547C (en) | 2006-10-19 | 2006-10-19 | Chinese-medicinal preparation for treating cough |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101505598A CN100496547C (en) | 2006-10-19 | 2006-10-19 | Chinese-medicinal preparation for treating cough |
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| Publication Number | Publication Date |
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| CN1939450A CN1939450A (en) | 2007-04-04 |
| CN100496547C true CN100496547C (en) | 2009-06-10 |
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| CNB2006101505598A Expired - Fee Related CN100496547C (en) | 2006-10-19 | 2006-10-19 | Chinese-medicinal preparation for treating cough |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101254255B (en) * | 2008-04-11 | 2011-06-01 | 刘宗升 | Traditional Chinese medicine preparation for curing cold |
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| CN1939450A (en) | 2007-04-04 |
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Granted publication date: 20090610 Termination date: 20111019 |