CN101095760A - Chinese traditional medicine composition for treating diabetes neurogenic bladder - Google Patents

Chinese traditional medicine composition for treating diabetes neurogenic bladder Download PDF

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Publication number
CN101095760A
CN101095760A CNA2007101183457A CN200710118345A CN101095760A CN 101095760 A CN101095760 A CN 101095760A CN A2007101183457 A CNA2007101183457 A CN A2007101183457A CN 200710118345 A CN200710118345 A CN 200710118345A CN 101095760 A CN101095760 A CN 101095760A
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parts
radix
chinese medicine
neurogenic bladder
medicine composition
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CNA2007101183457A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101183457A priority Critical patent/CN101095760A/en
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Abstract

The invention relates to a Chinese medicinal combination for treating diabetic neurogenic bladder which is prepared from more than ten kinds of Chinese medicinal herbs including broomrape, prepared rehmannia root, cyathula root and apricot seed. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

The Chinese medicine composition of treatment diabetic neurogenic bladder
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of diabetic neurogenic bladder, is that a kind of diabetic neurogenic bladder for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic neurogenic bladder is meant the maincenter of bladder or the urinary dysfunction that peripheral neuropathy causes, is called neurogenic bladder, is called cord bladder, nervous bladder functional disorder or atonic bladder again.The sickness rate of diabetic neurogenic bladder is 27%~85%.Because dysuria, easily cause the intractable urinary tract infection, increase the weight of diabetes so that influence renal function, be one of reason of diabetics death.According to the urine leaching glass not to the utmost, it is similar to " stranguria ", " difficulty in urination " in the Chinese medicine to urinate puckery symptom such as unfavorable.Pouring is meant that frequent micturition is short puckery, the sound of rain pattering not to the utmost, urethra is unfavorable, the cramp and pain in the lower abdomen person." Elementary Medicine ": " drench, whether difficulty and pain in micturition desired to go or not, and do not go to come again, drips constantly." can be divided into stranguria caused by urinary stone according to different performances clinically, qi stranguria, stranguria with blood, stranguria marked by chyluria, five kinds of strangurias caused by overstrain etc. are generically and collectively referred to as " five types of stranguria ".The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Herba Cistanches of 1.5~6 parts of Radix Rehmanniae Preparata of the Radix Astragali
1.0~4 parts of 1.0~4 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.0~4 portions of Radix Cyathulaes of Rhizoma Alismatis
0.1~2 part of 0.1~2 portion of Semen Plantaginis of 1.0~4 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Herba Cistanches of 2.5~3.5 parts of Radix Rehmanniae Preparata of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.5~2.5 portions of Radix Cyathulaes of Rhizoma Alismatis
0.5~1.5 part of 0.5~1.5 portion of Semen Plantaginis of 1.5~2.5 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Herba Cistanches of 3 parts of Radix Rehmanniae Preparata of the Radix Astragali
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 2 portions of Radix Cyathulaes of Rhizoma Alismatis
1 part of 1 portion of Semen Plantaginis of 2 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Herba Cistanches property of medicine is sweet, salty, temperature.Return kidney, large intestine channel.Has kidney-replenishing, benefiting essence-blood, the effect in intestine moistening road.Can treat the sexual impotence of kidney yang deficiency, asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, the lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation etc.(the 1226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Stir-baked SEMEN ARMENIACAE AMARUM property of medicine hardship, tepor, mild toxicity.Return lung, large intestine channel.Has lowering the adverse-rising QI to resolve phlegm, relieving cough and asthma, the effect of loosening bowel to relieve constipation.Can treat exogenous cough's dyspnea with fullness of the chest, dryness of the intestine constipation etc.(the 1526th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Aconiti Lateralis Preparata, Radix Rehmanniae Preparata, Herba Cistanches and the Radix Astragali; With Radix Cyathulae, Fructus Corni, Rhizoma Atractylodis Macrocephalae (parched), Rhizoma Alismatis and Pericarpium Citri Reticulatae is ministerial drug; With Cortex Cinnamomi, Semen Plantaginis and stir-baked SEMEN ARMENIACAE AMARUM is adjuvant.All medicines are harmonious, and are total to the tool warming YANG and invigorating QI, the effect of invigorating kidney to promote diuresis.The treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged;
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic neurogenic bladder of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic neurogenic bladder, and the prevention of diabetic neurogenic bladder is also had good effect, and the treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic neurogenic bladder; Treatment diabetic neurogenic bladder underwent 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 44.44%, and 7 examples that take a turn for the better account for 38.89%, and invalid 3 examples account for 16.67%, and total effective rate reaches 83.33%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Herba Cistanches of 3 parts of Radix Rehmanniae Preparata of the Radix Astragali
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 2 portions of Radix Cyathulaes of Rhizoma Alismatis
1 part of 1 portion of Semen Plantaginis of 2 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic neurogenic bladder that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine composition of treatment diabetic neurogenic bladder is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Herba Cistanches of 1.5~6 parts of Radix Rehmanniae Preparata of the Radix Astragali
1.0~4 parts of 1.0~4 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.0~4 portions of Radix Cyathulaes of Rhizoma Alismatis
0.1~2 part of 0.1~2 portion of Semen Plantaginis of 1.0~4 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
2, the Chinese medicine composition of treatment diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Herba Cistanches of 2.5~3.5 parts of Radix Rehmanniae Preparata of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.5~2.5 portions of Radix Cyathulaes of Rhizoma Alismatis
0.5~1.5 part of 0.5~1.5 portion of Semen Plantaginis of 1.5~2.5 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
3, the Chinese medicine composition of treatment diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Herba Cistanches of 3 parts of Radix Rehmanniae Preparata of the Radix Astragali
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 2 portions of Radix Cyathulaes of Rhizoma Alismatis
1 part of 1 portion of Semen Plantaginis of 2 parts of Fructus Corni of Pericarpium Citri Reticulatae
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of stir-baked SEMEN ARMENIACAE AMARUM of Cortex Cinnamomi.
CNA2007101183457A 2007-07-05 2007-07-05 Chinese traditional medicine composition for treating diabetes neurogenic bladder Pending CN101095760A (en)

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CNA2007101183457A CN101095760A (en) 2007-07-05 2007-07-05 Chinese traditional medicine composition for treating diabetes neurogenic bladder

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007229A (en) * 2012-12-27 2013-04-03 陈淑香 Medicine for treating neurogenic bladder
CN104940721A (en) * 2015-06-15 2015-09-30 哈尔滨医科大学附属第四医院 Traditional Chinese medicinal compound composition for treating neurogenic bladder disorders, preparation method and application thereof
CN104971211A (en) * 2014-04-02 2015-10-14 王嘉影 Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007229A (en) * 2012-12-27 2013-04-03 陈淑香 Medicine for treating neurogenic bladder
CN103007229B (en) * 2012-12-27 2013-11-27 陈淑香 Medicine for treating neurogenic bladder
CN104971211A (en) * 2014-04-02 2015-10-14 王嘉影 Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease
CN104940721A (en) * 2015-06-15 2015-09-30 哈尔滨医科大学附属第四医院 Traditional Chinese medicinal compound composition for treating neurogenic bladder disorders, preparation method and application thereof
CN104940721B (en) * 2015-06-15 2018-11-16 哈尔滨医科大学附属第四医院 A kind of Traditional Chinese medicine compound composition and the preparation method and application thereof with treatment neurogenic bladder disease

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