CN101085266A - Traditional Chinese medicine preparation for treating uremia - Google Patents

Traditional Chinese medicine preparation for treating uremia Download PDF

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Publication number
CN101085266A
CN101085266A CNA2007101179409A CN200710117940A CN101085266A CN 101085266 A CN101085266 A CN 101085266A CN A2007101179409 A CNA2007101179409 A CN A2007101179409A CN 200710117940 A CN200710117940 A CN 200710117940A CN 101085266 A CN101085266 A CN 101085266A
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parts
rhizoma
chinese medicine
portions
radix
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CNA2007101179409A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101179409A priority Critical patent/CN101085266A/en
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Abstract

The invention relates to a Chinese medicinal composition for treating uremia, which is prepared from more than ten kinds of Chinese medicinal herbs including cogongrass rhizome, corktree bark, oyster shell and alisol.

Description

Treat uremic a kind of Chinese medicine preparation
Technical field
The present invention relates to treat uremic a kind of Chinese medicine preparation, is that a kind of uremia for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Uremia is the later stage performance of multiple kidney disease.Its course of disease is longer, that the clinical manifestation majority has is weak, indigestion and loss of appetite, nausea, vomiting, dizziness, headache, flank pain, edema, epistaxis; urine is not generally reduced, but the later stage obviously reduces big dry stool or half congealed thin; shallow complexion or ash stagnate; body of the tongue is how light fat or indentation is arranged, or light dim, pulse condition stringy and rapid pulse or count accurately; or heavy thin, or slow.The easy being invaded by exogenous pathogen of patient is so manyly when going to a doctor cause state of an illness aggravation because of being invaded by exogenous pathogen.
Uremia generally belongs to the scope of cards such as Chinese medicine " obstruction and rejection ", " difficulty in urination ", " edema ", " asthenia ".From the document record, most of patients is similar to the description of " obstruction and rejection "." card control converge mend the difficulty in urination " day: " both closed and lattice, must urinary obstruction, between morning and evening, increase vomiting and nausea suddenly, this is because of the turbid pathogen three warmers that are jammed, and healthy energy must not lifting.So close to descend and anuria, lattice should be gone up and give birth to vomiting, and it is exhausted that negative and positive are closed, in case promptly dead, marquis the most endangers.”
The traditional Chinese medical science thinks that the basis of chronic uremia is a deficiency of spleen-YANG and kidneyYANG, insufficiency of the spleenly then loses the precise and tiny effect of transporting and transforming nutrients from foodstuff, and suffering from a deficiency of the kidney then influences the function of separating clear and excreting turbid, thereby is stranded in the turbid damp, changes to form poison.It is weakened body resistance that deficiency of spleen-YANG and kidneyYANG belongs to, and being stranded in the turbid damp then is the domination of pathogen, so uremia is the card marquis of vital QI being weakened and pathogen being violent, is this with weakened body resistance, and the domination of pathogen is mark.Sick yin-yang all loss for a long time sees that cold and heat are staggered so late stage uremia is every, and deficiency and excess sees that also treatment is difficulty quite.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as spleen deficiency of kidney-QI, spleen kidney qi Yin bivacuity, the hepatic and renal YIN deficiency, deficiency of both YIN and YANG clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the uremic a kind of Chinese medicine preparation of treatment.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Fructus Gardeniae (parched) of 1.5~6 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 portions of Cortex Phellodendris of Rhizoma Alismatis
0.1~2 part of 1.0~4 parts of Radix Et Rhizoma Rhei of 1.5~6 portions of Rhizoma Coptidis of Concha Ostreae
0.1~1 part of 1.0~4 parts of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Radix Scutellariaes of Herba Taraxaci.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 parts of Fructus Gardeniae (parched) of 2.5~3.5 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 portions of Cortex Phellodendris of Rhizoma Alismatis
0.5~1.5 part of 1.5~2.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 portions of Rhizoma Coptidis of Concha Ostreae
0.3~0.7 part of 1.5~2.5 parts of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Radix Scutellariaes of Herba Taraxaci.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
1 part of 2 portions of Semen Plantaginis of 3 portions of Cortex Phellodendris of Rhizoma Alismatis
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Coptidis of Concha Ostreae
0.5 part of 2 parts of Rhizoma Pinelliae Preparatum of 2 parts of Radix Scutellariaes of Herba Taraxaci.
Drug action mechanism among the present invention is as follows:
The Rhizoma Imperatae property of medicine is sweet, and is cold.GUIXIN, lung, stomach, urinary bladder channel.Has clearing away heat and promoting production of body fluid, cooling blood for hemostasis, the effect of inducing diuresis for treating stranguria syndrome.Can treat the calentura excessive thirst, dyspnea and cough due to lung-heat, the gastric heat vomiting, heat in blood is hemorrhage, the puckery pain of dribbling urination, edema, jaundice etc.(the 992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter , mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Taraxaci property of medicine hardship, sweet, cold.Return liver, stomach warp.Has heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.Can treat acute mastitis, lung abscess, acute appendicitis, mumps, scrofula, furuncle carbuncle toxin, conjunctival congestion and swelling pain, cat fever, cough, laryngopharynx swelling and pain, gastritis, enteritis, dysentery, hepatitis, cholecystitis, urinary tract infection, snake bite and insect sting, burn and scald etc.(the 3427th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Polygoni Cuspidati property of medicine hardship is slightly cold.Return liver, gallbladder, lung meridian.Has blood circulation promoting and blood stasis dispelling, dampness removing jaundice eliminating, the effect of heat-clearing and toxic substances removing.Can treat women's amenorrhea, dysmenorrhea, lochiostasis , lumps in the chest and abdomen, rheumatic arthralgia, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, injury from falling down, sore swollen toxin, burn due to hot liquid or fire etc.(the 1871st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever , Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Cure mainly the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, the furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Imperatae, Rhizoma Alismatis, Radix Et Rhizoma Rhei and Concha Ostreae; With Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Rhizoma Coptidis, Herba Taraxaci, Rhizoma Pinelliae Preparatum, Fructus Gardeniae (parched) and Radix Scutellariae is ministerial drug; With Semen Plantaginis is adjuvant.All medicines are harmonious, tool enriching yin and nourishing kidney altogether, the effect of the controlling nocturnal emission with astringent drugs that nourishes blood.Treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment uremia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat uremia, and uremic prevention is also had good effect, and treatment uremia has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treating uremic therapeutic effect; Treatment uremic patient 15 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.Produce effects 6 examples account for 40%, and effective 7 examples account for 46.67%, and invalid 2 examples account for 13.33%, and total effective rate reaches 86.67%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
1 part of 2 portions of Semen Plantaginis of 3 portions of Cortex Phellodendris of Rhizoma Alismatis
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Coptidis of Concha Ostreae
0.5 part of 2 parts of Rhizoma Pinelliae Preparatum of 2 parts of Radix Scutellariaes of Herba Taraxaci.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The uremic decoction of the treatment that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the uremic a kind of Chinese medicine preparation of treatment is characterized in that it is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Fructus Gardeniae (parched) of 1.5~6 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 portions of Cortex Phellodendris of Rhizoma Alismatis
0.1~2 part of 1.0~4 parts of Radix Et Rhizoma Rhei of 1.5~6 portions of Rhizoma Coptidis of Concha Ostreae
0.1~1 part of 1.0~4 parts of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Radix Scutellariaes of Herba Taraxaci.
2, the uremic a kind of Chinese medicine preparation of treatment according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 1.5~2.5 parts of Fructus Gardeniae (parched) of 2.5~3.5 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 portions of Cortex Phellodendris of Rhizoma Alismatis
0.5~1.5 part of 1.5~2.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 portions of Rhizoma Coptidis of Concha Ostreae
0.3~0.7 part of 1.5~2.5 parts of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Radix Scutellariaes of Herba Taraxaci.
3, the uremic a kind of Chinese medicine preparation of treatment according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Rhizoma Polygoni Cuspidati of Rhizoma Imperatae
1 part of 2 portions of Semen Plantaginis of 3 portions of Cortex Phellodendris of Rhizoma Alismatis
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Coptidis of Concha Ostreae
0.5 part of 2 parts of Rhizoma Pinelliae Preparatum of 2 parts of Radix Scutellariaes of Herba Taraxaci.
CNA2007101179409A 2007-06-26 2007-06-26 Traditional Chinese medicine preparation for treating uremia Pending CN101085266A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283957A (en) * 2011-08-18 2011-12-21 荣成市商贸城卫生所 Traditional Chinese medicine composition for treating nephropathy
CN102688414A (en) * 2012-06-25 2012-09-26 许梅 Traditional Chinese medicine composition for treating uremia by being matched with hematodialysis, preparation method and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283957A (en) * 2011-08-18 2011-12-21 荣成市商贸城卫生所 Traditional Chinese medicine composition for treating nephropathy
CN102688414A (en) * 2012-06-25 2012-09-26 许梅 Traditional Chinese medicine composition for treating uremia by being matched with hematodialysis, preparation method and application thereof
CN102688414B (en) * 2012-06-25 2013-10-30 青岛华仁技术孵化器有限公司 Traditional Chinese medicine composition for treating uremia by being matched with hematodialysis, preparation method and application thereof

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Open date: 20071212