CN101085253A - Traditional Chinese medicine composition for treating nephrotic syndrome - Google Patents
Traditional Chinese medicine composition for treating nephrotic syndrome Download PDFInfo
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- CN101085253A CN101085253A CN 200710117894 CN200710117894A CN101085253A CN 101085253 A CN101085253 A CN 101085253A CN 200710117894 CN200710117894 CN 200710117894 CN 200710117894 A CN200710117894 A CN 200710117894A CN 101085253 A CN101085253 A CN 101085253A
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Abstract
The invention relates to a Chinese medicinal combination for treating nephrotic syndrome which is prepared from more than ten kinds of Chinese medicinal herbs including white atractylodes rhizome, raw astragalus root, red phaseolus bean and corn stigma.
Description
Technical field
The present invention relates to treat the Chinese medicine composition of nephrotic syndrome, is that a kind of nephrotic syndrome for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
(Nephrotic Syndrome NS) is proposed in 1932 by foreign scholar Hriction nephrotic syndrome.In order to summarize one group of card Hou Qun in the renal glomerular disease, it accounts for 70%～90% in child's renal glomerular disease, also account for 20%～30% in the adult.All have clinically a large amount of albuminuria (every day＞3.5g), hypoproteinemia (albumin＜30g/L), obviously edema, hyperlipemia (characteristic person such as serum cholesterol＞6.5mmol/L) can examine and is nephrotic syndrome.Nephrotic syndrome is at the clinical branch that constitutional and Secondary cases are arranged.Primary nephrotic syndrome (PNS) refers to by the sick causer of primary glomerular, adult's the most nephrotic syndrome of 2/3 and child is constitutional, pathological change is mainly the minute lesion type, and part is changes such as film, proliferative, film proliferative and focal nephrosclerosis.The patient of morbidity more than 45 years old, may be except must noting with malignant tumor, with Hodgkin, membranous nephropathy accompanies by solid tumors such as lung, breast, gastrointestinal etc. as minimal change nephropathy.The Secondary cases nephrotic syndrome is meant and is secondary to the whole body other diseases or by specificity cause of disease causer, as medicine mediation property nephrotic syndrome, the nephrotic syndrome that causes by allergy, poisoning, immunoreation, the nephrotic syndrome that causes by infection such as antibacterial, virus, parasites, nephrotic syndrome due to tumor and the heredity, nephrotic syndrome that metabolic disease caused such as systemic disease such as connective tissue, anaphylactoid purpura and diabetes, amyloidosis etc.Nephrotic syndrome 1/3 and the child 10% who is grown up can be by above-mentioned cause of disease secondary.Disease categories such as " edema " of nephrotic syndrome ownership Chinese medicine, " asthenia ".The clinical manifestation of primary disease is: a large amount of albuminuria (＞3.5g/24h), hypoproteinemia (albumin＜30g/L), obviously edema, hyperlipemia.
The nephrotic syndrome course of disease is long, the relapse rate height, and simple western medicine treatment often can not obtain ideal effect, some intractable nephrotic syndromes especially, clinical treatment is often more thorny.And adopt the comprehensive method treatment nephrotic syndrome of Chinese and western medicine, and not only enlarged the treatment approach, and clinical confirmation obtained gratifying curative effect, be considered to comparatively ideal therapeutic scheme.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as retention of damp-heat in the interior, the wet dipping of water, edema due to YANG-insufficiency, stagnation of dampness due to deficiency of the spleen, edema due to wind pathogen Xiang Bo clinically, obtains very good effect.Therefore invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine composition for the treatment of nephrotic syndrome.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts in 1.0～4 parts of Poria of 1.5～6 portions of Radix Cyathulaes of Semen Phaseoli
1.0～4 parts of 1.0～4 portions of Polyporus of 1.5～6 parts of Stigma Maydis of Radix Astragali
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.5～6 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
0.1～2 part of 0.1～2 portion of Cortex Cinnamomi of 0.1～2 part of Pericarpium Arecae of Semen Plantaginis.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts in 1.5～2.5 parts of Poria of 2.5～3.5 portions of Radix Cyathulaes of Semen Phaseoli
1.5～2.5 parts of 1.5～2.5 portions of Polyporus of 2.5～3.5 parts of Stigma Maydis of Radix Astragali
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
0.5～1.5 part of 0.5～1.5 portion of Cortex Cinnamomi of 0.5～1.5 part of Pericarpium Arecae of Semen Plantaginis.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts in 2 parts of Poria of 3 portions of Radix Cyathulaes of Semen Phaseoli
2 parts of 2 portions of Polyporus of 3 parts of Stigma Maydis of Radix Astragali
2 parts of 2 portions of Rhizoma Alismatis of 3 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
1 part of 1 portion of Cortex Cinnamomi of 1 part of Pericarpium Arecae of Semen Plantaginis.
Drug action mechanism among the present invention is as follows:
The Semen Phaseoli property of medicine is sweet, sour, is slightly cold.GUIXIN, small intestinal, spleen channel.Has the inducing diuresis to remove edema jaundice eliminating, the effect of heat-clearing and toxic substances removing eliminating carbuncle.Can treat edema, beriberi, jaundice, gonorrhea is had blood in stool, toxic swelling skin infection, scall etc.(the 1443rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Stigma Maydis property of medicine is sweet, light, and is flat.Return kidney, stomach, liver, gallbladder meridian.Has inducing diuresis to remove edema, the effect of liver heat removing function of gallbladder promoting.Can treat edema, stranguria, nebulousurine is quenched one's thirst, jaundice, cholecystitis, cholelithiasis, hypertension, acute mastitis, galactostasis etc.(the 777th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Polyporus property of medicine is sweet, light, and is flat.Return spleen, kidney, urinary bladder channel.Effect with promoting diuresis to eliminate damp pathogen.Can treat dysuria, the edema distension is had loose bowels, stranguria with turbid discharge, leukorrhagia, beriberi edema etc.(the 3060th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Arecae property of medicine suffering, tepor.Return spleen, stomach, large intestine, small intestine meridian.Has therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the effect of line water detumescence.It is vexed to treat breast abdominal distention, edema, beriberi, dysuria etc.(the 178th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched) and Semen Phaseoli; With Poria, Polyporus, Cortex Cinnamomi, Radix Cyathulae, Stigma Maydis, Rhizoma Alismatis and Herba Leonuri is ministerial drug; With Semen Plantaginis and Pericarpium Arecae is adjuvant.All medicines are harmonious, and are total to the tool replenishing QI to invigorate the spleen, the effect of warming YANG to promote diuresis.The treatment nephrotic syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment nephrotic syndrome of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat nephrotic syndrome, and the prevention of nephrotic syndrome is also had good effect, and the treatment nephrotic syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treatment management of Idiopathic Nephrotic Syndrome in Children effect; Treatment nephrotic syndrome patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 40%, and 12 examples that take a turn for the better account for 48%, and invalid 3 examples account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts in 2 parts of Poria of 3 portions of Radix Cyathulaes of Radix Astragali
2 parts of 2 portions of Polyporus of 3 parts of Stigma Maydis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 portions of Rhizoma Alismatis of 3 parts of Herba Leonuris of Semen Phaseoli
1 part of 1 portion of Cortex Cinnamomi of 1 part of Pericarpium Arecae of Semen Plantaginis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment nephrotic syndrome that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, the Chinese medicine composition of treatment nephrotic syndrome is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts in 1.0～4 parts of Poria of 1.5～6 portions of Radix Cyathulaes of Semen Phaseoli
1.0～4 parts of 1.0～4 portions of Polyporus of 1.5～6 parts of Stigma Maydis of Radix Astragali
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.5～6 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
0.1～2 part of 0.1～2 portion of Cortex Cinnamomi of 0.1～2 part of Pericarpium Arecae of Semen Plantaginis.
2, the Chinese medicine composition of treatment nephrotic syndrome according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts in 1.5～2.5 parts of Poria of 2.5～3.5 portions of Radix Cyathulaes of Semen Phaseoli
1.5～2.5 parts of 1.5～2.5 portions of Polyporus of 2.5～3.5 parts of Stigma Maydis of Radix Astragali
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
0.5～1.5 part of 0.5～1.5 portion of Cortex Cinnamomi of 0.5～1.5 part of Pericarpium Arecae of Semen Plantaginis.
3, the Chinese medicine composition of treatment nephrotic syndrome according to claim 1, wherein the weight proportion of each raw material is:
2 parts in 2 parts of Poria of 3 portions of Radix Cyathulaes of Semen Phaseoli
2 parts of 2 portions of Polyporus of 3 parts of Stigma Maydis of Radix Astragali
2 parts of 2 portions of Rhizoma Alismatis of 3 parts of Herba Leonuris of Rhizoma Atractylodis Macrocephalae (parched)
1 part of 1 portion of Cortex Cinnamomi of 1 part of Pericarpium Arecae of Semen Plantaginis.
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| CN 200710117894 CN101085253A (en) | 2007-06-26 | 2007-06-26 | Traditional Chinese medicine composition for treating nephrotic syndrome |
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| CN 200710117894 CN101085253A (en) | 2007-06-26 | 2007-06-26 | Traditional Chinese medicine composition for treating nephrotic syndrome |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810796A (en) * | 2010-04-22 | 2010-08-25 | 吴贵成 | Medicament for treating nephritic syndromes |
| CN103028056A (en) * | 2012-12-04 | 2013-04-10 | 肖毅峰 | Frequently-drank tea-substituting traditional Chinese medicine preparation for treating kidney diseases |
| CN104258320A (en) * | 2014-09-11 | 2015-01-07 | 湖北省中医院 | Traditional Chinese medicine preparation for treating hypertensive renal injury edema and preparation method of traditional Chinese medicine preparation |
| CN105288273A (en) * | 2015-10-29 | 2016-02-03 | 李连庆 | Formula for treating nephrotic syndrome and preparation method |
| CN105327163A (en) * | 2015-10-29 | 2016-02-17 | 李连庆 | Preparation used for treating nephrotic syndromes and achieving dampness resolving and detumescence and preparation method |
| CN106266641A (en) * | 2015-05-11 | 2017-01-04 | 杜乃龙 | A kind of formula controlling the nephrotic syndrome |
-
2007
- 2007-06-26 CN CN 200710117894 patent/CN101085253A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810796A (en) * | 2010-04-22 | 2010-08-25 | 吴贵成 | Medicament for treating nephritic syndromes |
| CN101810796B (en) * | 2010-04-22 | 2011-06-22 | 吴贵成 | Medicament for treating nephritic syndromes |
| CN103028056A (en) * | 2012-12-04 | 2013-04-10 | 肖毅峰 | Frequently-drank tea-substituting traditional Chinese medicine preparation for treating kidney diseases |
| CN104258320A (en) * | 2014-09-11 | 2015-01-07 | 湖北省中医院 | Traditional Chinese medicine preparation for treating hypertensive renal injury edema and preparation method of traditional Chinese medicine preparation |
| CN104258320B (en) * | 2014-09-11 | 2016-01-20 | 湖北省中医院 | A kind ofly treat Chinese medicine preparation of hypertensive renal damage edema and preparation method thereof |
| CN106266641A (en) * | 2015-05-11 | 2017-01-04 | 杜乃龙 | A kind of formula controlling the nephrotic syndrome |
| CN105288273A (en) * | 2015-10-29 | 2016-02-03 | 李连庆 | Formula for treating nephrotic syndrome and preparation method |
| CN105327163A (en) * | 2015-10-29 | 2016-02-17 | 李连庆 | Preparation used for treating nephrotic syndromes and achieving dampness resolving and detumescence and preparation method |
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Open date: 20071212 |