CN101066405A - Chinese medicine composition for treating sterility of aspermia - Google Patents

Abstract

The present invention provides Chinese medicine composition for treating sterility of aspermia. The Chinese medicine composition is prepared with over ten kinds of Chinese medicinal materials, including coix seed, phellodendron bark, capillary artemisia, tuckahoe, etc. It has the functions of clearing away heat, eliminating dampness, nourishing yin and producing sperm. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine composition has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

The Chinese medicine composition of treatment little semen infertility

Technical field

The present invention relates to treat the Chinese medicine composition of little semen infertility, is that the treatment little semen infertility is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

The semen volume that normal health male once discharges is generally 2～6ml, if the lack of quantity of spermatic fluid of discharging during each sexual intercourse in 1ml, or only has several persons to be called low semen volumes.Because not enough caused sterile 1.8% of the whole infertility that accounts for of semen volume.Semen volume how many very big physiological variations arranged, with sexual intercourse frequency, position, time, sexual excitation power and the mental status, physical factors etc. confidential relation is arranged.This disease traditional Chinese medical science is referred to as oligospermia, promptly records in " interior warp ".The oligospermia that the traditional Chinese medical science is sayed had both comprised the minimizing of semen volume, also may comprise the minimizing of sperm number.The traditional Chinese medical science thinks that low semen volumes is many by congenital defect, the natural endowment weakness; Or the day after tomorrow lose to support, plain body weakness, or obstinate disease, or excessive thinking, impairment caused by overstrain heart spleen, QI and blood is all hindered, so that the change source is short, essential substance for reproduction generates not enough; Or exhaustion due to sexual indulgence too, consumes due to the kidney essense.Person due to smart chamber of thermal burn or the orifice for discharging seminal fluid retardance is also arranged.Plain body interior-heat, or cross and obey the supporing yang product of warm-dryness syndrome, or catching pathogenic heat, pyrogenicity is contained impairment of YIN; Or eating and drinking without temperance, element is had a liking for rich and fatty diet, and is damp and hot interior living, the smart chamber of making a bet; Or the damp and hot heresy of diseases caused by exogenous pathogenic factor, stifling smart chamber, it is turbid that seminal fluid becomes, stasis of blood resistance vein; Or face the room and bear essence and do not let out, the smart chamber of fire volt, retention of corruptive essence causes the smart road of orifice for discharging seminal fluid to be obstructed, and the seminal fluid drainage difficulty all can cause lack of quantity of spermatic fluid.The primary disease clinical manifestation is that the lack of quantity of spermatic fluid person is common thin, accompanies with seminal fluid being thin and cold, and clinically have soreness of the waist and knees more, spiritlessness and weakness, and body is thin and weak, or distention and pain in the lower abdomen, or twinge etc. during ejaculation.The traditional Chinese medical science is divided into deficiency of kidney-essence clinically, the kidney yang loss, and damp invasion of lower energizer, QI and blood deficiency, the smart chamber of thermal burn, disease type Coryza Treated by Syndrome Differentiation such as smart road obstruction obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine composition for the treatment of little semen infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Herba Artemisiae Scopariaes of 1.5～6 portions of Cortex Phellodendris of Semen Coicis

1.0～4 parts of 1.0～4 parts of Rhizoma Anemarrhenaes of 1.0～4 parts of Poria of Radix Cyathulae

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Fructus Gardeniae (parched) of Fructus Lycii

0.1～2 part of 0.1～2 part of Rhizoma Atractylodis of 0.1～2 portion of Semen Plantaginis of Fructus Ligustri Lucidi

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 2.5～3.5 portions of Herba Artemisiae Scopariaes of 2.5～3.5 portions of Cortex Phellodendris of Semen Coicis

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Anemarrhenaes of 1.5～2.5 parts of Poria of Radix Cyathulae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Fructus Gardeniae (parched) of Fructus Lycii

0.5～1.5 part of 0.5～1.5 part of Rhizoma Atractylodis of 0.5～1.5 portion of Semen Plantaginis of Fructus Ligustri Lucidi

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 3 portions of Herba Artemisiae Scopariaes of 3 portions of Cortex Phellodendris of Semen Coicis

2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 parts of Poria of Radix Cyathulae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Fructus Gardeniae (parched) of Fructus Lycii

1 part of 1 part of Rhizoma Atractylodis of 1 portion of Semen Plantaginis of Fructus Ligustri Lucidi

Drug action mechanism among the present invention is as follows:

The Semen Coicis property of medicine is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.Has the dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.(the 3725th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The little hardship of the Herba Artemisiae Scopariae property of medicine, little suffering are slightly cold.Return spleen, stomach, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Can treat jaundice, dysuria, eczema pruritus etc.(the 2146th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Atractylodis property of medicine suffering, hardship, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, the effect that makes eye bright.Can treat the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, the exterior syndrome folder is wet, a heavy sensation of the body pain, arthromyodynia domination of damp pathogen, podomere are ached and are being weighed, and flaccidity is sprained, nyctalopia etc.(the 1485th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Coicis and Cortex Phellodendri, is ministerial drug with Herba Artemisiae Scopariae, Radix Cyathulae, Poria, the Rhizoma Anemarrhenae, Fructus Lycii, Fructus Gardeniae (parched) and Rhizoma Alismatis; With Fructus Ligustri Lucidi, Semen Plantaginis and Rhizoma Atractylodis is adjuvant.All medicines are harmonious, and are total to the tool heat clearing and damp drying, the effect of yin nourishing spermatogenesis.The treatment little semen infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment little semen infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat little semen infertility, and the prevention of little semen infertility is also had good effect, and the treatment little semen infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment little semen infertility; Treatment little semen infertility patient 12 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 50%, and 5 examples that take a turn for the better account for 41.67%, and more 1 example does not account for 8.33%, and total effective rate reaches 91.67%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 3 portions of Herba Artemisiae Scopariaes of 3 portions of Cortex Phellodendris of Semen Coicis

2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 parts of Poria of Radix Cyathulae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Fructus Gardeniae (parched) of Fructus Lycii

1 part of 1 part of Rhizoma Atractylodis of 1 portion of Semen Plantaginis of Fructus Ligustri Lucidi

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment little semen infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine composition of treatment little semen infertility is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Herba Artemisiae Scopariaes of 1.5～6 portions of Cortex Phellodendris of Semen Coicis

1.0～4 parts of 1.0～4 parts of Rhizoma Anemarrhenaes of 1.0～4 parts of Poria of Radix Cyathulae

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Fructus Gardeniae (parched) of Fructus Lycii

0.1～2 part of 0.1～2 part of Rhizoma Atractylodis of 0.1～2 portion of Semen Plantaginis of Fructus Ligustri Lucidi.

2, the Chinese medicine composition of treatment little semen infertility according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 2.5～3.5 portions of Herba Artemisiae Scopariaes of 2.5～3.5 portions of Cortex Phellodendris of Semen Coicis

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Anemarrhenaes of 1.5～2.5 parts of Poria of Radix Cyathulae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Fructus Gardeniae (parched) of Fructus Lycii

0.5～1.5 part of 0.5～1.5 part of Rhizoma Atractylodis of 0.5～1.5 portion of Semen Plantaginis of Fructus Ligustri Lucidi.

3, the Chinese medicine composition of treatment little semen infertility according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 3 portions of Herba Artemisiae Scopariaes of 3 portions of Cortex Phellodendris of Semen Coicis

2 parts of 2 parts of Rhizoma Anemarrhenaes of 2 parts of Poria of Radix Cyathulae

2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Fructus Gardeniae (parched) of Fructus Lycii

1 part of 1 part of Rhizoma Atractylodis of 1 portion of Semen Plantaginis of Fructus Ligustri Lucidi.