CN101053613A - Traditional Chinese medicine preparations for treating luteal phase defect sterility - Google Patents
Traditional Chinese medicine preparations for treating luteal phase defect sterility Download PDFInfo
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- CN101053613A CN101053613A CNA2007100992257A CN200710099225A CN101053613A CN 101053613 A CN101053613 A CN 101053613A CN A2007100992257 A CNA2007100992257 A CN A2007100992257A CN 200710099225 A CN200710099225 A CN 200710099225A CN 101053613 A CN101053613 A CN 101053613A
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Abstract
The invention relates to a Chinese medicinal preparation for treating sterility caused by corpus luteum insufficiency consisting of dozens of Chinese medicinals including dodder, raw milkvetch root, epimedium, prepared rehmannia root etc. The invention combines syndrome differentiation in TCM and latest study result of western medicine. It has confirmed efficacy, being safe, convenient and cheap, besides no side or toxic effect will be caused.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of luteal phase deficiency infertility, is that a kind of luteal phase deficiency infertility for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Luteal phase defect is that corpus luteum divides secret progesterone deficiency or corpus luteum to fail too early, so that the endometrial secretion poor response, is an impediment to implantation of ovum.Have approximately in the infertile patient in 3%～10% the habitual early abortion and have 35%～67%, caused by luteal phase defect.The traditional Chinese medical science thinks that primary disease mainly is owing to plain body weakness, and deficiency of kidney-QI dashes and appoints void to decline, and therefore can not become pregnant by consolidating semen.Also damage kidney qi because of a little less than the deficiency of kidney-QI or pregnant back even become pregnant, suffering from a deficiency of the kidney unable is tire so that miscarriage.Wherein with insufficiency of kidney-YANG for seeing more, insufficiency of kidney-YANG then can not warm uterus, then causes infertility.Its pathogenic factor is that the The Long-term Effect of air-cooled or cold-damp, congenital kidney qi owe to contain, the exhaustion due to sexual indulgence fecund, emotional instability, daily life impermanence, after the serious disease prolonged illness, overwork, drink cold too much etc., make deficiency of kidney-YIN, the last of the ten Heavenly stems water deficiency, smart ovum is immature, can not be converted into sun, show as cloudy deficiency of YANG of middle-JIAO, a little less than the water moderate heat, luteal function is unsound.YANG QI deficiency, the spleen kidney is inevitable not enough.If the disposition depression, feelings are not smooth, or the irritability of being enraged, or too much worried, cause the conscience stagnation of QI, and functional activity of QI being not smooth is dashed appoint and supported mutually, and inclined to one side in addition insufficiency of kidney-YANG is suffered from a deficiency of the kidney stagnation of liver-QI and caused infertile.Plain body depression, the strongly fragrant one-tenth stasis of blood of a specified duration, or the surplus stasis of blood of multiparity is unclean, or have sexual intercourse menstrual period, stasis of blood essential resistance of turbid, the yang deficiency blood stasis can not become pregnant.If body is reported yang deficiency, the spleen kidney is not enough to some extent, throws off restraint the food rich and fatty diet, or overnutrition, is disinclined to action, and it is on the high side sleep, Lack of Movement, and fate is too late, and phlegm-damp fat is turbid to be accumulate and hinders among the born of the same parents and cause infertile.The traditional Chinese medical science is divided into kidney yang clinically and loses void, and the disease type Coryza Treated by Syndrome Differentiation such as stagnation of liver-QI of suffering from a deficiency of the kidney obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of luteal phase deficiency infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Dipsacis of 1.5～6 parts of Radix Rehmanniae Preparata of Semen Cuscutae
1.0～4 parts of 1.0～4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 parts of Radix Morindae Officinaliss of Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.5～6 parts of Fructus Lycii of Herba Epimedii
1.0～4 parts of 0.1～2 part of Radix Codonopsis of 0.1～2 part of Cortex Eucommiae of Colla Cornus Cervi
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Dipsacis of 2.5～3.5 parts of Radix Rehmanniae Preparata of Semen Cuscutae
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 parts of Radix Morindae Officinaliss of Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 2.5～3.5 parts of Fructus Lycii of Herba Epimedii
1.5～2.5 parts of 0.5～1.5 part of Radix Codonopsis of 0.5～1.5 part of Cortex Eucommiae of Colla Cornus Cervi
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Radix Dipsacis of 3 parts of Radix Rehmanniae Preparata of Semen Cuscutae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Morindae Officinaliss of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 3 parts of Fructus Lycii of Herba Epimedii
2 parts of 1 part of Radix Codonopsis of 1 part of Cortex Eucommiae of Colla Cornus Cervi
Drug action mechanism among the present invention is as follows:
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Dipsaci property of medicine hardship, suffering, tepor.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, the effect of ending metrorrhagia.Can treat aching pain in waist and back, the podomere flaccidity syndrome and arthralgia syndrome falls and pounces on wound, decreases muscle folding bone, and fetal movement is leaked red, metrorrhagia, and seminal emission, leukorrhagia, the carbuncle skin ulcer is swollen etc.(the 3172nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Colla Cornus Cervi property of medicine is salty, temperature.Return kidney, Liver Channel.Have the kidney warming, benefit is smart, bone and muscle strengthening, promoting the circulation of blood repercussive effect.Can treat the spinal column cold type of pain, sexual impotence, seminal emission, metrorrhagia, leukorrhagia, frequent micturition, carbuncle of yin nature skin infection, acute mastitis, traumatic injury congestive edema, bones and muscles pain etc.(the 3105th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Cuscutae, Radix Astragali and Herba Epimedii; With Radix Rehmanniae Preparata, Radix Morindae Officinalis, Fructus Lycii, Radix Dipsaci, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and Radix Codonopsis is ministerial drug; With the Colla Cornus Cervi and the Cortex Eucommiae is adjuvant.All medicines are harmonious, altogether the effect of tool kidney warming and yang invigorating.The treatment luteal phase deficiency infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment luteal phase deficiency infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat luteal phase deficiency infertility, prevention to luteal phase deficiency infertility also has good effect, and the treatment luteal phase deficiency infertility has determined curative effect, has no side effect, taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment luteal phase deficiency infertility; Treatment luteal phase deficiency infertility patient 47 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.34 examples of fully recovering account for 77.19%, and 9 examples that take a turn for the better account for 15.79%, and more 4 examples do not account for 7%, and total effective rate reaches 93%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Radix Dipsacis of 3 parts of Radix Rehmanniae Preparata of Semen Cuscutae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Morindae Officinaliss of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 3 parts of Fructus Lycii of Herba Epimedii
2 parts of 1 part of Radix Codonopsis of 1 part of Cortex Eucommiae of Colla Cornus Cervi
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment luteal phase deficiency infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of luteal phase deficiency infertility is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Dipsacis of 1.5～6 parts of Radix Rehmanniae Preparata of Semen Cuscutae
1.0～4 parts of 1.0～4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 parts of Radix Morindae Officinaliss of Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.5～6 parts of Fructus Lycii of Herba Epimedii
1.0～4 parts of 0.1～2 part of Radix Codonopsis of 0.1～2 part of Cortex Eucommiae of Colla Cornus Cervi.
2, a kind of Chinese medicine preparation for the treatment of luteal phase deficiency infertility according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Dipsacis of 2.5～3.5 parts of Radix Rehmanniae Preparata of Semen Cuscutae
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 parts of Radix Morindae Officinaliss of Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 2.5～3.5 parts of Fructus Lycii of Herba Epimedii
1.5～2.5 parts of 0.5～1.5 part of Radix Codonopsis of 0.5～1.5 part of Cortex Eucommiae of Colla Cornus Cervi.
3, a kind of Chinese medicine preparation for the treatment of luteal phase deficiency infertility according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Radix Dipsacis of 3 parts of Radix Rehmanniae Preparata of Semen Cuscutae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 parts of Radix Morindae Officinaliss of Radix Astragali
2 parts of 2 parts of Radix Angelicae Sinensis of 3 parts of Fructus Lycii of Herba Epimedii
2 parts of 1 part of Radix Codonopsis of 1 part of Cortex Eucommiae of Colla Cornus Cervi.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100992257A CN101053613A (en) | 2007-05-16 | 2007-05-16 | Traditional Chinese medicine preparations for treating luteal phase defect sterility |
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| CNA2007100992257A CN101053613A (en) | 2007-05-16 | 2007-05-16 | Traditional Chinese medicine preparations for treating luteal phase defect sterility |
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| CN101053613A true CN101053613A (en) | 2007-10-17 |
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| CNA2007100992257A Pending CN101053613A (en) | 2007-05-16 | 2007-05-16 | Traditional Chinese medicine preparations for treating luteal phase defect sterility |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018795A (en) * | 2010-12-24 | 2011-04-20 | 武汉大学 | Traditional Chinese medicine composition for improving endometrial receptivity |
| CN103735981A (en) * | 2013-12-11 | 2014-04-23 | 山东中大药业有限公司 | Kidney-tonifying pregnancy-promoting traditional Chinese medicine formula and preparation method |
| CN104352776A (en) * | 2014-12-09 | 2015-02-18 | 徐姝一 | Traditional Chinese medicine preparation for treating infertility caused by hypomenorrhea and preparation method thereof |
-
2007
- 2007-05-16 CN CNA2007100992257A patent/CN101053613A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018795A (en) * | 2010-12-24 | 2011-04-20 | 武汉大学 | Traditional Chinese medicine composition for improving endometrial receptivity |
| CN102018795B (en) * | 2010-12-24 | 2011-12-28 | 武汉大学 | Traditional Chinese medicine composition for improving endometrial receptivity |
| CN103735981A (en) * | 2013-12-11 | 2014-04-23 | 山东中大药业有限公司 | Kidney-tonifying pregnancy-promoting traditional Chinese medicine formula and preparation method |
| CN104352776A (en) * | 2014-12-09 | 2015-02-18 | 徐姝一 | Traditional Chinese medicine preparation for treating infertility caused by hypomenorrhea and preparation method thereof |
| CN104352776B (en) * | 2014-12-09 | 2017-11-21 | 徐姝一 | A kind of hypomenorrhia for the treatment of causes infertile Chinese medicine preparation and preparation method thereof |
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Open date: 20071017 |