CN101049476A - Composition of Chinese traditional medicine for treating barrenness caused by lack of sperm - Google Patents
Composition of Chinese traditional medicine for treating barrenness caused by lack of sperm Download PDFInfo
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- CN101049476A CN101049476A CN 200710099251 CN200710099251A CN101049476A CN 101049476 A CN101049476 A CN 101049476A CN 200710099251 CN200710099251 CN 200710099251 CN 200710099251 A CN200710099251 A CN 200710099251A CN 101049476 A CN101049476 A CN 101049476A
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Abstract
A Chinese medicine for treating sterility caused by less sperm is prepared from more than 10 Chinese-medicinal materials including rehmannia root, burreed tuber, Chinese angelica root, dodder seed, etc. Its advantages are sure curative effect, high safety, and no toxic by effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of oligospermia infertility, is that a kind of oligospermia infertility for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Oligospermia also claims oligospermia, or the thin disease of sperm, refer to that sperm count (density) inspection is less than 2,000 ten thousand for every milliliter, or the sperm sum is lower than 4,000 ten thousand in the seminal fluid.Sperm concentration and fertility generally are proportionate, and oligospermia the most in masculine sterility more to be seen.Smith is at 1971 annual reports, and sperm count is lower than 2,000 ten thousand/ml, and the probability of becoming pregnant in the wife's side has only 19%.The analysis performance of clinical scholar to routine male infertility surplus 8000 once arranged, and oligospermia is 1245 examples, accounts for 14.6%.Primary disease belongs to categories such as the traditional Chinese medical science " oligospermia ", " seminal plasma ", " very thin ", " infertile ", " do not have and succeed ".Chinese medicine is thought, natural endowment deficiency, or chamber do not save, do not know to hold full, the consumption essence of being impairment of the kidney; Or five kinds of strain and seven kinds of impairment, for a long time sick and kidney; Insufficiency of kidney-YANG, the life fire declines, can not warm spleen sun, spleen not transporting and transforming nutrients from foodstuff is precise and tiny; Or QI and blood deficiency, damage of essence water is weary, the insufficiency of blood oligospermia.Or eating and drinking without temperance, hungry full imbalance, damage temper, it is little to fill the smart marrow etc. of mending to change spermatogenesis, all can cause few essence.The traditional Chinese medical science is divided into deficiency of kidney-essence clinically, syndrome of deficiency of kidney-YANG, and a little less than the spleen of suffering from a deficiency of the kidney, blood stasis body void, the damp and hot disease type Coryza Treated by Syndrome Differentiation that waits in smart chamber obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of oligospermia infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Rhizoma Polygonatis of 1.5～6 parts of Radix Angelicae Sinensis of the Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Bupleuri of 1.5～6 parts of Radix Codonopsis of Radix Rehmanniae
1.0～4 parts of 1.0～4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
1.0～4 parts of 1.0～4 portions of Rhizoma Dioscoreaes of 1.0～4 parts of Poria of Semen Cuscutae
0.1～2 part of 0.1～2 part of Rhizoma Curcumae of 0.1～2 part of rhizoma sparganic of Fructus Aurantii
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Polygonatis of 2.5～3.5 parts of Radix Angelicae Sinensis of the Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Bupleuri of 2.5～3.5 parts of Radix Codonopsis of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 1.5～2.5 parts of Poria of Semen Cuscutae
0.5～1.5 part of 0.5～1.5 part of Rhizoma Curcumae of 0.5～1.5 part of rhizoma sparganic of Fructus Aurantii
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Rhizoma Polygonatis of 3 parts of Radix Angelicae Sinensis of the Radix Astragali
2 parts of 2 parts of Radix Bupleuri of 3 parts of Radix Codonopsis of Radix Rehmanniae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Poria of Semen Cuscutae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Aurantii
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Polygonati property of medicine is sweet, and is flat.Return spleen, lung, kidney channel.Has nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, the effect of nourishing kidney replenishing essence.Can treat deficiency of YIN chronic cough, the xeropulmonary cough; Insufficiency of the spleen weak, the lack of appetite xerostomia is quenched one's thirst; The deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, the tinnitus order is dark, early whitening of beard and hair, the body weakness with emaciation is thin, wind favus disease etc.(the 2830th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Radix Astragali, Radix Rehmanniae and Radix Rehmanniae Preparata, is ministerial drug with Semen Cuscutae, Radix Angelicae Sinensis, Rhizoma Polygonati, Radix Codonopsis, Radix Bupleuri, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Poria and Rhizoma Dioscoreae; With Fructus Aurantii, rhizoma sparganic and Rhizoma Curcumae is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of benefiting QI and nourishing blood.The treatment oligospermia infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment oligospermia infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat oligospermia infertility, and the prevention of oligospermia infertility is also had good effect, and the treatment oligospermia infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment oligospermia infertility; Treatment oligospermia infertility patient 15 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 40%, and 7 examples that take a turn for the better account for 46.67%, and more 2 examples do not account for 13.33%, and total effective rate reaches 86.67%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Rhizoma Polygonatis of 3 parts of Radix Angelicae Sinensis of the Radix Astragali
2 parts of 2 parts of Radix Bupleuri of 3 parts of Radix Codonopsis of Radix Rehmanniae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Poria of Semen Cuscutae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Aurantii
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment oligospermia infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine composition for the treatment of oligospermia infertility is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Rhizoma Polygonatis of 1.5～6 parts of Radix Angelicae Sinensis of the Radix Astragali
1.0～4 parts of 1.0～4 parts of Radix Bupleuri of 1.5～6 parts of Radix Codonopsis of Radix Rehmanniae
1.0～4 parts of 1.0～4 parts of Rhizoma Atractylodis Macrocephalaes of 1.5～6 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
1.0～4 parts of 1.0～4 portions of Rhizoma Dioscoreaes of 1.0～4 parts of Poria of Semen Cuscutae
0.1～2 part of 0.1～2 part of Rhizoma Curcumae of 0.1～2 part of rhizoma sparganic of Fructus Aurantii
2, a kind of Chinese medicine composition for the treatment of oligospermia infertility according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Polygonatis of 2.5～3.5 parts of Radix Angelicae Sinensis of the Radix Astragali
1.5～2.5 parts of 1.5～2.5 parts of Radix Bupleuri of 2.5～3.5 parts of Radix Codonopsis of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Atractylodis Macrocephalaes of 2.5～3.5 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 1.5～2.5 parts of Poria of Semen Cuscutae
0.5～1.5 part of 0.5～1.5 part of Rhizoma Curcumae of 0.5～1.5 part of rhizoma sparganic of Fructus Aurantii
3, a kind of Chinese medicine composition for the treatment of oligospermia infertility according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Rhizoma Polygonatis of 3 parts of Radix Angelicae Sinensis of the Radix Astragali
2 parts of 2 parts of Radix Bupleuri of 3 parts of Radix Codonopsis of Radix Rehmanniae
2 parts of 2 parts of Rhizoma Atractylodis Macrocephalaes of 3 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Poria of Semen Cuscutae
1 part of 1 part of Rhizoma Curcumae of 1 part of rhizoma sparganic of Fructus Aurantii.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102085269A (en) * | 2011-01-28 | 2011-06-08 | 浙江大学 | Traditional Chinese medicine composition for treating polycystic ovary syndrome (PCOS) and application thereof |
| CN110960645A (en) * | 2019-12-17 | 2020-04-07 | 广州小娃儿医药科技有限公司 | Traditional Chinese medicine composition for promoting spermatogenesis, improving quality and reducing deformity |
| CN117357621A (en) * | 2023-11-21 | 2024-01-09 | 江苏省中医院 | Traditional Chinese medicine compound for improving sperm energy metabolism and preparation method and application thereof |
-
2007
- 2007-05-16 CN CN 200710099251 patent/CN101049476A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102085269A (en) * | 2011-01-28 | 2011-06-08 | 浙江大学 | Traditional Chinese medicine composition for treating polycystic ovary syndrome (PCOS) and application thereof |
| CN102085269B (en) * | 2011-01-28 | 2012-02-22 | 浙江大学 | Traditional Chinese medicine composition for treating polycystic ovary syndrome (PCOS) and application thereof |
| CN110960645A (en) * | 2019-12-17 | 2020-04-07 | 广州小娃儿医药科技有限公司 | Traditional Chinese medicine composition for promoting spermatogenesis, improving quality and reducing deformity |
| CN117357621A (en) * | 2023-11-21 | 2024-01-09 | 江苏省中医院 | Traditional Chinese medicine compound for improving sperm energy metabolism and preparation method and application thereof |
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