CN101085128A - Traditional Chinese medicine for treating chronic renal failure - Google Patents

Traditional Chinese medicine for treating chronic renal failure Download PDF

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Publication number
CN101085128A
CN101085128A CNA2007101179254A CN200710117925A CN101085128A CN 101085128 A CN101085128 A CN 101085128A CN A2007101179254 A CNA2007101179254 A CN A2007101179254A CN 200710117925 A CN200710117925 A CN 200710117925A CN 101085128 A CN101085128 A CN 101085128A
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chinese medicine
radix
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traditional chinese
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating chronic kidney failure which is prepared from more than ten kinds of Chinese medicinal herbs including epimeddium, tortoise shell, cyathula root and doddor seed.

Description

A kind of Chinese medicine for the treatment of chronic kidney hypofunction
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of chronic kidney hypofunction, is that a kind of chronic kidney hypofunction for the treatment of is the Chinese medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Chronic renal failure (chronic kidney hypofunction) is because the result of kidney damage that a variety of causes causes and the deterioration of carrying out property, body is at the excretion metabolism product, regulate water, electrolyte, acid-base balance, and the clinical syndrome that gets muddled of aspects such as the generation of some endocrine activity material and deactivation.Chronic kidney hypofunction belongs to categories such as " difficulty in urination ", " obstruction and rejection ", " edema ", " asthenia " in the traditional Chinese medical science.Chronic kidney hypofunction can be by multiple kidney disease development such as edema, stranguria, hematuria.The traditional Chinese medical science thinks that with the passing of time various nephropathy, undermine each function, and based on the spleen damage of suffering from a deficiency of the kidney, the state of an illness progressively develops and aggravates disease, and causes the positive deficiency of vital energy to decline at last, and turbid pathogen, blood stasis are stopped up the kidney network that stagnates, cause kidney to lose out entire function, the retention of turbid damp uremic is in body, and the initiation primary disease.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as spleen deficiency of kidney-QI, deficiency of spleen-YANG and kidneyYANG, the hepatic and renal YIN deficiency, deficiency of both YIN and YANG clinically, obtains very good effect.The research of Chinese medicine chronic kidney hypofunction has had bigger progress.Theoretical side, vital QI being weakened and pathogen being violent, the pathogenic characteristic of carrying throughout must be known together.Differential diagnosis in tcm opinion control Chinese medicine decoction in the delaying chronic kidney hypofunction progress, improve clinical symptoms and cooperate hemodialysis, reduce the dialysis complication, improve dialysis patient life quality aspect and all obtained certain effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine for the treatment of chronic kidney hypofunction.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Radix Rehmanniae of 1.5~6 portions of Cortex Cinnamomis of Herba Epimedii
1.0~4 parts of 1.0~4 parts of Semen Cuscutae of 1.5~6 parts of Poria of Radix Cyathulae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 portion of Rhizoma Alismatis of Fructus Corni
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae of 2.5~3.5 portions of Cortex Cinnamomis of Herba Epimedii
1.5~2.5 parts of 1.5~2.5 parts of Semen Cuscutae of 2.5~3.5 parts of Poria of Radix Cyathulae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 portion of Rhizoma Alismatis of Fructus Corni
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Radix Rehmanniae of 3 portions of Cortex Cinnamomis of Herba Epimedii
2 parts of 2 parts of Semen Cuscutae of 3 parts of Poria of Radix Cyathulae
1 part of 2 portions of Semen Plantaginis of 3 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 portion of Rhizoma Alismatis of Fructus Corni
Drug action mechanism among the present invention is as follows:
Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Carapax Et Plastrum Testudinis property of medicine is salty, sweet, is slightly cold.Return liver, kidney, heart channel.Has nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, the effect of consolidating channel for hemostasis.Can treat deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and wriggling of the limbs, a little less than the muscles and bones flaccidity, children's's halogen door does not conform to, and the palpitation with fear insomnia is forgetful, menorrhagia, metrorrhagia and metrostaxis.(the 1608th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Aconiti Lateralis Preparata, Herba Epimedii, Radix Cyathulae and Carapax Et Plastrum Testudinis; With Cortex Cinnamomi, Radix Rehmanniae, Fructus Corni, Poria, the Radix Astragali and Semen Cuscutae is ministerial drug; With Rhizoma Alismatis and Semen Plantaginis is adjuvant.All medicines are harmonious, and the tool temperature is held up Yuanyang, the effect that tonification is Kidney-Yin altogether.The treatment chronic kidney hypofunction has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment chronic kidney hypofunction of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat chronic kidney hypofunction, and the prevention of chronic kidney hypofunction is also had good effect, and the treatment chronic kidney hypofunction has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chronic kidney hypofunction; Treatment chronic kidney hypofunction patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.Produce effects 10 examples account for 40%, and effective 11 examples account for 44%, and invalid 4 examples account for 16%, and total effective rate reaches 84%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Radix Rehmanniae of 3 portions of Cortex Cinnamomis of Herba Epimedii
2 parts of 2 parts of Semen Cuscutae of 3 parts of Poria of Radix Cyathulae
1 part of 2 portions of Semen Plantaginis of 3 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 portion of Rhizoma Alismatis of Fructus Corni.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chronic kidney hypofunction that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine for the treatment of chronic kidney hypofunction is characterized in that it is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Radix Rehmanniae of 1.5~6 portions of Cortex Cinnamomis of Herba Epimedii
1.0~4 parts of 1.0~4 parts of Semen Cuscutae of 1.5~6 parts of Poria of Radix Cyathulae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 portion of Rhizoma Alismatis of Fructus Corni.
2, a kind of Chinese medicine for the treatment of chronic kidney hypofunction according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae of 2.5~3.5 portions of Cortex Cinnamomis of Herba Epimedii
1.5~2.5 parts of 1.5~2.5 parts of Semen Cuscutae of 2.5~3.5 parts of Poria of Radix Cyathulae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 portion of Rhizoma Alismatis of Fructus Corni.
3, a kind of Chinese medicine for the treatment of chronic kidney hypofunction according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Radix Rehmanniae of 3 portions of Cortex Cinnamomis of Herba Epimedii
2 parts of 2 parts of Semen Cuscutae of 3 parts of Poria of Radix Cyathulae
1 part of 2 portions of Semen Plantaginis of 3 parts of Radixs Astragali of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 portion of Rhizoma Alismatis of Fructus Corni.
CNA2007101179254A 2007-06-26 2007-06-26 Traditional Chinese medicine for treating chronic renal failure Pending CN101085128A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101843697B (en) * 2009-10-16 2011-12-21 北京绿源求证科技发展有限责任公司 Chinese medicament for treating chronic kidney failure
CN104873841A (en) * 2015-06-11 2015-09-02 济南方宇文化传媒有限公司 Spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure and preparation method thereof
CN105267614A (en) * 2015-10-29 2016-01-27 张相才 Traditional Chinese medicine composition for preventing and treating uremia and preparation method thereof
CN105596661A (en) * 2016-01-22 2016-05-25 贵州省麻江鸿翔中药材科技有限公司 Traditional Chinese medicine prescription for treating chronic renal failure

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101843697B (en) * 2009-10-16 2011-12-21 北京绿源求证科技发展有限责任公司 Chinese medicament for treating chronic kidney failure
CN104873841A (en) * 2015-06-11 2015-09-02 济南方宇文化传媒有限公司 Spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure and preparation method thereof
CN105267614A (en) * 2015-10-29 2016-01-27 张相才 Traditional Chinese medicine composition for preventing and treating uremia and preparation method thereof
CN105596661A (en) * 2016-01-22 2016-05-25 贵州省麻江鸿翔中药材科技有限公司 Traditional Chinese medicine prescription for treating chronic renal failure

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Open date: 20071212