CN101085207A - Traditional Chinese medicine preparation for treating hyperthyroidism - Google Patents

Traditional Chinese medicine preparation for treating hyperthyroidism Download PDF

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Publication number
CN101085207A
CN101085207A CNA200710117850XA CN200710117850A CN101085207A CN 101085207 A CN101085207 A CN 101085207A CN A200710117850X A CNA200710117850X A CN A200710117850XA CN 200710117850 A CN200710117850 A CN 200710117850A CN 101085207 A CN101085207 A CN 101085207A
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parts
chinese medicine
rhizoma
radix
portions
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CNA200710117850XA
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA200710117850XA priority Critical patent/CN101085207A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating hyperthyroidism, which is prepared from more than ten kinds of Chinese medicinal herbs including anemarrhena rhizome, radish seeds and yellow-corktree bark.

Description

A kind of Chinese medicine preparation of treatment hyperthyroidism
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of hyperthyroidism, is that the treatment hyperthyroidism is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Hyperthyroidism (abbreviation hyperthyroidism) is meant that the thyroxin that is caused by multiple reason increases, and acts on the histoorgan of whole body, causes system's irritabilitys such as nerve, circulation, digestion of body to increase and hypermetabolism is the general name of the disease of main performance.It is the common big class disease of hormonal system.The primary disease onset is slow, and direct stimulation is major incentive as fear, sadness, rage etc.The performance of model case hypermetabolism disease group, high neural excitation, goiter and oculopathy several respects is all more obvious; The state of an illness is obscured with neurosis mutually than the lighter is easy.The patient who has serves as main performance with some characteristic symptom such as expophthalmos, cachexia or myopathy etc. often.Performance old and child patient often is not true to type.In recent years, owing to improving constantly of diagnostic level, the light disease and the patient that is not true to type also can find early.Hyperthyroidism belongs to categories such as Chinese medicine " goiter ", " melancholia ", " asthenia ".Diffuse goiter companion hyperthyroidism is an autoimmune disease that can involve each system of whole body, and its treatment has antithyroid drug, subtotal thyroidectomy, radioiodine therapy etc.The Drug therapy relapse rate is higher, accounts for 40%~50%.If malpractice or recurrence are not repeatedly touchingly healed, can cause serious hyperthyroid heart disease, even heart failure, serious arrhythmia, hyperthyroidism periodic paralysis, patient disability be can make and quality of life, very then threat to life influenced.Hyperthyroidism crisis is a critical emergency case of hyperthyroidism, and mortality rate reaches 50%~70%, so answer active prevention, diagnosis is in time rescued with all strength, to save patient's life.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of hyperthyroidism.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the raw material of following weight optimum ratio:
1.5~6 parts of 1.5~6 parts of Concha Ostreae of 1.5~6 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
1.0~4 parts of 1.0~4 parts of Semen Raphanis of 1.0~4 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
1.0~4 parts of 1.0~4 parts of Radix Ophiopogonis of 1.0~4 portions of Radix Scrophulariaes of Spica Prunellae
0.1~1 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.1~1 part of 0.1~2 part of Rhizoma Dioscoreae Bulbiferae of 0.1~2 part of Semen Vaccariae of Cortex Moutan
The best proportioning of the weight of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Concha Ostreae of 2.5~3.5 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
1.5~2.5 parts of 1.5~2.5 parts of Semen Raphanis of 1.5~2.5 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
1.5~2.5 parts of 1.5~2.5 parts of Radix Ophiopogonis of 1.5~2.5 portions of Radix Scrophulariaes of Spica Prunellae
0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.3~0.7 part of 0.5~1.5 part of Rhizoma Dioscoreae Bulbiferae of 0.5~1.5 part of Semen Vaccariae of Cortex Moutan
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Concha Ostreae of 3 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
2 parts of 2 parts of Semen Raphanis of 2 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Radix Scrophulariaes of Spica Prunellae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Rhizoma Dioscoreae Bulbiferae of 1 part of Semen Vaccariae of Cortex Moutan
Drug action mechanism among the present invention is as follows:
Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter , mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever , Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Spica Prunellae property of medicine hardship, suffering, cold.Return liver, gallbladder meridian.Has liver heat removing and eyesight improving, the effect of powder detoxifcation.Can treat the conjunctival congestion photophobia, ophthalmalgia, it is dizzy to have a headache, tinnitus, scrofula goiter, acute mastitis mumps, carbuncle furuncle and phyma poison, acute and chronic hepatitis, hypertension etc.(the 2562nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Raphani property of medicine suffering, sweet, flat.Return spleen, stomach, lung, large intestine channel.Has dyspepsia and intestinal stasis relieving, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy behind the dysentery, cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Carapax Et Plastrum Testudinis property of medicine is salty, sweet, is slightly cold.Return liver, kidney, heart channel.Has nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, the effect of consolidating channel for hemostasis.Can treat deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and wriggling of the limbs, a little less than the muscles and bones flaccidity, children's's halogen door does not conform to, and the palpitation with fear insomnia is forgetful, menorrhagia, metrorrhagia and metrostaxis.(the 1608th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Bulbus Fritillariae Thunbergii property of medicine hardship, cold.Return lung, heart channel.Has removing heat-phlegm, sending down the abnormal ascending QI cough-relieving, the effect of mass dissipating and swelling eliminating.Can treat wind heat or phlegm-heat cough, lung abscess vomiting pus, scrofula goiter, sore and toxic etc.(the 2711st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatism pyretic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Vaccariae property of medicine hardship, flat.Return liver, stomach warp.Has promoting blood circulation to restore menstrual flow, the effect of stimulating milk secretion eliminating carbuncle.Can treat women's abdominal pain during menstruation, amenorrhea, galactostasis, acute mastitis, carbuncle etc.(the 426th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Dioscoreae Bulbiferae property of medicine hardship, cold, mild toxicity.Return lung, Liver Channel.Has the eliminating stagnation wart that disappears, heat-clearing and toxic substances removing, the effect of cooling blood for hemostasis.Can treat goiter, sore throat, carbuncle sore tumefacting virus, venom, tumor is spitted blood, epistaxis, spitting of blood, pertussis, lung-heat cough with asthma etc.(the 2858th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Rhizoma Anemarrhenae, Radix Rehmanniae and Concha Ostreae; With Cortex Phellodendri, Rhizoma Dioscoreae, Semen Raphani, Spica Prunellae, Radix Scrophulariae, Radix Ophiopogonis, Carapax Et Plastrum Testudinis, Rhizoma Dioscoreae Bulbiferae and Rhizoma Pinelliae Preparatum is ministerial drug; With Bulbus Fritillariae Thunbergii, Cortex Moutan and Semen Vaccariae is adjuvant.All medicines are harmonious, altogether the effect of tool nourishing YIN to lower pathogenic fire, clearing away phlegm eliminating stagnation.The treatment hyperthyroidism has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment hyperthyroidism of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat hyperthyroidism, and the prevention of hyperthyroidism is also had good effect, and the treatment hyperthyroidism has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment hyperthyroidism; Treatment hyperthyroid patient 13 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 46.15%, and 6 examples that take a turn for the better account for 46.15%, and more 1 example does not account for 7.69%, and total effective rate reaches 92.3%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Concha Ostreae of 3 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
2 parts of 2 parts of Semen Raphanis of 2 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Radix Scrophulariaes of Spica Prunellae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Rhizoma Dioscoreae Bulbiferae of 1 part of Semen Vaccariae of Cortex Moutan.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment hyperthyroidism that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation of treatment hyperthyroidism is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Concha Ostreae of 1.5~6 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
1.0~4 parts of 1.0~4 parts of Semen Raphanis of 1.0~4 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
1.0~4 parts of 1.0~4 parts of Radix Ophiopogonis of 1.0~4 portions of Radix Scrophulariaes of Spica Prunellae
0.1~1 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.1~1 part of 0.1~2 part of Rhizoma Dioscoreae Bulbiferae of 0.1~2 part of Semen Vaccariae of Cortex Moutan.
2, a kind of Chinese medicine preparation of treatment hyperthyroidism according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Concha Ostreae of 2.5~3.5 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
1.5~2.5 parts of 1.5~2.5 parts of Semen Raphanis of 1.5~2.5 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
1.5~2.5 parts of 1.5~2.5 parts of Radix Ophiopogonis of 1.5~2.5 portions of Radix Scrophulariaes of Spica Prunellae
0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.3~0.7 part of 0.5~1.5 part of Rhizoma Dioscoreae Bulbiferae of 0.5~1.5 part of Semen Vaccariae of Cortex Moutan.
3, a kind of Chinese medicine preparation of treatment hyperthyroidism according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Concha Ostreae of 3 parts of Radix Rehmanniae of the Rhizoma Anemarrhenae
2 parts of 2 parts of Semen Raphanis of 2 portions of Rhizoma Dioscoreaes of Cortex Phellodendri
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Radix Scrophulariaes of Spica Prunellae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Bulbus Fritillariae Thunbergiis of Carapax Et Plastrum Testudinis
0.5 part of 1 part of Rhizoma Dioscoreae Bulbiferae of 1 part of Semen Vaccariae of Cortex Moutan.
CNA200710117850XA 2007-06-26 2007-06-26 Traditional Chinese medicine preparation for treating hyperthyroidism Pending CN101085207A (en)

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Application Number Priority Date Filing Date Title
CNA200710117850XA CN101085207A (en) 2007-06-26 2007-06-26 Traditional Chinese medicine preparation for treating hyperthyroidism

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102441110A (en) * 2011-12-01 2012-05-09 李金金 Traditional Chinese medicinal composition for auxiliary treatment of hyperthyroidism
CN101890125B (en) * 2009-05-21 2012-05-30 中国中医科学院广安门医院 Medicament for treating hyperthyroidism and preparation method thereof
CN104383226A (en) * 2014-12-11 2015-03-04 谭清平 Traditional Chinese medicine preparation for treating hyperthyroidism

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890125B (en) * 2009-05-21 2012-05-30 中国中医科学院广安门医院 Medicament for treating hyperthyroidism and preparation method thereof
CN102441110A (en) * 2011-12-01 2012-05-09 李金金 Traditional Chinese medicinal composition for auxiliary treatment of hyperthyroidism
CN102441110B (en) * 2011-12-01 2013-08-21 李金金 Traditional Chinese medicinal composition for auxiliary treatment of hyperthyroidism
CN104383226A (en) * 2014-12-11 2015-03-04 谭清平 Traditional Chinese medicine preparation for treating hyperthyroidism

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Open date: 20071212