CN101129612A - Chinese patent drug for treating alopecia areata - Google Patents

Abstract

The invention relates to a Chinese medicament for treating alopecia areata, which is prepared from more than ten kinds of Chinese medicinal herbs including raw astragalus root, prepared rehmannia root, fleece-flower root and ligustrum japonicum. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese patent medicine for the treatment of alopecia areata

Technical field

The present invention relates to a kind of Chinese patent medicine for the treatment of alopecia areata, is that a kind of alopecia areata for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Alopecia areata has another name called bald, the circular alopecia of circle.Be the alopecia of a kind of circumscribed patch shape, take place suddenly, tendency of recurrence is arranged through low.Normal with hair flaking, lesion scalp on the statistics, NIP, no conscious sympton are characteristics, if whole scalp and hair-care all comes off and is called alopecia totalis.The whole body hair person that all do not come off is called alopecia universalis.The prevalence of alopecia areata is about 0.1% among the crowd, and any age all can fall ill, and is common between 5～40 years old, and wherein person between twenty and fifty are many, and both sexes all can be got involved, and do not have the difference in obvious region, season.There is alopecia areata patient's pathological changes of 95% to be confined to scalp approximately, has 4%～30% alopecia areata patient to develop into alopecia universalis approximately.Alopecia areata belongs to Chinese medicine " alopecia areata " category, is commonly called as " ghost lick head ", " alopecia areata ", " deals with " in the Huangdi's Internal Classics, the description of symptoms such as " trichomadesis ", " alopecia areata,trichomadesis " is to primary disease record the earliest.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of the liver and kindey, stagnation of liver-QI blood stasis, blood hot air wind producing, QI and blood deficiency clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of alopecia areata.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

1.0～4 parts of 1.0～4 parts of Concha Ostreae of 1.5～6 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

0.1～2 part of 1.0～4 portions of Caulis Spatholobi of 1.5～6 parts of Fructus Lycii of Radix Polygoni Multiflori

0.1～2 part of 1.0～4 portions of Herba Ecliptae of 1.5～6 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

0.1～2 part of 1.0～4 parts of Radix Polygalae of 1.0～4 parts of Semen Cuscutae of Radix Astragali.

The weight proportion of each crude drug of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 parts of Concha Ostreae of 2.5～3.5 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

0.5～1.5 part of 1.5～2.5 portions of Caulis Spatholobi of 2.5～3.5 parts of Fructus Lycii of Radix Polygoni Multiflori

0.5～1.5 part of 1.5～2.5 portions of Herba Ecliptae of 2.5～3.5 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

0.5～1.5 part of 1.5～2.5 parts of Radix Polygalae of 1.5～2.5 parts of Semen Cuscutae of Radix Astragali.

The weight proportion of each crude drug of optimum formula of the present invention is:

2 parts of 2 parts of Concha Ostreae of 3 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

1 part of 2 portions of Caulis Spatholobi of 3 parts of Fructus Lycii of Radix Polygoni Multiflori

1 part of 2 portions of Herba Ecliptae of 3 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

1 part of 2 parts of Radix Polygalae of 2 parts of Semen Cuscutae of Radix Astragali.

Drug action mechanism among the present invention is as follows:

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).

Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Semen Sesami Nigrum property of medicine is sweet, and property is flat.Return the liver,spleen,kidney warp.Effect with nourish blood benefit essence, loosening bowel to relieve constipation.Can treat the dizziness and tinnitus due to the Liver and kidney asthenia of essence and blood, waist foot flaccidity is soft, early whitening of beard and hair, and scaly dry skin, the dryness of the intestine constipation, married woman's breast is few, carbuncle skin ulcer eczema, wind leprosy scrofula infections, infantile scrofula, burn, hemorrhoid etc.(the 3338th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Caulis Spatholobi property of medicine hardship, little sweet, temperature.Return liver, kidney channel.Has relaxing muscles and tendons to promote blood circulation, the effect of nourishing blood for regulating menstruation.Can treat numb hand and foot, quadriplegia, rheumatic arthralgia, anemia, menoxenia, dysmenorrhea, amenorrhea etc.(the 1689th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Polygalae property of medicine suffering, hardship, tepor.GUIXIN, lung, kidney channel.Have mind tranquilizing and the heart calming, eliminate the phlegm and have one's ideas straightened out, the effect of removing toxic substances and promoting subsidence of swelling.Can treat irritability, the palpitation with fear insomnia, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain etc.(the 1436th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae Preparata, Radix Polygoni Multiflori and Semen Sesami Nigrum; With Radix Astragali, Fructus Ligustri Lucidi, Fructus Lycii, Radix Angelicae Sinensis, Semen Cuscutae and Concha Ostreae is ministerial drug; With Caulis Spatholobi, Herba Ecliptae and Radix Polygalae is adjuvant.All medicines are harmonious, tool enriching yin and nourishing kidney altogether, the effect of benefiting QI and nourishing blood.The treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment alopecia areata of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat alopecia areata, and the prevention of alopecia areata is also had good effect, and the treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment alopecia areata; Treatment alopecia areata patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 45%, and invalid 1 example accounts for 5%, and total effective rate reaches 95%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

2 parts of 2 parts of Concha Ostreae of 3 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

1 part of 2 portions of Caulis Spatholobi of 3 parts of Fructus Lycii of Radix Polygoni Multiflori

1 part of 2 portions of Herba Ecliptae of 3 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

1 part of 2 parts of Radix Polygalae of 2 parts of Semen Cuscutae of Radix Astragali.

Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment alopecia areata that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1. Chinese patent medicine for the treatment of alopecia areata is characterized in that it is made by following raw materials by weight proportions:

1.0～4 parts of 1.0～4 parts of Concha Ostreae of 1.5～6 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

0.1～2 part of 1.0～4 portions of Caulis Spatholobi of 1.5～6 parts of Fructus Lycii of Radix Polygoni Multiflori

0.1～2 part of 1.0～4 portions of Herba Ecliptae of 1.5～6 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

0.1～2 part of 1.0～4 parts of Radix Polygalae of 1.0～4 parts of Semen Cuscutae of Radix Astragali.

2. a kind of Chinese patent medicine for the treatment of alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:

1.5～2.5 parts of 1.5～2.5 parts of Concha Ostreae of 2.5～3.5 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

0.5～1.5 part of 1.5～2.5 portions of Caulis Spatholobi of 2.5～3.5 parts of Fructus Lycii of Radix Polygoni Multiflori

0.5～1.5 part of 1.5～2.5 portions of Herba Ecliptae of 2.5～3.5 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

0.5～1.5 part of 1.5～2.5 parts of Radix Polygalae of 1.5～2.5 parts of Semen Cuscutae of Radix Astragali.

3. a kind of Chinese patent medicine for the treatment of alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:

2 parts of 2 parts of Concha Ostreae of 3 parts of Fructus Ligustri Lucidi of Radix Rehmanniae Preparata

1 part of 2 portions of Caulis Spatholobi of 3 parts of Fructus Lycii of Radix Polygoni Multiflori

1 part of 2 portions of Herba Ecliptae of 3 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum

1 part of 2 parts of Radix Polygalae of 2 parts of Semen Cuscutae of Radix Astragali.