CN101116717A - Chinese medicine preparation for treating non-gonococcal urethritis - Google Patents

Chinese medicine preparation for treating non-gonococcal urethritis Download PDF

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CN101116717A
CN101116717A CNA2007101209743A CN200710120974A CN101116717A CN 101116717 A CN101116717 A CN 101116717A CN A2007101209743 A CNA2007101209743 A CN A2007101209743A CN 200710120974 A CN200710120974 A CN 200710120974A CN 101116717 A CN101116717 A CN 101116717A
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rhizoma
chinese medicine
radix
nongonococcal urethritis
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

The invention relates to a Chinese materia medica preparation for healing nongonococcal urethritis which takes more than 10 species of Chinese herbal medicines as raw materials, such as christina loosestrife herb, glabrous greenbrier rhizome, cluster mallow fruit, radix et rhizoma rhei and so on. The invention has the effects of clearing away heat and toxic material and promoting diuresis for stranguria. Based on the traditional Chinese medicine dialectical cure, the invention is developed by latest modern technological research findings. The aim of the invention is to provide a Chinese materia medica preparation for healing nongonococcal urethritis. The invention has the characteristics of certain curative effect, safety and convenience, non-toxic side effects and low price.

Description

A kind of Chinese medicine preparation for the treatment of nongonococcal urethritis
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of nongonococcal urethritis, is that a kind of nongonococcal urethritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Nongonococcal urethritis is the urethritis that is caused by other pathogen beyond the Diplococcus gonorrhoeae, it is a kind of sexually transmitted disease (STD), the performance of urethritis is arranged clinically, but in urethral secretions, can not find out gonococcus, wherein also comprise the persistent gonorrhea posterior urethritis of gonorrhea healing back symptom.Because the women not only has the inflammation of urethra when suffering from primary disease, and the inflammation of reproductive tract such as cervicitis is arranged, therefore can be described as again " non-gonococcal urogenital infections ".Main clinical manifestation is urethral orifice discomfort, dysurea, urgent micturition, dysuria, and the visible leucorrhea of women is many etc.Find that in clinical because Drug resistance, the broad ectrum antibiotic therapeutic effect is more and more lower.
Nongonococcal urethritis belongs to the traditional Chinese medical science " stranguria ", " it is turbid to drown ", " nebulousurine ", and the women then belongs to " leukorrhagia ", " pudendal pruritus " etc.
Chinese medicine thinks that nongonococcal urethritis and sexual life are unclean, directly or indirectly experiences special foul heresy, leads to damp and hotly, and the damp and hot malicious heresy knot of fighting is invaded the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the multiple abscess bladder, and the smoked urethra that burns, and make bladder qi dysfunction, and disturbance in water passage, urinary catheter (road) blocks relevant; Or because of stagnation of QI due to depression of the liver, with the passing of time strongly fragrant and fire-transformation is invaded bladder down, makes gasification not all right, disturbance in water passage and be pouring; Also can be because of impairment of the kidney due to indulgence in sexual activities or damp and hot evil poison by the internal organs superinverse to dirty, injure kidney qi, the prolonged illness imapirment of the spleen and stomach, deficiency of spleen and stomach, it is not normal to gasify, and can not take the photograph to receive fat and stranguria with turbid discharge.The state of an illness is with the passing of time then drenched body void for a long time, and impairment caused by overstrain is excessive, or poison of drug hinders, and decreases cloudy consumption gas so that deficiency of spleen and stomach, and functioning of bladder is had no right, and damp is loved for a long time.The traditional Chinese medical science is divided at the treatment nongonococcal urethritis: the dialectical treatments of disease type such as damp invasion of lower energizer, stagnation of QI due to depression of the liver, the hepatic and renal YIN deficiency, deficiency of spleen and stomach obtain effect preferably, and do not recur.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of nongonococcal urethritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.5~6 parts of 1.5~6 parts of Rhizoma Smilacis Glabraes of 1.5~6 portions of Herba Lysimachiaes of Rhizoma Alismatis
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
Bi
Figure A20071012097400031
0.1 0.1~2 part of 0.1~2 portion of Semen Plantaginis of~2 parts of Rhizoma Acori Graminei
0.1~2 part of 0.1~2 part of Radix Et Rhizoma Rhei of 0.1~2 part of Semen Abutili of Cortex Phellodendri.
The weight proportion of each crude drug of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Rhizoma Smilacis Glabraes of 2.5~3.5 portions of Herba Lysimachiaes of Rhizoma Alismatis
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
Bi
Figure A20071012097400041
0.5 0.5~1.5 part of 0.5~1.5 portion of Semen Plantaginis of~1.5 parts of Rhizoma Acori Graminei
0.5~1.5 part of 0.5~1.5 part of Radix Et Rhizoma Rhei of 0.5~1.5 part of Semen Abutili of Cortex Phellodendri.
The weight proportion of each crude drug of optimum formula of the present invention is:
3 parts of 3 parts of Rhizoma Smilacis Glabraes of 3 portions of Herba Lysimachiaes of Rhizoma Alismatis
2 parts in 2 parts of Poria of 2 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
Bi 1 part of 1 portion of Semen Plantaginis of 1 part of Rhizoma Acori Graminei
1 part of 1 part of Radix Et Rhizoma Rhei of 1 part of Semen Abutili of Cortex Phellodendri.
Drug action mechanism among the present invention is as follows:
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Herba Lysimachiae property of medicine, cold.Return liver, gallbladder, kidney, urinary bladder channel.Have heat clearing away, dampness removing, treating stranguria, calculus, antidotal effect.Can treat jaundice due to damp-heat, pyretic stranguria, oedema due to nephritis, liver, gallbladder and urinary system calculus, pyretic toxicity carbuncle, venom etc.(the 1967th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Smilacis Glabrae nature and flavor are sweet, light, flat.Return liver, stomach warp.Has heat-clearing and toxic substances removing, wind-damp dispelling, bone and muscle strengthening, sharp joint, anticancer effect.Can treat damp and hot sore, eczema, rheumatic ostalgia, limbs contracture, Fructus Myricae rubrae malignant boil, urinary system infection, syphilis, stranguria with turbid discharge, stranguria leucorrhea, dyspepsia, diarrhoea, beriberi, furuncle, carbuncle, scrofula etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 87th page).
Rhizoma Atractylodis Macrocephalae property of medicine hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Bi
Figure A20071012097400051
Property of medicine hardship, flat.Return liver, stomach, urinary bladder channel.It is turbid to have dampness removing, the effect of wind-damp dispelling.Can treat stranguria marked by chyluria, nebulousurine, leukorrhagia, skin infection, eczema, rheumatic arthralgia etc.(the 2890th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Acori Graminei property of medicine suffering, hardship, tepor.GUIXIN, liver, spleen channel.Have and eliminate phlegm for resuscitation, removing dampness to restore normal function of the stomach, the effect of mind calming benefit will.Can treat the calentura coma, syncope due to accumulation of phlegm, forgetful, insomnia, tinnitus, deafness, fasting dysentery, rheumatic arthralgia etc.(the 854th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis nature and flavor are sweet, be slightly cold.Return liver, kidney, lung, small intestinal, urinary bladder channel.Has clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, the effect of removing heat from the lung and dissipating phlegm.Can treat the cough due to lung-heat, urinary system infection, calculus, gastritis edema, dysuria, enteritis, bacillary dysentery, acute icterohepatitisshock, bronchitis, acute eye conjunctivitis, stranguria with turbid discharge, leukorrhagia, hematuria, edema, hematodiarrhoea is had loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat tonsillitis, cough, skin ulcer etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 291st page).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever , Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Abutili property of medicine is sweet, and is cold.Return large intestine, small intestinal, urinary bladder channel.Has relieving stranguria by diuresis, the effect of laxation relieving constipation.Can treat gonorrhea, edema, constipation, galactozemia etc.(the 1053rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Alismatis, Herba Lysimachiae and Rhizoma Smilacis Glabrae; With the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Poria, Bi
Figure A20071012097400052
, Semen Plantaginis and Cortex Phellodendri be ministerial drug; With Rhizoma Acori Graminei, Semen Abutili and Radix Et Rhizoma Rhei is adjuvant.All medicines are harmonious, and are total to the tool heat-clearing and toxic substances removing, the effect of relieving stranguria by diuresis.The treatment nongonococcal urethritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment nongonococcal urethritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat nongonococcal urethritis, and the prevention of nongonococcal urethritis is also had good effect, and the treatment nongonococcal urethritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment nongonococcal urethritis; Treatment nongonococcal urethritis patient 26 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 18 examples and account for 69.23%, 6 examples that take a turn for the better account for 23.07%, and more 2 examples do not account for 7.69%, and total effective rate reaches 92.3%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
3 parts of 3 parts of Rhizoma Smilacis Glabraes of 3 portions of Herba Lysimachiaes of Rhizoma Alismatis
2 parts in 2 parts of Poria of 2 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
Bi
Figure A20071012097400061
1 part of 1 portion of Semen Plantaginis of 1 part of Rhizoma Acori Graminei
1 part of 1 part of Radix Et Rhizoma Rhei of 1 part of Semen Abutili of Cortex Phellodendri.
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment nongonococcal urethritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of nongonococcal urethritis is characterized in that it is made by following raw materials by weight proportions:
1.5~6 parts of 1.5~6 parts of Rhizoma Smilacis Glabraes of 1.5~6 portions of Herba Lysimachiaes of Rhizoma Alismatis
1.0~4 parts in 1.0~4 parts of Poria of 1.0~4 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
0.1~2 part of 0.1~2 portion of Semen Plantaginis of 0.1~2 part of Rhizoma Acori Graminei of Rhizoma Dioscoreae Septemlobae
0.1~2 part of 0.1~2 part of Radix Et Rhizoma Rhei of 0.1~2 part of Semen Abutili of Cortex Phellodendri.
2. a kind of Chinese medicine preparation for the treatment of nongonococcal urethritis according to claim 1, wherein the weight proportion of each crude drug is:
2.5~3.5 parts of 2.5~3.5 parts of Rhizoma Smilacis Glabraes of 2.5~3.5 portions of Herba Lysimachiaes of Rhizoma Alismatis
1.5~2.5 parts in 1.5~2.5 parts of Poria of 1.5~2.5 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
0.5~1.5 part of 0.5~1.5 portion of Semen Plantaginis of 0.5~1.5 part of Rhizoma Acori Graminei of Rhizoma Dioscoreae Septemlobae
0.5~1.5 part of 0.5~1.5 part of Radix Et Rhizoma Rhei of 0.5~1.5 part of Semen Abutili of Cortex Phellodendri.
3. a kind of Chinese medicine preparation for the treatment of nongonococcal urethritis according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 3 parts of Rhizoma Smilacis Glabraes of 3 portions of Herba Lysimachiaes of Rhizoma Alismatis
2 parts in 2 parts of Poria of 2 parts of Radix Salviae Miltiorrhizaes of the Rhizoma Atractylodis Macrocephalae
1 part of 1 portion of Semen Plantaginis of 1 part of Rhizoma Acori Graminei of Rhizoma Dioscoreae Septemlobae
1 part of 1 part of Radix Et Rhizoma Rhei of 1 part of Semen Abutili of Cortex Phellodendri.
CNA2007101209743A 2007-08-29 2007-08-29 Chinese medicine preparation for treating non-gonococcal urethritis Pending CN101116717A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102688436A (en) * 2012-05-08 2012-09-26 安徽智远生物科技有限公司 Chinese medicinal composition for treating stranguria and preparation method thereof
CN105311497A (en) * 2014-07-13 2016-02-10 胡培芹 Chinese patent medicine for treating non-gonococcal urethritis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102688436A (en) * 2012-05-08 2012-09-26 安徽智远生物科技有限公司 Chinese medicinal composition for treating stranguria and preparation method thereof
CN102688436B (en) * 2012-05-08 2014-04-09 安徽智远生物科技有限公司 Traditional Chinese medicinal composition for treating stranguria and preparation method thereof
CN105311497A (en) * 2014-07-13 2016-02-10 胡培芹 Chinese patent medicine for treating non-gonococcal urethritis

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