CN101066413A - Chinese medicine for treating sterility of un-liquefiable sperm - Google Patents

Abstract

The present invention provides Chinese medicine for treating sterility of un-liquefiable sperm. The Chinese medicine is prepared with over ten kinds of Chinese medicinal materials, including Rizoma dioscoreae, bitter caramon, glabrous greenbrier rhizome, etc. It has the functions of warming and invigorating spleen and kidney, relieving obstruction and eliminating turbid urine. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

The Chinese medicine preparation of treatment infertility due to non-liquefied sperm

Technical field

The present invention relates to treat the Chinese medicine preparation of infertility due to non-liquefied sperm, is that the treatment infertility due to non-liquefied sperm is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Seminal fluid excretes, and in 37 ℃ of constant temperature, does not liquefy in 60 minutes or still contains the grumeleuse that does not liquefy in 60 minutes, is called seminal fluid not liquefaction.Seminal fluid not liquefaction makes sperm motility limited, slows down or suppress sperm to enter cavity of uterus fertilization and cause infertile.According to statistics, seminal fluid not liquefaction accounts for 2.51%～42.65% of the male infertility cause of disease.The traditional Chinese medical science is thought, the generation of seminal fluid not liquefaction, and normal and sexual strain, or masturbation is frequent, and hyperactivity of fire caused by deficiency of YIN, seminal fluid are subjected to bright and sticky difficultyization relevant; Or plain volume elements YANG deficiency, the deficiency of YIN and sun, smart palace deficiency and coldness, sun is not changed the moon and seminal fluid not liquefaction; Or damp invasion of lower energizer, retardance Yang Dao, smart turbid obscuring and seminal fluid not liquefaction; Or the fertile abundant expectoration of body, blood stasis due to qi deficiency or blood stasis body constitution, the resistance of the orifice for discharging seminal fluid stasis of blood, seminal fluid not liquefaction and cause sterile.The primary disease clinical manifestation is 1, seminal fluid is sticky, or is gelatin, even in the form of sheets, block, lumps, excretes and does not still liquefy in 60 minutes; 2, symptoms such as ejaculation difficulty, painful ejaculation, hemospermia can be arranged, or have diseases such as sexual impotence, premature ejaculation, seminal emission concurrently; 3, part patient Chang Yin is sterile and cause neural mental symptom, as insomnia, cardiopalmus, dizziness, alopecia, night sweat, fatigue etc.The traditional Chinese medical science is divided into insufficiency of kidney-YANG clinically, hyperactivity of fire caused by deficiency of YIN, and knot in the damp invasion of lower energizer, phlegm-damp, the stasis of blood hinders disease type Coryza Treated by Syndrome Differentiation such as smart road, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine preparation for the treatment of infertility due to non-liquefied sperm.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 1.5～6 Fen Rhizoma Dioscoreae Septemlobae

1.0～4 parts of 1.0～4 parts of Radixs Astragali of 1.5～6 parts of Poria of Rhizoma Smilacis Glabrae

1.0～4 parts of 1.0～4 portions of Cortex Phellodendris of 1.0～4 parts of Radix Codonopsis of Radix Cyathulae

1.0～4 parts of 0.1～2 part of Radix Salviae Miltiorrhizaes of 0.1～2 part of Radix Linderae of Rhizoma Acori Graminei

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 2.5～3.5 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 2.5～3.5 Fen Rhizoma Dioscoreae Septemlobae

1.5～2.5 parts of 1.5～2.5 parts of Radixs Astragali of 2.5～3.5 parts of Poria of Rhizoma Smilacis Glabrae

1.5～2.5 parts of 1.5～2.5 portions of Cortex Phellodendris of 1.5～2.5 parts of Radix Codonopsis of Radix Cyathulae

1.5～2.5 parts of 0.5～1.5 part of Radix Salviae Miltiorrhizaes of 0.5～1.5 part of Radix Linderae of Rhizoma Acori Graminei

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 3 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 3 Fen Rhizoma Dioscoreae Septemlobae

2 parts of 2 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Smilacis Glabrae

2 parts of 2 portions of Cortex Phellodendris of 2 parts of Radix Codonopsis of Radix Cyathulae

2 parts of 1 part of Radix Salviae Miltiorrhizaes of 1 part of Radix Linderae of Rhizoma Acori Graminei

Drug action mechanism among the present invention is as follows:

Fructus Alpiniae Oxyphyllae property of medicine suffering, temperature.Return spleen, kidney channel.Has the warming spleen and stopping diarrha saliva of taking the photograph, the effect of warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Can treat Deficiency and coldness of spleen and stomach, vomiting is had loose bowels, cold type of pain in the abdomen, mouthful many salivas, enuresis due to deficiency of the kidney, frequent micturition, seminal emission, nebulousurine etc.(the 2699th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Smilacis Glabrae property of medicine is sweet, light, and is flat.Return liver,kidney,spleen, stomach warp.Have removing damp-heat, let out turbid detoxifcation, the effect of easing joint movement.Can treat syphilis, stranguria with turbid discharge is had loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism etc.(the 124th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Dioscoreae Septemlobae property of medicine hardship, flat.Return liver, stomach, urinary bladder channel.It is turbid to have dampness removing, the effect of wind-damp dispelling.Can treat stranguria marked by chyluria, nebulousurine, leukorrhagia, skin infection, eczema, rheumatic arthralgia etc.(the 2890th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Acori Graminei property of medicine suffering, hardship, tepor.GUIXIN, liver, spleen channel.Have and eliminate phlegm for resuscitation, removing dampness to restore normal function of the stomach, the effect of mind calming benefit will.Can treat the calentura coma, syncope due to accumulation of phlegm, forgetful, insomnia, tinnitus, deafness, fasting dysentery, rheumatic arthralgia etc.(the 854th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Linderae property of medicine suffering, temperature.Return spleen, stomach, liver, kidney, urinary bladder channel.Have promoting the circulation of QI to relieve pain, the effect of warming kidney for dispelling cold.It is vexed to treat fullness in the chest and hypochondrium, abdominal distention, headache, colic of cold type pain, dysmenorrhea and puerperal abdonimal pain, frequent micturition, the enuresis etc.(the 655th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Fructus Alpiniae Oxyphyllae, Rhizoma Smilacis Glabrae He Rhizoma Dioscoreae Septemlobae, is ministerial drug with Rhizoma Alismatis, Poria, the Radix Astragali, Radix Cyathulae, Radix Codonopsis, Cortex Phellodendri and Radix Salviae Miltiorrhizae; With the Rhizoma Acori Graminei and the Radix Linderae is adjuvant.All medicines are harmonious, and are total to the tool warming and recuperating the spleen and kidney, the effect that tonneauization is turbid.The treatment infertility due to non-liquefied sperm has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment infertility due to non-liquefied sperm of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat infertility due to non-liquefied sperm, and the prevention of infertility due to non-liquefied sperm is also had good effect, and the treatment infertility due to non-liquefied sperm has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment infertility due to non-liquefied sperm; Treatment infertility due to non-liquefied sperm patient 14 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 50%, and 5 examples that take a turn for the better account for 35.71%, and more 2 examples do not account for 14.29%, and total effective rate reaches 85.71%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 3 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 3 Fen Rhizoma Dioscoreae Septemlobae

2 parts of 2 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Smilacis Glabrae

2 parts of 2 portions of Cortex Phellodendris of 2 parts of Radix Codonopsis of Radix Cyathulae

2 parts of 1 part of Radix Salviae Miltiorrhizaes of 1 part of Radix Linderae of Rhizoma Acori Graminei

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment infertility due to non-liquefied sperm that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine preparation of treatment infertility due to non-liquefied sperm is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 1.5～6 Fen Rhizoma Dioscoreae Septemlobae

1.0～4 parts of 1.0～4 parts of Radixs Astragali of 1.5～6 parts of Poria of Rhizoma Smilacis Glabrae

1.0～4 parts of 1.0～4 portions of Cortex Phellodendris of 1.0～4 parts of Radix Codonopsis of Radix Cyathulae

1.0～4 parts of 0.1～2 part of Radix Salviae Miltiorrhizaes of 0.1～2 part of Radix Linderae of Rhizoma Acori Graminei.

2, the Chinese medicine preparation of treatment infertility due to non-liquefied sperm according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 2.5～3.5 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 2.5～3.5 Fen Rhizoma Dioscoreae Septemlobae

1.5～2.5 parts of 1.5～2.5 parts of Radixs Astragali of 2.5～3.5 parts of Poria of Rhizoma Smilacis Glabrae

1.5～2.5 parts of 1.5～2.5 portions of Cortex Phellodendris of 1.5～2.5 parts of Radix Codonopsis of Radix Cyathulae

1.5～2.5 parts of 0.5～1.5 part of Radix Salviae Miltiorrhizaes of 0.5～1.5 part of Radix Linderae of Rhizoma Acori Graminei.

3, the Chinese medicine preparation of treatment infertility due to non-liquefied sperm according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 3 portions of Rhizoma Alismatis of Fructus Alpiniae Oxyphyllae 3 Fen Rhizoma Dioscoreae Septemlobae

2 parts of 2 parts of Radixs Astragali of 3 parts of Poria of Rhizoma Smilacis Glabrae

2 parts of 2 portions of Cortex Phellodendris of 2 parts of Radix Codonopsis of Radix Cyathulae

2 parts of 1 part of Radix Salviae Miltiorrhizaes of 1 part of Radix Linderae of Rhizoma Acori Graminei.