CN101085169A - Traditional Chinese medicine for treating uric acid nephritis - Google Patents

Traditional Chinese medicine for treating uric acid nephritis Download PDF

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Publication number
CN101085169A
CN101085169A CN 200710117896 CN200710117896A CN101085169A CN 101085169 A CN101085169 A CN 101085169A CN 200710117896 CN200710117896 CN 200710117896 CN 200710117896 A CN200710117896 A CN 200710117896A CN 101085169 A CN101085169 A CN 101085169A
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China
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parts
chinese medicine
radix
nephritis
uric acid
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CN 200710117896
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CN 200710117896 priority Critical patent/CN101085169A/en
Publication of CN101085169A publication Critical patent/CN101085169A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating nephritis, which is prepared from more than ten kinds of Chinese medicinal herbs including raw astragalus root, root of red rooted saliva, oldenlandia and hairy vein agrimony.

Description

A kind of Chinese medicine of treatment uric acid nephritis
Technical field
The present invention relates to treat a kind of Chinese medicine of uric acid nephritis, is that a kind of uric acid nephritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Urate nephropathy is meant the renal damage of urate deposition due to renal medulla, a matter or the far-end collecting tubule.Clinical in soreness of waist pain, polyuria, nocturia, or hematuria, urinary stone, or renal colic, oliguria anuria, or anemia, nausea and vomiting etc. are main clinical manifestation.And often with the outer symptom of kidneys such as redness and swelling of joints burning pain such as the sole of the foot, toe, knee joint, wrist, finger and heating.The concealment of primary disease onset is made slow progress, and eventually to chronic renal failure, also can sharply increase the weight of, and acute renal failure takes place.This onset of disease with extremities joint swell and ache, lumbago, hematuria, stranguria be main performance, being developed to the later stage is feature with oliguria, vomiting, edema.Because the raising of national life level and the variation of dietary structure are increased the incidence rate of hyperuricemia, urate nephropathy year by year.Though hyperuricemia patient only has 10%~20% clinical kidney performance is arranged, and it is reported that there is kidney damage in various degree in nearly all patient on pathology, many patients often develop into renal failure just changes the prescription on individual diagnosis of kidney section.Urate nephropathy comes into one's own day by day in recent years, and traditional Chinese medical science research urate nephropathy has obtained very gratifying progress.Tcm clinical practice medicine typing scheme is gradually improved, and the advantage of performance Chinese medicine all obtains curative effect preferably, has not only alleviated the toxic and side effects of Western medicine, and has improved clinical symptoms, reduces blood uric acid, consolidates aspect such as curative effect and has shown bigger advantage, can take for a long time.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of uric acid nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Salviae Miltiorrhizaes of 1.5~6 parts of Rhizoma Smilacis Glabraes of Radix Astragali
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 parts of Herba Agrimoniaes of Radix Rehmanniae
1.0~4 parts of 1.0~4 parts of Folium Pyrrosiaes of 1.0~4 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
0.1~2 part of 0.1~2 part of Radix Sophorae Flavescentis of 0.1~2 portion of Semen Plantaginis of Folium Perillae.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Salviae Miltiorrhizaes of 2.5~3.5 parts of Rhizoma Smilacis Glabraes of Radix Astragali
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 parts of Herba Agrimoniaes of Radix Rehmanniae
1.5~2.5 parts of 1.5~2.5 parts of Folium Pyrrosiaes of 1.5~2.5 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
0.5~1.5 part of 0.5~1.5 part of Radix Sophorae Flavescentis of 0.5~1.5 portion of Semen Plantaginis of Folium Perillae.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Smilacis Glabraes of Radix Astragali
2 parts in 2 parts of Poria of 2 parts of Herba Agrimoniaes of Radix Rehmanniae
2 parts of 2 parts of Folium Pyrrosiaes of 2 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
1 part of 1 part of Radix Sophorae Flavescentis of 1 portion of Semen Plantaginis of Folium Perillae.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Smilacis Glabrae property of medicine is sweet, light, and is flat.Return liver,kidney,spleen, stomach warp.Have removing damp-heat, let out turbid detoxifcation, the effect of easing joint movement.Can treat syphilis, stranguria with turbid discharge is had loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism etc.(the 124th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Herba Agrimoniae property of medicine hardship, puckery, flat.Return lung, liver, spleen channel.Has astringing to arrest bleeding, removing food stagnancy dysentery relieving, the effect of removing toxic substances and promoting subsidence of swelling.Can treat spitting of blood, spit blood, epistaxis, hematuria is had blood in stool, metrorrhagia and traumatic hemorrhage, diarrhoea, dysentery is taken off the power impairment caused by overstrain, malaria, furuncle carbuncle, trichomonal vaginitis etc.(the 938th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Hedyotidis Diffusae property of medicine hardship, sweet, cold.GUIXIN, lung, liver, large intestine channel.Has heat-clearing and toxic substances removing, promoting blood circulation and detumescence, the effect of dampness removing jaundice eliminating.Can treat lung-heat breathes heavily and coughs lung abscess, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery enteritis, jaundice due to damp-heat, cancerous protuberance etc.(the 1041st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Folium Pyrrosiae property of medicine hardship, sweet, cold.Return lung, kidney, urinary bladder channel.Has relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, the effect of cooling blood for hemostasis.Can treat stranguria, edema, dysuria, the expectorant heat syndrome cough is breathed heavily, and spitting of blood is spitted blood epistaxis, metrorrhagia and traumatic hemorrhage etc.(the 811st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Folium Perillae property of medicine suffering, temperature.Return lung, spleen, stomach warp.Have expelling cold and relieving exterior syndrome, promoting the circulation of QI and reducing phlegm, antiabortive, solving toxin of fish and crab.Can treat wind and cold table disease, cough with copious phlegm, fullness in the epigastrium and chest, nausea and vomiting, stomachache is vomited and diarrhoea, nausea discord, pregnancy reactions, ichthyophagy Eriocheir sinensis poisoning etc.(the 3288th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, large intestine channel.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali, Rhizoma Smilacis Glabrae and Radix Salviae Miltiorrhizae; With Radix Rehmanniae, Herba Agrimoniae, Poria, Herba Hedyotidis Diffusae, Rhizoma Alismatis and Folium Pyrrosiae is ministerial drug; With Folium Perillae, Semen Plantaginis and Radix Sophorae Flavescentis is adjuvant.All medicines are harmonious, and are total to the tool benefiting QI for activating blood circulation, the effect of clearing away heat-damp and promoting diuresis.The treatment uric acid nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment uric acid nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat uric acid nephritis, and the prevention of uric acid nephritis is also had good effect, and the treatment uric acid nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment uric acid nephritis; Treatment uric acid nephritis patient 24 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 41.67%, and 11 examples that take a turn for the better account for 45.83%, and invalid 3 examples account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Smilacis Glabraes of Radix Astragali
2 parts in 2 parts of Poria of 2 parts of Herba Agrimoniaes of Radix Rehmanniae
2 parts of 2 parts of Folium Pyrrosiaes of 2 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
1 part of 1 part of Radix Sophorae Flavescentis of 1 portion of Semen Plantaginis of Folium Perillae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment uric acid nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine of treatment uric acid nephritis is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Salviae Miltiorrhizaes of 1.5~6 parts of Rhizoma Smilacis Glabraes of Radix Astragali
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 parts of Herba Agrimoniaes of Radix Rehmanniae
1.0~4 parts of 1.0~4 parts of Folium Pyrrosiaes of 1.0~4 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
0.1~2 part of 0.1~2 part of Radix Sophorae Flavescentis of 0.1~2 portion of Semen Plantaginis of Folium Perillae.
2, a kind of Chinese medicine of treatment uric acid nephritis according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Salviae Miltiorrhizaes of 2.5~3.5 parts of Rhizoma Smilacis Glabraes of Radix Astragali
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 parts of Herba Agrimoniaes of Radix Rehmanniae
1.5~2.5 parts of 1.5~2.5 parts of Folium Pyrrosiaes of 1.5~2.5 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
0.5~1.5 part of 0.5~1.5 part of Radix Sophorae Flavescentis of 0.5~1.5 portion of Semen Plantaginis of Folium Perillae.
3, a kind of Chinese medicine of treatment uric acid nephritis according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Smilacis Glabraes of Radix Astragali
2 parts in 2 parts of Poria of 2 parts of Herba Agrimoniaes of Radix Rehmanniae
2 parts of 2 parts of Folium Pyrrosiaes of 2 portions of Rhizoma Alismatis of Herba Hedyotidis Diffusae
1 part of 1 part of Radix Sophorae Flavescentis of 1 portion of Semen Plantaginis of Folium Perillae.
CN 200710117896 2007-06-26 2007-06-26 Traditional Chinese medicine for treating uric acid nephritis Pending CN101085169A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397314A (en) * 2011-11-07 2012-04-04 刘鹏 Health-care product for preventing and treating renal disease of newborn Tibetan mastiff in low-altitude region
CN104435567A (en) * 2014-11-07 2015-03-25 成都华熹科技有限公司 Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout
CN113616688A (en) * 2021-10-08 2021-11-09 广东海洋大学 Anserine composition for repairing kidney injury and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397314A (en) * 2011-11-07 2012-04-04 刘鹏 Health-care product for preventing and treating renal disease of newborn Tibetan mastiff in low-altitude region
CN102397314B (en) * 2011-11-07 2013-08-21 赵冬迎 Health-care product for preventing and treating renal disease of newborn Tibetan mastiff in low-altitude region
CN104435567A (en) * 2014-11-07 2015-03-25 成都华熹科技有限公司 Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout
CN113616688A (en) * 2021-10-08 2021-11-09 广东海洋大学 Anserine composition for repairing kidney injury and application thereof
CN113616688B (en) * 2021-10-08 2022-03-11 广东海洋大学 Anserine composition for repairing kidney injury and application thereof

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
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Open date: 20071212