CN101066324A - Chinese medicine composition for treating erosion of mucous membrane of oral cavity during menstruation - Google Patents

Chinese medicine composition for treating erosion of mucous membrane of oral cavity during menstruation Download PDF

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CN101066324A
CN101066324A CN 200710100099 CN200710100099A CN101066324A CN 101066324 A CN101066324 A CN 101066324A CN 200710100099 CN200710100099 CN 200710100099 CN 200710100099 A CN200710100099 A CN 200710100099A CN 101066324 A CN101066324 A CN 101066324A
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parts
chinese medicine
radix
medicine composition
mucous membrane
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

The present invention provides Chinese medicine composition for treating erosion of mucous membrane of oral cavity during menstruation. The Chinese medicine composition is prepared with over ten kinds of Chinese medicinal materials, including skullcap root, gypsum, fried cape jasmine, figwort, etc. It has the functions of clearing away heat, purging fire, nourishing yin and relieving pain. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine composition has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

A kind of Chinese medicine composition for the treatment of erosion of the oral mucous membrane during menstruation
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of erosion of the oral mucous membrane during menstruation, is that a kind of erosion of the oral mucous membrane during menstruation for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Menopathy is meant cycle, the menstrual period and unusual through the amount generation of all menstruations, and follows menstrual cycle the significant discomfort symptom to occur, or the relevant a series of symptoms that occurred before and after menopause are a class disease of feature.Every value is through preceding or menstrual period, and aphtha of the mouth and tongue, rotten to the corn person claim " erosion of the oral mucous membrane during menstruation ".Pathogeny mainly is to accumulate in burning hot, and value menstrual phase chong channel is arrogant, and fire flaming up due to disorder of QI is burnt dispute and caused.Its typing has long-pending heat in the hyperactivity of fire caused by deficiency of YIN stomach function regulating.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of erosion of the oral mucous membrane during menstruation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Gypsum Fibrosum of 1.5~6 portions of Radix Scrophulariaes of Radix Scutellariae
1.0~4 parts of 1.0~4 parts of Fructus Gardeniae (parched) of 1.0~4 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
1.0~4 parts of 1.0~4 parts of Radix Rehmanniae of 1.0~4 portions of Radix Paeoniae Albas of Flos Chrysanthemi
0.1~2 part of 0.1~2 part of Cortex Moutan of 0.1~2 portion of Rhizoma Coptidis of Radix Paeoniae Rubra
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Gypsum Fibrosum of 2.5~3.5 portions of Radix Scrophulariaes of Radix Scutellariae
1.5~2.5 parts of 1.5~2.5 parts of Fructus Gardeniae (parched) of 1.5~2.5 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae of 1.5~2.5 portions of Radix Paeoniae Albas of Flos Chrysanthemi
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 0.5~1.5 portion of Rhizoma Coptidis of Radix Paeoniae Rubra
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Gypsum Fibrosum of 3 portions of Radix Scrophulariaes of Radix Scutellariae
2 parts of 2 parts of Fructus Gardeniae (parched) of 2 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
2 parts of 2 parts of Radix Rehmanniae of 2 portions of Radix Paeoniae Albas of Flos Chrysanthemi
1 part of 1 part of Cortex Moutan of 1 portion of Rhizoma Coptidis of Radix Paeoniae Rubra
Drug action mechanism among the present invention is as follows:
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Gypsum Fibrosum property of medicine suffering, sweet, cold.Return stomach, lung meridian.Has clearing away heat-fire, the effect that relieving restlessness is quenched the thirst.Can treat the calentura hyperpyrexia, excessive thirst, unconsciousness and delirium is gone mad, and sends out speckle, dyspnea and cough due to lung-heat, heatstroke, stomach-fire headache, toothache, aphtha of the mouth and tongue.Forge then promoting tissue regeneration and ulcer healing, control ulcer sores and burst and not close up burn etc.(the 826th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The little hardship of the Herba Artemisiae Scopariae property of medicine, little suffering are slightly cold.Return spleen, stomach, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Can treat jaundice, dysuria, eczema pruritus etc.(the 2146th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Forsythiae property of medicine hardship is slightly cold.Return lung, the heart, gallbladder meridian.Has heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds.Can treat anemopyretic cold, epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat etc.(the 1554th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Flos Chrysanthemi property of medicine is sweet, bitter, is slightly cold.Return lung, Liver Channel.Have wind and heat dispersing, suppressing the hyperactive liver makes eye bright, the effect of removing toxic substances and promoting subsidence of swelling.Can treat affection due to external wind and heat or pathogenic wind-warm from the beginning of, fever and headache, dizzy, conjunctival congestion and swelling pain, furuncle swelling toxin etc.(the 2900th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Cure mainly the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, the furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Scutellariae, Radix Scrophulariae and Gypsum Fibrosum; With Herba Artemisiae Scopariae, Fructus Forsythiae, Fructus Gardeniae (parched), Flos Chrysanthemi, the Radix Paeoniae Alba and Radix Rehmanniae is ministerial drug; With Radix Paeoniae Rubra, Rhizoma Coptidis and Cortex Moutan is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat-fire, yin nourishing analgesic effect.The treatment erosion of the oral mucous membrane during menstruation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment erosion of the oral mucous membrane during menstruation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat erosion of the oral mucous membrane during menstruation, and the prevention of erosion of the oral mucous membrane during menstruation is also had good effect, and the treatment erosion of the oral mucous membrane during menstruation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment erosion of the oral mucous membrane during menstruation; Treatment erosion of the oral mucous membrane during menstruation patient 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 43.75%, and 7 examples that take a turn for the better account for 43.75%, and more 2 examples do not account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Gypsum Fibrosum of 3 portions of Radix Scrophulariaes of Radix Scutellariae
2 parts of 2 parts of Fructus Gardeniae (parched) of 2 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
2 parts of 2 parts of Radix Rehmanniae of 2 portions of Radix Paeoniae Albas of Flos Chrysanthemi
1 part of 1 part of Cortex Moutan of 1 portion of Rhizoma Coptidis of Radix Paeoniae Rubra
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment erosion of the oral mucous membrane during menstruation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of erosion of the oral mucous membrane during menstruation is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Gypsum Fibrosum of 1.5~6 portions of Radix Scrophulariaes of Radix Scutellariae
1.0~4 parts of 1.0~4 parts of Fructus Gardeniae (parched) of 1.0~4 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
1.0~4 parts of 1.0~4 parts of Radix Rehmanniae of 1.0~4 portions of Radix Paeoniae Albas of Flos Chrysanthemi
0.1~2 part of 0.1~2 part of Cortex Moutan of 0.1~2 portion of Rhizoma Coptidis of Radix Paeoniae Rubra.
2, a kind of Chinese medicine composition for the treatment of erosion of the oral mucous membrane during menstruation according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Gypsum Fibrosum of 2.5~3.5 portions of Radix Scrophulariaes of Radix Scutellariae
1.5~2.5 parts of 1.5~2.5 parts of Fructus Gardeniae (parched) of 1.5~2.5 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae of 1.5~2.5 portions of Radix Paeoniae Albas of Flos Chrysanthemi
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 0.5~1.5 portion of Rhizoma Coptidis of Radix Paeoniae Rubra.
3, a kind of Chinese medicine composition for the treatment of erosion of the oral mucous membrane during menstruation according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Gypsum Fibrosum of 3 portions of Radix Scrophulariaes of Radix Scutellariae
2 parts of 2 parts of Fructus Gardeniae (parched) of 2 parts of Fructus Forsythiaes of Herba Artemisiae Scopariae
2 parts of 2 parts of Radix Rehmanniae of 2 portions of Radix Paeoniae Albas of Flos Chrysanthemi
1 part of 1 part of Cortex Moutan of 1 portion of Rhizoma Coptidis of Radix Paeoniae Rubra.
CN 200710100099 2007-06-05 2007-06-05 Chinese medicine composition for treating erosion of mucous membrane of oral cavity during menstruation Pending CN101066324A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599242A (en) * 2013-11-20 2014-02-26 安徽宝芝堂药业有限公司 Traditional Chinese medicine composition for treating aphthous stomatitis
CN104147233A (en) * 2014-08-29 2014-11-19 张连生 Externally used medicine for treating recurrent stomatitis
CN104225291A (en) * 2014-07-24 2014-12-24 烟台瑞智生物医药科技有限公司 Traditional Chinese medicine for treating intermenstrual aphthous stomatitis due to yin-deficiency and fire-hyperactivity syndromes
CN106109852A (en) * 2016-08-05 2016-11-16 王彬 A kind of Chinese medicine preparation treating type of hyperactivity of fire caused by deficiency of YIN erosion of the oral mucous membrane during menstruation
CN106110162A (en) * 2016-08-05 2016-11-16 王彬 A kind of Chinese medicine preparation treating gastric heat fumigation type erosion of the oral mucous membrane during menstruation
CN107581423A (en) * 2017-10-17 2018-01-16 张家红 It is a kind of to treat drink of aphtha and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599242A (en) * 2013-11-20 2014-02-26 安徽宝芝堂药业有限公司 Traditional Chinese medicine composition for treating aphthous stomatitis
CN104225291A (en) * 2014-07-24 2014-12-24 烟台瑞智生物医药科技有限公司 Traditional Chinese medicine for treating intermenstrual aphthous stomatitis due to yin-deficiency and fire-hyperactivity syndromes
CN104147233A (en) * 2014-08-29 2014-11-19 张连生 Externally used medicine for treating recurrent stomatitis
CN104147233B (en) * 2014-08-29 2017-01-25 张连生 Externally used medicine for treating recurrent stomatitis
CN106109852A (en) * 2016-08-05 2016-11-16 王彬 A kind of Chinese medicine preparation treating type of hyperactivity of fire caused by deficiency of YIN erosion of the oral mucous membrane during menstruation
CN106110162A (en) * 2016-08-05 2016-11-16 王彬 A kind of Chinese medicine preparation treating gastric heat fumigation type erosion of the oral mucous membrane during menstruation
CN107581423A (en) * 2017-10-17 2018-01-16 张家红 It is a kind of to treat drink of aphtha and preparation method thereof

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Open date: 20071107