CN101095748A - Chinese patent medicine for treating diabetic skin pruritus - Google Patents
Chinese patent medicine for treating diabetic skin pruritus Download PDFInfo
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- CN101095748A CN101095748A CNA2007101183508A CN200710118350A CN101095748A CN 101095748 A CN101095748 A CN 101095748A CN A2007101183508 A CNA2007101183508 A CN A2007101183508A CN 200710118350 A CN200710118350 A CN 200710118350A CN 101095748 A CN101095748 A CN 101095748A
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Abstract
The invention relates to a Chinese medicament for treating diabetic skin pruritus, which is prepared from more than ten kinds of Chinese medicinal herbs including fleece-flower root, prepared rehmannia root, dandelion and bark of peony root. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of diabetic skin pruritus, is that a kind of diabetic skin pruritus for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetes are a kind of endocrinopathyes that are easy to infect, and can cause the various skin infringement.Skin is the active tissue of metabolism, and the metabolism disorder of diabetes makes pathogenic bacterium be easy to growth and breeding.So diabetic dermopathy becomes with venereal infection especially and sees more, and often finds diabetes because of pyogenic infection takes place skin repeatedly.According to the report of Gilgor and Lazarus, about 30% diabetics generation dermatosis.Pruritus is the common a kind of subjective symptoms of dermatosis.Have only skin pruritus clinically and do not have the primary lesion person is called pruritus, the branch of whole body and part can be arranged.Diabetics particularly more to be seen.The concurrent neuropathy of diabetics, the skin-nourishing obstacle, perspiration reduces, and because hyperglycemia causes that xerosis cutis, skin play bits.Because psychentonia, excited, anxiety, depression etc. can increase the weight of pruritus.Also can cause because of change such as environment, weather, season, temperature, humidity and with the strong soap of alkalescence etc.Female patient is often because of pudendum fungal infection, infusorian; The male is normal relevant with factors such as prostatitis, pudendum perspirations.
Primary disease mainly shows as whole body or limitation skin pruritus.The whole body pruritus begins to be the part, continues and then expands to whole body, can show as migration, paroxysmal, to attach most importance to night.Pruritus degree weight differs, and severe patient is often hemorrhagely just given up to grab.Local symptom based on around anus and the anus, perineum, women pudendum etc., local Chang Yin makes the skin thickening from the beginning of scratching.Pruritus degree and blood sugar level are proportionate, and the controlled pruritus of blood glucose can improve so that disappear.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of diabetic skin pruritus.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 parts of Fructus Atriplicis Sibiricae of 1.5～6 parts of Radixs Astragali of Radix Rehmanniae Preparata
0.1～2 part of 1.0～4 portions of Herba Schizonepetae of 1.5～6 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.1～1 part of 1.0～4 parts of Fructus Cnidii of 1.0～4 parts of Radix Scutellariaes of Herba Taraxaci.
The weight proportion of each raw material of optimization formula of the present invention is:
0.5～1.5 part of 1.5～2.5 parts of Fructus Atriplicis Sibiricae of 2.5～3.5 parts of Radixs Astragali of Radix Rehmanniae Preparata
0.5～1.5 part of 1.5～2.5 portions of Herba Schizonepetae of 2.5～3.5 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.3～0.7 part of 1.5～2.5 parts of Fructus Cnidii of 1.5～2.5 parts of Radix Scutellariaes of Herba Taraxaci.
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 parts of Fructus Atriplicis Sibiricae of 3 parts of Radixs Astragali of Radix Rehmanniae Preparata
1 part of 2 portions of Herba Schizonepetae of 3 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
1 part of 2 parts of Cortex Moutan of 3 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.5 part of 2 parts of Fructus Cnidii of 2 parts of Radix Scutellariaes of Herba Taraxaci.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Taraxaci property of medicine hardship, sweet, cold.Return liver, stomach warp.Has heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.Can treat acute mastitis, lung abscess, acute appendicitis, mumps, scrofula, furuncle carbuncle toxin, conjunctival congestion and swelling pain, cat fever, cough, laryngopharynx swelling and pain, gastritis, enteritis, dysentery, hepatitis, cholecystitis, urinary tract infection, snake bite and insect sting, burn and scald etc.(the 3427th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Atriplicis Sibiricae property of medicine hardship, suffering, flat.Return liver, lung meridian.Have suppressing the hyperactive liver, resolving depression makes eye bright, the effect of dispeling the wind.Can treat headache, dizzy, distending pain in the chest and hypochondrium, distending pain of the breast ， mass in the abdomen, conjunctival congestion cataracta, rubella pruritus, vitiligo, carbuncle, scrofula etc.(the 1844th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Schizonepetae property of medicine suffering, little hardship, tepor.Return lung, Liver Channel.Have and dispel the wind, induce sweat, rash, hemostatic effect.Can treat cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, rubella, carbuncle, the skin ulcer scabies, epistaxis is spitted blood, and has blood in stool metrorrhagia, puerperal blood faints etc.(the 2112nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Cnidii property of medicine suffering, hardship, temperature.Return liver, kidney channel.Has warming the kidney to invigorate YANG, removing dampness and killing parasites, the effect of dispelling wind for relieving itching.Can treat impotence in male, woman's infertility, arthralgia chiefly caused by damp pathogen lumbago, cold-damp leukorrhagia, scrotum pruritus due to damp pathogen, rheumatic arthralgia, eczema, scabies etc.(the 3005th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", with Radix Rehmanniae Preparata, Radix Polygoni Multiflori with when being classified as monarch drug; With Herba Taraxaci, the Radix Astragali, Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Radix Scutellariae and Fructus Cnidii is ministerial drug; With Fructus Atriplicis Sibiricae, Herba Schizonepetae and Cortex Moutan is adjuvant.All medicines are harmonious, and are total to the tool benefiting QI and nourishing blood, the wind itching relieving effect of loosing.The treatment diabetic skin pruritus has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic skin pruritus of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic skin pruritus, and the prevention of diabetic skin pruritus is also had good effect, and the treatment diabetic skin pruritus has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic skin pruritus; Treatment diabetic skin pruritus patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two weeks is a course of treatment, take continuously three the course of treatment observe the curative effect.11 examples of fully recovering account for 61.11%, and 5 examples that take a turn for the better account for 27.78%, and invalid 2 examples account for 11.11%, and total effective rate reaches 88.89%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight;
1 part of 2 parts of Fructus Atriplicis Sibiricae of 3 parts of Radixs Astragali of Radix Rehmanniae Preparata
1 part of 2 portions of Herba Schizonepetae of 3 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
1 part of 2 parts of Cortex Moutan of 3 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.5 part of 2 parts of Fructus Cnidii of 2 parts of Radix Scutellariaes of Herba Taraxaci.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic skin pruritus that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two weeks is a course of treatment.
Claims (3)
1, a kind of Chinese patent medicine for the treatment of diabetic skin pruritus is characterized in that it is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 parts of Fructus Atriplicis Sibiricae of 1.5～6 parts of Radixs Astragali of Radix Rehmanniae Preparata
0.1～2 part of 1.0～4 portions of Herba Schizonepetae of 1.5～6 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.1～1 part of 1.0～4 parts of Fructus Cnidii of 1.0～4 parts of Radix Scutellariaes of Herba Taraxaci.
2, a kind of Chinese patent medicine for the treatment of diabetic skin pruritus according to claim 1, wherein the weight proportion of each raw material is:
0.5～1.5 part of 1.5～2.5 parts of Fructus Atriplicis Sibiricae of 2.5～3.5 parts of Radixs Astragali of Radix Rehmanniae Preparata
0.5～1.5 part of 1.5～2.5 portions of Herba Schizonepetae of 2.5～3.5 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.3～0.7 part of 1.5～2.5 parts of Fructus Cnidii of 1.5～2.5 parts of Radix Scutellariaes of Herba Taraxaci.
3, a kind of Chinese patent medicine for the treatment of diabetic skin pruritus according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 parts of Fructus Atriplicis Sibiricae of 3 parts of Radixs Astragali of Radix Rehmanniae Preparata
1 part of 2 portions of Herba Schizonepetae of 3 parts of Radix Saposhnikoviaes of Radix Polygoni Multiflori
1 part of 2 parts of Cortex Moutan of 3 parts of Radix Salviae Miltiorrhizaes of Radix Angelicae Sinensis
0.5 part of 2 parts of Fructus Cnidii of 2 parts of Radix Scutellariaes of Herba Taraxaci.
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| CNA2007101183508A CN101095748A (en) | 2007-07-05 | 2007-07-05 | Chinese patent medicine for treating diabetic skin pruritus |
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| CNA2007101183508A CN101095748A (en) | 2007-07-05 | 2007-07-05 | Chinese patent medicine for treating diabetic skin pruritus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101628057B (en) * | 2009-08-14 | 2011-04-13 | 南宁市维威制药有限公司 | Pharmaceutical composition for treating senile skin pruritus and preparation method thereof |
| CN105106674A (en) * | 2015-10-12 | 2015-12-02 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine composition for treating senile skin pruritus and preparation method of composition |
-
2007
- 2007-07-05 CN CNA2007101183508A patent/CN101095748A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101628057B (en) * | 2009-08-14 | 2011-04-13 | 南宁市维威制药有限公司 | Pharmaceutical composition for treating senile skin pruritus and preparation method thereof |
| CN105106674A (en) * | 2015-10-12 | 2015-12-02 | 临沂草之美医药科技有限公司 | Traditional Chinese medicine composition for treating senile skin pruritus and preparation method of composition |
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Open date: 20080102 |