CN101085186A - Traditional Chinese medicine for treating chronic renal failure retention enema - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for retention enema during treating chronic renal failure which is prepared from more than ten kinds of Chinese medicinal herbs including poria cocos, rhubarb horsetails, bone fat and motherwort fruit.

Description

A kind of Chinese medicine of treatment chronic renal failure retention enema

Technical field

The present invention relates to treat a kind of Chinese medicine of chronic renal failure retention enema, is that a kind of chronic kidney hypofunction for the treatment of is the Chinese medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Chronic renal failure (chronic kidney hypofunction) is because the result of kidney damage that a variety of causes causes and the deterioration of carrying out property, body is at the excretion metabolism product, regulate water, electrolyte, acid-base balance, and the clinical syndrome that gets muddled of aspects such as the generation of some endocrine activity material and deactivation.Chronic kidney hypofunction belongs to categories such as " difficulty in urination ", " obstruction and rejection ", " edema ", " asthenia " in the traditional Chinese medical science.Chronic kidney hypofunction can be by multiple kidney disease development such as edema, stranguria, hematuria.The traditional Chinese medical science thinks that with the passing of time various nephropathy, undermine each function, and based on the spleen damage of suffering from a deficiency of the kidney, the state of an illness progressively develops and aggravates disease, and causes the positive deficiency of vital energy to decline at last, and turbid pathogen, blood stasis are stopped up the kidney network that stagnates, cause kidney to lose out entire function, the retention of turbid damp uremic is in body, and the initiation primary disease.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as spleen deficiency of kidney-QI, deficiency of spleen-YANG and kidneyYANG, the hepatic and renal YIN deficiency, deficiency of both YIN and YANG clinically, obtains very good effect.The research of Chinese medicine chronic kidney hypofunction has had bigger progress.Theoretical side, vital QI being weakened and pathogen being violent, the pathogenic characteristic of carrying throughout must be known together.Differential diagnosis in tcm opinion control Chinese medicine decoction in the delaying chronic kidney hypofunction progress, improve clinical symptoms and cooperate hemodialysis, reduce the dialysis complication, improve dialysis patient life quality aspect and all obtained certain effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine for the treatment of chronic renal failure retention enema.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Herba Leonuris of 1.5～6 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

0.1～2 part of 1.0～4 parts of Fructus Kochiae of 1.5～6 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

0.1～2 part of 1.0～4 parts of Bulbus Fritillariae Thunbergii of 1.5～6 parts of Radix Morindae Officinaliss of Concha Ostreae

0.1～2 part of 1.0～4 parts of Radix Sophorae Flavescentis of 1.0～4 parts of Fructus Psoraleaes of Herba Taraxaci.

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 parts of Herba Leonuris of 2.5～3.5 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

0.5～1.5 part of 1.5～2.5 parts of Fructus Kochiae of 2.5～3.5 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

0.5～1.5 part of 1.5～2.5 parts of Bulbus Fritillariae Thunbergii of 2.5～3.5 parts of Radix Morindae Officinaliss of Concha Ostreae

0.5～1.5 part of 1.5～2.5 parts of Radix Sophorae Flavescentis of 1.5～2.5 parts of Fructus Psoraleaes of Herba Taraxaci.

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 2 parts of Herba Leonuris of 3 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

1 part of 2 parts of Fructus Kochiae of 3 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

1 part of 2 parts of Bulbus Fritillariae Thunbergii of 3 parts of Radix Morindae Officinaliss of Concha Ostreae

1 part of 2 parts of Radix Sophorae Flavescentis of 2 parts of Fructus Psoraleaes of Herba Taraxaci.

Drug action mechanism among the present invention is as follows:

The Rhizoma Smilacis Glabrae property of medicine is sweet, light, and is flat.Return liver,kidney,spleen, stomach warp.Have removing damp-heat, let out turbid detoxifcation, the effect of easing joint movement.Can treat syphilis, stranguria with turbid discharge is had loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism etc.(the 124th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Taraxaci property of medicine hardship, sweet, cold.Return liver, stomach warp.Has heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.Can treat acute mastitis, lung abscess, acute appendicitis, mumps, scrofula, furuncle carbuncle toxin, conjunctival congestion and swelling pain, cat fever, cough, laryngopharynx swelling and pain, gastritis, enteritis, dysentery, hepatitis, cholecystitis, urinary tract infection, snake bite and insect sting, burn and scald etc.(the 3427th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Psoraleae property of medicine suffering, hardship, temperature.Return kidney, spleen channel.Has reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal effect.Can treat the deficiency and coldness lumbago, sexual impotence spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, dyspnea due to deficiency, vitiligo, alopecia areata, psoriasis etc.(the 1647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Kochiae property of medicine hardship, cold.Return kidney, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of dispelling wind for relieving itching.Can treat dysuria, stranguria with turbid discharge, leukorrhagia, dysentery, rubella, eczema, scabies, skin pruritus, sore etc.(the 1137th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Bulbus Fritillariae Thunbergii property of medicine hardship, cold.Return lung, heart channel.Has removing heat-phlegm, sending down the abnormal ascending QI cough-relieving, the effect of mass dissipating and swelling eliminating.Can treat wind heat or phlegm-heat cough, lung abscess vomiting pus, scrofula goiter, sore and toxic etc.(the 2711st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, people's intestinal warp.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Smilacis Glabrae, Radix Et Rhizoma Rhei and Concha Ostreae; With Herba Taraxaci, Radix Angelicae Sinensis, Cortex Phellodendri, Radix Morindae Officinalis, Fructus Psoraleae and Herba Leonuri is ministerial drug; With the Fructus Kochiae, Bulbus Fritillariae Thunbergii and Radix Sophorae Flavescentis is adjuvant.All medicines are harmonious, and the tool temperature is held up Yuanyang, the effect that tonification is Kidney-Yin altogether.The treatment chronic kidney hypofunction has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment chronic kidney hypofunction of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat chronic kidney hypofunction, and the prevention of chronic kidney hypofunction is also had good effect, and the treatment chronic kidney hypofunction has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chronic kidney hypofunction; Treatment chronic kidney hypofunction patient 17 examples.The embodiment decoction, each 1 bag, coloclysis behind the defecation keeps after 10 1 30 minutes and discharges.Be embodied as good before sleeping to secondary in one day one.One month is a course of treatment, use continuously three the course of treatment observe the curative effect.Produce effects 7 examples account for 41.18%, and effective 8 examples account for 47.06%, and invalid 2 examples account for 11.76%, and total effective rate reaches 88.24%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 2 parts of Herba Leonuris of 3 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

1 part of 2 parts of Fructus Kochiae of 3 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

1 part of 2 parts of Bulbus Fritillariae Thunbergii of 3 parts of Radix Morindae Officinaliss of Concha Ostreae

1 part of 2 parts of Radix Sophorae Flavescentis of 2 parts of Fructus Psoraleaes of Herba Taraxaci.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chronic kidney hypofunction that the present invention makes is that plastic packaging is packed, every bag of 210ml, retention enema, one time one bag, every day one is to secondary.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine of treatment chronic renal failure retention enema is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Herba Leonuris of 1.5～6 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

0.1～2 part of 1.0～4 parts of Fructus Kochiae of 1.5～6 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

0.1～2 part of 1.0～4 parts of Bulbus Fritillariae Thunbergii of 1.5～6 parts of Radix Morindae Officinaliss of Concha Ostreae

0.1～2 part of 1.0～4 parts of Radix Sophorae Flavescentis of 1.0～4 parts of Fructus Psoraleaes of Herba Taraxaci.

2, a kind of Chinese medicine of treatment chronic renal failure retention enema according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 1.5～2.5 parts of Herba Leonuris of 2.5～3.5 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

0.5～1.5 part of 1.5～2.5 parts of Fructus Kochiae of 2.5～3.5 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

0.5～1.5 part of 1.5～2.5 parts of Bulbus Fritillariae Thunbergii of 2.5～3.5 parts of Radix Morindae Officinaliss of Concha Ostreae

0.5～1.5 part of 1.5～2.5 parts of Radix Sophorae Flavescentis of 1.5～2.5 parts of Fructus Psoraleaes of Herba Taraxaci.

3, a kind of Chinese medicine of treatment chronic renal failure retention enema according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 parts of Herba Leonuris of 3 parts of Radix Angelicae Sinensis of Rhizoma Smilacis Glabrae

1 part of 2 parts of Fructus Kochiae of 3 portions of Cortex Phellodendris of Radix Et Rhizoma Rhei

1 part of 2 parts of Bulbus Fritillariae Thunbergii of 3 parts of Radix Morindae Officinaliss of Concha Ostreae

1 part of 2 parts of Radix Sophorae Flavescentis of 2 parts of Fructus Psoraleaes of Herba Taraxaci.