CN102106978B - Medicament for treating nephritis - Google Patents
Medicament for treating nephritis Download PDFInfo
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- CN102106978B CN102106978B CN2009102601789A CN200910260178A CN102106978B CN 102106978 B CN102106978 B CN 102106978B CN 2009102601789 A CN2009102601789 A CN 2009102601789A CN 200910260178 A CN200910260178 A CN 200910260178A CN 102106978 B CN102106978 B CN 102106978B
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Abstract
The invention discloses a medicament for treating nephritis, which is prepared from the following raw materials by weight: 1,000 grams of glucose, 4.5 grams of vitamin C, 150 grams of kidney qi pills, 60 grams of kidney boost tables, 500 milliliters of artificial hematinic liquid, 100 grams of corn stigma, 15 Chinese dates and 4.2 kilograms of water, and the components are prepared into oral liquid by the conventional method. The medicament has the effects of tonifying qi, promoting blood circulation, tonifying liver and kidney, supplying vital essence and marrow and enhancing the immunity oforganisms, has the effect of curing and rehabilitating kidney diseases, is non-toxic and harmless to human bodies, and is not bitter nor astringent and convenient to take. Cases are selected during years of clinical observation, one month is one treatment course, the medicament is taken for three times a day, and one bottle is taken at each time; about 500 patients are cured, cure means the patients are rehabilitated completely, and effectiveness means the condition of the patients has a favorable turn; and the cure rate is 85 percent, and the total effective rate is 95 percent.
Description
Technical field the invention belongs to technical field of pharmaceuticals, is specifically related to a kind of medicine for the treatment of nephritis.
Background technology nephritis is divided into constitutional and Secondary cases two large classes, is called nephrotic syndrome when High-grade Proteinuria is arranged.Primary Nephritis refers to the inflammation of glomerule itself, is divided into again acute and chronic two kinds, and chronic nephritis is also divided multiple histological type, and IgA nephropathy is the most common.Secondary cases nephritis refers to the nephritis that other position diseases of health cause.Almost the disease of each system of health can cause nephritis, and nephropathy usually is to determine the most important factor of coincident with severity degree of condition, such as systemic lupus erythematosus (sle) and vasculitis etc.The common disease that causes nephritis comprises that autoimmune disease such as lupus erythematosus, vasculitis, rheumatoid arthritis, sjogren syndrome, anaphylactoid purpura, infection amygdala are scorching, hepatitis hepatitis B etc. especially.
The nephritis that we say usually refers to glomerulonephritis, is a topmost class in the nephritis, and glomerulonephritis mainly contains following several clinically:
1, acute nephritis: onset is anxious, weight differs.Its performance: albuminuria, hematuria (mostly being gross hematuria), edema (can gently can weigh), hypertension (how relevant with edema), oliguria, a mistake property azotemia, can be with weak, anorexia, nauseating, vomiting, pain in the lumbar region, stomachache etc.Be found in each age group, but be common in 6-10 year child.
2, nephrotic syndrome: High-grade Proteinuria (" 3.5g/24 hour), proteinemia (" 30 grams per liters), edema (relevant with hypoproteinemia), the cholesterol (" 6MMD/L that raises) etc.
3, IgA nephropathy: repeatedly show effect, have naked eyes or lasting microscopic hematuria, can be with in various degree albuminuria, occult blood, being everlasting occurs after the respiratory tract infection, shows as the symptoms such as silent urine is unusual, chronic nephritis, nephrotic syndrome, lumbago (one-sided or bilateral).Be more common in person between twenty and fifty.
4, chronic nephritis: onset is hidden, makes slow progress, can gently can be weighed, urine examination is unusual, with edema, anemia, hypertension, azotemia etc., often bring out because of upper respiratory tract infection etc. that it is increased the weight of, with nephrotic syndrome, chronic nephritis acute attack, similar acute nephritis etc.
5, lupus nephritis: be by systemic lupus erythematosus (sle) secondary renal damage, be common in young women, Most patients the systemic lupus erythematosus (sle) symptom occurs first such as fever skin lesion, multiple arthralgia etc., nephropathy occurs clinically, also occurs and just occur the performance of getting involved of whole body system after the nephropathy.The performance of its nephropathy has light-duty asymptomatic nephritis (only have urine examination unusual), nephrotic syndrome, universality chronic nephritis, strive into nephritis etc.
6, henoch Schonlein purpura nephritis: be the nephropathy by the anaphylactoid purpura secondary, be common in child's (men and women's ratio is about 5: 1), the anaphylactoid purpura symptom is arranged first mostly, nephropathy then occurs, it is characterized by nephrotic syndrome or chronic nephritic syndrome etc.
7, hepatitis B associated glomerulonephritis: be the glomerule infringement that hepatitis B causes, often show as that asymptomatic albuminuria and hematuria, acute nephritis are comprehensive, nephrotic syndrome and renal insufficiency etc.
In the past few years this disease shows a rising trend.At present, clinical main by Chinese herbal medicine and Western medicine Drug therapy, medicament effective component scattered and disappeared large when the former decocted; The latter needs long-term medication, and financial burden increases the weight of.Especially take heavy dose of Western medicine and can bring out the side effect such as other diseases, and manufacturing process is complicated, production cost is high.
Summary of the invention the purpose of this invention is to provide a kind ofly improve immunity of organisms, treating both the principal and secondary aspects of a disease, have no side effect, the medicine of cheap, treatment nephritis that cure rate is high, to remedy the deficiencies in the prior art.
Solution of the present invention is based on motherland's medical science to understanding and the Therapeutic Principle of the pathogeny of nephritis and raising immunity of organisms, with reference to ancient, modern pharmacological research achievement, the Chinese and western medicine Comprehensive Treatment, make its performance promote that yang blood and qi is regulated in the human body, vital organs of the human body twelve channels and collaterals balance, benefit invigorating the liver and kidney, vital essence replenishing and marrow benifiting have the effect of healing and rehabilitation to treatment nephritis.
Medicine of the present invention is made by following drug component proportioning:
Glucose 1000g, vitamin C 4.5g, shenqi pill 150g, kidney tonifying sheet 60g, artificial liquor for tonifying blood 500ml, Stigma Maydis 100g, 15 pieces in Fructus Jujubae, water 4.2Kg;
Above-mentioned each component is made oral liquid according to a conventional method, finishes in the steps below successively:
1), pretreatment: slice lapping becomes powder with kidney tonifying with vitamin C, and shenqi pill is broken, and is for subsequent use;
2), stew soup: with Stigma Maydis, Fructus Jujubae and water boil 20 minutes, be cooled to 30 ℃ of filtrations, filtrate for later use;
3), the preparation medicinal liquid: with step 1) fine powder that grinds, broken shenqi pill and the glucose in the component, artificial liquor for tonifying blood, add step 2) in the filtrate, mix homogeneously;
4), bottling: with step 3) medicinal liquid that makes, in the 100ml medicinal liquid bottle of the in advance sterilization of packing into, namely get medicine oral liquid of the present invention.
Glucose in the medicine of the present invention, main source for body institute energy requirement, be oxidized in vivo carbon dioxide and water and supply with simultaneously heat, or store with the glycogen form, can promote the function of detoxification of liver, liver there is protective effect, it is indispensable material in the vital movement, it can participate in metabolic processes directly in human body, in digestive tract, glucose all is absorbed easily than any other monosaccharide, and can be directly after being absorbed be the tissue utilization, except to the diabetes patient, glucose does not have any side effect, pharmacological action: moisture and sugar in the energy added body have additional body fluid, supply with energy, replenish blood glucose, the heart tonifying diuresis, the effects such as detoxifcation; Vitamin C has stronger reduction, and participates in multiple redox reaction in the human body; it can make a part of enzyme keep reducing condition; protective enzyme is active, keeps the balance of cellular metabolism, promotes the generation of intercellular substance; promote the healing of wound; the resistance of enhancing body, the formation of enhancing antibody has infection, antiviral effect; vitamin C has Detoxication to noxious substance, is described as omnipotent antidote.Vitamin C can alleviate and prevent and treat since harmful chemical such as hydrargyrum, lead, benzene, arsenic etc. to the murder by poisoning of human body, strengthen the function of detoxification of liver, promote the hemopoietic function, promote the utilization of ferrum absorption and folic acid, the fragility of cholesterol reducing and blood capillary, to prevent and treat hypercholesterolemia, atherosclerosis has certain effect, vitamin C also has antitumaous effect; Shenqi pill, be also referred to as JINGUI SHENQI WAN, effect with temperature compensation kidney qi, cure mainly that deficiency of kidney-QI, soreness of waist foot are soft, limbs fear of cold, cramp and pain in the lower abdomen, dysuria or frequency, pale tongue are fat, the chi deep-thready pulse and phlegm retention is breathed with cough, the edema beriberi, quench one's thirst, chronic diarrhea, now be mainly used in the person that belongs to the deficiency of kidney-QI such as hypothyroidism, chronic nephritis, hypoadrenocorticism and bronchial asthma; The kidney tonifying sheet, effect with kidney tonifying, essence replenishing, QI invigorating tonifying YANG, strengthening the body resistance is mainly used in the treatment diseases such as lumbago caused, seminal emission, sexual impotence, premature ejaculation of suffering from a deficiency of the kidney, artificial liquor for tonifying blood, be also referred to as ferric ammonium citrate dimension B1 syrup OTC first (artificial hematonic), belong to the anti-anemic drug thing; Stigma Maydis, property slightly sweet flavor and putting down, enter liver, kidney, urinary bladder channel, inducing diuresis to remove edema is arranged, the function of suppressing the hyperactive liver function of gallbladder promoting, cure mainly urgency, chronic nephritis, edema, acute cholecystitis, Biliary Calculi and hypertension etc., modern pharmacological research shows, Stigma Maydis contains a large amount of potassium nitrate, vitamin K, sitoesterol, stigmasterol and a kind of volatile alkaloid, diuresis is arranged, blood pressure lowering, blood sugar lowering, hemostasis, the effects such as function of gallbladder promoting, so a lot of by the proved recipe that principal agent is formed take this product, it is also very extensive to cure the disease, and has: 1. diuresis: Stigma Maydis all has diuresis to people or rabbit, can increase the chloride output, but a little less than the effect.The insoluble part of its aqueous extract methanol is the strongest through dialysis person's (first) diuresis, and no matter oral, subcutaneous or intravenous injection all has remarkable result.Diuresis mainly is the outer property of kidney, and is very weak to the effect of kidney; 2. to the effect of blood circulation: anesthetized dog intravenous injection decoct has remarkable hypotensive effect, but to chronic carotid skin bridge Canis familiaris L., take medicine every day, in continuous 3 weeks, there is no hypotensive effect.First has dilating effect to peripheral vessel when low concentration; 3. blood sugar lowering effect: the fermentation preparation of Stigma Maydis has the blood sugar lowering effect of highly significant to rabbit; 4. function of gallbladder promoting, anastalsis: made from corn stigma can promote bile excretion, reduce its viscosity, reduce its bile pigments content, thereby can be used as choleretic for the cholangitis patient of uncomplicated chronic cholecystitis, bile discharge obstacle, it can also accelerate Blood Coagulation Process, increase prothrombing content in the blood, improve platelet count, be applied to bladder and lithangiuria so can be used as the hemorrhage diuretic of holding concurrently, cure mainly oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis; Fructus Jujubae claims again Fructus Jujubae, all on the books in a lot of medical ancient books and records of China, " book on Chinese herbal medicine is looked for the truth " middle finger mountain: " people's Fructus Jujubae sweet in the mouth, warm in nature, for the tonifying the spleen and stomach key medicine, can moisten cardiopulmonary, tonifying five ZANG-organs, rich muscle, improving healthy complexion, born fluid, control deficient, Fructus Jujubae sweet can invigorating middle warmer, temperature can QI invigorating." claiming in the essentials of Matea Medica can " invigorating the spleen and replenishing QI, taste spleen soil, the profit cardiopulmonary, transfer battalion to defend, slow cloudy blood, born fluid, improving healthy complexion, logical nine orifices, help 12 warps and hundred medicines "; clinically; be commonly used to treat weakness of the spleen and stomach; insufficiency of vital energy and blood; disharmony of nutrient QI with defensive QI; disease and the solution poison of drug such as severe palpitation, it is generally acknowledged, contain abundant saccharide in the Fructus Jujubae, vitamin A, B1, B2, C, P and alkaloid, Flavonoid substances, also contain calcium, ferrum, selenium, the trace element such as manganese and tens seed amino acids are material bases of its pharmacological effect function, therefore China's Ministry of Public Health is formally classified Fructus Jujubae as " being food; also be medicine ", Fructus Jujubae can be treated anemia, make the erythrocyte of animal, the blood constituents such as hemoglobin all have increase in various degree, have blood tonification effect.Medicine of the present invention has specially good effect through reasonable compatibility to nephropathy.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, each component of medicine of the present invention meets pharmaceutical control law regulation, utilizes the comprehensive function treatment nephropathy of the medicine of respectively distinguishing the flavor of, and has the effect of tonifying QI to promote blood circulation, beneficial invigorating the liver and kidney, vital essence replenishing and marrow benifiting, enhancing body immunity, nephropathy is had cure and the effect of rehabilitation, and is nontoxic to human body.
2, the present invention is without bitterness sense, taking convenience.
For showing the curative effect of medicine of the present invention, the present invention selects case through for many years clinical observation, and be a course for the treatment of January, day take 3 times, and each 1 bottle, nearly 500 examples that heal the sick, it is to cure that health returns to one's perfect health, and take a favorable turn as effectively.Cure rate reaches 85%, and total effective rate is 95%.
Model case is as follows:
1, Liu XX, the woman, 50 years old, people from Fei County, Shandong was engaged in agriculture.Readme was suffered from nephropathy more than 2 years, and the oral conventional Western medicine of being in is not felt any better.After testing: creatinine 126, blood urea nitrogen 14, urine protein 3+++, ERY 2++.Take 2 courses for the treatment of of medicine of the present invention, health takes a favorable turn, and drink fermented bean drink the every day of taking medicine between convalescence 1 time, and each 100-200ml paid a return visit rehabilitation after 2 years.
2, poplar XX, the woman, 32 years old, Linyi, Shandong tribal chief Zao Gou was engaged in agriculture.Readme suffers from nephropathy, after testing: creatinine 260, blood urea nitrogen 18, urine protein 3+++, ERY 3+++, take medicine of the present invention after 2 courses for the treatment of symptom begin to alleviate, fully recover after 5 courses for the treatment of, take medicine between convalescence and to drink 1 time fermented bean drink every day, each 100-200ml paid a return visit rehabilitation after 2 years.
3, woods XX, the woman, 30 years old, people from Fei County, Shandong was engaged in agriculture.Suffers from nephropathy, after testing: creatinine 400, blood urea nitrogen 25, urine protein 3+++, ERY 3+++.Take 1 course for the treatment of of medicine of the present invention, health take a favorable turn, and fully recovers after 7 courses for the treatment of, and drink fermented bean drink the every day of taking medicine between convalescence 1 time, and each 100-200ml paid a return visit rehabilitation after 2 years.
4, Liu XX, the man, 55 years old, Linyi, Shandong Nan Fang people was engaged in agriculture.Readme suffers from nephropathy, edema of the body hydrops.After testing: creatinine 140, blood urea nitrogen 16, urine protein 3+++, ERY 2++ takes medicine of the present invention and fully recovers after 3 courses for the treatment of; Take medicine between convalescence and to drink 1 time fermented bean drink every day, each 100-200ml; When edema hydrops symptom was arranged, every day, oral fast diaper 4-15 sheet was withdrawn weekly 2～3 days, the inactive Furosemide of hydrops disappearance.Pay a return visit rehabilitation after 2 years.
Annotate: during patient's medication treatment, must be careful in one's diet the suitable tonic such as beche-de-mer, physical training 30～60 minutes every days.
The specific embodiment takes by weighing raw material by following weight proportion: glucose 1000g, vitamin C 4.5g, shenqi pill 150g, kidney tonifying sheet 60g, artificial liquor for tonifying blood 500ml, Stigma Maydis 100g, 15 pieces in Fructus Jujubae, water 4.2Kg; Above-mentioned each component is made medicinal liquid according to a conventional method, finishes in the steps below successively:
1), pretreatment: slice lapping becomes powder with kidney tonifying with vitamin C, and shenqi pill is broken, and is for subsequent use;
2), stew soup: with Stigma Maydis, Fructus Jujubae and water boil 20 minutes, be cooled to 30 ℃ of filtrations, filtrate for later use;
3), the preparation medicinal liquid: with step 1) fine powder that grinds, broken shenqi pill and the glucose in the component, artificial liquor for tonifying blood, add step 2) filtrate in, mix homogeneously;
4), bottling: with step 3) medicinal liquid that makes, in the 100ml medicinal liquid bottle of the in advance sterilization of packing into, namely get medicine oral liquid of the present invention.
Annotate: medicine of the present invention be not suitable for because of diabetic complication cause the nephrotic; Front 4 days of urine examination stop drinking fermented bean drink, in order to avoid affect the accuracy of testing result.
The kidney tonifying sheet that uses is good nurse's kidney tonifying sheet; Shenqi pill is JINGUI SHENQI WAN.
Claims (1)
1. medicine for the treatment of nephritis is characterized in that it is made by following raw material components and proportioning: glucose 1000g, vitamin C 4.5g, JINGUI SHENQI WAN 150g, kidney tonifying sheet 60g, ferric ammonium citrate dimension B1 syrup 500ml, Stigma Maydis 100g, 15 pieces in Fructus Jujubae, water 4.2Kg; Above-mentioned each component is prepared successively in the steps below:
1), pretreatment: slice lapping becomes powder with kidney tonifying with vitamin C, and JINGUI SHENQI WAN is broken, and is for subsequent use;
2), stew soup: with Stigma Maydis, Fructus Jujubae and water boil 20 minutes, be cooled to 30 ℃ of filtrations, filtrate for later use;
3), the preparation medicinal liquid: with step 1) fine powder that grinds, broken JINGUI SHENQI WAN and the glucose in the component, ferric ammonium citrate dimension B1 syrup, add step 2) filtrate in, mix homogeneously;
4), bottling: with step 3) medicinal liquid that makes, in the 100ml medicinal liquid bottle of the in advance sterilization of packing into, get final product.
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| CN2009102601789A CN102106978B (en) | 2009-12-28 | 2009-12-28 | Medicament for treating nephritis |
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| CN2009102601789A CN102106978B (en) | 2009-12-28 | 2009-12-28 | Medicament for treating nephritis |
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| CN102106978B true CN102106978B (en) | 2013-02-13 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1562303A (en) * | 2004-04-02 | 2005-01-12 | 北京奥路特生物医药研发有限公司 | Soft capsules of guifu dihuang and preparation method |
| CN1631406A (en) * | 2003-12-24 | 2005-06-29 | 毛友昌 | Tablet formulation of 'Jingui Shenqi', its preparation and derivative formulation |
| CN101085255A (en) * | 2007-06-26 | 2007-12-12 | 北京艺信堂医药研究所 | Traditional Chinese medicine preparation for treating acute nephritis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631406A (en) * | 2003-12-24 | 2005-06-29 | 毛友昌 | Tablet formulation of 'Jingui Shenqi', its preparation and derivative formulation |
| CN1562303A (en) * | 2004-04-02 | 2005-01-12 | 北京奥路特生物医药研发有限公司 | Soft capsules of guifu dihuang and preparation method |
| CN101085255A (en) * | 2007-06-26 | 2007-12-12 | 北京艺信堂医药研究所 | Traditional Chinese medicine preparation for treating acute nephritis |
Non-Patent Citations (2)
| Title |
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| 朱生全.《慢性肾炎蛋白尿的中医治疗概述》.《陕西中医》.1983,第4卷(第3期),28-31. * |
| 杨广悦.《中医治疗IgA肾病的展望》.《河北中医》.2008,第30卷(第12期),1340-1342. * |
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