CN101095872A - Chinese traditional medicine composition for treating anaphylactoid purpura nephritis - Google Patents
Chinese traditional medicine composition for treating anaphylactoid purpura nephritis Download PDFInfo
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- CN101095872A CN101095872A CNA2007101183264A CN200710118326A CN101095872A CN 101095872 A CN101095872 A CN 101095872A CN A2007101183264 A CNA2007101183264 A CN A2007101183264A CN 200710118326 A CN200710118326 A CN 200710118326A CN 101095872 A CN101095872 A CN 101095872A
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Abstract
The invention relates to a Chinese medicinal composition for treating allergic purpura nephritis, which is prepared from more than ten kinds of Chinese medicinal herbs including white atractylodes rhizome, astragalus root, Poria cocos and coix seed. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to treat the Chinese medicine composition of anaphy lactoid purpura nephritis, is that a kind of anaphy lactoid purpura nephritis for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Anaphylactoid purpura is to be the syndrome of feature with skin purpura, gastroenteritis haemorrhagica, arthritis and kidney damage, is a kind of general polyangitis relevant with immunity.The renal damage that anaphylactoid purpura causes claims anaphy lactoid purpura nephritis.The clinical symptoms weight differs, from simple urine examination unusually to the typical acute nephritic syndrome, nephrotic syndrome even renal failure.Hematuria (under naked eyes or the mirror) is its common performance, and Most patients is optimum, self-limited course is more than fully recovering in several weeks.But outbreak repeatedly or delay several months, several years person are arranged also.About 50% patient's course of disease is shown effect repeatedly.The order of severity of pathological change is depended in prognosis.The anaphy lactoid purpura nephritis sickness rate accounts for 20%～100% of patients with anaphylactoid purpura, domesticly is reported in 30%～50%, abroad have with the kidney biopsy be diagnostic criteria then sickness rate up to more than 90%.Any age of primary disease all can fall ill, and is more common in child and teenager, with 6～13 years old for the highest, gender's ratio is 1.5～3: 1, betides cold season well.Henoch Schonlein purpura nephritis belongs to Chinese medicine " hematuria ", " hematohidrosis ", " edema " sick categories such as " arthromyodynias ".The clinical manifestation of primary disease is: erythra, joint symptom, gastrointestinal symptom and other symptom.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as pathogenic wind toxic is invaded, the high Sheng of pyretic toxicity, the heat in blood of suffering from a deficiency of the kidney, asthenia of pulmonosplenic qi, deficiency of both QI and YIN, deficiency of spleen-YANG and kidneyYANG clinically outward, obtains very good effect.The traditional Chinese medical science and therapy of combining Chinese and Western medicine henoch Schonlein purpura nephritis have been received curative effect preferably in recent years, have represented fine prospect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine composition for the treatment of anaphy lactoid purpura nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radixs Astragali of 1.5～6 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.0～4 portions of Radix Paeoniae Albas of Semen Coicis
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 0.1～1 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
1.0～4 parts of 0.1～2 portion of Rhizoma Alismatis of 0.1～2 portion of Radix Rubiae of Semen Plantaginis.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radixs Astragali of 2.5～3.5 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 1.5～2.5 portions of Radix Paeoniae Albas of Semen Coicis
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 0.3～0.7 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
1.5～2.5 parts of 0.5～1.5 portion of Rhizoma Alismatis of 0.5～1.5 portion of Radix Rubiae of Semen Plantaginis.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Radix Codonopsis of 2 portions of Radix Paeoniae Albas of Semen Coicis
2 parts of 2 parts of Radix Angelicae Sinensis of 0.5 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
2 parts of 1 portion of Rhizoma Alismatis of 1 portion of Radix Rubiae of Semen Plantaginis.
Drug action mechanism among the present invention is as follows:
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Coicis property of medicine is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.Has the dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.(the 3725th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Rubiae property of medicine hardship, cold.Return liver, heart channel.Has cooling blood for hemostasis, the effect of blood circulation promoting and blood stasis dispelling.Can treat heat in blood spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid are swollen etc.(the 2115th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Atractylodis Macrocephalae (parched), Radix Aconiti Lateralis Preparata, Poria and the Radix Astragali; With the Radix Paeoniae Alba, Radix Codonopsis, Semen Coicis, Radix Codonopsis, Radix Angelicae Sinensis and Rhizoma Alismatis is ministerial drug; With Semen Plantaginis and Radix Rubiae is adjuvant.All medicines are harmonious, and are total to the tool warming YANG and strengthening the spleen, the effect of promote the circulation of qi and water.The treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment anaphy lactoid purpura nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat anaphy lactoid purpura nephritis, and the prevention of anaphy lactoid purpura nephritis is also had good effect, and the treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment anaphy lactoid purpura nephritis; Treatment anaphy lactoid purpura nephritis patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.12 examples of fully recovering account for 60%, and 6 examples that take a turn for the better account for 30%, and invalid 2 examples account for 10%, and total effective rate reaches 90%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Radix Codonopsis of 2 portions of Radix Paeoniae Albas of Semen Coicis
2 parts of 2 parts of Radix Angelicae Sinensis of 0.5 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
2 parts of 1 portion of Rhizoma Alismatis of 1 portion of Radix Rubiae of Semen Plantaginis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment anaphy lactoid purpura nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, the Chinese medicine composition of treatment anaphy lactoid purpura nephritis is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radixs Astragali of 1.5～6 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.0～4 portions of Radix Paeoniae Albas of Semen Coicis
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 0.1～1 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
1.0～4 parts of 0.1～2 portion of Rhizoma Alismatis of 0.1～2 portion of Radix Rubiae of Semen Plantaginis.
2, the Chinese medicine composition of treatment anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Radixs Astragali of 2.5～3.5 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 1.5～2.5 portions of Radix Paeoniae Albas of Semen Coicis
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 0.3～0.7 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
1.5～2.5 parts of 0.5～1.5 portion of Rhizoma Alismatis of 0.5～1.5 portion of Radix Rubiae of Semen Plantaginis.
3, the Chinese medicine composition of treatment anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Radix Codonopsis of 2 portions of Radix Paeoniae Albas of Semen Coicis
2 parts of 2 parts of Radix Angelicae Sinensis of 0.5 part of Radix Salviae Miltiorrhizae of Radix Aconiti Lateralis Preparata
2 parts of 1 portion of Rhizoma Alismatis of 1 portion of Radix Rubiae of Semen Plantaginis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183264A CN101095872A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating anaphylactoid purpura nephritis |
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| CNA2007101183264A CN101095872A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating anaphylactoid purpura nephritis |
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| CN101095872A true CN101095872A (en) | 2008-01-02 |
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| CNA2007101183264A Pending CN101095872A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating anaphylactoid purpura nephritis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772731A (en) * | 2012-06-30 | 2012-11-14 | 王少伟 | Traditional Chinese medicine used for treating spleen-kidney yang deficiency-type chronic nephritis |
| CN103041183A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof |
| ES2935433A1 (en) * | 2021-09-06 | 2023-03-06 | Zongzhi Detection Tech Dev Ltd | A COMPOSITION OF TRADITIONAL CHINESE MEDICINE (Machine-translation by Google Translate, not legally binding) |
-
2007
- 2007-07-05 CN CNA2007101183264A patent/CN101095872A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772731A (en) * | 2012-06-30 | 2012-11-14 | 王少伟 | Traditional Chinese medicine used for treating spleen-kidney yang deficiency-type chronic nephritis |
| CN103041183A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof |
| ES2935433A1 (en) * | 2021-09-06 | 2023-03-06 | Zongzhi Detection Tech Dev Ltd | A COMPOSITION OF TRADITIONAL CHINESE MEDICINE (Machine-translation by Google Translate, not legally binding) |
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Open date: 20080102 |