CN101116709A - Chinese traditional medicine composition for treating non-gonococcal urethritis - Google Patents

Abstract

The invention relates to a Chinese crude drug composite for treating nongonococcal urethritis which takes more than 10 species of Chinese herbal medicines as raw materials, such as dodder seed, desertliving cistanche herb, morinda root, short-horned epimedium herb and so on. The invention has the effects of invigorating the kidney and spleen, dredging stranguria and dissolving turbidity. The invention is developed based on traditional Chinese medicine dialectical cure and combined with latest modern technological research findings. The invention aims to provide a Chinese crude drug composite for treating nongonococcal urethritis. The invention has the characteristics of preonunced curative effect, safety and convenience, non-toxic side effects and low price.

Description

A kind of Chinese medicine composition for the treatment of nongonococcal urethritis

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of nongonococcal urethritis, is that a kind of nongonococcal urethritis for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Nongonococcal urethritis is the urethritis that is caused by other pathogen beyond the Diplococcus gonorrhoeae, it is a kind of sexually transmitted disease (STD), the performance of urethritis is arranged clinically, but in urethral secretions, can not find out gonococcus, wherein also comprise the persistent gonorrhea posterior urethritis of gonorrhea healing back symptom.Because the women not only has the inflammation of urethra when suffering from primary disease, and the inflammation of reproductive tract such as cervicitis is arranged, therefore can be described as again " non-gonococcal urogenital infections ".Main clinical manifestation is urethral orifice discomfort, dysurea, urgent micturition, dysuria, and the visible leucorrhea of women is many etc.Find that in clinical because Drug resistance, the broad ectrum antibiotic therapeutic effect is more and more lower.

Nongonococcal urethritis belongs to the traditional Chinese medical science " stranguria ", " it is turbid to drown ", " nebulousurine ", and the women then belongs to " leukorrhagia ", " pudendal pruritus " etc.

Chinese medicine thinks that nongonococcal urethritis and sexual life are unclean, directly or indirectly experiences special foul heresy, leads to damp and hotly, and the damp and hot malicious heresy knot of fighting is invaded the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the multiple abscess bladder, and the smoked urethra that burns, and make bladder qi dysfunction, and disturbance in water passage, urinary catheter (road) blocks relevant; Or because of stagnation of QI due to depression of the liver, with the passing of time strongly fragrant and fire-transformation is invaded bladder down, makes gasification not all right, disturbance in water passage and be pouring; Also can be because of impairment of the kidney due to indulgence in sexual activities or damp and hot evil poison by the internal organs superinverse to dirty, injure kidney qi, the prolonged illness imapirment of the spleen and stomach, deficiency of spleen and stomach, it is not normal to gasify, and can not take the photograph to receive fat and stranguria with turbid discharge.The state of an illness is with the passing of time then drenched body void for a long time, and impairment caused by overstrain is excessive, or poison of drug hinders, and decreases cloudy consumption gas so that deficiency of spleen and stomach, and functioning of bladder is had no right, and damp is loved for a long time.The traditional Chinese medical science is divided at the treatment nongonococcal urethritis: the dialectical treatments of disease type such as damp invasion of lower energizer, stagnation of QI due to depression of the liver, the hepatic and renal YIN deficiency, deficiency of spleen and stomach obtain effect preferably, and do not recur.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of nongonococcal urethritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

1.5～6 parts in 1.5～6 parts of Poria of 1.5～6 parts of Herba Epimedii of Radix Morindae Officinalis

1.0～4 parts of 1.0～4 parts of Radixs Astragali of 1.0～4 parts of Herba Cistanches of Semen Cuscutae

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Cortexs Eucommiae of Fructus Lycii

0.1～2 part of 0.1～2 portion of Rhizoma Dioscoreae of 0.1～2 portion of Semen Plantaginis of Radix Cyathulae.

The weight proportion of each crude drug of optimization formula of the present invention is:

2.5～3.5 parts in 2.5～3.5 parts of Poria of 2.5～3.5 parts of Herba Epimedii of Radix Morindae Officinalis

1.5～2.5 parts of 1.5～2.5 parts of Radixs Astragali of 1.5～2.5 parts of Herba Cistanches of Semen Cuscutae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Cortexs Eucommiae of Fructus Lycii

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Dioscoreae of 0.5～1.5 portion of Semen Plantaginis of Radix Cyathulae.

The weight proportion of each crude drug of optimum formula of the present invention is:

3 parts in 3 parts of Poria of 3 parts of Herba Epimedii of Radix Morindae Officinalis

2 parts of 2 parts of Radixs Astragali of 2 parts of Herba Cistanches of Semen Cuscutae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Cortexs Eucommiae of Fructus Lycii

1 part of 1 portion of Rhizoma Dioscoreae of 1 portion of Semen Plantaginis of Radix Cyathulae.

Drug action mechanism among the present invention is as follows:

Radix Morindae Officinalis nature and flavor suffering, sweet, tepor.Return liver, kidney channel.Effect with kidney-replenishing, strengthening bone and muscle, wind-damp dispelling.Can treat impotence and seminal emission, cold womb is infertile, menoxenia, and cold and pain in the lower abdomen, rheumatic arthralgia, the muscles and bones flaccidity is soft etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 350th page).

Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Cistanches property of medicine is sweet, salty, temperature.Return kidney, large intestine channel.Has kidney-replenishing, benefiting essence-blood, the effect in intestine moistening road.Can treat the sexual impotence of kidney yang deficiency, asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, the lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation etc.(the 1226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Astragali nature and flavor are sweet, warm.Return lung, spleen channel.Have benefit and defend consolidating superficial resistance, inducing diuresis to remove edema, poison holding, the effect of granulation promoting.That can treat that internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle do not burst or burst does not hold back and the disease of all weakness of QI blood deficiency etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1074th page).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Has diuresis, the effect of clearing away damp-heat.Can treat dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia etc.(the 184th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Sweet, the little hardship of Radix Cyathulae nature and flavor, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Morindae Officinalis, Herba Epimedii and Poria; With Semen Cuscutae, Herba Cistanches, the Radix Astragali, Fructus Lycii, the Cortex Eucommiae and Rhizoma Alismatis is ministerial drug; With Radix Cyathulae, Semen Plantaginis and Rhizoma Dioscoreae is adjuvant.All medicines are harmonious, and are total to the tool kidney and spleen invigorating, the effect that treating stranguriaization is turbid.The treatment nongonococcal urethritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment nongonococcal urethritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat nongonococcal urethritis, and the prevention of nongonococcal urethritis is also had good effect, and the treatment nongonococcal urethritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment nongonococcal urethritis.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment nongonococcal urethritis; Treatment nongonococcal urethritis patient 22 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 17 examples and account for 77.27%, 3 examples that take a turn for the better account for 13.64%, and more 2 examples do not account for 9.09%, and total effective rate reaches 90.91%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

3 parts in 3 parts of Poria of 3 parts of Herba Epimedii of Radix Morindae Officinalis

2 parts of 2 parts of Radixs Astragali of 2 parts of Herba Cistanches of Semen Cuscutae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Cortexs Eucommiae of Fructus Lycii

1 part of 1 portion of Rhizoma Dioscoreae of 1 portion of Semen Plantaginis of Radix Cyathulae.

Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment nongonococcal urethritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. Chinese medicine composition for the treatment of nongonococcal urethritis is characterized in that it is made by following raw materials by weight proportions:

1.5～6 parts in 1.5～6 parts of Poria of 1.5～6 parts of Herba Epimedii of Radix Morindae Officinalis

1.0～4 parts of 1.0～4 parts of Radixs Astragali of 1.0～4 parts of Herba Cistanches of Semen Cuscutae

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Cortexs Eucommiae of Fructus Lycii

0.1～2 part of 0.1～2 portion of Rhizoma Dioscoreae of 0.1～2 portion of Semen Plantaginis of Radix Cyathulae.

2. a kind of Chinese medicine composition for the treatment of nongonococcal urethritis according to claim 1, wherein the weight proportion of each crude drug is:

2.5～3.5 parts in 2.5～3.5 parts of Poria of 2.5～3.5 parts of Herba Epimedii of Radix Morindae Officinalis

1.5～2.5 parts of 1.5～2.5 parts of Radixs Astragali of 1.5～2.5 parts of Herba Cistanches of Semen Cuscutae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Cortexs Eucommiae of Fructus Lycii

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Dioscoreae of 0.5～1.5 portion of Semen Plantaginis of Radix Cyathulae.

3. a kind of Chinese medicine composition for the treatment of nongonococcal urethritis according to claim 1, wherein the weight proportion of each crude drug is:

3 parts in 3 parts of Poria of 3 parts of Herba Epimedii of Radix Morindae Officinalis

2 parts of 2 parts of Radixs Astragali of 2 parts of Herba Cistanches of Semen Cuscutae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Cortexs Eucommiae of Fructus Lycii

1 part of 1 portion of Rhizoma Dioscoreae of 1 portion of Semen Plantaginis of Radix Cyathulae.