CN101085179A - Traditional Chinese medicine preparation for treating uremia - Google Patents

Traditional Chinese medicine preparation for treating uremia Download PDF

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Publication number
CN101085179A
CN101085179A CN 200710117942 CN200710117942A CN101085179A CN 101085179 A CN101085179 A CN 101085179A CN 200710117942 CN200710117942 CN 200710117942 CN 200710117942 A CN200710117942 A CN 200710117942A CN 101085179 A CN101085179 A CN 101085179A
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parts
chinese medicine
portions
rhizoma
medicine preparation
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CN 200710117942
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CN 200710117942 priority Critical patent/CN101085179A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating uremia, which is prepared from more than ten kinds of Chinese medicinal herbs including prepared rehmannia root, bark of peony root, asphonin and red sage root.

Description

Treat uremic Chinese medicine preparation
Technical field
The present invention relates to treat uremic Chinese medicine preparation, is that a kind of uremia for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Uremia is the later stage performance of multiple kidney disease.Its course of disease is longer, that the clinical manifestation majority has is weak, indigestion and loss of appetite, nausea, vomiting, dizziness, headache, flank pain, edema, epistaxis; urine is not generally reduced, but the later stage obviously reduces big dry stool or half congealed thin; shallow complexion or ash stagnate; body of the tongue is how light fat or indentation is arranged, or light dim, pulse condition stringy and rapid pulse or count accurately; or heavy thin, or slow.The easy being invaded by exogenous pathogen of patient is so manyly when going to a doctor cause state of an illness aggravation because of being invaded by exogenous pathogen.
Uremia generally belongs to the scope of cards such as Chinese medicine " obstruction and rejection ", " difficulty in urination ", " edema ", " asthenia ".From the document record, most of patients is similar to the description of " obstruction and rejection "." card control converge mend the difficulty in urination " said: " both closed and lattice, must urinary obstruction, between morning and evening, increase vomiting and nausea suddenly, this is because of the turbid pathogen three warmers that are jammed, and healthy energy must not lifting.So close to descend and anuria, lattice should be gone up and give birth to vomiting, and it is exhausted that negative and positive are closed, in case promptly dead, marquis the most endangers.”
The traditional Chinese medical science thinks that the basis of chronic uremia is a deficiency of spleen-YANG and kidneyYANG, insufficiency of the spleenly then loses the precise and tiny effect of transporting and transforming nutrients from foodstuff, and suffering from a deficiency of the kidney then influences the function of separating clear and excreting turbid, thereby is stranded in the turbid damp, changes to form poison.It is weakened body resistance that deficiency of spleen-YANG and kidneyYANG belongs to, and being stranded in the turbid damp then is the domination of pathogen, so uremia is the card marquis of vital QI being weakened and pathogen being violent, is this with weakened body resistance, and the domination of pathogen is mark.Sick yin-yang all loss for a long time sees that cold and heat are staggered so late stage uremia is every, and deficiency and excess sees that also treatment is difficulty quite.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as spleen deficiency of kidney-QI, spleen kidney qi Yin bivacuity, the hepatic and renal YIN deficiency, deficiency of both YIN and YANG clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the uremic Chinese medicine preparation of treatment.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Salviae Miltiorrhizaes of 1.5~6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 portions of Rhizoma Dioscoreaes of Cortex Moutan
1.0~4 parts of 1.0~4 portions of Rhizoma Alismatis of 1.0~4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.1~2 part of 0.1~2 portion of Cortex Phellodendri of 0.1~2 part of Cherokee rose of Fructus Corni.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Salviae Miltiorrhizaes of 2.5~3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 portions of Rhizoma Dioscoreaes of Cortex Moutan
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Alismatis of 1.5~2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.5~1.5 part of 0.5~1.5 portion of Cortex Phellodendri of 0.5~1.5 part of Cherokee rose of Fructus Corni.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
2 parts in 2 parts of Poria of 2 portions of Rhizoma Dioscoreaes of Cortex Moutan
2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Cortex Phellodendri of 1 part of Cherokee rose of Fructus Corni.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Rosae Laevigatae property of medicine acid, puckery, flat.Return spleen, kidney, urinary bladder channel.Has controlling nocturnal emission with astringent drugs, reducing urination, astringing intestine to stop diarrhea, the effect of leukorrhagia stopping.Can treat seminal emission, spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, chronic dysentery, nebulousurine, leukorrhagia, metrorrhagia etc.(the 1976th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever , Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae Preparata, the Rhizoma Anemarrhenae and Radix Salviae Miltiorrhizae; With Cortex Moutan, Rhizoma Dioscoreae, Poria, Rhizoma Alismatis, Fructus Corni, Fructus Ligustri Lucidi and Herba Ecliptae is ministerial drug; With Cortex Phellodendri and Cherokee rose is adjuvant.All medicines are harmonious, tool enriching yin and nourishing kidney altogether, the effect of the controlling nocturnal emission with astringent drugs that nourishes blood.Treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment uremia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat uremia, and uremic prevention is also had good effect, and treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treating uremic therapeutic effect; Treatment uremic patient 11 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.Produce effects 4 examples account for 36.36%, and effective 5 examples account for 45.45%, and invalid 2 examples account for 18.18%, and total effective rate reaches 81.81%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
2 parts in 2 parts of Poria of 2 portions of Rhizoma Dioscoreaes of Cortex Moutan
2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Cortex Phellodendri of 1 part of Cherokee rose of Fructus Corni.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The uremic decoction of the treatment that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, treat uremic Chinese medicine preparation, it is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Salviae Miltiorrhizaes of 1.5~6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 portions of Rhizoma Dioscoreaes of Cortex Moutan
1.0~4 parts of 1.0~4 portions of Rhizoma Alismatis of 1.0~4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.1~2 part of 0.1~2 portion of Cortex Phellodendri of 0.1~2 part of Cherokee rose of Fructus Corni.
2, the uremic Chinese medicine preparation of treatment according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Salviae Miltiorrhizaes of 2.5~3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 portions of Rhizoma Dioscoreaes of Cortex Moutan
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Alismatis of 1.5~2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
0.5~1.5 part of 0.5~1.5 portion of Cortex Phellodendri of 0.5~1.5 part of Cherokee rose of Fructus Corni.
3, the uremic Chinese medicine preparation of treatment according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae Preparata
2 parts in 2 parts of Poria of 2 portions of Rhizoma Dioscoreaes of Cortex Moutan
2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi
1 part of 1 portion of Cortex Phellodendri of 1 part of Cherokee rose of Fructus Corni.
CN 200710117942 2007-06-26 2007-06-26 Traditional Chinese medicine preparation for treating uremia Pending CN101085179A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102091294A (en) * 2010-12-06 2011-06-15 济南金鼎信息技术有限公司 Traditional Chinese medicine composition for treating uremia
CN105796871A (en) * 2016-05-04 2016-07-27 宋毅 Traditional Chinese medicine composition for enriching yin and nourishing kidneys and preparation method of traditional Chinese medicine composition

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102091294A (en) * 2010-12-06 2011-06-15 济南金鼎信息技术有限公司 Traditional Chinese medicine composition for treating uremia
CN102091294B (en) * 2010-12-06 2012-04-18 吴怀英 Traditional Chinese medicine composition for treating uremia
CN105796871A (en) * 2016-05-04 2016-07-27 宋毅 Traditional Chinese medicine composition for enriching yin and nourishing kidneys and preparation method of traditional Chinese medicine composition

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Open date: 20071212