CN101112456A - Chinese traditional medicine preparation for treating habitual abortion - Google Patents

Chinese traditional medicine preparation for treating habitual abortion Download PDF

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Publication number
CN101112456A
CN101112456A CNA2007101209029A CN200710120902A CN101112456A CN 101112456 A CN101112456 A CN 101112456A CN A2007101209029 A CNA2007101209029 A CN A2007101209029A CN 200710120902 A CN200710120902 A CN 200710120902A CN 101112456 A CN101112456 A CN 101112456A
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China
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parts
radix
chinese medicine
habitual abortion
traditional chinese
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CNA2007101209029A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101209029A priority Critical patent/CN101112456A/en
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Abstract

The present invention relates to a traditional Chinese medicine preparation for treating habitual abortion, which takes more than 10 Chinese herbal medicines of cornu cervi degelatinatum, barbary wolfberry fruit, south dodder seed and astragalus etc. as the raw materials. The present invention has the effects of tonifying the spleen and the kidney, benefiting qi and securing fetus. The present invention is developed based on the differential treatment of the traditional Chinese medicine, which is also combined with the latest scientific research results. The present invention aims at providing the traditional Chinese medicine preparation to treat habitual abortion. The present invention is characterized by accurate efficacy, safety, reliability, no toxicity or side effects and low price.

Description

A kind of Chinese medicine preparation for the treatment of habitual abortion
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of habitual abortion, is that a kind of habitual abortion for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Miscarriage is meant that the clinical manifestation of miscarriage is vaginal hemorrhage and the different stomachache of degree after the menolipsis gestation before 28 weeks, the not enough 1000g of fetal weight and termination person.Miscarriage is human reproduction's natural selection, account for 75% of germ cell, wherein only about 15% because of have the miscarriage symptom by clinical understanding, remaining then often shows as dysfunctional uterine bleeding, delayed period etc., germ cell in early days promptly by natural selection and not known, this is a kind of phenomenon of screening naturally that produces offspring, and miscarriage has play a part certain to option of species really.The cardinal symptom and the residing different phase thereof that are showed in the process according to miscarriage are divided into threatened abortion, habitual abortion, inevitable abortion, incomplete abortion, artificial abortion and missed abortion.The category such as " vaginal bleeding during pregnancy ", " frequent fetal movement ", " abdominal pain during pregnancy ", " habitual abortion ", " induced abortion ", " abortion ", " abortion within the first month of pregnancy ", " inevitable abortion ", " retention of dead fetus " that belongs to Chinese medicine respectively.The spontaneous abortion that is meant habitual abortion recurs person more than 3 times or 3 times.Pregnant repeatly falling repeatly must be hindered towards appointing, so deficiency syndrome are seen more." deficiency syndrome should be treated by tonifying method " is that mainly executing of habitual abortion disease controlled principle.And should grasp the measure of " putting prevention first and combining prevention with control ".Before unpregnancy, answer kidney and spleen invigorating, benefiting QI and nourishing blood, it is main transferring Gu Chong to appoint.The pregnant treatment of promptly should preventing miscarriage afterwards.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of kidney-QI, deficient qi and blood, deficiency of YIN heat in blood, blood-stasis internal-depression clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of habitual abortion.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.0~4 parts of 1.0~4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5~6 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
0.1~2 part of 1.0~4 parts of Radix Codonopsis of 1.5~6 parts of Fructus Lycii of Fructus Psoraleae
0.1~2 part of 1.0~4 parts of Radix Dipsaci of 1.5~6 parts of Radix Rehmanniae Preparata of Radix Astragali
0.1~2 part of 1.0~4 parts of Radix Angelicae Sinensis of 1.0~4 parts of Semen Cuscutae of Radix Morindae Officinalis.
The weight proportion of each crude drug of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5~3.5 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
0.5~1.5 part of 1.5~2.5 parts of Radix Codonopsis of 2.5~3.5 parts of Fructus Lycii of Fructus Psoraleae
0.5~1.5 part of 1.5~2.5 parts of Radix Dipsaci of 2.5~3.5 parts of Radix Rehmanniae Preparata of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Radix Angelicae Sinensis of 1.5~2.5 parts of Semen Cuscutae of Radix Morindae Officinalis.
The weight proportion of each crude drug of optimum formula of the present invention is:
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
1 part of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Fructus Psoraleae
1 part of 2 parts of Radix Dipsaci of 3 parts of Radix Rehmanniae Preparata of Radix Astragali
1 part of 2 parts of Radix Angelicae Sinensis of 2 parts of Semen Cuscutae of Radix Morindae Officinalis.
Drug action mechanism among the present invention is as follows:
The Cornu Cervi Degelatinatum property of medicine is salty, puckery, temperature.Return kidney, Liver Channel.Has reinforcing the kidney and supporting YANG, anastaltic effect.Can treat emission due to deficiency of the kidney, night sweat, anorexia and loose stool, chronic diarrhea chronic dysentery, metrorrhagia, leukorrhagia, frequent micturition, the enuresis, dribble of urine, skin infection disunion of a specified duration, wound hemorrhage etc.(the 3118th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Psoraleae property of medicine suffering, hardship, temperature.Return kidney, spleen channel.Has reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal effect.Can treat the deficiency and coldness lumbago, sexual impotence spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, dyspnea due to deficiency, vitiligo, alopecia areata, psoriasis etc.(the 1647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Dipsaci property of medicine hardship, suffering, tepor.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, the effect of ending metrorrhagia.Can treat aching pain in waist and back, the podomere flaccidity syndrome and arthralgia syndrome falls and pounces on wound, decreases muscle folding bone, and fetal movement is leaked red, metrorrhagia, and seminal emission, leukorrhagia, the carbuncle skin ulcer is swollen etc.(the 3172nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cornu Cervi Degelatinatum, Fructus Psoraleae and Radix Astragali; With Radix Morindae Officinalis, the Cortex Eucommiae, Fructus Lycii, Radix Rehmanniae Preparata, Semen Cuscutae and the Rhizoma Atractylodis Macrocephalae is ministerial drug; With Radix Codonopsis, Radix Dipsaci with when being classified as adjuvant.All medicines are harmonious, and are total to the tool kidney and spleen invigorating, the effect of the solid tire of QI invigorating.The treatment habitual abortion has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment habitual abortion of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat habitual abortion, and the prevention of habitual abortion is also had good effect, and the treatment habitual abortion has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment habitual abortion; Treatment habitual abortion patients 28 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.14 examples of fully recovering account for 50%, and 11 examples that take a turn for the better account for 39.29%, and invalid 3 examples account for 10.71%, and total effective rate reaches 89.29%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
1 part of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Fructus Psoraleae
1 part of 2 parts of Radix Dipsaci of 3 parts of Radix Rehmanniae Preparata of Radix Astragali
1 part of 2 parts of Radix Angelicae Sinensis of 2 parts of Semen Cuscutae of Radix Morindae Officinalis.
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment habitual abortion that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of habitual abortion is characterized in that it is made by following raw materials by weight proportions:
1.0~4 parts of 1.0~4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5~6 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
0.1~2 part of 1.0~4 parts of Radix Codonopsis of 1.5~6 parts of Fructus Lycii of Fructus Psoraleae
0.1~2 part of 1.0~4 parts of Radix Dipsaci of 1.5~6 parts of Radix Rehmanniae Preparata of Radix Astragali
0.1~2 part of 1.0~4 parts of Radix Angelicae Sinensis of 1.0~4 parts of Semen Cuscutae of Radix Morindae Officinalis.
2. a kind of Chinese medicine preparation for the treatment of habitual abortion according to claim 1, wherein the weight proportion of each crude drug is:
1.5~2.5 parts of 1.5~2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5~3.5 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
0.5~1.5 part of 1.5~2.5 parts of Radix Codonopsis of 2.5~3.5 parts of Fructus Lycii of Fructus Psoraleae
0.5~1.5 part of 1.5~2.5 parts of Radix Dipsaci of 2.5~3.5 parts of Radix Rehmanniae Preparata of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Radix Angelicae Sinensis of 1.5~2.5 parts of Semen Cuscutae of Radix Morindae Officinalis.
3. a kind of Chinese medicine preparation for the treatment of habitual abortion according to claim 1, wherein the weight proportion of each crude drug is:
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Cortexs Eucommiae of Cornu Cervi Degelatinatum
1 part of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Fructus Psoraleae
1 part of 2 parts of Radix Dipsaci of 3 parts of Radix Rehmanniae Preparata of Radix Astragali
1 part of 2 parts of Radix Angelicae Sinensis of 2 parts of Semen Cuscutae of Radix Morindae Officinalis.
CNA2007101209029A 2007-08-29 2007-08-29 Chinese traditional medicine preparation for treating habitual abortion Pending CN101112456A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166317A (en) * 2011-04-22 2011-08-31 南阳理工学院 Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis
CN103071105A (en) * 2013-02-06 2013-05-01 孙迎春 External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof
CN105663443A (en) * 2016-03-04 2016-06-15 陈红 Pharmaceutical composition for treating kidney deficiency and blood heat type recurrent abortion
CN105748717A (en) * 2016-03-04 2016-07-13 陈红 Pharmaceutical composition for treating renal deficiency and blood stasis type recurrent spontaneous abortion
CN105770291A (en) * 2016-03-21 2016-07-20 徐美英 Medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies
CN108210650A (en) * 2016-12-17 2018-06-29 景金发 Donkey-hide gelatin QI invigorating preparation
CN109432263A (en) * 2018-12-10 2019-03-08 张云鹤 A kind of prescription for treating habitual abortion

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166317A (en) * 2011-04-22 2011-08-31 南阳理工学院 Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis
CN102166317B (en) * 2011-04-22 2012-06-27 南阳理工学院 Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis
CN103071105A (en) * 2013-02-06 2013-05-01 孙迎春 External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof
CN103071105B (en) * 2013-02-06 2014-09-03 孙迎春 External traditional Chinese medicinal preparation for treating threatened abortion and preparation method thereof
CN105663443A (en) * 2016-03-04 2016-06-15 陈红 Pharmaceutical composition for treating kidney deficiency and blood heat type recurrent abortion
CN105748717A (en) * 2016-03-04 2016-07-13 陈红 Pharmaceutical composition for treating renal deficiency and blood stasis type recurrent spontaneous abortion
CN105770291A (en) * 2016-03-21 2016-07-20 徐美英 Medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies
CN108210650A (en) * 2016-12-17 2018-06-29 景金发 Donkey-hide gelatin QI invigorating preparation
CN109432263A (en) * 2018-12-10 2019-03-08 张云鹤 A kind of prescription for treating habitual abortion

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