CN101085312A - Traditional Chinese medicine for treating hyperdyroidism - Google Patents

Abstract

The invention relates to a Chinese medicament for treating hyperthyroidism which is prepared from more than ten kinds of Chinese medicinal herbs including radix paeoniae rubrathe, radix salvia miltiorrhiza and prunella spike.

Description

A kind of Chinese medicine for the treatment of hyperthyroidism

Technical field

The present invention relates to a kind of Chinese medicine for the treatment of hyperthyroidism, is that a kind of to treat hyperthyroidism be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Hyperthyroidism (abbreviation hyperthyroidism) is meant that the thyroxin that is caused by multiple reason increases, and acts on the histoorgan of whole body, causes system's irritabilitys such as nerve, circulation, digestion of body to increase and hypermetabolism is the general name of the disease of main performance.It is the common big class disease of hormonal system.The primary disease onset is slow, and direct stimulation is major incentive as fear, sadness, rage etc.The performance of model case hypermetabolism disease group, high neural excitation, goiter and oculopathy several respects is all more obvious; The state of an illness is obscured with neurosis mutually than the lighter is easy.The patient who has serves as main performance with some characteristic symptom such as expophthalmos, cachexia or myopathy etc. often.Performance old and child patient often is not true to type.In recent years, owing to improving constantly of diagnostic level, the light disease and the patient that is not true to type also can find early.Hyperthyroidism belongs to categories such as Chinese medicine " goiter ", " melancholia ", " asthenia ".Diffuse goiter companion hyperthyroidism is an autoimmune disease that can involve each system of whole body, and its treatment has antithyroid drug, subtotal thyroidectomy, radioiodine therapy etc.The Drug therapy relapse rate is higher, accounts for 40%～50%.If malpractice or recurrence are not repeatedly touchingly healed, can cause serious hyperthyroid heart disease, even heart failure, serious arrhythmia, hyperthyroidism periodic paralysis, patient disability be can make and quality of life, very then threat to life influenced.Hyperthyroidism crisis is a critical emergency case of hyperthyroidism, and mortality rate reaches 50%～70%, so answer active prevention, diagnosis is in time rescued with all strength, to save patient's life.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of hyperthyroidism.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the raw material of following weight optimum ratio:

1.5～6 parts of 1.5～6 parts of Spica Prunellaes of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

1.0～4 parts of 1.0～4 portions of Herba Ecliptaes of 1.0～4 parts of Fructus Ligustri Lucidi of Radix Curcumae

0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.0～4 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.1～1 part of 0.1～2 part of Rhizoma Pinelliae of 0.1～2 part of Spina Gleditsiae of Radix Scrophulariae.

The best proportioning of the weight of each raw material of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Spica Prunellaes of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

1.5～2.5 parts of 1.5～2.5 portions of Herba Ecliptaes of 1.5～2.5 parts of Fructus Ligustri Lucidi of Radix Curcumae

0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 1.5～2.5 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae of 0.5～1.5 part of Spina Gleditsiae of Radix Scrophulariae.

The weight proportion of each raw material of optimum formula of the present invention is:

3 parts of 3 parts of Spica Prunellaes of 3 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

2 parts of 2 portions of Herba Ecliptaes of 2 parts of Fructus Ligustri Lucidi of Radix Curcumae

1 part of 2 parts of Cortex Moutan of 2 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.5 part of 1 part of Rhizoma Pinelliae of 1 part of Spina Gleditsiae of Radix Scrophulariae.

Drug action mechanism among the present invention is as follows:

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Spica Prunellae property of medicine hardship, suffering, cold.Return liver, gallbladder meridian.Has liver heat removing and eyesight improving, the effect of powder detoxifcation.Can treat the conjunctival congestion photophobia, ophthalmalgia, it is dizzy to have a headache, tinnitus, scrofula goiter, acute mastitis mumps, carbuncle furuncle and phyma poison, acute and chronic hepatitis, hypertension etc.(the 2562nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Magnoliae Officinalis property of medicine hardship, suffering, temperature.Return stomach, large intestine channel.Has the circulation of qi promoting intestinal stasis relieving, dampness, the effect of lowering the adverse QI to relieve asthma.Can treat stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough etc.(the 2284th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Spina Gleditsiae property of medicine suffering, temperature.Return liver, lung, stomach warp.Have the saturating pus of detumescence, search wind, parasiticidal effect.Can treat swollen ulcer drug, scrofula, leprosy, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, Cortex Dictamni property of medicine hardships, salty such as placenta retention, cold.Return spleen, stomach warp.Has heat clearing and damp drying, dispelling wind for relieving itching, detoxifcation.Can treat the rubella eczema due to the wind heat noxious dampness, scabies, jaundice, rheumatism pyretic arthralgia etc.(the 1595th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Pinelliae property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Paeoniae Rubra, Spica Prunellae and Radix Salviae Miltiorrhizae; With Radix Curcumae, Fructus Ligustri Lucidi, Herba Ecliptae, Radix Bupleuri magnolia obovata is ministerial drug; With Cortex Moutan, Radix Scrophulariae, Spina Gleditsiae and Rhizoma Pinelliae is adjuvant.All medicines are harmonious, altogether the effect of tool dispersing the stagnated live-QI to relieve the stagnation of QI, dissipating phlegm and resolving masses.The treatment hyperthyroidism has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment hyperthyroidism of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat hyperthyroidism, and the prevention of hyperthyroidism is also had good effect, and the treatment hyperthyroidism has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment hyperthyroidism; Treatment hyperthyroid patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 33.33%, and 8 examples that take a turn for the better account for 44.44%, and more 4 examples do not account for 22.22%, and total effective rate reaches 77.77%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

3 parts of 3 parts of Spica Prunellaes of 3 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

2 parts of 2 portions of Herba Ecliptaes of 2 parts of Fructus Ligustri Lucidi of Radix Curcumae

1 part of 2 parts of Cortex Moutan of 2 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.5 part of 1 part of Rhizoma Pinelliae of 1 part of Spina Gleditsiae of Radix Scrophulariae.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment hyperthyroidism that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine for the treatment of hyperthyroidism is characterized in that it is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 parts of Spica Prunellaes of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

1.0～4 parts of 1.0～4 portions of Herba Ecliptaes of 1.0～4 parts of Fructus Ligustri Lucidi of Radix Curcumae

0.1～2 part of 1.0～4 parts of Cortex Moutan of 1.0～4 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.1～1 part of 0.1～2 part of Rhizoma Pinelliae of 0.1～2 part of Spina Gleditsiae of Radix Scrophulariae.

2, a kind of Chinese medicine for the treatment of hyperthyroidism according to claim 1, wherein the weight proportion of each raw material is:

2.5～3.5 parts of 2.5～3.5 parts of Spica Prunellaes of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

1.5～2.5 parts of 1.5～2.5 portions of Herba Ecliptaes of 1.5～2.5 parts of Fructus Ligustri Lucidi of Radix Curcumae

0.5～1.5 part of 1.5～2.5 parts of Cortex Moutan of 1.5～2.5 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae of 0.5～1.5 part of Spina Gleditsiae of Radix Scrophulariae.

3, a kind of Chinese medicine for the treatment of hyperthyroidism according to claim 1, wherein the weight proportion of each raw material is:

3 parts of 3 parts of Spica Prunellaes of 3 parts of Radix Salviae Miltiorrhizaes of Radix Paeoniae Rubra

2 parts of 2 portions of Herba Ecliptaes of 2 parts of Fructus Ligustri Lucidi of Radix Curcumae

1 part of 2 parts of Cortex Moutan of 2 parts of Radix Bupleuri of Cortex Magnoliae Officinalis

0.5 part of 1 part of Rhizoma Pinelliae of 1 part of Spina Gleditsiae of Radix Scrophulariae.