CN101249257A - Traditional Chinese medicine preparation for curing edematous - Google Patents

Traditional Chinese medicine preparation for curing edematous Download PDF

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Publication number
CN101249257A
CN101249257A CNA2008101037169A CN200810103716A CN101249257A CN 101249257 A CN101249257 A CN 101249257A CN A2008101037169 A CNA2008101037169 A CN A2008101037169A CN 200810103716 A CN200810103716 A CN 200810103716A CN 101249257 A CN101249257 A CN 101249257A
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China
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parts
chinese medicine
edema
traditional chinese
medicine preparation
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CNA2008101037169A
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Chinese (zh)
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王信锁
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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Priority to CNA2008101037169A priority Critical patent/CN101249257A/en
Publication of CN101249257A publication Critical patent/CN101249257A/en
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Abstract

The invention relates to a traditional Chinese medicine preparation used to cure edema. The traditional Chinese medicine takes more than 10 species of Chinese herb medicines as the raw materials, such as plaster stone, white mulberry root-bark, waxgourd peel, fried atractylodes macrocephala koidz, etc., and has the efficacies of benefiting qi and strengthening superficies as well as inducing diuresis to alleviate edema. The invention is formed by combining the latest achievements in scientific research with the basis of traditional Chinese medicine syndrome differentiation and treatment. The invention aims to provide the traditional Chinese medicine preparation used to cure the edema. The traditional Chinese medicine preparation used to cure the edema has the advantages of obvious curative effect, convenient and safe usage, no side effects and low cost.

Description

A kind of Chinese medicine preparation for the treatment of edema
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of edema, is that a kind of edema for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Edema is dirty to the defeated cloth functional disorder in water liquid Xuanhua by lung spleen kidney three, causes the interior water humidity hysteresis of body and stays, and spreads unchecked skin, causes a kind of disease of women's head-ornaments, extremity, abdominal part even anasarca.Be more common in acute and chronic glomerulonephritis, nephrotic syndrome, congestive heart failure, the secret imbalance of interior branch, and disease such as malnutrition.The major lesions of edema is at kidney, but the internal organs that relate to are more, and its pathogenesis has exopathogen invasion and attack, the not normal or overstrain internal injury of daily life.Main pathogenesis is that lung loses logical the accent, and spleen loses and transfers, and kidney loses folding, and functioning of bladder is had no right, and the three warmers water channel loses smooth, and water liquid stops gathering, and spreads unchecked skin.Lung spleen kidney three dirty connecting each other influence each other, and wherein are this with the kidney, are mark with the lung, are the dirty of controlling the water circulation with the spleen.When dialectical, be guiding principle with negative and positive, allly experience ailment said due to cold or exposure, aqueous vapor, noxious dampness, damp and hot all heresies, card sees Table, heat, excess syndrome person, how to control by the YANG edema opinion; All excess of sexual intercourse, improper diet and overtiredness, how damage healthy energy in card is seen, empty, cold syndrome person, is controlled from the YIN edema opinion.YANG edema, YIN edema can transform mutually.In the treatment, YANG edema person is based on eliminating evil, how with diaphoresis, diuresis, attack method such as pursue; YIN edema person then gives strengthening vital QI to eliminate pathogenic factors, and the person of setting upright has methods such as spleen invigorating, the kidney warming; The well-established law treatment is not answered as warp, or blood stasis sign person is arranged, and can join and use activating blood and removing stasis Method.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as the rich mutually card in edema due to wind pathogen, the wet dipping of water card, retention of damp-heat in the interior card, syndrome of dampness stagnancy due to spleen deficiency, syndrome of water over-flowing due to YANG-insufficiency clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of edema.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.0~4 parts in 1.0~4 parts of Poria of 1.5~6 parts of Cortex Mori of Radix Astragali
0.1~2 part of 1.0~4 parts of Cortex Zingiberis of 1.5~6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
0.1~2 part in 1.0~4 portions of Radix Glycyrrhizaes of 1.5~6 parts of Cortex Lycii of Semen Phaseoli
0.3~1.2 part in 0.1~2 portion of Herba Ephedrae of 1.0~4 portions of Semen Plantaginiss of Gypsum Fibrosum.
The weight proportion of each crude drug of optimization formula of the present invention is:
1.5~2.5 parts in 1.5~2.5 parts of Poria of 2.5~3.5 parts of Cortex Mori of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Cortex Zingiberis of 2.5~3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
0.5~1.5 part in 1.5~2.5 portions of Radix Glycyrrhizaes of 2.5~3.5 parts of Cortex Lycii of Semen Phaseoli
0.4~0.8 part in 0.5~1.5 portion of Herba Ephedrae of 1.5~2.5 portions of Semen Plantaginiss of Gypsum Fibrosum.
The weight proportion of each crude drug of optimum formula of the present invention is:
2 parts in 2 parts of Poria of 3 parts of Cortex Mori of Radix Astragali
1 part of 2 parts of Cortex Zingiberis of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
1 part in 2 portions of Radix Glycyrrhizaes of 3 parts of Cortex Lycii of Semen Phaseoli
0.6 part in 1 portion of Herba Ephedrae of 2 portions of Semen Plantaginiss of Gypsum Fibrosum.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Exocarpium Benincasae nature and flavor are sweet, cold.Return spleen, small intestine meridian.Effect with inducing diuresis to remove edema.Can treat the edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine etc.(the 86th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Semen Phaseoli property of medicine is sweet, sour, is slightly cold.GUIXIN, small intestinal, spleen channel.Has the inducing diuresis to remove edema jaundice eliminating, the effect of heat-clearing and toxic substances removing eliminating carbuncle.Can treat edema, beriberi, jaundice, gonorrhea is had blood in stool, toxic swelling skin infection, scall etc.(the 1443rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Gypsum Fibrosum property of medicine suffering, sweet, cold.Return stomach, lung meridian.Has clearing away heat-fire, the effect that relieving restlessness is quenched the thirst.Can treat the calentura hyperpyrexia, excessive thirst, unconsciousness and delirium is gone mad, and sends out speckle, dyspnea and cough due to lung-heat, heatstroke, stomach-fire headache, toothache, aphtha of the mouth and tongue.Forge then promoting tissue regeneration and ulcer healing, control ulcer sores and burst and not close up burn etc.(the 826th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Cortex Mori nature and flavor are sweet, hot, and are cold.Return lung, spleen channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Cure mainly the fullness in the chest that lung-heat or diseases caused by retention of fluid stop lung and breath with cough hemoptysis, edema, beriberi, dysuria etc.(the 2787th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) property of medicine hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Cortex Lycii property of medicine is sweet, and is cold.Return lung, kidney channel.Has clearind deficient heat, purte the white, the effect of removing heat from blood.Can treat hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, the infantile malnutrition heating, dyspnea and cough due to lung-heat, haematemesis, epistaxis, hematuria are quenched one's thirst etc.(the 1141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Zingiberis property of medicine suffering, cold.Return spleen, lung meridian.Effect with line water detumescence.Can treat edema from the beginning of, dysuria etc.(the 927th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Ephedrae property of medicine suffering, little hardship, temperature.Return lung, urinary bladder channel.Has relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema.Can treat chill exterior syndrome, cough and asthma, edema due to wind pathogen, dysuria, rheumatic arthralgia, numbness of the skin, rubella pruritus, carbuncle of yin nature sucutaneous nodule etc.(the 3094th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali, Exocarpium Benincasae and Semen Phaseoli; With Gypsum Fibrosum, Cortex Mori, Rhizoma Atractylodis Macrocephalae (parched), Cortex Lycii, Poria and Herba Ephedrae is ministerial drug; With Semen Plantaginis, Radix Glycyrrhizae and Cortex Zingiberis is adjuvant.All medicines are harmonious, and are total to the tool benefiting QI for strengthening the superficies, the effect of inducing diuresis to remove edema.The treatment edema has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment edema of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat edema, and the prevention of edema is also had good effect, and the treatment edema has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment edema; Treatment edema patient 36 examples.Take embodiment 1 decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.28 examples of fully recovering account for 77.78%, and 6 examples that take a turn for the better account for 16.67%, and more 2 examples do not account for 5.55%, and total effective rate reaches 94.45%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction is pressed following weight weighting raw materials:
2 parts in 2 parts of Poria of 3 parts of Cortex Mori of Radix Astragali
1 part of 2 parts of Cortex Zingiberis of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
1 part in 2 portions of Radix Glycyrrhizaes of 3 parts of Cortex Lycii of Semen Phaseoli
0.6 part in 1 portion of Herba Ephedrae of 2 portions of Semen Plantaginiss of Gypsum Fibrosum.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment edema that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules are pressed following weight weighting raw materials:
2 parts in 2 parts of Poria of 3 parts of Cortex Mori of Radix Astragali
1 part of 2 parts of Cortex Zingiberis of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
1 part in 2 portions of Radix Glycyrrhizaes of 3 parts of Cortex Lycii of Semen Phaseoli
0.6 part in 1 portion of Herba Ephedrae of 2 portions of Semen Plantaginiss of Gypsum Fibrosum.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, two 2 to three times on the one, three months is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of edema is characterized in that it is made by following raw materials by weight proportions:
1.0~4 parts in 1.0~4 parts of Poria of 1.5~6 parts of Cortex Mori of Radix Astragali
0.1~2 part of 1.0~4 parts of Cortex Zingiberis of 1.5~6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
0.1~2 part in 1.0~4 portions of Radix Glycyrrhizaes of red little 1.5~6 parts of Cortex Lycii
0.3~1.2 part in 0.1~2 portion of Herba Ephedrae of 1.0~4 portions of Semen Plantaginiss of Gypsum Fibrosum.
2. a kind of Chinese medicine preparation for the treatment of edema according to claim 1, wherein the weight proportion of each crude drug is:
1.5~2.5 parts in 1.5~2.5 parts of Poria of 2.5~3.5 parts of Cortex Mori of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Cortex Zingiberis of 2.5~3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
0.5~1.5 part in 1.5~2.5 portions of Radix Glycyrrhizaes of 2.5~3.5 parts of Cortex Lycii of Semen Phaseoli
0.4~0.8 part in 0.5~1.5 portion of Herba Ephedrae of 1.5~2.5 portions of Semen Plantaginiss of Gypsum Fibrosum.
3. a kind of Chinese medicine preparation for the treatment of edema according to claim 1, wherein the weight proportion of each crude drug is:
2 parts in 2 parts of Poria of 3 parts of Cortex Mori of Radix Astragali
1 part of 2 parts of Cortex Zingiberis of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Exocarpium Benincasae
1 part in 2 portions of Radix Glycyrrhizaes of 3 parts of Cortex Lycii of Semen Phaseoli
0.6 part in 1 portion of Herba Ephedrae of 2 portions of Semen Plantaginiss of Gypsum Fibrosum.
CNA2008101037169A 2008-04-10 2008-04-10 Traditional Chinese medicine preparation for curing edematous Pending CN101249257A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991824A (en) * 2009-08-26 2011-03-30 栗素琴 Chinese medical preparation for treating cyesedema
CN102058863A (en) * 2010-11-24 2011-05-18 荣成市新技术应用研究所 Chinese medicinal composition for eliminating body edema
CN103212007A (en) * 2013-04-28 2013-07-24 赵道全 Traditional Chinese medicine preparation for treating abdominal distension of giant salamanders and preparation method of preparation
CN103520523A (en) * 2013-09-09 2014-01-22 吴承菊 Traditional Chinese medicine composition for treating edema
CN104012964A (en) * 2014-05-23 2014-09-03 秦翠梅 Method for infusing five-pericarp cicada
CN104116850A (en) * 2014-07-17 2014-10-29 董宝珍 Traditional Chinese medicinal liquor for treating edema and preparation method thereof
CN104208647A (en) * 2014-09-28 2014-12-17 卢仁华 Traditional Chinese medicine composition for treating tissue interstitial fluid
CN104825918A (en) * 2015-04-30 2015-08-12 刘德刚 Traditional Chinese medicine for treating edema

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991824A (en) * 2009-08-26 2011-03-30 栗素琴 Chinese medical preparation for treating cyesedema
CN102058863A (en) * 2010-11-24 2011-05-18 荣成市新技术应用研究所 Chinese medicinal composition for eliminating body edema
CN102058863B (en) * 2010-11-24 2012-03-28 王义玲 Chinese medicinal composition for eliminating body edema
CN103212007A (en) * 2013-04-28 2013-07-24 赵道全 Traditional Chinese medicine preparation for treating abdominal distension of giant salamanders and preparation method of preparation
CN103212007B (en) * 2013-04-28 2015-04-15 赵道全 Traditional Chinese medicine preparation for treating abdominal distension of giant salamanders and preparation method of preparation
CN103520523A (en) * 2013-09-09 2014-01-22 吴承菊 Traditional Chinese medicine composition for treating edema
CN103520523B (en) * 2013-09-09 2016-02-24 吴承菊 A kind of Chinese medicine composition for the treatment of edema
CN104012964A (en) * 2014-05-23 2014-09-03 秦翠梅 Method for infusing five-pericarp cicada
CN104116850A (en) * 2014-07-17 2014-10-29 董宝珍 Traditional Chinese medicinal liquor for treating edema and preparation method thereof
CN104208647A (en) * 2014-09-28 2014-12-17 卢仁华 Traditional Chinese medicine composition for treating tissue interstitial fluid
CN104825918A (en) * 2015-04-30 2015-08-12 刘德刚 Traditional Chinese medicine for treating edema

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