CN101085323A - Traditional Chinese medicine composition for treating uremia - Google Patents

Abstract

The invention relates to a Chinese medicinal combination for treating uremia which is prepared from more than ten kinds of Chinese medicinal herbs including pinellia tuber, lysimachia christinae, poria cocos wolf and dried tangerine peel.

Description

Treat uremic Chinese medicine composition

Technical field

The present invention relates to treat uremic Chinese medicine composition, is that a kind of uremia for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Uremia is the later stage performance of multiple kidney disease.Its course of disease is longer, that the clinical manifestation majority has is weak, indigestion and loss of appetite, nausea, vomiting, dizziness, headache, flank pain, edema, epistaxis; urine is not generally reduced, but the later stage obviously reduces big dry stool or half congealed thin; shallow complexion or ash stagnate; body of the tongue is how light fat or indentation is arranged, or light dim, pulse condition stringy and rapid pulse or count accurately; or heavy thin, or slow.The easy being invaded by exogenous pathogen of patient is so manyly when going to a doctor cause state of an illness aggravation because of being invaded by exogenous pathogen.

Uremia generally belongs to the scope of cards such as Chinese medicine " obstruction and rejection ", " difficulty in urination ", " edema ", " asthenia ".From the document record, most of patients is similar to the description of " obstruction and rejection "." card control converge mend the difficulty in urination " said: " both closed and lattice, must urinary obstruction, between morning and evening, increase vomiting and nausea suddenly, this is because of the turbid pathogen three warmers that are jammed, and healthy energy must not lifting.So close to descend and anuria, lattice should be gone up and give birth to vomiting, and it is exhausted that negative and positive are closed, in case promptly dead, marquis the most endangers.”

The traditional Chinese medical science thinks that the basis of chronic uremia is a deficiency of spleen-YANG and kidneyYANG, insufficiency of the spleenly then loses the precise and tiny effect of transporting and transforming nutrients from foodstuff, and suffering from a deficiency of the kidney then influences the function of separating clear and excreting turbid, thereby is stranded in the turbid damp, changes to form poison.It is weakened body resistance that deficiency of spleen-YANG and kidneyYANG belongs to, and being stranded in the turbid damp then is the domination of pathogen, so uremia is the card marquis of vital QI being weakened and pathogen being violent, is this with weakened body resistance, and the domination of pathogen is mark.Sick yin-yang all loss for a long time sees that cold and heat are staggered so late stage uremia is every, and deficiency and excess sees that also treatment is difficulty quite.

The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as spleen deficiency of kidney-QI, spleen kidney qi Yin bivacuity, the hepatic and renal YIN deficiency, deficiency of both YIN and YANG clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the uremic Chinese medicine composition of treatment.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 portions of Herba Lysimachiaes of 1.5～6 portions of Rhizoma Alismatis of Poria

1.0～4 parts on 1.0～4 parts of Folium Bambusaes of 1.0～4 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

1.0～4 parts of 1.0～4 parts of Rhizoma Acori Graminei of tangerine 1.0～4 parts of Fructus Aurantii Immaturuss

0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 0.1～2 portion of Radix Curcumae of Rhizoma Atractylodis.

The weight proportion of each raw material of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 portions of Herba Lysimachiaes of 2.5～3.5 portions of Rhizoma Alismatis of Poria

1.5～2.5 parts on 1.5～2.5 parts of Folium Bambusaes of 1.5～2.5 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Acori Graminei of tangerine 1.5～2.5 parts of Fructus Aurantii Immaturuss

0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 0.5～1.5 portion of Radix Curcumae of Rhizoma Atractylodis.

The weight proportion of each raw material of optimum formula of the present invention is:

3 parts of 3 portions of Herba Lysimachiaes of 3 portions of Rhizoma Alismatis of Poria

2 parts on 2 parts of Folium Bambusaes of 2 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

2 parts of 2 parts of Rhizoma Acori Graminei of tangerine 2 parts of Fructus Aurantii Immaturuss

0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 portion of Radix Curcumae of Rhizoma Atractylodis.

Drug action mechanism among the present invention is as follows:

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Herba Lysimachiae property of medicine, cold.Return liver, gallbladder, kidney, urinary bladder channel.Have heat clearing away, dampness removing, treating stranguria, calculus, antidotal effect.Can treat jaundice due to damp-heat, pyretic stranguria, oedema due to nephritis, liver, gallbladder and urinary system calculus, pyretic toxicity carbuncle, venom etc.(the 1967th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Folium Pyrrosiae property of medicine hardship, sweet, cold.Return lung, kidney, urinary bladder channel.Has relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, the effect of cooling blood for hemostasis.Can treat stranguria, edema, dysuria, the expectorant heat syndrome cough is breathed heavily, and spitting of blood is spitted blood epistaxis, metrorrhagia and traumatic hemorrhage etc.(the 811st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Folium Bambusae property of medicine is sweet, light, and is cold.GUIXIN, lung, stomach warp.Have clearing heat and relieving fidgetness, promote the production of body fluid, the diuretic effect.Can treat the calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, oliguria with reddish urine, erosion of the oral mucosa tongue boil etc.(the 1240th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Tangerine property of medicine suffering, hardship, temperature.Return lung, spleen channel.Has cold expelling dampness, the effect that activating QI to eliminate phlegm, alleviating distention in middle-JIAO are good for the stomach.Can treat the cough due to wind and cold, the abundant expectoration QI rising in reverse order, nausea and vomiting, breast gastral cavity painful abdominal mass is bloated etc.(the 3743rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Aurantii Immaturus property of medicine hardship, suffering are slightly cold.Return spleen, stomach, large intestine channel.Have the dispelling the stagnated QI removing food stagnancy, reduce phlegm except that the effect of painful abdominal mass.Can treat and stop in stagnant, the feeling of fullness distending pain, constipation, heavy behind the dysentery, blocked-up chest, the thoracic obstruction, gastroptosis, uterine prolapse, proctoptosis etc.(the 2231st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Acori Graminei property of medicine suffering, hardship, tepor.GUIXIN, liver, spleen channel.Have and eliminate phlegm for resuscitation, removing dampness to restore normal function of the stomach, the effect of mind calming benefit will.Can treat the calentura coma, syncope due to accumulation of phlegm, forgetful, insomnia, tinnitus, deafness, fasting dysentery, rheumatic arthralgia etc.(the 854th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Atractylodis property of medicine suffering, hardship, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, the effect that makes eye bright.Can treat the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, the exterior syndrome folder is wet, a heavy sensation of the body pain, arthromyodynia domination of damp pathogen, podomere are ached and are being weighed, and flaccidity is sprained, nyctalopia etc.(the 1485th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Poria, Rhizoma Alismatis and Herba Lysimachiae; With Pericarpium Citri Reticulatae, Folium Pyrrosiae, Folium Bambusae, dried tangerine peel, Fructus Aurantii Immaturus and Rhizoma Pinelliae Preparatum is ministerial drug; With Rhizoma Acori Graminei, Rhizoma Atractylodis and Radix Curcumae is adjuvant.All medicines are harmonious, tool clearing away heat-damp and promoting diuresis altogether, spleen invigorating and in effect.Treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment uremia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat uremia, and uremic prevention is also had good effect, and treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing medicine of the present invention, as follows through clinical test results to treating uremic therapeutic effect; Treatment uremic patient 13 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.Produce effects 5 examples account for 38.46%, and effective 5 examples account for 38.46%, and invalid 3 examples account for 23.08%, and total effective rate reaches 76.92%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

3 parts of 3 portions of Herba Lysimachiaes of 3 portions of Rhizoma Alismatis of Poria

2 parts on 2 parts of Folium Bambusaes of 2 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

2 parts of 2 parts of Rhizoma Acori Graminei of tangerine 2 parts of Fructus Aurantii Immaturuss

0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 portion of Radix Curcumae of Rhizoma Atractylodis.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The uremic decoction of the treatment that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, treat uremic Chinese medicine composition, it is characterized in that it is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 portions of Herba Lysimachiaes of 1.5～6 portions of Rhizoma Alismatis of Poria

1.0～4 parts on 1.0～4 parts of Folium Bambusaes of 1.0～4 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

1.0～4 parts of 1.0～4 parts of Rhizoma Acori Graminei of tangerine 1.0～4 parts of Fructus Aurantii Immaturuss

0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 0.1～2 portion of Radix Curcumae of Rhizoma Atractylodis.

2, the uremic Chinese medicine composition of treatment according to claim 1, wherein the weight proportion of each raw material is:

2.5～3.5 parts of 2.5～3.5 portions of Herba Lysimachiaes of 2.5～3.5 portions of Rhizoma Alismatis of Poria

1.5～2.5 parts on 1.5～2.5 parts of Folium Bambusaes of 1.5～2.5 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Acori Graminei of tangerine 1.5～2.5 parts of Fructus Aurantii Immaturuss

0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 0.5～1.5 portion of Radix Curcumae of Rhizoma Atractylodis.

3, the uremic Chinese medicine composition of treatment according to claim 1, wherein the weight proportion of each raw material is:

3 parts of 3 portions of Herba Lysimachiaes of 3 portions of Rhizoma Alismatis of Poria

2 parts on 2 parts of Folium Bambusaes of 2 parts of Folium Pyrrosiaes of Pericarpium Citri Reticulatae

2 parts of 2 parts of Rhizoma Acori Graminei of tangerine 2 parts of Fructus Aurantii Immaturuss

0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 portion of Radix Curcumae of Rhizoma Atractylodis.