CN1931262B - Common cold treating Chinese medicine preparation - Google Patents
Common cold treating Chinese medicine preparation Download PDFInfo
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- CN1931262B CN1931262B CN200610140570A CN200610140570A CN1931262B CN 1931262 B CN1931262 B CN 1931262B CN 200610140570 A CN200610140570 A CN 200610140570A CN 200610140570 A CN200610140570 A CN 200610140570A CN 1931262 B CN1931262 B CN 1931262B
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Abstract
The present invention relates to one kind of common cold treating Chinese medicine preparation. The Chinese medicine preparation is prepared with nine kinds of Chinese medicinal materials, including schizonepta herb, ledebouriella root, perilla leaf, notoperygium root, bupleurum root, etc. It has the functions of relieving superficial affection, dispersing cold, promoting lung-qi flow and relieving cough. It is used to treat common cold and has the advantages of fast acting, high curative effect and no toxic side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of flu, is that a kind of flu for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Flu is that the common exogenous diseases that emits due to the ailment said due to cold or exposure is touched in impression.Clinical manifestation is its feature with nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating, general malaise etc.Cause of disease diseases caused by exogenous pathogenic factor six climate exopathogens, the time row virus, function weakens outside human body is defended, and can not regulate in the strain, from fur, mouth and nose invasion, the evil lung of violating is defended, and defends the table discord and causes a disease.The pilosity in general winter of catching a cold.Its cardinal symptom is obviously to be afraid of cold, even put on many clothes, the people also can feel a sense of cold.Patient's nasal mucus is rarer, and expectorant is thinner, and heating is lossless.In general, flu seldom has the situation that the change of disease takes place, the short and being easy to recover of the course of disease, but the time sense heavy card, old man, baby children, weak patients, also variable sometimes sick he.Because of primary disease has certain infectiousness, very high at susceptible sickness rate in season, people ' s health and work production are often brought bigger influence, therefore actively control.And at present, one-sidedness is arranged, and side effect is big in the treatment of doctor trained in Western medicine.There is anaphylactoid patient may cause shock to cause death.Utilization Chinese herbal treatment flu is the work of always studying, but present curative effect of medication can not be satisfactory.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of flu, and have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by following raw materials by weight proportions:
1.5～6.0 parts of 0.1～2.0 part of Folium Perillaes of 1.5～6.0 parts of Radix Saposhnikoviaes of Herba Schizonepetae
1.0～4.0 parts of 1.0～4.0 parts of Radix Peucedanis of 0.1～2.0 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
0.1～2.0 part of 0.1～2.0 part of Semen Raphani (parched) of 1.0～4.0 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
The weight proportion of each crude drug of optimization formula of the present invention is:
2.5～3.5 parts of 0.5～1.5 part of Folium Perillaes of 2.5～3.5 parts of Radix Saposhnikoviaes of Herba Schizonepetae
1.5～2.5 parts of 1.5～2.5 parts of Radix Peucedanis of 0.5～1.5 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
0.5～1.5 part of 0.5～1.5 part of Semen Raphani (parched) of 1.5～2.5 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
The weight proportion of each crude drug of optimum formula of the present invention is:
3 parts of 1 part of Folium Perillaes of 3 parts of Radix Saposhnikoviaes of Herba Schizonepetae
2 parts of 2 parts of Radix Peucedanis of 1 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
1 part of 1 part of Semen Raphani (parched) of 2 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
Drug action mechanism among the present invention is as follows:
Herba Schizonepetae nature and flavor suffering, temperature.Return lung, Liver Channel.Have the diffusing wind that induces sweat, rash is antipruritic, treating blood disorders hemostasis, the clear sharp head, analgesic effect.Can treat flu, headache, measles, rubella, skin infection from the beginning of etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 876th page).
Radix Saposhnikoviae property acrid-sweet flavor, temperature. return bladder, lung, spleen channel. have and deliver, dispel the wind, win and wet, the analgesic effect. can treat affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, and the extremity contraction is anxious, tetanus etc. (" Chinese medicine voluminous dictionary " the 986th page).
Folium Perillae nature and flavor suffering, temperature.Return lung, spleen channel.Have and deliver, cold expelling is regulated the flow of vital energy, and battalion.Can treat cold, fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen, frequent fetal movement etc.(" Chinese medicine voluminous dictionary " the 2357th page).
The Rhizoma Et Radix Notopterygii nature and flavor are arduous, temperature.Return bladder, kidney channel.Has diffusing exterior cold, wind-damp dispelling, the effect in sharp joint.Can treat cold, it is lossless to have a headache, anemofrigid-damp arthralgia, and the stiffness of the nape muscular contracture, joint is ached, edema due to wind pathogen edema, skin sore etc.(" Chinese medicine voluminous dictionary " the 986th page).
Give birth to Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Have reconciling superficies and interior, soothing the liver, the effect of yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Radix Peucedani nature and flavor hardship, suffering, cold, be slightly cold.Return lung, spleen channel.Has diffusing wind heat clearing away, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat that headache due to pathogenic wind-heat, expectorant dyspnea of heat type are coughed, vomiting, chest and diaphragm full vexed, cough up phlegm yellow thick etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 951st page).
Stir-baked SEMEN ARMENIACAE AMARUM nature and flavor hardship, tepor; Slightly poisonous; Return lung, large intestine channel.Has the sending down the abnormal ascending QI relieving cough and asthma, the effect of loosening bowel to relieve constipation.Can treat cough and asthma, the fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, dryness of the intestine constipation etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 666th page).
Radix Platycodonis nature and flavor hardship, suffering, flat, tepor.Return lung meridian.Have lung qi dispersing, sore-throat relieving eliminates the phlegm, the effect of evacuation of pus.Can treat the exogenous cough, abundant expectoration, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, hoarseness, skin infection difficulty in discharging of pus etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 982nd page).
Semen Raphani (parched) acrid-sweet flavor, flat, cool.Return spleen, stomach, lung meridian.Have removing food stagnancy stagnate, reduce phlegm heat, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, antidotal effect.Can treat food stagnation distension, phlegmatic cough aphonia, haematemesis, epistaxis, quench one's thirst, dysentery and migraine and general headache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 993rd page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Herba Schizonepetae and Folium Perillae, is ministerial drug with Radix Peucedani, stir-baked SEMEN ARMENIACAE AMARUM, Rhizoma Et Radix Notopterygii and Radix Saposhnikoviae, is adjuvant drug with giving birth to Radix Bupleuri and Semen Raphani (parched), is messenger drug with Radix Platycodonis.All medicines is the induce sweat effect of cold expelling, lung qi dispersing cough-relieving of tool mutually and altogether, and the treatment anemofrigid cold has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, preferred Chinese medicine preparation is a peroral dosage form, as: tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilize the comprehensive function treatment and the preventing cold of the Chinese medicine of respectively distinguishing the flavor of, nontoxic to human body. show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat flu, and the prevention of catching a cold is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment anemofrigid cold.Anemofrigid cold curative effect determinate standard (the 60th page of " new Chinese medicine clinical research guideline " Zheng Xiao cornel chief editor Chinese Medicine science and technology publishing house in May, 2002 front page).
1, clinical recovery tcm clinical practice symptom, sign disappear or basic the disappearance; The sign integration reduces 〉=95%.
2, produce effects tcm clinical practice symptom, sign are obviously improved, and the sign integration reduces 〉=70%.
3, effectively tcm clinical practice symptom, sign all take a favorable turn, and the sign integration reduces 〉=30%.
4, invalid tcm clinical practice symptom, sign all do not have obvious improvement, even increase the weight of, the sign integration reduces less than 30%.
As follows through clinical test results; Treatment anemofrigid cold patient 42 examples, male's 23 examples, women's 19 examples, the age is 15～75 years old.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.Two days is a course of treatment, take continuously three the course of treatment observe the curative effect.35 examples of fully recovering account for 83.3%, and produce effects 2 examples account for 4.76%, and 3 examples that take a turn for the better account for 7.14%, and invalid 2 examples account for 4.76%, and total effective rate reaches 95.24%.After two course of therapy, symptoms such as patient's nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating etc. all have clear improvement or fully recover.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule is pressed following weight weighting raw materials:
3 parts of 1 part of Folium Perillaes of 3 parts of Radix Saposhnikoviaes of Herba Schizonepetae
2 parts of 2 parts of Radix Peucedanis of 1 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
1 part of 1 part of Semen Raphani (parched) of 2 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, and 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three days is a course of treatment.
Embodiment 2 tablets are pressed following weight weighting raw materials:
3 parts of 1 part of Folium Perillaes of 3 parts of Radix Saposhnikoviaes of Herba Schizonepetae
2 parts of 2 parts of Radix Peucedanis of 1 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
1 part of 1 part of Semen Raphani (parched) of 2 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, and 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly. and half an hour ante cibum is oral usually, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three days is a course of treatment.
Embodiment 3 granules are pressed following weight weighting raw materials:
3 parts of 1 part of Folium Perillaes of 3 parts of Radix Saposhnikoviaes of Herba Schizonepetae
2 parts of 2 parts of Radix Peucedanis of 1 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
1 part of 1 part of Semen Raphani (parched) of 2 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5～2 hours for the first time, and 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, three days is a course of treatment.
Claims (3)
1. Chinese medicine preparation for the treatment of flu is characterized in that it is made by following raw materials by weight proportions:
1.5～6.0 parts of 0.1～2.0 part of Folium Perillaes of 1.5～6.0 parts of Radix Saposhnikoviaes of Herba Schizonepetae
1.0～4.0 parts of 1.0～4.0 parts of Radix Peucedanis of 0.1～2.0 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
0.1～2.0 part of 0.1～2.0 part of Semen Raphani (parched) of 1.0～4.0 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
2. a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each crude drug is:
2.5～3.5 parts of 0.5～1.5 part of Folium Perillaes of 2.5～3.5 parts of Radix Saposhnikoviaes of Herba Schizonepetae
1.5～2.5 parts of 1.5～2.5 parts of Radix Peucedanis of 0.5～1.5 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
0.5～1.5 part of 0.5～1.5 part of Semen Raphani (parched) of 1.5～2.5 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
3. a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 1 part of Folium Perillaes of 3 parts of Radix Saposhnikoviaes of Herba Schizonepetae
2 parts of 2 parts of Radix Peucedanis of 1 part of living Radix Bupleuri of Rhizoma Et Radix Notopterygii
1 part of 1 part of Semen Raphani (parched) of 2 parts of Radix Platycodoniss of stir-baked SEMEN ARMENIACAE AMARUM.
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| CN200610140570A CN1931262B (en) | 2006-10-17 | 2006-10-17 | Common cold treating Chinese medicine preparation |
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| CN104800287A (en) * | 2015-05-11 | 2015-07-29 | 李汶峰 | Traditional Chinese medicine for treating common cold in deficiency body |
| CN111297996A (en) * | 2020-04-09 | 2020-06-19 | 国华鹏源股份有限公司 | Novel tablet for treating common cold due to wind-cold |
| CN111419897A (en) * | 2020-05-22 | 2020-07-17 | 平顶山学院 | A kind of medicated bath medicine for preventing and treating children's wind-cold cold and preparation method |
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| CN1593640A (en) * | 2004-06-24 | 2005-03-16 | 朱智文 | Pills for treating wind cold type cold and its prescription |
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| CN1593640A (en) * | 2004-06-24 | 2005-03-16 | 朱智文 | Pills for treating wind cold type cold and its prescription |
Non-Patent Citations (4)
| Title |
|---|
| .败毒散加减治疗小儿感冒62例临床观察.现代中医药 4.2001,(4),24. |
| 张德全 |
| 王冠彬 |
| 王冠彬;张德全;.败毒散加减治疗小儿感冒62例临床观察.现代中医药 4.2001,(4),24. * |
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