CN101085255A - Traditional Chinese medicine preparation for treating acute nephritis - Google Patents

Traditional Chinese medicine preparation for treating acute nephritis Download PDF

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Publication number
CN101085255A
CN101085255A CN 200710117902 CN200710117902A CN101085255A CN 101085255 A CN101085255 A CN 101085255A CN 200710117902 CN200710117902 CN 200710117902 CN 200710117902 A CN200710117902 A CN 200710117902A CN 101085255 A CN101085255 A CN 101085255A
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parts
chinese medicine
radix
rhizoma
acute nephritis
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CN 200710117902
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CN 200710117902 priority Critical patent/CN101085255A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating acute nephritis which is prepared from more than ten kinds of Chinese medicinal herbs including raw astragalus root, cogongrass rhizome, small thistle and raspberry.

Description

A kind of Chinese medicine preparation of treatment acute nephritis
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of acute nephritis, is that a kind of acute nephritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Acute glomerulonephritis is called for short acute nephritis, is clinical common kidney disease.Acute onset is common clinical manifestation with hematuria, albuminuria, hypertension, edema, oliguria and azotemia.This is one group of clinical syndrome, is referred to as acute nephritic syndrome again.Most clinically acute poststreptococcal glomerulonephritises that belong to.TCM Document does not have this title of acute nephritis, belongs to " edema due to wind pathogen ", " YANG edema " and categories such as " hematuria " in motherland's medical science " edema "." edema " speech sees " element is asked hydro-thermal cave opinion " " lung is a dyspnea with stridor, and kidney is an edema " the earliest.In addition, according to the disease of primary disease hematuria, " element is asked the opinion of losing consciousness " cloud: " the uterus transferring pathogenic heat to the urinary bladder is then infirmity, hematuria ".In " the sick piece of writing of Medical Treasures of the Golden Chamber accumulation of pathogenic wind cold in five ZANG-organs " " heat in lower-JIAO is hematuria then ", be the record of acute nephritis hematuria syndrome.
Primary disease is more common in the child, and sending out the age well is 5~14 years old.In less involving, the old people, only account for below 10% of total number of the infected more than 40 years old.Rare morbidity below 2 years old.M-F is 2 to 1.Incubation period: most patients has the forerunner to infect history, and the lighter can FFI clinical manifestation.The order of severity of nephritis does not depend on the order of severity that the forerunner infects.1~3 week began to occur the clinical symptoms of nephritis after the streptococcal infection, on average about 10 days of incubation period, and also may be shorter.General skin infection than person due to the upper respiratory tract infection for long.The former mostly is 14~21 days, the latter mostly is 6~12 days.Surpass 3 all persons rare incubation period.Part patient can have one to cross slight albuminuria of property and microscopic hematuria in course of infection, may be with heating, that streptococcic erythrogenic toxin acts on GBM is relevant.
The traditional Chinese medical science is thought " institute of heresy gathers, and its gas must be empty, and deficiency of YIN person's sun must gather it ".Not outer inside and outside two ends of the cause of disease of acute nephritis.With regard to interior thereby speech, mainly be the natural endowment deficiency, or the day after tomorrow intemperance of taking food, work and rest is improper, nurses one's health inappropriately, causes deficiency of spleen and stomach.How the exopathogenic factor aspect is then attacked outward because of six climate exopathogens, and sore caves in.
Positive QI-insufficiency exopathogen invasion in addition is the main cause that acute nephritis takes place, and sick position is mainly at kidney, but closely related with lung, spleen.Syndrome develop trend be from table and in, reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels by the part of the body cavity above the diaphragm housing the heart and lungs, middle Jiao, be mainly to develop to vital QI being weakened and pathogen being violent, simulataneous insufficiency and excessive gradually from marking real.The pathological process that the acute edema phase strives for the good and evil play, the edema extinction phase then enters the deficient vital QI leading to lingering of pathogen stage.If make vital QI recovered after pathogens eliminated by treatment, then can make the patient to more, control wrong treatment otherwise lose, the state of an illness also can develop intensification, so that the five internal organs are all sick, all cards are grown thickly, the delay refractory, severe patient can have the heart attacked by pathogenic water, on cover clear key, even kidney unit is depleted, and blood vessels are obstructed, noxious dampness retention, threat to life.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of acute nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Rhizoma Imperataes of 1.5~6 parts of Radix Astragali of Herba Cirsii
1.0~4 parts of 1.0~4 parts of Cortex Moutans of 1.0~4 parts of Radix Rehmanniae Preparata of Radix Codonopsis
1.0~4 parts of 1.0~4 portions of Rhizoma Dioscoreaes of 1.0~4 portions of Fructus Rubies of Rhizoma Alismatis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of Fructus Corni of Ramulus Cinnamomi.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Rhizoma Imperataes of 2.5~3.5 parts of Radix Astragali of Herba Cirsii
1.5~2.5 parts of 1.5~2.5 parts of Cortex Moutans of 1.5~2.5 parts of Radix Rehmanniae Preparata of Radix Codonopsis
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Dioscoreaes of 1.5~2.5 portions of Fructus Rubies of Rhizoma Alismatis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of Fructus Corni of Ramulus Cinnamomi.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Radix Astragali of Herba Cirsii
2 parts of 2 parts of Cortex Moutans of 2 parts of Radix Rehmanniae Preparata of Radix Codonopsis
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 portions of Fructus Rubies of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Fructus Corni of Ramulus Cinnamomi.
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Herba Cirsii property of medicine, cold.Return liver, spleen channel.Has cooling blood for hemostasis, the effect of removing toxic substances and promoting subsidence of swelling.Can treat hematuria, stranguria with blood, hemoptysis is spitted blood, and epistaxis is had blood in stool, dysentery, metrorrhagia and metrostaxis, traumatic hemorrhage, swollen ulcer drug etc.(the 331st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Imperatae property of medicine is sweet, and is cold.GUIXIN, lung, stomach, urinary bladder channel.Has clearing away heat and promoting production of body fluid, cooling blood for hemostasis, the effect of inducing diuresis for treating stranguria syndrome.Can treat the calentura excessive thirst, dyspnea and cough due to lung-heat, the gastric heat vomiting, heat in blood is hemorrhage, the puckery pain of dribbling urination, edema, jaundice etc.(the 992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Rubi property of medicine is sweet, sour, tepor.Return liver, kidney channel.Has the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, the effect that makes eye bright.Can treat impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, and the frequent micturition incontinence of urine is visual dim, early whitening of beard and hair etc.(the 3813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Ramulus Cinnamomi property of medicine suffering, sweet, temperature.Return bladder, the heart, lung meridian.Has expelling cold and relieving exterior syndrome, warming the meridian, the effect of activating yang.Can treat exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea , mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria etc.(the 2522nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Herba Cirsii, Radix Astragali and Rhizoma Imperatae; With Radix Codonopsis, Radix Rehmanniae Preparata, Cortex Moutan, Rhizoma Alismatis, Fructus Rubi and Rhizoma Dioscoreae is ministerial drug; With Ramulus Cinnamomi, Fructus Corni and Radix Aconiti Lateralis Preparata is adjuvant.All medicines are harmonious, and are total to the tool replenishing QI to invigorate the spleen, the kidney warming hemostatic effect.The treatment acute nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment acute nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat acute nephritis, and the prevention of acute nephritis is also had good effect, and the treatment acute nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment acute nephritis; Treatment acute nephritis patient 13 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 53.85%, and 4 examples that take a turn for the better account for 30.77%, and more 2 examples do not account for 15.38%, and total effective rate reaches 84.62%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Radix Astragali of Herba Cirsii
2 parts of 2 parts of Cortex Moutans of 2 parts of Radix Rehmanniae Preparata of Radix Codonopsis
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 portions of Fructus Rubies of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Fructus Corni of Ramulus Cinnamomi.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment acute nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation of treatment acute nephritis is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Rhizoma Imperataes of 1.5~6 parts of Radix Astragali of Herba Cirsii
1.0~4 parts of 1.0~4 parts of Cortex Moutans of 1.0~4 parts of Radix Rehmanniae Preparata of Radix Codonopsis
1.0~4 parts of 1.0~4 portions of Rhizoma Dioscoreaes of 1.0~4 portions of Fructus Rubies of Rhizoma Alismatis
0.1~1 part of 0.1~2 part of Radix Aconiti Lateralis Preparata of 0.1~2 part of Fructus Corni of Ramulus Cinnamomi.
2, a kind of Chinese medicine preparation of treatment acute nephritis according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Rhizoma Imperataes of 2.5~3.5 parts of Radix Astragali of Herba Cirsii
1.5~2.5 parts of 1.5~2.5 parts of Cortex Moutans of 1.5~2.5 parts of Radix Rehmanniae Preparata of Radix Codonopsis
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Dioscoreaes of 1.5~2.5 portions of Fructus Rubies of Rhizoma Alismatis
0.3~0.7 part of 0.5~1.5 part of Radix Aconiti Lateralis Preparata of 0.5~1.5 part of Fructus Corni of Ramulus Cinnamomi.
3, a kind of Chinese medicine preparation of treatment acute nephritis according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Radix Astragali of Herba Cirsii
2 parts of 2 parts of Cortex Moutans of 2 parts of Radix Rehmanniae Preparata of Radix Codonopsis
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 portions of Fructus Rubies of Rhizoma Alismatis
0.5 part of 1 part of Radix Aconiti Lateralis Preparata of 1 part of Fructus Corni of Ramulus Cinnamomi.
CN 200710117902 2007-06-26 2007-06-26 Traditional Chinese medicine preparation for treating acute nephritis Pending CN101085255A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058753A (en) * 2010-12-29 2011-05-18 江西百神药业集团有限公司 Medicament for replenishing qi to invigorate spleen and preparation method
CN102106978B (en) * 2009-12-28 2013-02-13 李心亭 Medicament for treating nephritis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106978B (en) * 2009-12-28 2013-02-13 李心亭 Medicament for treating nephritis
CN102058753A (en) * 2010-12-29 2011-05-18 江西百神药业集团有限公司 Medicament for replenishing qi to invigorate spleen and preparation method
CN102058753B (en) * 2010-12-29 2012-01-11 江西百神药业集团有限公司 Medicament for replenishing qi to invigorate spleen and preparation method

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Open date: 20071212