CN101095807A - Chinese medicine preparation for treating diabetes skin pruritus - Google Patents
Chinese medicine preparation for treating diabetes skin pruritus Download PDFInfo
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- CN101095807A CN101095807A CNA2007101183527A CN200710118352A CN101095807A CN 101095807 A CN101095807 A CN 101095807A CN A2007101183527 A CNA2007101183527 A CN A2007101183527A CN 200710118352 A CN200710118352 A CN 200710118352A CN 101095807 A CN101095807 A CN 101095807A
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Abstract
The invention relates to a Chinese medicament for treating diabetic skin pruritus, which is prepared from more than ten kinds of Chinese medicinal herbs including poria cocos, alkanna tinctoria, honeysuckle flower and broom cypress fruit. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetic skin pruritus, is that a kind of diabetic skin pruritus for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetes are a kind of endocrinopathyes that are easy to infect, and can cause the various skin infringement.Skin is the active tissue of metabolism, and the metabolism disorder of diabetes makes pathogenic bacterium be easy to growth and breeding.So diabetic dermopathy becomes with venereal infection especially and sees more, and often finds diabetes because of pyogenic infection takes place skin repeatedly.According to the report of Gilgor and Lazarus, about 30% diabetics generation dermatosis.Pruritus is the common a kind of subjective symptoms of dermatosis.Have only skin pruritus clinically and do not have the primary lesion person is called pruritus, the branch of whole body and part can be arranged.Diabetics particularly more to be seen.The concurrent neuropathy of diabetics, the skin-nourishing obstacle, perspiration reduces, and because hyperglycemia causes that xerosis cutis, skin play bits.Because psychentonia, excited, anxiety, depression etc. can increase the weight of pruritus.Also can cause because of change such as environment, weather, season, temperature, humidity and with the strong soap of alkalescence etc.Female patient is often because of pudendum fungal infection, infusorian; The male is normal relevant with factors such as prostatitis, pudendum perspirations.
Primary disease mainly shows as whole body or limitation skin pruritus.The whole body pruritus begins to be the part, continues and then expands to whole body, can show as migration, paroxysmal, to attach most importance to night.Pruritus degree weight differs, and severe patient is often hemorrhagely just given up to grab.Local symptom based on around anus and the anus, perineum, women pudendum etc., local Chang Yin makes the skin thickening from the beginning of scratching.Pruritus degree and blood sugar level are proportionate, and the controlled pruritus of blood glucose can improve so that disappear.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic skin pruritus.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 parts of Cortex Dictamni of 1.5～6 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.1～2 part of 1.0～4 parts of Fructus Kochiae of 1.5～6 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
0.1～2 part of 0.1～2 part of Radix Saposhnikoviae of 1.5～6 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.1～1 part of 0.1～2 portion of Periostracum Cicadae of 1.5～6 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
The weight proportion of each raw material of optimization formula of the present invention is:
0.5～1.5 part of 1.5～2.5 parts of Cortex Dictamni of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 parts of Fructus Kochiae of 2.5～3.5 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
0.5～1.5 part of 0.5～1.5 part of Radix Saposhnikoviae of 2.5～3.5 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.3～0.7 part of 0.5～1.5 portion of Periostracum Cicadae of 2.5～3.5 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 parts of Cortex Dictamni of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 parts of Fructus Kochiae of 3 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
1 part of 1 part of Radix Saposhnikoviae of 3 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.5 part of 1 portion of Periostracum Cicadae of 3 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Flos Lonicerae property of medicine is sweet, and is cold.Attach to the lung and stomach meridians.Effect with heat-clearing and toxic substances removing.Can treat the heating of affection due to external wind and heat or epidemic febrile disease, heatstroke, toxic-heat and blood stasis, carbuncle furuncle, sore throat, multiple infectious disease etc.(the 1972nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Smilacis Glabrae property of medicine is sweet, light, and is flat.Return liver,kidney,spleen, stomach warp.Have removing damp-heat, let out turbid detoxifcation, the effect of easing joint movement.Can treat syphilis, stranguria with turbid discharge is had loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism etc.(the 124th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Arnebiae (Radix Lithospermi) property of medicine hardship, cold.GUIXIN, Liver Channel.Has removing heat from blood and promoting blood circulation, the effect of detoxifcation rash.Can treat haematemesis, epistaxis, hematuria, purpura, macule, measles, jaundice, carbuncle is scalded etc.(the 3272nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, large intestine channel.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Schizonepetae property of medicine suffering, little hardship, tepor.Return lung, Liver Channel.Have and dispel the wind, induce sweat, rash, hemostatic effect.Can treat cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, rubella, carbuncle, the skin ulcer scabies, epistaxis is spitted blood, and has blood in stool metrorrhagia, puerperal blood faints etc.(the 2112nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Dictamni property of medicine hardship, salty, cold.Return spleen, stomach warp.Has heat clearing and damp drying, dispelling wind for relieving itching, antidotal effect.Can treat the rubella eczema due to the wind heat noxious dampness, scabies, jaundice, rheumatism pyretic arthralgia etc.(the 1019th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Kochiae property of medicine hardship, cold.Return kidney, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of dispelling wind for relieving itching.Can treat dysuria, stranguria with turbid discharge, leukorrhagia, dysentery, rubella, eczema, scabies, skin pruritus, sore etc.(the 1137th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Periostracum Cicadae property of medicine is sweet, salty, cold.Return lung, Liver Channel.Has dispelling wind-heat, rash sore-throat relieving, the effect of expellingging wind and relieving convulsion.Can treat anemopyretic cold, laryngopharynx swelling and pain, the cough hoarseness, measles without adequate eruption, the rubella pruritus, the conjunctival congestion cataracta, infantile convulsion is twitched, tetanus etc.(the 3599th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, Radix Scrophulariae, Flos Lonicerae and Rhizoma Smilacis Glabrae; With Cortex Dictamni, Radix Sophorae Flavescentis, Radix Paeoniae Rubra, Radix Arnebiae (Radix Lithospermi) and Periostracum Cicadae is ministerial drug; With the Fructus Kochiae, Herba Schizonepetae and Radix Saposhnikoviae is adjuvant.All medicines are harmonious, and are total to the tool nourishing YIN and benefiting blood, the wind itching relieving effect of loosing.The treatment diabetic skin pruritus has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic skin pruritus of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, be rich in egg from matter in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic skin pruritus, and the prevention of diabetic skin pruritus is also had good effect, and the treatment diabetic skin pruritus has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic skin pruritus; Treatment diabetic skin pruritus patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two weeks is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 35%, and 9 examples that take a turn for the better account for 45%, and invalid 4 examples account for 20%, and total effective rate reaches 80%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 2 parts of Cortex Dictamni of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 parts of Fructus Kochiae of 3 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
1 part of 1 part of Radix Saposhnikoviae of 3 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.5 part of 1 portion of Periostracum Cicadae of 3 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic skin pruritus that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two weeks is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of diabetic skin pruritus is characterized in that it is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 parts of Cortex Dictamni of 1.5～6 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.1～2 part of 1.0～4 parts of Fructus Kochiae of 1.5～6 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
0.1～2 part of 0.1～2 part of Radix Saposhnikoviae of 1.5～6 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.1～1 part of 0.1～2 portion of Periostracum Cicadae of 1.5～6 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
2, a kind of Chinese medicine preparation for the treatment of diabetic skin pruritus according to claim 1, wherein the weight proportion of each raw material is:
0.5～1.5 part of 1.5～2.5 parts of Cortex Dictamni of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 parts of Fructus Kochiae of 2.5～3.5 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
0.5～1.5 part of 0.5～1.5 part of Radix Saposhnikoviae of 2.5～3.5 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.3～0.7 part of 0.5～1.5 portion of Periostracum Cicadae of 2.5～3.5 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
3, a kind of Chinese medicine preparation for the treatment of diabetic skin pruritus according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 parts of Cortex Dictamni of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 parts of Fructus Kochiae of 3 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Scrophulariae
1 part of 1 part of Radix Saposhnikoviae of 3 parts of Radix Sophorae Flavescentiss of Flos Lonicerae
0.5 part of 1 portion of Periostracum Cicadae of 3 portions of Herba Schizonepetae of Rhizoma Smilacis Glabrae.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183527A CN101095807A (en) | 2007-07-05 | 2007-07-05 | Chinese medicine preparation for treating diabetes skin pruritus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183527A CN101095807A (en) | 2007-07-05 | 2007-07-05 | Chinese medicine preparation for treating diabetes skin pruritus |
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| CN101095807A true CN101095807A (en) | 2008-01-02 |
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| CNA2007101183527A Pending CN101095807A (en) | 2007-07-05 | 2007-07-05 | Chinese medicine preparation for treating diabetes skin pruritus |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101396454B (en) * | 2007-09-26 | 2011-04-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN102755435A (en) * | 2012-07-12 | 2012-10-31 | 中国人民解放军第三O二医院 | Chinese medicinal preparation for treating cutaneous pruritus and preparation method thereof |
| CN103550638A (en) * | 2013-11-07 | 2014-02-05 | 孙丽 | Traditional Chinese medicine for treating skin itch with syndrome of superficies attacked by wind-heat |
| CN105106674A (en) * | 2015-10-12 | 2015-12-02 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine composition for treating senile skin pruritus and preparation method of composition |
| CN110638900A (en) * | 2019-10-01 | 2020-01-03 | 重庆第二师范学院 | Traditional Chinese medicine composition for treating pruritic skin diseases of children and preparation method thereof |
-
2007
- 2007-07-05 CN CNA2007101183527A patent/CN101095807A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101396454B (en) * | 2007-09-26 | 2011-04-06 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic skin pruritus |
| CN102755435A (en) * | 2012-07-12 | 2012-10-31 | 中国人民解放军第三O二医院 | Chinese medicinal preparation for treating cutaneous pruritus and preparation method thereof |
| CN102755435B (en) * | 2012-07-12 | 2014-12-17 | 中国人民解放军第三O二医院 | Chinese medicinal preparation for treating cutaneous pruritus and preparation method thereof |
| CN103550638A (en) * | 2013-11-07 | 2014-02-05 | 孙丽 | Traditional Chinese medicine for treating skin itch with syndrome of superficies attacked by wind-heat |
| CN103550638B (en) * | 2013-11-07 | 2015-04-22 | 青岛市市立医院 | Traditional Chinese medicine for treating skin itch with syndrome of superficies attacked by wind-heat |
| CN105106674A (en) * | 2015-10-12 | 2015-12-02 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine composition for treating senile skin pruritus and preparation method of composition |
| CN110638900A (en) * | 2019-10-01 | 2020-01-03 | 重庆第二师范学院 | Traditional Chinese medicine composition for treating pruritic skin diseases of children and preparation method thereof |
| CN110638900B (en) * | 2019-10-01 | 2021-08-17 | 重庆第二师范学院 | Traditional Chinese medicine composition for treating pruritic skin diseases of children and preparation method thereof |
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Open date: 20080102 |