CN101066328A - Chinese medicine composition for treating amenia - Google Patents

Abstract

The present invention provides Chinese medicine composition for treating amenia. The Chinese medicine composition is prepared with over ten kinds of Chinese medicinal materials, including eucommia bark, red sage, cyathula root, prepared tortoise shell, etc. It has the functions of benefiting qi, nourishing yin, promoting blood circulation and inducing menstrual flow. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine composition has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

A kind of Chinese medicine composition for the treatment of amenorrhea

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of amenorrhea, is that a kind of to treat amenorrhea be the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Menopathy is meant cycle, the menstrual period and unusual through the amount generation of all menstruations, and follows menstrual cycle the significant discomfort symptom to occur, or the relevant a series of symptoms that occurred before and after menopause are a class disease of feature.The woman over 18 one full year of life, and menstruation is not risen as yet, or interrupts person more than 6 months again behind the menstrual onset, is called " amenorrhea ".The former claims primary amenorrhea, and the latter claims secondary amenorrhea, ancient " morbid amenorrhea " or " amenorrhea ", " amenia ", " amenorrhea " etc. of claiming.Trimester of pregnancy, age of sucking or involutional amenorrhea belong to physiological phenomenon, do not make the amenorrhea opinion, and the maiden's menophania that has the amenorrhea phenomenon occurs in 2 years once in a while, can treat.Primary disease belongs to obstinate disease, and the course of disease is longer, and curative effect is relatively poor, and therefore, the Comprehensive Treatment that should adopt several different methods in case of necessity is to improve curative effect.Because of congenital genitals lack as, or organic damage will cause menolipsis person the day after tomorrow, because of Drug therapy is difficult to prove effective, does not belong to the present invention scope is discussed.Pathogeny mainly is to dash to appoint disorder of QI and blood, and void, real two aspects are arranged.Void person is owing to thanks to lose towards appointing, and its stream breaks in the source; Reality person dashes because of pathogen intercepts and appoints, and menses are obstructed.Cause the cause of disease complexity of amenorrhea, congenital factors is arranged, acquired disposition is also arranged; Also can be by menoxenia development, also have because of his disease to cause amenorrhea person.Common typing suffers from a deficiency of the kidney, insufficiency of the spleen, blood deficiency, qi depression to blood stasis, cold blood stasis and stagnation of phlegm-damp.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of amenorrhea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Radix Cyathulaes of 1.5～6 parts of Radix Astragali Preparatas of the Cortex Eucommiae

1.0～4 parts of 1.0～4 parts of Semen Cuscutae of 1.5～6 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

1.0～4 parts of 1.0～4 parts of Fructus Lycii of 1.0～4 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

1.0～4 parts of 0.1～2 part of Fructus Crataegi of 0.1～2 part of Fructus Corni of Flos Carthami

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 2.5～3.5 portions of Radix Cyathulaes of 2.5～3.5 parts of Radix Astragali Preparatas of the Cortex Eucommiae

1.5～2.5 parts of 1.5～2.5 parts of Semen Cuscutae of 2.5～3.5 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

1.5～2.5 parts of 1.5～2.5 parts of Fructus Lycii of 1.5～2.5 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

1.5～2.5 parts of 0.5～1.5 part of Fructus Crataegi of 0.5～1.5 part of Fructus Corni of Flos Carthami

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 3 portions of Radix Cyathulaes of 3 parts of Radix Astragali Preparatas of the Cortex Eucommiae

2 parts of 2 parts of Semen Cuscutae of 3 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

2 parts of 2 parts of Fructus Lycii of 2 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

2 parts of 1 part of Fructus Crataegi of 1 part of Fructus Corni of Flos Carthami

Drug action mechanism among the present invention is as follows:

Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Astragali Preparata property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).

Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, amenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The CARAPAX ET PIASTRUM TESTUDINIS PREPARATA property of medicine is salty, sweet, is slightly cold.Return liver, kidney, heart channel.Has nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, the effect of consolidating channel for hemostasis.Can treat deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and wriggling of the limbs, a little less than the muscles and bones flaccidity, children's's halogen door does not conform to, and the palpitation with fear insomnia is forgetful, menorrhagia, metrorrhagia and metrostaxis.(the 1608th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Crataegi property of medicine, sweet tepor.Return spleen, stomach, Liver Channel.Has promoting digestion and invigorating the stomach, the effect of circulation of qi promoting dissipating blood stasis.Can treat eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhea, puerperal abdonimal pain, lochiorrhea, hernia or painful and swollen testis, hyperlipemia etc.(the 226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Cortex Eucommiae, Radix Salviae Miltiorrhizae and Radix Astragali Preparata; With Radix Cyathulae, Radix Rehmanniae Preparata, Semen Cuscutae, Radix Angelicae Sinensis, CARAPAX ET PIASTRUM TESTUDINIS PREPARATA, Fructus Lycii and Fructus Crataegi is ministerial drug; With Flos Carthami and Fructus Corni is adjuvant.All medicines are harmonious, and are total to the tool supplementing QI and nourishing YIN, the effect of promoting blood circulation to restore menstrual flow.The treatment amenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment amenorrhea of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat amenorrhea, and the prevention of amenorrhea is also had good effect, and the treatment amenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment amenorrhea; Treatment amenorrhea patients 19 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 52.63%, and 7 examples that take a turn for the better account for 36.84%, and more 2 examples do not account for 10.53%, and total effective rate reaches 89.47%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 3 portions of Radix Cyathulaes of 3 parts of Radix Astragali Preparatas of the Cortex Eucommiae

2 parts of 2 parts of Semen Cuscutae of 3 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

2 parts of 2 parts of Fructus Lycii of 2 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

2 parts of 1 part of Fructus Crataegi of 1 part of Fructus Corni of Flos Carthami

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment amenorrhea that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (2)

1, a kind of Chinese medicine composition for the treatment of amenorrhea is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.5～6 portions of Radix Cyathulaes of 1.5～6 parts of Radix Astragali Preparatas of the Cortex Eucommiae

1.0～4 parts of 1.0～4 parts of Semen Cuscutae of 1.5～6 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

1.0～4 parts of 1.0～4 parts of Fructus Lycii of 1.0～4 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

1.0～4 parts of 0.1～2 part of Fructus Crataegi of 0.1～2 part of Fructus Corni of Flos Carthami.

2, a kind of Chinese medicine composition for the treatment of amenorrhea according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 2.5～3.5 portions of Radix Cyathulaes of 2.5～3.5 parts of Radix Astragali Preparatas of the Cortex Eucommiae

1.5～2.5 parts of 1.5～2.5 parts of Semen Cuscutae of 2.5～3.5 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

1.5～2.5 parts of 1.5～2.5 parts of Fructus Lycii of 1.5～2.5 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

1.5～2.5 parts of 0.5～1.5 part of Fructus Crataegi of 0.5～1.5 part of Fructus Corni of Flos Carthami.3, a kind of Chinese medicine composition for the treatment of amenorrhea according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 3 portions of Radix Cyathulaes of 3 parts of Radix Astragali Preparatas of the Cortex Eucommiae

2 parts of 2 parts of Semen Cuscutae of 3 parts of Radix Rehmanniae Preparata of Radix Salviae Miltiorrhizae

2 parts of 2 parts of Fructus Lycii of 2 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Radix Angelicae Sinensis

2 parts of 1 part of Fructus Crataegi of 1 part of Fructus Corni of Flos Carthami.