CN101116698A - Chinese medicine preparation for treating alopecia areata - Google Patents

Chinese medicine preparation for treating alopecia areata Download PDF

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Publication number
CN101116698A
CN101116698A CNA2007101209616A CN200710120961A CN101116698A CN 101116698 A CN101116698 A CN 101116698A CN A2007101209616 A CNA2007101209616 A CN A2007101209616A CN 200710120961 A CN200710120961 A CN 200710120961A CN 101116698 A CN101116698 A CN 101116698A
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China
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parts
fructus
chinese medicine
alopecia areata
medicine preparation
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CNA2007101209616A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101209616A priority Critical patent/CN101116698A/en
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Abstract

The invention relates to a Chinese traditional medicine preparation in treating alopecia, which adopts more than ten kinds of Chinese herbal medicine such as medlar, dodder, mulberry syncarp, fructus psoraleae and so on as raw materials. The preparation has efficacy of nourishing and invigorating the kidney-Yin, supplementing the Qi and nourishing the blood. Based on the dialetic treatment of the traditional Chinese medicine, the invention is developed by a latest modern scientific research production. The invention aims to provide a Chinese traditional medicine preparation in treating alopecia. The preparation is characterized in assuring curative effect, safety, convenience, innocuity, non-side effect and low cost.

Description

A kind of Chinese medicine preparation of treatment alopecia areata
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of alopecia areata, is that a kind of alopecia areata for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Alopecia areata has another name called bald, the circular alopecia of circle.Be the alopecia of a kind of circumscribed patch shape, take place suddenly, tendency of recurrence is arranged through low.Normal with hair flaking, lesion scalp on the statistics, NIP, no conscious sympton are characteristics, if whole scalp and hair-care all comes off and is called alopecia totalis.The whole body hair person that all do not come off is called alopecia universalis.The prevalence of alopecia areata is about 0.1% among the crowd, and any age all can fall ill, and is common between 5~40 years old, and wherein person between twenty and fifty are many, and both sexes all can be got involved, and do not have the difference in obvious region, season.There is alopecia areata patient's pathological changes of 95% to be confined to scalp approximately, has 4%~30% alopecia areata patient to develop into alopecia universalis approximately.Alopecia areata belongs to Chinese medicine " alopecia areata " category, is commonly called as " ghost lick head ", " alopecia areata ", " deals with " in the Huangdi's Internal Classics, the description of symptoms such as " trichomadesis ", " alopecia areata,trichomadesis " is to primary disease record the earliest.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of the liver and kindey, stagnation of liver-QI blood stasis, blood hot air wind producing, QI and blood deficiency clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of alopecia areata.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 portions of Fructus Chaenomelis of 1.5~6 parts of Radix Codonopsis of Fructus Lycii
0.1~2 part of 1.0~4 parts of Fructus Psoraleae of 1.5~6 parts of Poria of Semen Cuscutae
0.1~2 part of 1.0~4 parts of Fructus Corni of 1.5~6 parts of Radix Angelicae Sinensis of Fructus Mori
0.1~2 part of 1.0~4 parts of Cortex Dictamni of 1.0~4 parts of Folium Mori of Semen Sesami Nigrum.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 portions of Fructus Chaenomelis of 2.5~3.5 parts of Radix Codonopsis of Fructus Lycii
0.5~1.5 part of 1.5~2.5 parts of Fructus Psoraleae of 2.5~3.5 parts of Poria of Semen Cuscutae
0.5~1.5 part of 1.5~2.5 parts of Fructus Corni of 2.5~3.5 parts of Radix Angelicae Sinensis of Fructus Mori
0.5~1.5 part of 1.5~2.5 parts of Cortex Dictamni of 1.5~2.5 parts of Folium Mori of Semen Sesami Nigrum.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 2 portions of Fructus Chaenomelis of 3 parts of Radix Codonopsis of Fructus Lycii
1 part of 2 parts of Fructus Psoraleae of 3 parts of Poria of Semen Cuscutae
1 part of 2 parts of Fructus Corni of 3 parts of Radix Angelicae Sinensis of Fructus Mori
1 part of 2 parts of Cortex Dictamni of 2 parts of Folium Mori of Semen Sesami Nigrum.
Drug action mechanism among the present invention is as follows:
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Mori property of medicine is sweet, sour, and is cold.Return liver, kidney channel.Have nourishing YIN and benefiting blood, promote the production of body fluid, the effect of intestine moistening.Can treat having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, the soreness of waist, dryness of the intestine constipation, tinea alba etc. are quenched one's thirst in insomnia.(the 2791st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Sesami Nigrum property of medicine is sweet, and property is flat.Return the liver,spleen,kidney warp.Effect with nourish blood benefit essence, loosening bowel to relieve constipation.Can treat the dizziness and tinnitus due to the Liver and kidney asthenia of essence and blood, waist foot flaccidity is soft, early whitening of beard and hair, and scaly dry skin, the dryness of the intestine constipation, married woman's breast is few, carbuncle skin ulcer eczema, wind leprosy scrofula infections, infantile scrofula, burn, hemorrhoid etc.(the 3338th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Folium Mori property of medicine hardship, sweet, cold.Return lung, Liver Channel.Has dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, the effect of liver heat removing and eyesight improving.Can treat anemopyretic cold, pathogenic wind-warm is from the beginning of, fever and headache, perspiration and aversion to wind, cough chest pain; Or dryness of the lung dry cough without phlegm, dry throat and mouth; Disturb conjunctival congestion and swelling pain etc. on wind heat and the liver-yang.(the 2780th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Chaenomelis property of medicine, temperature.Return liver, spleen, stomach warp.Has relaxing muscles and tendons and activating QI and blood in the collateral, the effect of stomach function regulating removing dampness.Can treat rheumatic arthralgia, vague aching of limbs, the contracture of muscle arteries and veins, the convulsion of vomiting and diarrhoea, beriberi, edema, dysentery etc.(the 474th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Psoraleae property of medicine suffering, hardship, temperature.Return kidney, spleen channel.Has reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal effect.Can treat the deficiency and coldness lumbago, sexual impotence spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, dyspnea due to deficiency, vitiligo, alopecia areata, psoriasis etc.(the 1647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Dictamni property of medicine hardship, salty, cold.Return spleen, stomach warp.Has heat clearing and damp drying, dispelling wind for relieving itching, antidotal effect.Can treat the rubella eczema due to the wind heat noxious dampness, scabies, jaundice, rheumatism pyretic arthralgia etc.(the 1019th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Fructus Lycii, Semen Cuscutae and Fructus Mori; With Semen Sesami Nigrum, Radix Codonopsis, Poria, Radix Angelicae Sinensis, Folium Mori and Fructus Corni is ministerial drug; With Fructus Chaenomelis, Fructus Psoraleae and Cortex Dictamni is adjuvant.All medicines are harmonious, and are total to the tool nourishing kidney yin, the effect of benefiting QI and nourishing blood.The treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment alopecia areata of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat alopecia areata, and the prevention of alopecia areata is also had good effect, and the treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment alopecia areata; Treatment alopecia areata patient 26 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.14 examples of fully recovering account for 53.84%, and 9 examples that take a turn for the better account for 34.62%, and more 3 examples do not account for 11.54%, and total effective rate reaches 88.46%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
1 part of 2 portions of Fructus Chaenomelis of 3 parts of Radix Codonopsis of Fructus Lycii
1 part of 2 parts of Fructus Psoraleae of 3 parts of Poria of Semen Cuscutae
1 part of 2 parts of Fructus Corni of 3 parts of Radix Angelicae Sinensis of Fructus Mori
1 part of 2 parts of Cortex Dictamni of 2 parts of Folium Mori of Semen Sesami Nigrum.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment alopecia areata that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1. a kind of Chinese medicine preparation of treatment alopecia areata is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 1.0~4 portions of Fructus Chaenomelis of 1.5~6 parts of Radix Codonopsis of Fructus Lycii
0.1~2 part of 1.0~4 parts of Fructus Psoraleae of 1.5~6 parts of Poria of Semen Cuscutae
0.1~2 part of 1.0~4 parts of Fructus Corni of 1.5~6 parts of Radix Angelicae Sinensis of Fructus Mori
0.1~2 part of 1.0~4 parts of Cortex Dictamni of 1.0~4 parts of Folium Mori of Semen Sesami Nigrum.
2. a kind of Chinese medicine preparation of treatment alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 1.5~2.5 portions of Fructus Chaenomelis of 2.5~3.5 parts of Radix Codonopsis of Fructus Lycii
0.5~1.5 part of 1.5~2.5 parts of Fructus Psoraleae of 2.5~3.5 parts of Poria of Semen Cuscutae
0.5~1.5 part of 1.5~2.5 parts of Fructus Corni of 2.5~3.5 parts of Radix Angelicae Sinensis of Fructus Mori
0.5~1.5 part of 1.5~2.5 parts of Cortex Dictamni of 1.5~2.5 parts of Folium Mori of Semen Sesami Nigrum.
3. a kind of Chinese medicine preparation of treatment alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 2 portions of Fructus Chaenomelis of 3 parts of Radix Codonopsis of Fructus Lycii
1 part of 2 parts of Fructus Psoraleae of 3 parts of Poria of Semen Cuscutae
1 part of 2 parts of Fructus Corni of 3 parts of Radix Angelicae Sinensis of Fructus Mori
1 part of 2 parts of Cortex Dictamni of 2 parts of Folium Mori of Semen Sesami Nigrum.
CNA2007101209616A 2007-08-29 2007-08-29 Chinese medicine preparation for treating alopecia areata Pending CN101116698A (en)

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Application Number Priority Date Filing Date Title
CNA2007101209616A CN101116698A (en) 2007-08-29 2007-08-29 Chinese medicine preparation for treating alopecia areata

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CN101116698A true CN101116698A (en) 2008-02-06

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101391047B (en) * 2008-10-16 2011-08-03 刘振普 Traditional Chinese medicine preparation for treating trichonosis
CN107362321A (en) * 2016-05-11 2017-11-21 俞成莲 A kind of Chinese medicine composition of hair growth

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101391047B (en) * 2008-10-16 2011-08-03 刘振普 Traditional Chinese medicine preparation for treating trichonosis
CN107362321A (en) * 2016-05-11 2017-11-21 俞成莲 A kind of Chinese medicine composition of hair growth

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Open date: 20080206