CN101085158A - Traditional Chinese medicine for treating interstitial nephritis - Google Patents

Traditional Chinese medicine for treating interstitial nephritis Download PDF

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Publication number
CN101085158A
CN101085158A CNA2007101179184A CN200710117918A CN101085158A CN 101085158 A CN101085158 A CN 101085158A CN A2007101179184 A CNA2007101179184 A CN A2007101179184A CN 200710117918 A CN200710117918 A CN 200710117918A CN 101085158 A CN101085158 A CN 101085158A
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parts
chinese medicine
radix
interstitial nephritis
portions
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CNA2007101179184A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101179184A priority Critical patent/CN101085158A/en
Publication of CN101085158A publication Critical patent/CN101085158A/en
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Abstract

The invention relates to a Chinese medicament for treating chronic interstitial nephritis which is prepared from more than ten kinds of Chinese medicinal herbs including epimeddium, astragalus root, doddor seed and deglued antler powder.

Description

The Chinese medicine of treatment chronic interstitial nephritis
Technical field
The present invention relates to treat the Chinese medicine of chronic interstitial nephritis, is that a kind of chronic interstitial nephritis for the treatment of is the Chinese medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Chronic interstitial nephritis is based on one group of chronic renal disease that the kidney ID becomes and renal tubular function is damaged, and with renal tubules small molecular protein urine, small amounts of cells and cast are with the xerostomia polydipsia clinically, polyuria, or loss of appetite, abdominal distention, nausea and vomiting, anemia, or myasthenia, paralysis, collapse from physical exhaustion arrhythmia, or frequent micturition, urgent micturition, dysurea, or lumbago, abdominal colic, hematuria has slough etc. to be main performance in the urine.According to clinical manifestation, chronic interstitial nephritis is the category such as " quenching one's thirst ", " stranguria caused by overstrain " of similar Chinese medicine then.The formation of chronic interstitial nephritis is many by the five internal organs weakness, and the deficiency of the kidney oligospermia experiences damp and hot, malicious evil in addition, so that kidney mistake folding, the gasification imbalance, and the defeated cloth, separating clear and excreting turbid and the discrepancy of water liquid that cause water Tianjin and cereal nutrient do not follow Chang Dao; Nephropathy and spleen, essence of water and grain can not be changed promoting generation of vital essence and blood, the defeated cloth imbalance of lifting, then the cereal nutrient mistake degree that leaks; Nephropathy and liver, liver blood is not hidden, and the muscle arteries and veins loses supports; With the passing of time disease prolongs, and then healthy energy is also hindered, and turbid dampization is given birth to.The traditional Chinese medical science is divided damp and hot being reluctant to leave clinically, and be impairment of the kidney the moon, evil poison of consumption is impairment of the kidney, deficiency of both QI and YIN, deficiency of liver-blood, and priming liver-wind, deficiency of spleen-YANG and kidneyYANG, disease type Coryza Treated by Syndrome Differentiation such as water retention obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine for the treatment of chronic interstitial nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Cornu Cervi Degelatinatums of 1.5~6 parts of Herba Epimedii of the Radix Astragali
1.0~4 parts of 1.0~4 portions of Radix Cyathulaes of 1.0~4 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.0~4 parts of Semen Cuscutae of Rhizoma Alismatis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of Cortex Eucommiae of Cortex Cinnamomi.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Cornu Cervi Degelatinatums of 2.5~3.5 parts of Herba Epimedii of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 portions of Radix Cyathulaes of 1.5~2.5 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 1.5~2.5 parts of Semen Cuscutae of Rhizoma Alismatis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of Cortex Eucommiae of Cortex Cinnamomi.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Cornu Cervi Degelatinatums of 3 parts of Herba Epimedii of the Radix Astragali
2 parts of 2 portions of Radix Cyathulaes of 2 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
1 part of 2 portions of Semen Plantaginis of 2 parts of Semen Cuscutae of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Cortex Eucommiae of Cortex Cinnamomi.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Cornu Cervi Degelatinatum property of medicine is salty, puckery, temperature.Return kidney, Liver Channel.Has reinforcing the kidney and supporting YANG, anastaltic effect.Can treat emission due to deficiency of the kidney, night sweat, anorexia and loose stool, chronic diarrhea chronic dysentery, metrorrhagia, leukorrhagia, frequent micturition, the enuresis, dribble of urine, skin infection disunion of a specified duration, wound hemorrhage etc.(the 3118th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Aconiti Lateralis Preparata, the Radix Astragali, Herba Epimedii and Cornu Cervi Degelatinatum; With Cortex Cinnamomi, Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Radix Cyathulae, Semen Cuscutae and Rhizoma Alismatis is ministerial drug; With the Semen Plantaginis and the Cortex Eucommiae is adjuvant.All medicines are harmonious, and are total to tool temperature compensation Liver and kidney, the effect of promote the circulation of qi and water.The treatment chronic interstitial nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment chronic interstitial nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat chronic interstitial nephritis, and the prevention of chronic interstitial nephritis is also had good effect, and the treatment chronic interstitial nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chronic interstitial nephritis; Treatment chronic interstitial nephritis patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 38.89%, and 9 examples that take a turn for the better account for 50%, and more 2 examples do not account for 11.11%, and total effective rate reaches 88.89%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Cornu Cervi Degelatinatums of 3 parts of Herba Epimedii of the Radix Astragali
2 parts of 2 portions of Radix Cyathulaes of 2 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
1 part of 2 portions of Semen Plantaginis of 2 parts of Semen Cuscutae of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Cortex Eucommiae of Cortex Cinnamomi.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chronic interstitial nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine of treatment chronic interstitial nephritis is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Cornu Cervi Degelatinatums of 1.5~6 parts of Herba Epimedii of the Radix Astragali
1.0~4 parts of 1.0~4 portions of Radix Cyathulaes of 1.0~4 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.0~4 parts of Semen Cuscutae of Rhizoma Alismatis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of Cortex Eucommiae of Cortex Cinnamomi.
2, the Chinese medicine of treatment chronic interstitial nephritis according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Cornu Cervi Degelatinatums of 2.5~3.5 parts of Herba Epimedii of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 portions of Radix Cyathulaes of 1.5~2.5 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 1.5~2.5 parts of Semen Cuscutae of Rhizoma Alismatis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of Cortex Eucommiae of Cortex Cinnamomi.
3, the Chinese medicine of treatment chronic interstitial nephritis according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Cornu Cervi Degelatinatums of 3 parts of Herba Epimedii of the Radix Astragali
2 parts of 2 portions of Radix Cyathulaes of 2 parts of Radix Rehmanniae Preparata of Rhizoma Dioscoreae
1 part of 2 portions of Semen Plantaginis of 2 parts of Semen Cuscutae of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Cortex Eucommiae of Cortex Cinnamomi.
CNA2007101179184A 2007-06-26 2007-06-26 Traditional Chinese medicine for treating interstitial nephritis Pending CN101085158A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933296A (en) * 2014-04-23 2014-07-23 逄海玲 Traditional Chinese medicine for treating chromic glomerulonephritis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933296A (en) * 2014-04-23 2014-07-23 逄海玲 Traditional Chinese medicine for treating chromic glomerulonephritis

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Open date: 20071212