CN101066428A - Medicine for treating sterility of aspermia and its prepn process - Google Patents
Medicine for treating sterility of aspermia and its prepn process Download PDFInfo
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- CN101066428A CN101066428A CNA2007101000827A CN200710100082A CN101066428A CN 101066428 A CN101066428 A CN 101066428A CN A2007101000827 A CNA2007101000827 A CN A2007101000827A CN 200710100082 A CN200710100082 A CN 200710100082A CN 101066428 A CN101066428 A CN 101066428A
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Abstract
The present invention provides medicine for treating sterility of aspermia. The medicine is prepared with over ten kinds of Chinese medicinal materials, including red sage, zedoary, Chuanxiong rhizome, red peony root, etc. It has the functions of promoting blood circulation to disperse blood clots, invigorating kidney and producing sperm. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The medicine has the features of determined curative effect, high safety, no toxic side effect and low cost.
Description
Technical field
The present invention relates to medicine for the treatment of little semen infertility and preparation method thereof, is that the treatment little semen infertility is the medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
The semen volume that normal health male once discharges is generally 2～6ml, if the lack of quantity of spermatic fluid of discharging during each sexual intercourse in 1ml, or only has several persons to be called low semen volumes.Because not enough caused sterile 1.8% of the whole infertility that accounts for of semen volume.Semen volume how many very big physiological variations arranged, with sexual intercourse frequency, position, time, sexual excitation power and the mental status, physical factors etc. confidential relation is arranged.This disease traditional Chinese medical science is referred to as oligospermia, promptly records in " interior warp ".The oligospermia that the traditional Chinese medical science is sayed had both comprised the minimizing of semen volume, also may comprise the minimizing of sperm number.The traditional Chinese medical science thinks that low semen volumes is many by congenital defect, the natural endowment weakness; Or the day after tomorrow lose to support, plain body weakness, or obstinate disease, or excessive thinking, impairment caused by overstrain heart spleen, QI and blood is all hindered, so that the change source is short, essential substance for reproduction generates not enough; Or exhaustion due to sexual indulgence too, consumes due to the kidney essense.Person due to smart chamber of thermal burn or the orifice for discharging seminal fluid retardance is also arranged.Plain body interior-heat, or cross and obey the supporing yang product of warm-dryness syndrome, or catching pathogenic heat, pyrogenicity is contained impairment of YIN; Or eating and drinking without temperance, element is had a liking for rich and fatty diet, and is damp and hot interior living, the smart chamber of making a bet; Or the damp and hot heresy of diseases caused by exogenous pathogenic factor, stifling smart chamber, it is turbid that seminal fluid becomes, stasis of blood resistance vein; Or face the room and bear essence and do not let out, the smart chamber of fire volt, retention of corruptive essence causes the smart road of orifice for discharging seminal fluid to be obstructed, and the seminal fluid drainage difficulty all can cause lack of quantity of spermatic fluid.The primary disease clinical manifestation is that the lack of quantity of spermatic fluid person is common thin, accompanies with seminal fluid being thin and cold, and clinically have soreness of the waist and knees more, spiritlessness and weakness, and body is thin and weak, or distention and pain in the lower abdomen, or twinge etc. during ejaculation.The traditional Chinese medical science is divided into deficiency of kidney-essence clinically, the kidney yang loss, and damp invasion of lower energizer, QI and blood deficiency, the smart chamber of thermal burn, disease type Coryza Treated by Syndrome Differentiation such as smart road obstruction obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide medicine for the treatment of little semen infertility and preparation method thereof.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Morindae Officinaliss of 1.5～6 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
0.1～2 part of 1.0～4 parts of Herba Epimedii of 1.5～6 parts of Radix Rehmanniae of Rhizoma Curcumae
0.1～2 part of 1.0～4 parts of Cornu Cervi Degelatinatum of 1.0～4 parts of Fructus Aurantiis of Rhizoma Chuanxiong
0.1～2 part of 1.0～4 portions of Radix Cyathulae of 1.0～4 parts of Semen Cuscutae of Radix Paeoniae Rubra
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Morindae Officinaliss of 2.5～3.5 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
0.5～1.5 part of 1.5～2.5 parts of Herba Epimedii of 2.5～3.5 parts of Radix Rehmanniae of Rhizoma Curcumae
0.5～1.5 part of 1.5～2.5 parts of Cornu Cervi Degelatinatum of 1.5～2.5 parts of Fructus Aurantiis of Rhizoma Chuanxiong
0.5～1.5 part of 1.5～2.5 portions of Radix Cyathulae of 1.5～2.5 parts of Semen Cuscutae of Radix Paeoniae Rubra
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra
Drug action mechanism among the present invention is as follows:
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Cornu Cervi Degelatinatum property of medicine is salty, puckery, temperature.Return kidney, Liver Channel.Has reinforcing the kidney and supporting YANG, anastaltic effect.Can treat emission due to deficiency of the kidney, night sweat, anorexia and loose stool, chronic diarrhea chronic dysentery, metrorrhagia, leukorrhagia, frequent micturition, the enuresis, dribble of urine, skin infection disunion of a specified duration, wound hemorrhage etc.(the 3118th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Salviae Miltiorrhizae and Rhizoma Curcumae, is ministerial drug with Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Radix Rehmanniae, Fructus Aurantii, Semen Cuscutae and Radix Morindae Officinalis; With Herba Epimedii, Cornu Cervi Degelatinatum and Radix Cyathulae is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of kidney-tonifying sperm-generating.The treatment little semen infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment little semen infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat little semen infertility, and the prevention of little semen infertility is also had good effect, and the treatment little semen infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment little semen infertility; Treatment little semen infertility patient 22 examples.Take embodiment 1 decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.11 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 40.9%, and more 2 examples do not account for 9.1%, and total effective rate reaches 90.9%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment little semen infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules take by weighing raw material by following weight:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra
Preparation method is to get above-mentioned raw materials to clean, and roguing decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three months is a course of treatment.
Embodiment 3 tablets take by weighing raw material by following weight:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra
Preparation method is to get above-mentioned raw materials to clean, roguing decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, three months is a course of treatment.
Embodiment 4 granules take by weighing raw material by following weight:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra
Preparation method is to get above-mentioned raw materials to clean, roguing, decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, and the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, three months is a course of treatment.
Claims (3)
1, medicine and preparation method thereof of treatment little semen infertility is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Morindae Officinaliss of 1.5～6 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
0.1～2 part of 1.0～4 parts of Herba Epimedii of 1.5～6 parts of Radix Rehmanniae of Rhizoma Curcumae
0.1～2 part of 1.0～4 parts of Cornu Cervi Degelatinatum of 1.0～4 parts of Fructus Aurantiis of Rhizoma Chuanxiong
0.1～2 part of 1.0～4 portions of Radix Cyathulae of 1.0～4 parts of Semen Cuscutae of Radix Paeoniae Rubra.
2, medicine of treatment little semen infertility according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Morindae Officinaliss of 2.5～3.5 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
0.5～1.5 part of 1.5～2.5 parts of Herba Epimedii of 2.5～3.5 parts of Radix Rehmanniae of Rhizoma Curcumae
0.5～1.5 part of 1.5～2.5 parts of Cornu Cervi Degelatinatum of 1.5～2.5 parts of Fructus Aurantiis of Rhizoma Chuanxiong
0.5～1.5 part of 1.5～2.5 portions of Radix Cyathulae of 1.5～2.5 parts of Semen Cuscutae of Radix Paeoniae Rubra.
3, medicine of treatment little semen infertility according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Radix Morindae Officinaliss of 3 parts of Radix Angelicae Sinensis of Radix Salviae Miltiorrhizae
1 part of 2 parts of Herba Epimedii of 3 parts of Radix Rehmanniae of Rhizoma Curcumae
1 part of 2 parts of Cornu Cervi Degelatinatum of 2 parts of Fructus Aurantiis of Rhizoma Chuanxiong
1 part of 2 portions of Radix Cyathulae of 2 parts of Semen Cuscutae of Radix Paeoniae Rubra.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101000827A CN101066428A (en) | 2007-06-05 | 2007-06-05 | Medicine for treating sterility of aspermia and its prepn process |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101000827A CN101066428A (en) | 2007-06-05 | 2007-06-05 | Medicine for treating sterility of aspermia and its prepn process |
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| CN101066428A true CN101066428A (en) | 2007-11-07 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836272A (en) * | 2012-09-10 | 2012-12-26 | 王仲举 | Medicinal composition for treating prostate hyperplasia |
| CN109288979A (en) * | 2018-11-16 | 2019-02-01 | 南京长江医院集团有限公司 | Sheng Jing Yu Zi Tang |
-
2007
- 2007-06-05 CN CNA2007101000827A patent/CN101066428A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836272A (en) * | 2012-09-10 | 2012-12-26 | 王仲举 | Medicinal composition for treating prostate hyperplasia |
| CN102836272B (en) * | 2012-09-10 | 2014-10-15 | 王仲举 | Medicinal composition for treating prostate hyperplasia |
| CN109288979A (en) * | 2018-11-16 | 2019-02-01 | 南京长江医院集团有限公司 | Sheng Jing Yu Zi Tang |
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Open date: 20071107 |