CN101095856A - Chinese traditional medicine for treating anaphylactoid purpura nephritis - Google Patents
Chinese traditional medicine for treating anaphylactoid purpura nephritis Download PDFInfo
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- CN101095856A CN101095856A CNA2007101183283A CN200710118328A CN101095856A CN 101095856 A CN101095856 A CN 101095856A CN A2007101183283 A CNA2007101183283 A CN A2007101183283A CN 200710118328 A CN200710118328 A CN 200710118328A CN 101095856 A CN101095856 A CN 101095856A
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Abstract
The invention relates to a Chinese medicinal composition for treating allergic purpura nephritis, which is prepared from more than ten kinds of Chinese medicinal herbs including buffalo horn, dried rehmannia root, field thistle and bark of peony root. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of anaphy lactoid purpura nephritis, is that a kind of anaphy lactoid purpura nephritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Anaphylactoid purpura is to be the syndrome of feature with skin purpura, gastroenteritis haemorrhagica, arthritis and kidney damage, is a kind of general polyangitis relevant with immunity.The renal damage that anaphylactoid purpura causes claims anaphy lactoid purpura nephritis.The clinical symptoms weight differs, from simple urine examination unusually to the typical acute nephritic syndrome, nephrotic syndrome even renal failure.Hematuria (under naked eyes or the mirror) is its common performance, and Most patients is optimum, self-limited course is more than fully recovering in several weeks.But outbreak repeatedly or delay several months, several years person are arranged also.About 50% patient's course of disease is shown effect repeatedly.The order of severity of pathological change is depended in prognosis.The anaphy lactoid purpura nephritis sickness rate accounts for 20%～100% of patients with anaphylactoid purpura, domesticly is reported in 30%～50%, abroad have with the kidney biopsy be diagnostic criteria then sickness rate up to more than 90%.Any age of primary disease all can fall ill, and is more common in child and teenager, with 6～13 years old for the highest, gender's ratio is 1.5～3: 1, betides cold season well.Henoch Schonlein purpura nephritis belongs to Chinese medicine " hematuria ", " hematohidrosis ", " edema " sick categories such as " arthromyodynias ".The clinical manifestation of primary disease is: erythra, joint symptom, gastrointestinal symptom and other symptom.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as pathogenic wind toxic is invaded, the high Sheng of pyretic toxicity, the heat in blood of suffering from a deficiency of the kidney, asthenia of pulmonosplenic qi, deficiency of both QI and YIN, deficiency of spleen-YANG and kidneyYANG clinically outward, obtains very good effect.The traditional Chinese medical science and therapy of combining Chinese and Western medicine henoch Schonlein purpura nephritis have been received curative effect preferably in recent years, have represented fine prospect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of anaphy lactoid purpura nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1～2 part of 1.5～6 parts of Pollen Tyjphae of 1.5～6 portions of Herba Cirsiis of Cornu Bubali
0.1～2 part of 1.0～4 portions of Radix Scrophulariae of 1.5～6 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.1～2 part of 1.0～4 portions of Herba Lophatheri of 1.0～4 parts of Talcums of Cortex Moutan
0.1～2 part of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
The weight proportion of each raw material of optimization formula of the present invention is:
0.5～1.5 part of 2.5～3.5 parts of Pollen Tyjphae of 2.5～3.5 portions of Herba Cirsiis of Cornu Bubali
0.5～1.5 part of 1.5～2.5 portions of Radix Scrophulariae of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 portions of Herba Lophatheri of 1.5～2.5 parts of Talcums of Cortex Moutan
0.5～1.5 part of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 3 parts of Pollen Tyjphae of 3 portions of Herba Cirsiis of Cornu Bubali
1 part of 2 portions of Radix Scrophulariae of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 portions of Herba Lophatheri of 2 parts of Talcums of Cortex Moutan
1 part of 2 parts of Radix Ophiopogonis of 2 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
Drug action mechanism among the present invention is as follows:
Cornu Bubali property of medicine hardship, salty, cold.Has heat clearing away, detoxifcation, removing heat from blood, the effect of arresting convulsion.Can treat the calentura headache, unconsciousness due to high fever; Send out the speckle dermexanthesis, haematemesis, epistaxis, stagnant heat jaundice, infantile convulsion and laryngopharynx swelling and pain, aphtha of the mouth and tongue etc.(the 732nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Sweet, the little hardship of the Herba Cirsii property of medicine, cold.Return liver, spleen channel.Has cooling blood for hemostasis, the effect of removing toxic substances and promoting subsidence of swelling.Can treat hematuria, stranguria with blood, hemoptysis is spitted blood, and epistaxis is had blood in stool, dysentery, metrorrhagia and metrostaxis, traumatic hemorrhage, swollen ulcer drug etc.(the 331st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Talcum property of medicine is sweet, light, and is cold.Return bladder, stomach warp.Has inducing diuresis for treating stranguria syndrome, the effect of clearing away summer-heat.Can treat damp-heat in the urinary bladder, dysuria, urine drenches puckery pain, edema, the summer-heat excessive thirst is had loose bowels, eczema, eczema, miliaria etc.(the 3387th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Pollen Tyjphae property of medicine, flat.Return liver, the heart, spleen channel.Has hemostasis, blood stasis dispelling, diuretic effect.Can treat haematemesis, spitting of blood, epistaxis, dysentery is had blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, puerperal stasis of blood pain, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, leukorrhagia, congenital deformity of the tongue, aphtha, ear, uncontrolled urination are itched etc.(the 3423rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Lophatheri property of medicine is sweet, light, and is cold.GUIXIN, lung, stomach warp.Have clearing heat and relieving fidgetness, promote the production of body fluid, the diuretic effect.Can treat the calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, oliguria with reddish urine, erosion of the oral mucosa tongue boil etc.(the 1240th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cornu Bubali, Radix Rehmanniae and Herba Cirsii; With Fructus Gardeniae (parched), Cortex Moutan, Radix Paeoniae Rubra, Talcum, Radix Scutellariae, Radix Scrophulariae and Radix Ophiopogonis is ministerial drug; With Pollen Tyjphae and Herba Lophatheri is adjuvant.All medicines are harmonious, tool cooling blood for hemostasis altogether, dissipating rashes antidotal effect.The treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment anaphy lactoid purpura nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat anaphy lactoid purpura nephritis, and the prevention of anaphy lactoid purpura nephritis is also had good effect, and the treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment anaphy lactoid purpura nephritis; Treatment anaphy lactoid purpura nephritis patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 40%, and 12 examples that take a turn for the better account for 48%, and invalid 3 examples account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 3 parts of Pollen Tyjphae of 3 portions of Herba Cirsiis of Cornu Bubali
1 part of 2 portions of Radix Scrophulariae of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 portions of Herba Lophatheri of 2 parts of Talcums of Cortex Moutan
1 part of 2 parts of Radix Ophiopogonis of 2 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment anaphy lactoid purpura nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis is characterized in that it is made by the following weight proportion raw material:
0.1～2 part of 1.5～6 parts of Pollen Tyjphae of 1.5～6 portions of Herba Cirsiis of Cornu Bubali
0.1～2 part of 1.0～4 portions of Radix Scrophulariae of 1.5～6 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.1～2 part of 1.0～4 portions of Herba Lophatheri of 1.0～4 parts of Talcums of Cortex Moutan
0.1～2 part of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
2, a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
0.5～1.5 part of 2.5～3.5 parts of Pollen Tyjphae of 2.5～3.5 portions of Herba Cirsiis of Cornu Bubali
0.5～1.5 part of 1.5～2.5 portions of Radix Scrophulariae of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Rehmanniae
0.5～1.5 part of 1.5～2.5 portions of Herba Lophatheri of 1.5～2.5 parts of Talcums of Cortex Moutan
0.5～1.5 part of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
3, a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
1 part of 3 parts of Pollen Tyjphae of 3 portions of Herba Cirsiis of Cornu Bubali
1 part of 2 portions of Radix Scrophulariae of 3 parts of Radix Paeoniae Rubra of Radix Rehmanniae
1 part of 2 portions of Herba Lophatheri of 2 parts of Talcums of Cortex Moutan
1 part of 2 parts of Radix Ophiopogonis of 2 parts of Radix Scutellariaes of Fructus Gardeniae (parched).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183283A CN101095856A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating anaphylactoid purpura nephritis |
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| CNA2007101183283A CN101095856A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating anaphylactoid purpura nephritis |
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| CNA2007101183283A Pending CN101095856A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating anaphylactoid purpura nephritis |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301428B (en) * | 2008-06-03 | 2011-09-21 | 陈德顺 | Oral Chinese medicine for treating pyelonephritis with hematuria |
| CN102940734A (en) * | 2012-10-10 | 2013-02-27 | 肥西县中医院 | Traditional Chinese medicine for treating purpura |
| CN103432429A (en) * | 2013-07-26 | 2013-12-11 | 张启锐 | Traditional Chinese medicine used for treating chronic nephritis and preparation method thereof |
| CN103495113A (en) * | 2013-09-09 | 2014-01-08 | 徐如阳 | Traditional Chinese medicine composition for treating henoch-schonleinpurpura |
| CN103610827A (en) * | 2013-12-08 | 2014-03-05 | 朱英 | Medicine for treating anaphylactic purpura nephritis and preparation method thereof |
| CN104510942A (en) * | 2015-01-14 | 2015-04-15 | 刘小芳 | Traditional Chinese medicine for treating allergic purpura |
| CN109157585A (en) * | 2018-10-10 | 2019-01-08 | 河南中医药大学 | A kind of Chinese medicine for treating children with Henoch-Schonlein purpura nephritis blood-heat bleeding card |
-
2007
- 2007-07-05 CN CNA2007101183283A patent/CN101095856A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301428B (en) * | 2008-06-03 | 2011-09-21 | 陈德顺 | Oral Chinese medicine for treating pyelonephritis with hematuria |
| CN102940734A (en) * | 2012-10-10 | 2013-02-27 | 肥西县中医院 | Traditional Chinese medicine for treating purpura |
| CN103432429A (en) * | 2013-07-26 | 2013-12-11 | 张启锐 | Traditional Chinese medicine used for treating chronic nephritis and preparation method thereof |
| CN103495113A (en) * | 2013-09-09 | 2014-01-08 | 徐如阳 | Traditional Chinese medicine composition for treating henoch-schonleinpurpura |
| CN103495113B (en) * | 2013-09-09 | 2015-04-22 | 徐如阳 | Traditional Chinese medicine composition for treating henoch-schonleinpurpura |
| CN103610827A (en) * | 2013-12-08 | 2014-03-05 | 朱英 | Medicine for treating anaphylactic purpura nephritis and preparation method thereof |
| CN103610827B (en) * | 2013-12-08 | 2015-06-24 | 朱英 | Medicine for treating anaphylactic purpura nephritis and preparation method thereof |
| CN104510942A (en) * | 2015-01-14 | 2015-04-15 | 刘小芳 | Traditional Chinese medicine for treating allergic purpura |
| CN109157585A (en) * | 2018-10-10 | 2019-01-08 | 河南中医药大学 | A kind of Chinese medicine for treating children with Henoch-Schonlein purpura nephritis blood-heat bleeding card |
| CN109157585B (en) * | 2018-10-10 | 2020-12-22 | 河南中医药大学 | Traditional Chinese medicine for treating blood-heat bleeding syndrome of purpuric nephritis in children |
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Open date: 20080102 |