CN101129736A - Traditional Chinese medicine composition for treating climacteric syndrome - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating climacteric syndrome which is prepared from more than ten kinds of Chinese medicinal herbs including sweetgum fruit, motherwort, spatholobus stem and ligustrum japonicum. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine composition of treatment climacteric syndrome

Technical field

The present invention relates to treat a kind of Chinese medicine composition of climacteric syndrome, is that a kind of climacteric syndrome for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Even climacteric syndrome is meant that the women menoxenia occurs in one period before and after the menopause, warms sweating, dysphoria with feverish sensation in the chest palms and soles, dizziness and tinnitus, palpitation and insomnia, fidgety irritability, pelvic bone is miserable, skin numbness is scratchy or have ant to climb the symptoms relevant with menopause such as sense, hypomnesis, edema loose stool abnormal emotion-thought, is called climacteric syndrome.Be because women's menopause front and back gonad generation degenerative change (comprising that menopause is preceding because of destroying bilateral ovaries behind excision bilateral ovaries or the radiotherapy), make the balance restricting relation disorder between the hypothalamic pituitary gonadal axis, and then cause due to the pathological change of body autonomic nervous dysfunction, sexual dysfunction.Climacteric syndrome is a common gynecological disease, its sickness rate is about 85%, wherein 60% patient has the sense of flushing hectic fever, women about 70%～80% has menoxenia, and be main symptom with autonomic nervous system dysfunction in various degree, the duration of symptoms that has is shorter, can oneself control, some then occur repeatedly symptom reach 5～10 surplus the year.Climacteric syndrome belongs to the category of " pre-postmenstrual syndromes ".According to its clinical manifestation stress difference, its category such as " cardiopalmus ", " insomnia ", " dizzy ", " headache ", " hysteria ", " edema ", " metrorrhagia ", " menorrhagia " that belong to Chinese medicine is carried out dialectical executing controls.Treatment focuses on transfers the tonifying kidney-yin kidney yang.Deficiency of the kidney yin person nourishing kidney tonifying YIN, insufficiency of kidney-YANG person the kidney warming invigorating YANG makes it reach relative balance on new basis.To menstrual disturbance patients, as few, not have and can transfer week through the frequency shower through measuring, the control menstrual blood volume is treated its exhausted naturally ending.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of climacteric syndrome.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 portions of Caulis Spatholobis of Radix Astragali

1.0～4 parts of 1.0～4 portions of Radix Paeoniae Albas of 1.0～4 parts of Concha Margaritiferas of Radix Morindae Officinalis

0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Fructus Ligustri Lucidi of Herba Leonuri

0.1～2 part of 0.1～2 portion of Rhizoma Cyperi of 1.0～4 parts of Fructus Liquidambaris of Cortex Albiziae.

The weight proportion of each crude drug of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 portions of Caulis Spatholobis of Radix Astragali

1.5～2.5 parts of 1.5～2.5 portions of Radix Paeoniae Albas of 1.5～2.5 parts of Concha Margaritiferas of Radix Morindae Officinalis

0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Fructus Ligustri Lucidi of Herba Leonuri

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Cyperi of 1.5～2.5 parts of Fructus Liquidambaris of Cortex Albiziae.

The weight proportion of each crude drug of optimum formula of the present invention is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 portions of Caulis Spatholobis of Radix Astragali

2 parts of 2 portions of Radix Paeoniae Albas of 2 parts of Concha Margaritiferas of Radix Morindae Officinalis

1 part of 2 parts of Radix Bupleuri of 2 parts of Fructus Ligustri Lucidi of Herba Leonuri

1 part of 1 portion of Rhizoma Cyperi of 2 parts of Fructus Liquidambaris of Cortex Albiziae.

Drug action mechanism among the present invention is as follows:

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Caulis Spatholobi property of medicine hardship, little sweet, temperature.Return liver, kidney channel.Has relaxing muscles and tendons to promote blood circulation, the effect of nourishing blood for regulating menstruation.Can treat numb hand and foot, quadriplegia, rheumatic arthralgia, anemia, menoxenia, dysmenorrhea, amenorrhea etc.(the 1689th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Cortex Albiziae property of medicine is sweet, bitter, and is flat.GUIXIN, spleen channel.Have Shu Yu, calm the nerves, regulate the flow of vital energy, make eye bright, demountable effect.Can treat melancholy insomnia.Irritability, forgetful, uncomfortable in chest indigestion and loss of appetite, wind-fire ophthalmic, blurring of vision, lumbago traumatic pain etc.(the 1296th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Concha Margaritifera property of medicine is sweet, salty, and is cold.Return liver, heart channel.Has suppressing the hyperactive liver and subsiding YANG, the arresting convulsion of calming the nerves, the effect of liver heat removing and eyesight improving.It is dizzy to treat headache, palpitation and insomnia, demented infantile convulsion, liver-heat conjunctival congestion, pterygium etc.(the 2103rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Liquidambaris property of medicine hardship, flat.Return liver, urinary bladder channel.Has dispelling, collateral-activating, the effect of diuretic dehumidifying.Can treat rheumatic arthralgia, wither muscle knot of limb, epigastric pain, amenorrhea, galactostasis, edema, eczema etc.(the 3470th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali, Caulis Spatholobi and the Rhizoma Anemarrhenae; With Radix Morindae Officinalis, Herba Leonuri, Cortex Albiziae, Concha Margaritifera, Fructus Ligustri Lucidi and the Radix Paeoniae Alba is ministerial drug; With Fructus Liquidambaris, Radix Bupleuri and Rhizoma Cyperi is adjuvant.All medicines are harmonious, and are total to the tool Replenishing QI and nourishing YIN, the effect of blood circulation and channel invigorating.The treatment climacteric syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment climacteric syndrome of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat climacteric syndrome, and the prevention of climacteric syndrome is also had good effect, and the treatment climacteric syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing medicine of the present invention, as follows through clinical test results to treatment treatment of climacteric syndrome effect; Treatment climacteric syndrome patient 22 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.14 examples of fully recovering account for 63.63%, and 7 examples that take a turn for the better account for 31.82%, and more 1 example does not account for 4.55%, and total effective rate reaches 95.45%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 portions of Caulis Spatholobis of Radix Astragali

2 parts of 2 portions of Radix Paeoniae Albas of 2 parts of Concha Margaritiferas of Radix Morindae Officinalis

1 part of 2 parts of Radix Bupleuri of 2 parts of Fructus Ligustri Lucidi of Herba Leonuri

1 part of 1 portion of Rhizoma Cyperi of 2 parts of Fructus Liquidambaris of Cortex Albiziae.

Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment climacteric syndrome that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1. a kind of Chinese medicine composition of treatment climacteric syndrome is characterized in that it is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 portions of Caulis Spatholobis of Radix Astragali

1.0～4 parts of 1.0～4 portions of Radix Paeoniae Albas of 1.0～4 parts of Concha Margaritiferas of Radix Morindae Officinalis

0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Fructus Ligustri Lucidi of Herba Leonuri

0.1～2 part of 0.1～2 portion of Rhizoma Cyperi of 1.0～4 parts of Fructus Liquidambaris of Cortex Albiziae.

2. a kind of Chinese medicine composition of treatment climacteric syndrome according to claim 1, wherein the weight proportion of each crude drug is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 portions of Caulis Spatholobis of Radix Astragali

1.5～2.5 parts of 1.5～2.5 portions of Radix Paeoniae Albas of 1.5～2.5 parts of Concha Margaritiferas of Radix Morindae Officinalis

0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Fructus Ligustri Lucidi of Herba Leonuri

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Cyperi of 1.5～2.5 parts of Fructus Liquidambaris of Cortex Albiziae.

3. a kind of Chinese medicine composition of treatment climacteric syndrome according to claim 1, wherein the weight proportion of each crude drug is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 portions of Caulis Spatholobis of Radix Astragali

2 parts of 2 portions of Radix Paeoniae Albas of 2 parts of Concha Margaritiferas of Radix Morindae Officinalis

1 part of 2 parts of Radix Bupleuri of 2 parts of Fructus Ligustri Lucidi of Herba Leonuri

1 part of 1 portion of Rhizoma Cyperi of 2 parts of Fructus Liquidambaris of Cortex Albiziae.