CN101095937A - Chinese traditional medicine for treating diabetic gastroparalysis - Google Patents

Chinese traditional medicine for treating diabetic gastroparalysis Download PDF

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Publication number
CN101095937A
CN101095937A CNA2007101183531A CN200710118353A CN101095937A CN 101095937 A CN101095937 A CN 101095937A CN A2007101183531 A CNA2007101183531 A CN A2007101183531A CN 200710118353 A CN200710118353 A CN 200710118353A CN 101095937 A CN101095937 A CN 101095937A
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China
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parts
rhizoma
parched
chinese medicine
stomach
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CNA2007101183531A
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101183531A priority Critical patent/CN101095937A/en
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Abstract

The invention relates to a Chinese medicament for treating diabetic stomach paralysis, which is prepared from more than ten kinds of Chinese medicinal herbs including astragalus root, rice sprout and perilla stem. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine of treatment diabetic gastroparalysis
Technical field
The present invention relates to treat a kind of Chinese medicine of diabetic gastroparalysis, is that a kind of diabetic gastroparalysis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic gastroparesis claims gastroparesis or gastric retention again, shows as the stomach hypotonia, and emptying delays.Food that is advanced before all vomiting 4~6h or early morning, residual quantity promptly was called gastric retention more than 200ml on an empty stomach.This is one of common gastral complication of diabetics.The absorption that can influence hypoglycemic medicine owing to the stomach hypotonia makes blood glucose fluctuation.Diabetic gastroparesis is equivalent to " vomiting ", " regurgitation " in the Chinese medicine.Chinese medicine thinks that vomiting takes place, and confuses lifting mistake department, the disease due to the stomach-QI being unable to descend normally mutually for taste are pure and impure.Beginning sense stomach discomfort, swollen vexed expanding satisfied, and food is received not good; The nausea and vomiting person who continues is called " regurgitation ", claims again " regurgitation of food from the stomach ", refers to that food enters in the stomach disease that can not mill spues immediately.Gu Yun: " eating in the morning but vomiting out in the evening, vomiting out in the morning what eaten at last night " refers to that gastric has dyspepsia and the vomiting that causes.With in " General Treatise on the Cause and Symptoms of Diseases ", pointing out for Chao Yuanfang (550-630 A.D.): " Rong Wei is all empty, its insufficiency of vital energy and blood, and the long-pending drink of cutting off the water is then dirty cold at gastral cavilty; dirty cold then spleen does not grind, and stomach does not grind then indigested food, and its QI rising in reverse order forms regurgitation also; eating in the morning but vomiting out in the evening then, and vomiting out in the morning what eaten at last night, the heart be the big as cup in jail down; contact as plug, vomiting right after eating very then, its tense and stringy pulse; tense pulse indicating existence of cold, string then be empty, deficiency and coldness is rich mutually; so vomiting right after eating is called regurgitation." Li Dongyuan says in " Treatise on the spleen and stomach ": " the vomiting sound of vomiting all belongs to weakness of the spleen and stomach, or cold and heat invade, or injury due to diet, causes the gas superinverse and must not eat." brilliantly to have discussed the taste lifting perverse, stomach is not accepted the enemy's surrender turbid, and spleen is the mill the lucid yang sending up not, indigestion, the pathogeny that superinverse is then told.Vomiting all has similarity with regurgitation in the cause of disease, pathology, symptom, so has nothing in common with each other, and vomits to be stomach-QI being unable to descend normally, and QI rising in reverse order is in last; Regurgitation is that the deficiency and coldness trip stagnates, and mouthful obstruction under the stomach is not due to pylorus is put.Main etiology and pathogenesis has the branch of deficiency and excess, and excess syndrome sees exopathogen and violates stomach, and onset is hurried; Retention of food and drink and hyperactive liver-QI attacking the stomach.Deficient syndrome then has Deficiency and coldness of spleen and stomach and deficiency of stomach-Yin etc.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic gastroparalysis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0~4.0 parts of 1.0~4 parts of Terra Flava Ustas of 1.5~6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
1.0~4.0 parts of 1.0~4 parts of Fructus Setariae Germinatus (parched) of 1.0~4 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.1~1.0 part of 0.1~2 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 0.1~2 part
0.1~0.5 part of 0.1~2 part of Fructus Amomi of 0.1~2 part of Caulis Perillae of Rhizoma Cyperi.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 parts of Terra Flava Ustas of 2.5~3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 parts of Fructus Setariae Germinatus (parched) of 1.5~2.5 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 0.5~1.5 part
0.2~0.4 part of 0.5~1.5 part of Fructus Amomi of 0.5~1.5 part of Caulis Perillae of Rhizoma Cyperi.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Terra Flava Ustas of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
2 parts of 2 parts of Fructus Setariae Germinatus (parched) of 2 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.5 part of 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 1 part
0.3 part of 1 part of Fructus Amomi of 1 part of Caulis Perillae of Rhizoma Cyperi.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Terra Flava Usta property of medicine suffering, temperature.Return spleen, stomach warp.Has the warming middle-JIAO hemostasis, preventing or arresting vomiting, antidiarrheal effect.Can treat deficiency and coldness and lose blood, vomiting is had loose bowels etc.(the 1258th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Pseudostellariae property of medicine is slightly cold.Return spleen, lung meridian.Has supplementing QI for promoting the production of body fluid, the effect of spleen reinforcing lung moistening.It is tired to treat insufficiency of the spleen body, inappetence, and impairment of both QI and YIN, dry cough expectorant is few, and spontaneous perspiration is breathed hard, and interior-heat is thirsty, the neurasthenia, palpitation and insomnia, dizzy forgetful, children's's summer fever etc.(the 534th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Setariae Germinatus (parched) nature and flavor are sweet, temperature.Return spleen, stomach warp.Have help digestion and in, the effect of spleen benefiting and stimulating the appetite.Can treat food stagnation and not disappear, abdominal distention halitosis, weakness of the spleen and stomach, not hungry lack of appetite.Fructus Setariae Germinatus (parched) relatively helps digestion, and is used for not hungry lack of appetite.The kind eliminate indigestion of Fructus Setariae Germinatus (parched to brown) stagnates, and is used for stagnant do not disappear etc.(the 142nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Rhizoma Zingiberis property of medicine suffering, heat.Return spleen, stomach, the heart, lung meridian.Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the effect of warm arteries and veins dissipating fluid-retention.Can treat coldness and pain in the epigastrium, vomiting is had loose bowels, and YANG-depletion is fainted contrary, and arthralgia due to cold-dampnes, cold fluid-retention are breathed with cough etc.(the 100th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fry Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Caulis Perillae nature and flavor suffering, temperature.Return lung, spleen channel.Has regulating the flow of QI to ease the stomach, pain relieving, antiabortive effect.It is vexed to administer the chest and diaphragm painful abdominal mass, gastralgia, belch vomiting, frequent fetal movement etc.(the 280th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Amomi property of medicine suffering, temperature.Return spleen, stomach, kidney channel.Has removing dampness, circulation of qi promoting, warming the spleen, antiabortive effect.Can treat retention of damp leading to blockage of QI, distension and fullness in the abdomen, anorexia, nausea and vomiting, stomachache is had loose bowels, pregnancy reactions, frequent fetal movement, metrorrhagia, all food poison etc.(the 2290th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Radix Astragali, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) and Rhizoma Zingiberis; With Rhizoma Atractylodis Macrocephalae (parched), Radix Pseudostellariae, Terra Flava Usta, Poria and Fructus Setariae Germinatus (parched) is ministerial drug; With frying Pericarpium Citri Reticulatae, Fructus Amomi, Rhizoma Cyperi and Caulis Perillae is adjuvant.All medicines are harmonious, the gentle spleen invigorating of tool altogether, the effect of regulating the stomach and sending down the abnormal ascending QI.The treatment diabetic gastroparalysis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic gastroparalysis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic gastroparalysis, and the prevention of diabetic gastroparalysis is also had good effect, and the treatment diabetic gastroparalysis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic gastroparalysis; Treatment diabetic gastroparalysis patient 15 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.5 examples of fully recovering account for 33.33%, and 7 examples that take a turn for the better account for 46.67%, and invalid 3 examples account for 20%, and total effective rate reaches 80%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Terra Flava Ustas of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
2 parts of 2 parts of Fructus Setariae Germinatus (parched) of 2 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.5 part of 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 1 part
0.3 part of 1 part of Fructus Amomi of 1 part of Caulis Perillae of Rhizoma Cyperi.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic gastroparalysis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine of treatment diabetic gastroparalysis is characterized in that it is made by the following weight proportion raw material:
1.0~4.0 parts of 1.0~4 parts of Terra Flava Ustas of 1.5~6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
1.0~4.0 parts of 1.0~4 parts of Fructus Setariae Germinatus (parched) of 1.0~4 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.1~1.0 part of 0.1~2 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 0.1~2 part
0.1~0.5 part of 0.1~2 part of Fructus Amomi of 0.1~2 part of Caulis Perillae of Rhizoma Cyperi.
2, a kind of Chinese medicine of treatment diabetic gastroparalysis according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 1.5~2.5 parts of Terra Flava Ustas of 2.5~3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
1.5~2.5 parts of 1.5~2.5 parts of Fructus Setariae Germinatus (parched) of 1.5~2.5 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 0.5~1.5 part
0.2~0.4 part of 0.5~1.5 part of Fructus Amomi of 0.5~1.5 part of Caulis Perillae of Rhizoma Cyperi.
3, a kind of Chinese medicine of treatment diabetic gastroparalysis according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Terra Flava Ustas of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of the Radix Astragali
2 parts of 2 parts of Fructus Setariae Germinatus (parched) of 2 parts of Radix Pseudostellariaes of Poria
Rhizoma Zingiberis is fried 0.5 part of 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of Pericarpium Citri Reticulatae for 1 part
0.3 part of 1 part of Fructus Amomi of 1 part of Caulis Perillae of Rhizoma Cyperi.
CNA2007101183531A 2007-07-05 2007-07-05 Chinese traditional medicine for treating diabetic gastroparalysis Pending CN101095937A (en)

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CNA2007101183531A CN101095937A (en) 2007-07-05 2007-07-05 Chinese traditional medicine for treating diabetic gastroparalysis

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Application Number Priority Date Filing Date Title
CNA2007101183531A CN101095937A (en) 2007-07-05 2007-07-05 Chinese traditional medicine for treating diabetic gastroparalysis

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CN101095937A true CN101095937A (en) 2008-01-02

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349774A (en) * 2013-07-24 2013-10-16 张立东 Drug for treating diabetes mellitus
CN104998177A (en) * 2015-07-03 2015-10-28 蔡涛 Externally-applied traditional Chinese medicine ointment used for treating diabetes
CN108143875A (en) * 2016-12-06 2018-06-12 北京中医药大学东方医院 A kind of Chinese medicine composition for treating diabetic gastroparesis and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349774A (en) * 2013-07-24 2013-10-16 张立东 Drug for treating diabetes mellitus
CN103349774B (en) * 2013-07-24 2015-04-29 张立东 Drug for treating diabetes mellitus
CN104998177A (en) * 2015-07-03 2015-10-28 蔡涛 Externally-applied traditional Chinese medicine ointment used for treating diabetes
CN108143875A (en) * 2016-12-06 2018-06-12 北京中医药大学东方医院 A kind of Chinese medicine composition for treating diabetic gastroparesis and preparation method thereof
CN108143875B (en) * 2016-12-06 2020-09-11 北京中医药大学东方医院 Traditional Chinese medicine composition for treating diabetic gastroparesis and preparation method thereof

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